Katie Ganio

Host-Mediated Copper Stress Is Not Protective against Streptococcus pneumoniae D39 Infection

Stephanie L Neville, Bliss A Cunningham, Eve A Maunders, Aimee Tan, Jacinta A Watts, Katherine Ganio, Bart A Eijkelkamp, Victoria G Pederick, Raquel Gonzalez de Vega, David Clases, Philip A Doble, Christopher A McDevitt

Journal article  |  2022  |  MICROBIOLOGY SPECTRUM

Metal ions are required by all organisms for the chemical processes that support life. However, in excess they can also exert toxi..

Structural and biochemical characterization of Acinetobacter baumannii ZnuA

Saleh Alquethamy, Katherine Ganio, Zhenyao Luo, Sheikh I Hossain, Andrew J Hayes, Thomas Ve, Mark R Davies, Evelyne Deplazes, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2022  |  Journal of Inorganic Biochemistry

Acinetobacter baumannii is a Gram-negative nosocomial pathogen associated with significant disease. Crucial to the survival and pa..

The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis

Eve A Maunders, Dalton HY Ngu, Katherine Ganio, Sheikh I Hossain, Bryan YJ Lim, Michael G Leeming, Zhenyao Luo, Aimee Tan, Evelyne Deplazes, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2022  |  FRONTIERS IN MICROBIOLOGY

Acquisition of the trace-element molybdenum via the high-affinity ATP-binding cassette permease ModABC is essential for Pseudomona..

Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations

Mark A Greenough, Darius JR Lane, Rachelle Balez, Helena Targa Dias Anastacio, Zhiwen Zeng, Katherine Ganio, Christopher A McDevitt, Karla Acevedo, Abdel Ali Belaidi, Jari Koistinaho, Lezanne Ooi, Scott Ayton, Ashley Bush

Journal article  |  2022  |  CELL DEATH AND DIFFERENTIATION

Mutations in presenilin 1 and 2 (PS1 and PS2) cause autosomal dominant familial Alzheimer's disease (FAD). Ferroptosis has been im..

Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging

Odette Leiter, Zhan Zhuo, Ruslan Rust, Joanna M Wasielewska, Lisa Groennert, Susann Kowal, Rupert W Overall, Vijay S Adusumilli, Daniel G Blackmore, Adam Southon, Katherine Ganio, Christopher A McDevitt, Nicole Rund, David Brici, Imesh Aththanayake Mudiyan, Alexander M Sykes, Annette E Ruenker, Sara Zocher, Scott Ayton, Ashley Bush, et al.

Journal article  |  2022  |  CELL METABOLISM

Although the neurogenesis-enhancing effects of exercise have been extensively studied, the molecular mechanisms underlying this re..

The Role of ZntA in Klebsiella pneumoniae Zinc Homeostasis

Eve A Maunders, Katherine Ganio, Andrew J Hayes, Stephanie L Neville, Mark R Davies, Richard A Strugnell, Christopher A McDevitt, Aimee Tan

Journal article  |  2022  |  MICROBIOLOGY SPECTRUM

Klebsiella pneumoniae is an opportunistic Gram-negative pathogen that is a leading cause of healthcare-associated infections, incl..

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Erin B Brazel, Aimee Tan, Stephanie L Neville, Amy R Iverson, Saumya R Udagedara, Bliss A Cunningham, Mwilye Sikanyika, David MP De Oliveira, Bernhard Keller, Lisa Bohlmann, Ibrahim M El-Deeb, Katherine Ganio, Bart A Eijkelkamp, Alastair G McEwan, Mark von Itzstein, Megan J Maher, Mark J Walker, Jason W Rosch, Christopher A McDevitt

Journal article  |  2022  |  CELL REPORTS

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-res..

Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain

Shene Yi-Shiuan Chiou, Kai Kysenius, Yifan Huang, Mark David Habgood, Liam M Koehn, Fiona Qiu, Peter J Crouch, Swati Varshney, Katherine Ganio, Katarzyna Magdalena Dziegielewska, Norman Ruthven Saunders

Journal article  |  2021  |  FLUIDS AND BARRIERS OF THE CNS

BACKGROUND: Little is known about the extent of drug entry into developing brain, when administered to pregnant and lactating wome..

The Molecular Basis of Acinetobacter baumannii Cadmium Toxicity and Resistance

Saleh F Alquethamy, Felise G Adams, Ram Maharjan, Natasha N Delgado, Maoge Zang, Katherine Ganio, James C Paton, Karl A Hassan, Ian T Paulsen, Christopher A McDevitt, Amy K Cain, Bart A Eijkelkamp

Journal article  |  2021  |  APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, in soil, and as commensals of the human sk..

Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae

Marina L Zupan, Zhenyao Luo, Katherine Ganio, Victoria G Pederick, Stephanie L Neville, Evelyne Deplazes, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2021  |  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Streptococcus pneumoniae scavenges essential zinc ions from the host during colonization and infection. This is achieved by the AT..