Joanna Groom

Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria

Ann Ly, Yang Liao, Halina Pietrzak, Lisa J Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z Qin, Joanna R Groom, Gabrielle T Belz, Kim L Good-Jacobson, Wei Shi, Axel Kallies, Diana S Hansen

Journal article  |  2019  |  Cell Reports

Despite the key role that antibodies play in protection, the cellular processes mediating the acquisition of humoral immunity agai..

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

Jai Rautela, Laura F Dagley, Tobias Kratina, Angaleena Anthony, Wilford Goh, Elliot Surgenor, Rebecca B Delconte, Andrew I Webb, Ngaire Elwood, Joanna R Groom, Fernando Souza-Fonseca-Guimaraes, Lynn Corcoran, Nicholas D Huntington

Journal article  |  2019  |  Molecular Immunology

NK cells are cytotoxic lymphocytes with a key role in limiting tumour metastases. In mice, the NK cell lineage continually express..

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection

Amania A Sheikh, Lucy Cooper, Meiqi Feng, Fernando Souza-Fonseca-Guimaraes, Fanny Lafouresse, Brigette C Duckworth, Nicholas D Huntington, James J Moon, Marc Pellegrini, Stephen L Nutt, Gabrielle T Belz, Kim L Good-Jacobson, Joanna R Groom

Journal article  |  2019  |  Cell Reports

Regulators of T-cell fate: Integration of cell migration, differentiation and function

Joanna R Groom

Journal article  |  2019  |  Immunological Reviews

Type I interferon induces CXCL13 to support ectopic germinal center formation

Alice E Denton, Silvia Innocentin, Edward J Carr, Barry M Bradford, Fanny Lafouresse, Neil A Mabbott, Urs Morbe, Burkhard Ludewig, Joanna R Groom, Kim L Good-Jacobson, Michelle A Linterman

Journal article  |  2019  |  Journal of Experimental Medicine

Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses

Lucy Cooper, Lauren Hailes, Amania Sheikh, Colby Zaph, Gabrielle T Belz, Joanna R Groom, Kim L Good-Jacobson

Journal article  |  2018  |  PLOS ONE

Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation

Casper Marsman, Fanny Lafouresse, Yang Liao, Tracey M Baldwin, Lisa A Mielke, Yifang Hu, Matthias Mack, Paul J Hertzog, Carolyn A de Graaf, Wei Shi, Joanna R Groom

Journal article  |  2018  |  Immunology and Cell Biology

A Task Force Against Local Inflammation and Cancer: Lymphocyte Trafficking to and Within the Skin

Fanny Lafouresse, Joanna R Groom

Journal article  |  2018  |  Frontiers in Immunology

Editorial overview: Lymphocyte development and activation

Stephen L Nutt, Joanna R Groom

Journal article  |  2018  |  Current Opinion in Immunology

Friends help make lasting memories

Fanny Lafouresse, Joanna R Groom

Journal article  |  2018  |  Immunology and Cell Biology

Tailoring Immune Responses toward Autoimmunity: Transcriptional Regulators That Drive the Creation and Collusion of Autoreactive Lymphocytes

Kim L Good-Jacobson, Joanna R Groom

Journal article  |  2018  |  Frontiers in Immunology

Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation

Ali Zaid, Jyh Liang Hor, Susan N Christo, Joanna R Groom, William R Heath, Laura K Mackay, Scott N Mueller

Journal article  |  2017  |  The Journal of Immunology

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells

Angela Pizzolla, Zhongfang Wang, Joanna R Groom, Katherine Kedzierska, Andrew G Brooks, Patrick C Reading, Linda M Wakim

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

Dana Piovesan, Jessica Tempany, Andrea Di Pietro, Inge Baas, Callisthenis Yiannis, Kristy O'Donnell, Yunshun Chen, Victor Peperzak, Gabrielle T Belz, Charles R Mackay, Gordon K Smyth, Joanna R Groom, David M Tarlinton, Kim L Good-Jacobson

Journal article  |  2017  |  Cell Reports

Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease

Jillian M Richmond, Dinesh S Bangari, Kingsley I Essien, Sharif D Currimbhoy, Joanna R Groom, Amit G Pandya, Michele E Youd, Andrew D Luster, John E Harris

Journal article  |  2017  |  Journal of Investigative Dermatology

Moving to the suburbs: T-cell positioning within lymph nodes during activation and memory

Joanna R Groom

Journal article  |  2015  |  Immunology and Cell Biology

Chemokines in cellular positioning and human disease

Joanna R Groom

Journal article  |  2015  |  Immunology and Cell Biology

Nfil3 is required for the development of all innate lymphoid cell subsets

Cyril Seillet, Lucille C Rankin, Joanna R Groom, Lisa A Mielke, Julie Tellier, Michael Chopin, Nicholas D Huntington, Gabrielle T Belz, Sebastian Carotta

Journal article  |  2014  |  Journal of Experimental Medicine

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine

Matthew C Woodruff, Balthasar A Heesters, Caroline N Herndon, Joanna R Groom, Paul G Thomas, Andrew D Luster, Shannon J Turley, Michael C Carroll

Journal article  |  2014  |  Journal of Experimental Medicine

Id2 represses E2A-mediated activation of IL-10 expression in T cells

Frederick Masson, Margherita Ghisi, Joanna R Groom, Axel Kallies, Cyril Seillet, Ricky W Johnstone, Stephen L Nutt, Gabrielle T Belz

Journal article  |  2014  |  Blood

TCF-1 Controls ILC2 and NKp46( )ROR gamma t( ) Innate Lymphocyte Differentiation and Protection in Intestinal Inflammation

Lisa A Mielke, Joanna R Groom, Lucille C Rankin, Cyril Seillet, Frederick Masson, Tracy Putoczki, Gabrielle T Belz

Journal article  |  2013  |  Journal of Immunology

The transcription factor T-bet is essential for the development of NKp46( ) innate lymphocytes via the Notch pathway (vol 14, pg 389, 2013)

Lucille Rankin, Joanna R Groom, Michael Chopin, Marco J Herold, Jennifer A Walker, Lisa A Mielke, Andrew NJ McKenzie, Sebastian Carotta, Stephen L Nutt, Gabrielle T Belz

Journal article  |  2013  |  Nature Immunology

Retinoic acid expression associates with enhanced IL-22 production by gamma delta T cells and innate lymphoid cells and attenuation of intestinal inflammation

Lisa A Mielke, Sarah A Jones, Mathilde Raverdeau, Rowan Higgs, Anna Stefanska, Joanna R Groom, Alicja Misiak, Lara S Dungan, Caroline E Sutton, Gundula Streubel, Adrian P Bracken, Kingston HG Mills

Journal article  |  2013  |  Journal of Experimental Medicine

The transcription factor T-bet is essential for the development of NKp46( ) innate lymphocytes via the Notch pathway

Lucille C Rankin, Joanna R Groom, Michael Chopin, Marco J Herold, Jennifer A Walker, Lisa A Mielke, Andrew NJ McKenzie, Sebastian Carotta, Stephen L Nutt, Gabrielle T Belz

Journal article  |  2013  |  Nature Immunology

Diversity, function, and transcriptional regulation of gut innate lymphocytes

Lucille Rankin, Joanna Groom, Lisa A Mielke, Cyril Seillet, Gabrielle T Belz

Journal article  |  2013  |  Frontiers in Immunology

CXCR3 Chemokine Receptor-Ligand Interactions in the Lymph Node Optimize CD4( ) T Helper 1 Cell Differentiation

Joanna R Groom, Jillian Richmond, Thomas T Murooka, Elizabeth W Sorensen, Jung Hwan Sung, Katherine Bankert, Ulrich H von Andrian, James J Moon, Thorsten R Mempel, Andrew D Luster

Journal article  |  2012  |  Immunity

Chemokine Guidance of Central Memory T Cells Is Critical for Antiviral Recall Responses in Lymph Nodes

Jung Hwan Sung, Han Zhang, E Ashley Moseman, David Alvarez, Matteo Iannacone, Sarah E Henrickson, Juan C de la Torre, Joanna R Groom, Andrew D Luster, Ulrich H von Andrian

Journal article  |  2012  |  Cell

CXCR3 in T cell function

Joanna R Groom, Andrew D Luster

Journal article  |  2011  |  Experimental Cell Research

Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice

Carrie A Fletcher, Joanna R Groom, Blanche Woehl, Helen Leung, Charles Mackay, Fabienne Mackay

Journal article  |  2011  |  Journal of Autoimmunity

CXCR3 ligands: redundant, collaborative and antagonistic functions

Joanna R Groom, Andrew D Luster

Journal article  |  2011  |  Immunology and Cell Biology

Increased CD4( )Foxp3( ) T Cells in BAFF-Transgenic Mice Suppress T Cell Effector Responses

Stacey Walters, Kylie E Webster, Andrew Sutherland, Sandra Gardam, Joanna Groom, David Liuwantara, Eliana Marino, Jessica Thaxton, Anita Weinberg, Fabienne Mackay, Robert Brink, Jonathon Sprent, Shane T Grey

Journal article  |  2009  |  The Journal of Immunology

Marginal-zone B-Cells of Nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-Cells

Eliana Marino, Marcel Batten, Joanna Groom, Stacey Walters, David Liuwantara, Fabienne Mackay, Shane T Grey

Journal article  |  2008  |  Diabetes

B cells flying solo

Joanna Groom, Fabienne Mackay

Journal article  |  2008  |  Immunology and Cell Biology

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

Frederic Sierro, Christine Biben, Laura Martinez-Munoz, Mario Mellado, Richard M Ransohoff, Meizhang Li, Blanche Woehl, Helen Leung, Joanna Groom, Marcel Batten, Richard P Harvey, Carlos Martinez-A, Charles R Mackay, Fabienne Mackay

Journal article  |  2007  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An important role for B-cell activation factor and B cells in the pathogenesis of Sjogren's syndrome

Fabienne Mackaya, Joanna R Groom, Stuart G Tangye

Journal article  |  2007  |  Current Opinion in Rheumatology

BAFF and MyD88 signals promote a lupuslike disease independent of T cells

Joanna R Groom, Carrie A Fletcher, Stacey N Walters, Shane T Grey, Sally V Watt, Mathew J Sweet, Mark J Smyth, Charles R Mackay, Fabienne Mackay

Journal article  |  2007  |  Journal of Experimental Medicine

Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells

Carrie A Fletcher, Andrew PR Sutherland, Joanna R Groom, Marcel L Batten, Lai Guan Ng, Jennifer Gommerman, Fabienne Mackay

Journal article  |  2006  |  European Journal of Immunology

B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells

LG Ng, APR Sutherland, R Newton, F Qian, TG Cachero, ML Scott, JS Thompson, J Wheway, T Chtanova, J Groom, IJ Sutton, C Xin, SG Tangye, SL Kalled, F Mackay, CR Mackay

Journal article  |  2004  |  The Journal of Immunology

TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma

M Batten, C Fletcher, LG Ng, J Groom, J Wheway, Y Laabi, XG Xin, P Schneider, J Tschopp, CR Mackay, F Mackay

Journal article  |  2004  |  The Journal of Immunology

Levels of BAFF in serum in primary biliary cirrhosis and autoimmune diabetes

IR Mackay, J Groom, CR Mackay

Journal article  |  2002  |  Autoimmunity

The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses

JA Tarrant, J Groom, D Metcalf, RL Li, B Borobokas, MD Wright, D Tarlinton, L Robb

Journal article  |  2002  |  Molecular and Cellular Biology

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome

J Groom, SL Kalled, AH Cutler, C Olson, SA Woodcock, P Schneider, J Tschopp, TG Cachero, M Batten, J Wheway, D Mauri, D Cavill, TP Gordon, CR Mackay, F Mackay

Journal article  |  2002  |  Journal of Clinical Investigation

Molecular characterisation of mouse and human TSSC6: evidence that TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifically in haematopoietic organs

L Robb, J Tarrant, J Groom, M Ibrahim, RL Li, B Borobakas, MD Wright

Journal article  |  2001  |  Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

BAFF mediates survival of peripheral immature B lymphocytes

M Batten, J Groom, TG Cachero, F Qian, P Schneider, J Tschopp, JL Browning, F Mackay

Journal article  |  2000  |  Journal of Experimental Medicine