Joanna Groom

Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment

Amania A Sheikh, Joanna R Groom

Journal article  |  2020  |  Cellular & Molecular Immunology

Hhex drives B cells down memory lane

Kim L Good-Jacobson, Joanna R Groom

Journal article  |  2020  |  Nature Immunology

Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation.

Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Yi Ju, Wenbo Jiang, Verena C Wimmer, Brigette C Duckworth, Joanna R Groom, Frank Caruso, Masaru Kanekiyo, Stephen J Kent, Adam K Wheatley

Journal article  |  2020  |  JCI Insight

Protein-based, self-assembling nanoparticles elicit superior immunity compared with soluble protein vaccines, but the immune mecha..

Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria

Ann Ly, Yang Liao, Halina Pietrzak, Lisa J Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z Qin, Joanna R Groom, Gabrielle T Belz, Kim L Good-Jacobson, Wei Shi, Axel Kallies, Diana S Hansen

Journal article  |  2019  |  Cell Reports

Despite the key role that antibodies play in protection, the cellular processes mediating the acquisition of humoral immunity agai..

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

Jai Rautela, Laura F Dagley, Tobias Kratina, Angaleena Anthony, Wilford Goh, Elliot Surgenor, Rebecca B Delconte, Andrew I Webb, Ngaire Elwood, Joanna R Groom, Fernando Souza-Fonseca-Guimaraes, Lynn Corcoran, Nicholas D Huntington

Journal article  |  2019  |  Molecular Immunology

NK cells are cytotoxic lymphocytes with a key role in limiting tumour metastases. In mice, the NK cell lineage continually express..

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection

Amania A Sheikh, Lucy Cooper, Meiqi Feng, Fernando Souza-Fonseca-Guimaraes, Fanny Lafouresse, Brigette C Duckworth, Nicholas D Huntington, James J Moon, Marc Pellegrini, Stephen L Nutt, Gabrielle T Belz, Kim L Good-Jacobson, Joanna R Groom

Journal article  |  2019  |  Cell Reports

Regulators of T-cell fate: Integration of cell migration, differentiation and function

Joanna R Groom

Journal article  |  2019  |  Immunological Reviews

Type I interferon induces CXCL13 to support ectopic germinal center formation

Alice E Denton, Silvia Innocentin, Edward J Carr, Barry M Bradford, Fanny Lafouresse, Neil A Mabbott, Urs Morbe, Burkhard Ludewig, Joanna R Groom, Kim L Good-Jacobson, Michelle A Linterman

Journal article  |  2019  |  Journal of Experimental Medicine

Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses

Lucy Cooper, Lauren Hailes, Amania Sheikh, Colby Zaph, Gabrielle T Belz, Joanna R Groom, Kim L Good-Jacobson

Journal article  |  2018  |  PLoS One

Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation

Casper Marsman, Fanny Lafouresse, Yang Liao, Tracey M Baldwin, Lisa A Mielke, Yifang Hu, Matthias Mack, Paul J Hertzog, Carolyn A de Graaf, Wei Shi, Joanna R Groom

Journal article  |  2018  |  Immunology and Cell Biology