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Richard Hughes' selected work
Design And Synthesis Of Tricyclic Dimer Peptide Mimetics Of Bdnf As Potential Remyelinatin..
Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in ..
The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP..
Towards New Drugs For Multiple Sclerosis: Synthetic Strategies For The Synthesis Of Novel ..
Displaying the 15 most recent projects by Richard Hughes.
Displaying the 37 most recent scholarly works by Richard Hughes.
Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain
Jessica L Fletcher, Rhiannon J Wood, Jacqueline Nguyen, Eleanor ML Norman, Christine MK Jun, Alexa R Prawdiuk, Melissa Biemond, Huynh TH Nguyen, Susan E Northfield, Richard A Hughes, David G Gonsalvez, Junhua Xiao, Simon S Murray
Journal article | 2018 | The Journal of Neuroscience
A Brain-Derived Neurotrophic Factor-Based p75(NTR) Peptide Mimetic Ameliorates Experimental Autoimmune Neuritis Induced Axonal Pathology and Demyelination
David G Gonsalvez, Giang Tran, Jessica L Fletcher, Richard A Hughes, Suzanne Hodgkinson, Rhiannon J Wood, Sang Won Yoo, Mithraka De Silva, Wong W Agnes, Catriona McLean, Paul Kennedy, Trevor J Kilpatrick, Simon S Murray, Junhua Xiao
Journal article | 2017 | ENEURO
The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity
Nitin A Patil, Ross AD Bathgate, Martina Kocan, Sheng Yu Ang, Julien Tailhades, Frances Separovic, Roger Summers, Johannes Grosse, Richard A Hughes, John D Wade, Mohammed Akhter Hossain
Journal article | 2016 | Amino Acids
Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist
Nitin A Patil, Richard A Hughes, K Johan Rosengren, Martina Kocan, Sheng Yu Ang, Julien Tailhades, Frances Separovic, Roger J Summers, Johannes Grosse, John D Wade, Ross AD Bathgate, Mohammed Akhter Hossain
Journal article | 2016 | Journal of Medicinal Chemistry
The structural determinants of insulin-like Peptide 3 activity.
Ross AD Bathgate, Soude Zhang, Richard A Hughes, K Johan Rosengren, John D Wade
Journal article | 2012 | Frontiers in Endocrinology
Insulin-like peptide 3 (INSL3) is a hormone and/or paracrine factor which is a member of the relaxin peptide family. It has key ro..
Design and Development of Analogues of Dimers of Insulin-like Peptide 3 B-Chain as High-Affinity Antagonists of the RXFP2 Receptor
Fazel Shabanpoor, Suode Zhang, Richard A Hughes, Mohammed Akhter Hossain, Sharon Layfield, Tania Ferraro, Ross AD Bathgate, Frances Separovic, John D Wade
Journal article | 2011 | Biopolymers
Synthesis of "Difficult" Fluorescence Quenched Substrates of Granzyme C
Susan E Northfield, Kade D Roberts, Simon J Mountford, Richard A Hughes, Dion Kaiserman, Matthew Mangan, Robert N Pike, Phillip I Bird, Philip E Thompson
Journal article | 2010 | International Journal of Peptide Research and Therapeutics
Effect of helix-promoting strategies on the biological activity of novel analogues of the B-chain of INSL3
Fazel Shabanpoor, Richard A Hughes, Suode Zhang, Ross AD Bathgate, Sharon Layfield, Mohammed Akhter Hossain, Geoffrey W Tregear, Frances Separovic, John D Wade
Journal article | 2010 | Amino Acids
Brain-derived neurotrophic factor regulates early postnatal developmental cell death of dopamine neurons of the substantia nigra in vivo
Tinmarla F Oo, Deanna M Marchionini, Olga Yarygina, Paul D O'Leary, Richard A Hughes, Nikolai Kholodilov, Robert E Burke
Journal article | 2009 | Molecular and Cellular Neurosciences
Solid-phase synthesis of europium-labeled human INSL3 as a novel probe for the study of ligand-receptor interactions
Fazel Shabanpoor, Richard A Hughes, Ross AD Bathgate, Suode Zhang, Denis B Scanlon, Feng Lin, Mohammed Akhter Hossain, Frances Separovic, John D Wade
Journal article | 2008 | Bioconjugate Chemistry
Molecular pathways for lymphangiogenesis and their role in human disease.
Steven A Stacker, Rae H Farnsworth, Tara Karnezis, Ramin Shayan, Darrin P Smith, Karri Paavonen, Natalia Davydova, Carol Caesar, Rachael Inder, Megan E Baldwin, Bradley K McColl, Sally Roufail, Richard A Williams, Richard A Hughes, Kari Alitalo, Marc G Achen
Conference Proceedings | 2007 | Decoding the genomic control of immune reactions
The lymphatic network functions to return fluid, cells and macromolecules to the circulation. Recent characterization of growth fa..
2-methoxyestradiol and analogs as novel antiproliferative agents: Analysis of three-dimensional quantitative structure-activity relationships for DNA synthesis inhibition and estrogen receptor binding
RA Hughes, T Harris, E Altmann, D McAllister, R Vlahos, A Robertson, M Cushman, ZQ Wang, AG Stewart
Journal article | 2002 | Molecular Pharmacology
Honours, Awards and Fellowships
Pharmacology And Therapeutics
Australian Peptide Society
Doctor of Philosophy
University of London
Master of Pharmacy
Victorian College of Pharmacology