Jessica Howell

Assessment of a primary care e-support package of automated case finding, simplified treatment algorithm and decision support to increase hepatitis B treatment uptake in primary care clinics in Australia (SIMPLY-B Study): protocol for a pilot evaluation.

Dina Moussa, Jack Wallace, Jo-Anne Manski-Nankervis, Joseph S Doyle, Long Nguyen, Douglas Boyle, Mark A Stoové, Jason Asselin, Zina Valaydon, Marvad Ahad, Susanne Glasgow, Kate New, Jane S Hocking, Lena Sanci, Alexander Thompson, Margaret Hellard, Jess Howell

Journal article  |  2023  |  BMJ Open

INTRODUCTION: Despite the availability of effective, subsidised hepatitis B treatment, linkage to care and treatment rates remain ..

Validation of a novel point-of-care test for alanine aminotransferase measurement: A pilot cohort study

Jessica Howell, Huy Van, Minh D Pham, Rohit Sawhney, Fan Li, Purnima Bhat, John Lubel, William Kemp, Stephen Bloom, Avik Majumdar, Geoffrey W McCaughan, Samuel Hall, Timothy Spelman, Joseph S Doyle, Margaret Hellard, Kumar Visvanathan, Alexander Thompson, Heidi E Drummer, David Anderson

Journal article  |  2023  |  LIVER INTERNATIONAL

BACKGROUND: Alanine aminotransferase (ALT) measurement is essential for evaluation of liver disease. We validated a novel rapid po..

The cost-effectiveness of universal hepatitis B screening for reaching WHO diagnosis targets in Australia by 2030

Yinzong Xiao, Margaret E Hellard, Alexander J Thompson, Christopher Seaman, Jess Howell, Nick Scott

Journal article  |  2023  |  MEDICAL JOURNAL OF AUSTRALIA

OBJECTIVES: To assess the impact on diagnosis targets, cost, and cost-effectiveness of universal hepatitis B screening in Australi..

Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL -mediated Necroptosis From Contributing to Liver Pathologies

Simon P Preston, Michael D Stutz, Cody C Allison, Ueli Nachbur, Quentin Gouil, Manh Tran Bang, Valerie Duvivier, Philip Arandjelovic, James P Cooney, Liana Mackiewicz, Yanxiang Meng, Jan Schaefer, Stefanie M Bader, Hongke Peng, Zina Valaydon, Pravin Rajasekaran, Charlie Jennison, Sash Lopaticki, Ann Farrell, Marno Ryan, et al.

Journal article  |  2022  |  GASTROENTEROLOGY

BACKGROUND & AIMS: Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury incl..

Exploring the Public Health and Social Implications of Future Curative Hepatitis B Interventions

Jack Wallace, Jacqueline Richmond, Jessica Howell, Behzad Hajarizadeh, Jennifer Power, Carla Treloar, Peter A Revill, Benjamin Cowie, Su Wang, Mark Stoove, Alisa Pedrana, Margaret Hellard

Journal article  |  2022  |  VIRUSES-BASEL

Hepatitis B is a significant global health issue where the 296 million people estimated to live with the infection risk liver dise..

Validation of novel point-of-care test for alanine aminotransferase measurement: A pilot cohort study.

Jessica Howell, Huy Van, Minh Pham, Rohit Sawhney, Fan Li, Purnima Bhat, John Lubel, William Kemp, Stephen Bloom, Avik Majumdar, Geoff McCaughan, Samuel Hall, Timothy Spelman, Joseph S Doyle, Margaret Hellard, Kumar Visvanathan, Alexander J Thompson, Heidi E Drummer, David Anderson

Journal article  |  2022  |  Clin Liver Dis (Hoboken)

HBV continuum of care using community- and hospital-based screening interventions in Senegal: Results from the PROLIFICA programme.

Amina Sow, Maud Lemoine, Papa Souleymane Toure, Madoky Diop, Gora Lo, Jean De Veiga, Omar Thiaw Pape, Khady Seck, Gibril Ndow, Lamin Bojang, Arame Kane, Marina Oudiane, Jess Howell, Shevanthi Nayagam, Jude Moutchia, Isabelle Chemin, Maimuna Mendy, Coumba Toure-Kane, Mark Thursz, Mourtalla Ka, et al.

Journal article  |  2022  |  JHEP Rep

BACKGROUND & AIMS: Strategies to implement HBV screening and treatment are critical to achieve HBV elimination but have been inade..

Making child's play of tolerance: Defining the immune-viral interplay during combination entecavir and pegylated interferon therapy for immune-tolerant hepatitis B infection.

Jessica Howell, Margaret Hellard

Journal article  |  2022  |  Hepatology

Lenvatinib for the treatment of hepatocellular carcinoma-a real-world multicenter Australian cohort study

Kurvi Patwala, David Stephen Prince, Yael Celermajer, Waafiqa Alam, Eldho Paul, Simone Irene Strasser, Geoffrey William McCaughan, Paul Gow, Siddharth Sood, Elise Murphy, Stuart Roberts, Elliot Freeman, Elizabeth Stratton, Scott Anthony Davison, Miriam Tania Levy, Mccawley Clark-Dickson, Nguyen Vi, Sally Bell, Amanda Nicoll, Ashley Bloom, et al.

Journal article  |  2022  |  HEPATOLOGY INTERNATIONAL

INTRODUCTION: Hepatocellular carcinoma (HCC) is a serious complication of chronic liver disease. Lenvatinib is an oral multikinase..

Bridging the gap to achieve viral hepatitis mortality targets

Ericka Flores, Jessica Howell

Journal article  |  2022  |  LANCET GASTROENTEROLOGY & HEPATOLOGY