Nuzhat Ahmed

TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells

Ruth M Escalona, Maree Bilandzic, Patrick Western, Elif Kadife, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Journal article  |  2020  |  BMC Cancer

BACKGROUND: The metzincin family of metalloproteinases and the tissue inhibitors of metalloproteinases (TIMPs) are essential prote..

In Vitro and In Vivo Toxicity and Biodistribution of Paclitaxel-Loaded Cubosomes as a Drug Delivery Nanocarrier: A Case Study Using an A431 Skin Cancer Xenograft Model

Jiali Zhai, Fiona H Tan, Rodney B Luwor, T Srinivasa Reddy, Nuzhat Ahmed, Calum J Drummond, Nhiem Tran

Journal article  |  2020  |  ACS Applied Bio Materials

Ovarian Cancer, Cancer Stem Cells and Current Treatment Strategies: A Potential Role of Magmas in the Current Treatment Methods

Nuzhat Ahmed, Elif Kadife, Ali Raza, Mary Short, Paul T Jubinsky, George Kannourakis

Journal article  |  2020  |  Cells

Epithelial ovarian cancer (EOC) constitutes 90% of ovarian cancers (OC) and is the eighth most common cause of cancer-related deat..

Paclitaxel-Induced Src Activation Is Inhibited by Dasatinib Treatment, Independently of Cancer Stem Cell Properties, in a Mouse Model of Ovarian Cancer

Elif Kadife, Emily Chan, Rodney Luwor, George Kannourakis, Jock Findlay, Nuzhat Ahmed

Journal article  |  2019  |  Cancers

Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells

Nuzhat Ahmed, Ruth Escalona, Dilys Leung, Emily Chan, George Kannourakis

Journal article  |  2018  |  Seminars in Cancer Biology

Paclitaxel-Loaded Self-Assembled Lipid Nanoparticles as Targeted Drug Delivery Systems for the Treatment of Aggressive Ovarian Cancer

Jiali Zhai, Rodney B Luwor, Nuzhat Ahmed, Ruth Escalona, Fiona H Tan, Celesta Fong, Julian Ratcliffe, Judith A Scoble, Calum J Drummond, Nhiem Tran

Journal article  |  2018  |  ACS Applied Materials & Interfaces

Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer.

Emily Chan, Rodney Luwor, Christopher Burns, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Journal article  |  2018  |  Oncotarget

Despite a good initial response to front-line chemotherapy, majority of the ovarian cancer patients relapse with consecutive phase..

The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression

Ruth M Escalona, Emily Chan, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Journal article  |  2018  |  International Journal of Molecular Sciences

Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling

Chantel Samardzija, David W Greening, Ruth Escalona, Maoshan Chen, Maree Bilandzic, Rodney Luwor, George Kannourakis, Jock K Findlay, Nuzhat Ahmed

Journal article  |  2017  |  SCIENTIFIC REPORTS

Surface Profiling of Extracellular Vesicles from Plasma or Ascites Fluid Using DotScan Antibody Microarrays

Larissa Belov, Susannah Hallal, Kieran Matic, Jerry Zhou, Sandra Wissmueller, Nuzhat Ahmed, Sumaiya Tanjil, Stephen P Mulligan, O Giles Best, Richard J Simpson, Richard I Christopherson

Book Chapter  |  2017  |  Methods in Molecular Biology