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Organ-specific isoform selection of fatty acid-binding proteins in tissue-resident lymphoc..
Displaying the 18 most recent projects by Francis Carbone.
Displaying the 217 most recent scholarly works by Francis Carbone.
Organ-specific isoform selection of fatty acid-binding proteins in tissue-resident lymphocytes.
H Frizzell, R Fonseca, SN Christo, M Evrard, S Cruz-Gomez, NG Zanluqui, B von Scheidt, D Freestone, SL Park, HEG McWilliam, JA Villadangos, FR Carbone, LK Mackay
Journal article | 2020 | Science Immunology
Tissue-resident memory T (TRM) cells exist throughout the body, where they are poised to mediate local immune responses. Although ..
Staged development of long-lived T-cell receptor alpha beta T(H)17 resident memory T-cell population to Candida albicans after skin infection
Chang Ook Park, Xiujun Fu, Xiaodong Jiang, Youdong Pan, Jessica E Teague, Nicholas Collins, Tian Tian, John T O'Malley, Ryan O Emerson, Ji Hye Kim, Yookyung Jung, Rei Watanabe, Robert C Fuhlbrigge, Francis R Carbone, Thomas Gebhardt, Rachael A Clark, Charles P Lin, Thomas S Kupper
Journal article | 2018 | Journal of Allergy and Clinical Immunology
Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses
Simone L Park, Ali Zaid, Jyh Liang Hor, Susan N Christo, Julia E Prier, Brooke Davies, Yannick O Alexandre, Julia L Gregory, Tiffany A Russell, Thomas Gebhardt, Francis R Carbone, David C Tscharke, William R Heath, Scott N Mueller, Laura K Mackay
Journal article | 2018 | Nature Immunology
Development of a Novel CD4( ) TCR Transgenic Line That Reveals a Dominant Role for CD8( ) Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria
Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M Jones, Wei Yi Ng, Gayle M Davey, Dorothee Berthold, Lauren Holz, Yu Kato, Matthias H Enders, Ganchimeg Bayarsaikhan, Sanne H Hendriks, Lianne IM Lansink, Jessica A Engel, Megan SF Soon, Kylie R James, Anton Cozijnsen, Vanessa Mollard, Alessandro D Uboldi, Christopher J Tonkin, et al.
Journal article | 2017 | The Journal of Immunology
Liver-Resident Memory CD8( ) T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection
Daniel Fernandez-Ruiz, Wei Yi Ng, Lauren E Holz, Joel Z Ma, Ali Zaid, Yik Chun Wong, Lei Shong Lau, Vanessa Mollard, Anton Cozijnsen, Nicholas Collins, Jessica Li, Gayle M Davey, Yu Kato, Sapna Devi, Roghieh Skandari, Michael Pauley, Jonathan H Manton, Dale I Godfrey, Asolina Braun, Szun Szun Tay, et al.
Journal article | 2016 | Immunity
Skin CD4( ) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation
Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R Heath, Scott N Mueller, Thomas S Kupper, Thomas Gebhardt, Francis R Carbone
Journal article | 2016 | NATURE COMMUNICATIONS
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes
Laura K Mackay, Martina Minnich, Natasja AM Kragten, Yang Liao, Benjamin Nota, Cyril Seillet, Ali Zaid, Kevin Man, Simon Preston, David Freestone, Asolina Braun, Erica Wynne-Jones, Felix M Behr, Regina Stark, Daniel G Pellicci, Dale I Godfrey, Gabrielle T Belz, Marc Pellegrini, Thomas Gebhardt, Meinrad Busslinger, et al.
Journal article | 2016 | Science
T-box Transcription Factors Combine with the Cytokines TGF-beta and IL-15 to Control Tissue-Resident Memory T Cell Fate
Laura K Mackay, Erica Wynne-Jones, David Freestone, Daniel G Pellicci, Lisa A Mielke, Dane M Newman, Asolina Braun, Frederick Masson, Axel Kallies, Gabrielle T Belz, Francis R Carbone
Journal article | 2015 | Immunity
Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention
Laura K Mackay, Asolina Braun, Bethany L Macleod, Nicholas Collins, Christina Tebartz, Sammy Bedoui, Francis R Carbone, Thomas Gebhardt
Journal article | 2015 | The Journal of Immunology
CD8( ) T Cells from a Novel T Cell Receptor Transgenic Mouse Induce Liver-Stage Immunity That Can Be Boosted by Blood-Stage Infection in Rodent Malaria
Lei Shong Lau, Daniel Fernandez-Ruiz, Vanessa Mollard, Angelika Sturm, Michelle A Neller, Anton Cozijnsen, Julia L Gregory, Gayle M Davey, Claerwen M Jones, Yi-Hsuan Lin, Ashraful Haque, Christian R Engwerda, Catherine Q Nie, Diana S Hansen, Kenneth M Murphy, Anthony T Papenfuss, John J Miles, Scott R Burrows, Tania de Koning-Ward, Geoffrey I McFadden, et al.
Journal article | 2014 | PLOS PATHOGENS
Persistence of skin-resident memory T cells within an epidermal niche
Ali Zaid, Laura K Mackay, Azad Rahimpour, Asolina Braun, Marc Veldhoen, Francis R Carbone, Jonathan H Manton, William R Heath, Scott N Mueller
Journal article | 2014 | Proceedings of the National Academy of Sciences of the United States of America
The developmental pathway for CD103( )CD8( ) tissue-resident memory T cells of skin
Laura K Mackay, Azad Rahimpour, Joel Z Ma, Nicholas Collins, Angus T Stock, Ming-Li Hafon, Javier Vega-Ramos, Pilar Lauzurica, Scott N Mueller, Tijana Stefanovic, David C Tscharke, William R Heath, Michael Inouye, Francis R Carbone, Thomas Gebhardt
Journal article | 2013 | Nature Immunology
Long-lived epithelial immunity by tissue-resident memory T (T-RM) cells in the absence of persisting local antigen presentation
Laura K Mackay, Angus T Stock, Joel Z Ma, Claerwen M Jones, Stephen J Kent, Scott N Mueller, William R Heath, Francis R Carbone, Thomas Gebhardt
Journal article | 2012 | Proceedings of the National Academy of Sciences of the United States of America
Maintenance of T Cell Function in the Face of Chronic Antigen Stimulation and Repeated Reactivation for a Latent Virus Infection
Laura K Mackay, Linda Wakim, Catherine J van Vliet, Claerwen M Jones, Scott N Mueller, Oliver Bannard, Douglas T Fearon, William R Heath, Francis R Carbone
Journal article | 2012 | Journal of Immunology
Blood-Stage Plasmodium berghei Infection Generates a Potent, Specific CD8( ) T-Cell Response Despite Residence Largely in Cells Lacking MHC I Processing Machinery
Lei Shong Lau, Daniel Fernandez Ruiz, Gayle M Davey, Tania F de Koning-Ward, Anthony T Papenfuss, Francis R Carbone, Andrew G Brooks, Brendan S Crabb, William R Heath
Journal article | 2011 | Journal of Infectious Diseases
Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance
Francois-Xavier Hubert, Sarah A Kinkel, Gayle M Davey, Belinda Phipson, Scott N Mueller, Adrian Liston, Anna I Proietto, Ping ZF Cannon, Simon Forehan, Gordon K Smyth, Li Wu, Christopher C Goodnow, Francis R Carbone, Hamish S Scott, William R Heath
Journal article | 2011 | Blood
Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8( ) T cells
Sophie A Valkenburg, E Bridie Day, Natasha G Swan, Hayley A Croom, Francis R Carbone, Peter C Doherty, Stephen J Turner, Katherine Kedzierska
Journal article | 2010 | European Journal of Immunology
Cross-presentation of viral and self antigens by skin-derived CD103( ) dendritic cells
Sammy Bedoui, Paul G Whitney, Jason Waithman, Liv Eidsmo, Linda Wakim, Irina Caminschi, Rhys S Allan, Magdalena Wojtasiak, Ken Shortman, Francis R Carbone, Andrew G Brooks, William R Heath
Journal article | 2009 | Nature Immunology
Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance
Ian A Parish, Jason Waithman, Gayle M Davey, Gabrielle T Belz, Justine D Mintern, Christian Kurts, Robyn M Sutherland, Francis R Carbone, William R Heath
Journal article | 2009 | Proceedings of the National Academy of Sciences of the United States of America
Blood-stage Plasmodium infection induces CD8( ) T lymphocytes to parasite-expressed antigens, largely regulated by CD8 alpha( ) dendritic cells
Rachel J Lundie, Tania F de Koning-Ward, Gayle M Davey, Catherine Q Nie, Diana S Hansen, Lei Shong Lau, Justine D Mintern, Gabrielle T Belz, Louis Schofield, Francis R Carbone, Jose A Villadangos, Brendan S Crabb, William R Heath
Journal article | 2008 | Proceedings of the National Academy of Sciences of the United States of America
Induction of antigen-specific T cell responses following blood-stage Plasmodium infection occurs mainly via CD8 alpha dendritic cells but is short-lived.
Rachel J Lundie, Tania F de Koning-Ward, Gayle M Davey, Catherine Q Nie, Diana S Hansen, Louis Schofield, Gabrielle T Belz, Francis R Carbone, Jose A Villadangos, Brendan S Crabb, William R Heath
Conference Proceedings | 2008 | INTERNATIONAL JOURNAL FOR PARASITOLOGY
Skin-derived dendritic cells can mediate deletional tolerance of class I-Restricted self-reactive T cells
Jason Waithman, Rhys S Allan, Hiroshi Kosaka, Hiroaki Azukizawa, Ken Shortman, Manfred B Lutz, William R Heath, Francis R Carbone, Gabrielle T Belz
Journal article | 2007 | Journal of Immunology
A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection
Daniel P Barr, Gabrielle T Belz, Patrick C Reading, Magdalena Wojtasiak, Paul G Whitney, William R Heath, Francis R Carbone, Andrew G Brooks
Journal article | 2007 | European Journal of Immunology
The dominant role of CD8( ) dendritic cells in cross-presentation is not dictated by antigen capture
Petra Schnorrer, Georg MN Behrens, Nicholas S Wilson, Joanne L Pooley, Christopher M Smith, Dima EI-Sukkari, Gayle Davey, Fiona Kupresanin, Ming Li, Eugene Maraskovsky, Gabrielle T Belz, Francis R Carbone, Ken Shortman, William R Heath, Jose A Villadangos
Journal article | 2006 | Proceedings of the National Academy of Sciences of the United States of America
Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming
Rhys S Allan, Jason Waithman, Sammy Bedoui, Claerwen M Jones, Jose A Villadangos, Yifan Zhan, Andrew M Lew, Ken Shortman, William R Heath, Francis R Carbone
Journal article | 2006 | Immunity
Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity
NS Wilson, GMN Behrens, RJ Lundie, CM Smith, J Waithman, L Young, SP Forehan, A Mount, RJ Steptoe, KD Shortman, TF de Koning-Ward, GT Belz, FR Carbone, BS Crabb, WR Heath, JA Villadangos
Journal article | 2006 | NATURE IMMUNOLOGY
Erratum: The structure of H-2Kb and Kbm8 complexed to a herpes simplex virus determinant: Evidence for a conformational switch that governs T cell repertoire selection and viral resistance (Journal of Immunology (2004) 173 (402-409))
AI Webb, NA Borg, MA Dunstone, L Kjer-Nielsen, T Beddoe, J McCluskey, FR Carbone, SP Bottomley, MI Aguilar, AW Purcell, J Rossjohn
Journal article | 2004 | Journal of Immunology
The structure of H-2K(b) and K-bm8 complexed to a herpes simplex virus determinant: Evidence for a conformational switch that governs T cell repertoire selection and viral resistance
AI Webb, NA Borg, MA Dunstone, L Kjer-Nielsen, T Beddoe, J McCluskey, FR Carbone, SP Bottomley, MI Aguilar, AW Purcell, J Rossjohn
Journal article | 2004 | Journal of Immunology
Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus
GT Belz, CM Smith, L Kleinert, P Reading, A Brooks, K Shortman, FR Carbone, WR Heath
Journal article | 2004 | Proceedings of the National Academy of Sciences of the United States of America
Rapid cytotoxic T lymphocyte activation occurs in the draining lymph nodes after cutaneous herpes simplex virus infection as a result of early antigen presentation and not the presence of virus
SN Mueller, CM Jones, CM Smith, WR Heath, FR Carbone
Journal article | 2002 | JOURNAL OF EXPERIMENTAL MEDICINE
Junctional biases in the naive TCR repertoire control the CTL response to an immunodominant determinant of HSV-1
ME Wallace, M Bryden, SC Cose, RM Coles, TN Schumacher, A Brooks, FR Carbone
Journal article | 2000 | Immunity
The enormous diversity of the T cell pool makes it difficult to determine whether inherent biases in the naive TCR repertoire can ..
T-cell receptor contact and MHC binding residues of a major rye grass pollen allergen T-cell epitope.
MD Burton, B Blaher, C Suphioglu, RE O'Hehir, FR Carbone, JM Rolland
Journal article | 1999 | Journal of Allergy and Clinical Immunology
BACKGROUND: T cells are pivotal in the elicitation of allergic diseases. Analogues of T-cell epitope peptides with a modification ..
T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs.
SH Stotz, L Bolliger, FR Carbone, E Palmer
Journal article | 1999 | Journal of Experimental Medicine
Antagonist peptides inhibit T cell responses by an unknown mechanism. By coexpressing two independent T cell receptors (TCRs) on a..
A dominant V beta bias in the CTL response after HSV-1 infection is determined by peptide residues predicted to also interact with the TCR beta-chain CDR3.
SJ Turner, FR Carbone
Journal article | 1998 | Molecular Immunology
Many T cell responses are dominated by restricted TCR expression and can range from repeated usage of particular TCR Vbeta- and/or..
Cross-presentation of self antigens to CD8 T cells: the balance between tolerance and autoimmunity.
C Kurts, WR Heath, FR Carbone, H Kosaka, JF Miller
Journal article | 1998 | Novartis Foundation symposium
Upon encounter with foreign antigen, tissue-associated antigen-presenting cells (APCs) migrate to draining lymph nodes to prime sp..
Evidence for cooperation between TCR V region and junctional sequences in determining a dominant cytotoxic T lymphocyte response to herpes simplex virus glycoprotein B.
CM Jones, SC Cose, FR Carbone
Journal article | 1997 | International Immunology
TCR repertoire availability has the potential to influence the immune response to foreign antigens. Here we have analysed how chan..
Functional mapping of the orientation for TCR recognition of an H2-Kb-restricted ovalbumin peptide suggests that the beta-chain subunit can dominate the determination of peptide side chain specificity.
SJ Turner, SC Jameson, FR Carbone
Journal article | 1997 | Journal of Immunology
T cells recognize a complex of antigenic peptide bound to the class I or class II products of the MHC. Crystallographic analysis o..
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes.
KC Garcia, CA Scott, A Brunmark, FR Carbone, PA Peterson, IA Wilson, L Teyton
Journal article | 1996 | Nature
T-cell antigen receptors (TCR) generally interact with moderate affinity with the complex formed by major histocompatibility compl..
TCR alpha-chain usage can determine antigen-selected TCR beta-chain repertoire diversity.
SJ Turner, SC Cose, FR Carbone
Journal article | 1996 | Journal of Immunology
There is considerable variation in the TCR repertoire diversity selected by different peptide Ags. Certain responses show limited ..
Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules.
CA Scott, KC Garcia, FR Carbone, IA Wilson, L Teyton
Journal article | 1996 | The Journal of Experimental Medicine
Structural studies of cellular receptor molecules involved in immune recognition require the production of large quantities of the..
Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias.
SC Cose, JM Kelly, FR Carbone
Journal article | 1995 | Journal of Virology
The glycoprotein B (gB) from herpes simplex virus type I is a major target of cytotoxic T lymphocytes (CTL) in C57BL/6 mice. The m..
Intermediate steps in positive selection: differentiation of CD4 8int TCRint thymocytes into CD4-8 TCRhi thymocytes.
K Lundberg, W Heath, F Köntgen, FR Carbone, K Shortman
Journal article | 1995 | The Journal of Experimental Medicine
The differentiation potential of putative intermediates between CD4+8+ thymocytes and mature T cells has been examined. Such inter..
Contrast between class I and class II MHC-mediated differentiation of a CD4 CD8 T cell line: implications for lineage commitment.
J DeKoning, FR Carbone, J Kaye
Journal article | 1995 | International Immunology
Experiments in transgenic mice have demonstrated that thymocyte differentiation into the mature CD4+ helper or CD8+ cytotoxic T ce..
T cell receptor V alpha bias can be determined by TCR-contact residues within an MHC-bound peptide.
SJ Sterry, JM Kelly, SJ Turner, FR Carbone
Journal article | 1995 | Immunology and Cell Biology
Many antigen-specific T cell responses show profound V-region biases in one or both chains of the TCR alpha beta heterodimer. We h..
Circulating insulin-like growth factors-I and -II and substrates in fetal sheep following restriction of placental growth.
JA Owens, KL Kind, F Carbone, JS Robinson, PC Owens
Journal article | 1994 | Journal of Endocrinology
To determine the relationship between placental delivery of oxygen and glucose, circulating insulin-like growth factors (IGFs) and..
Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant.
JM Kelly, SJ Sterry, S Cose, SJ Turner, J Fecondo, S Rodda, PJ Fink, FR Carbone
Journal article | 1993 | European Journal of Immunology
We have analyzed the T cell receptor (TCR) repertoire found in the major histocompatibility complex class I-restricted cytotoxic T..
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells.
SC Jameson, FR Carbone, MJ Bevan
Journal article | 1993 | The Journal of Experimental Medicine
A previous report showed that the proliferative response of helper T cells to class II major histocompatibility complex (MHC)-rest..
CHANGES AT PEPTIDE RESIDUES BURIED IN THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS-I BINDING CLEFT INFLUENCE T-CELL RECOGNITION - A POSSIBLE ROLE FOR INDIRECT CONFORMATIONAL ALTERATIONS IN THE MHC CLASS-I OR BOUND PEPTIDE IN DETERMINING T-CELL RECOGNITION
W CHEN, J MCCLUSKEY, S RODDA, FR CARBONE
Journal article | 1993 | JOURNAL OF EXPERIMENTAL MEDICINE
Both intrathymic and peripheral selection modulate the differential expression of V beta 5 among CD4 and CD8 T cells.
PJ Fink, K Swan, G Turk, MW Moore, FR Carbone
Journal article | 1992 | The Journal of Experimental Medicine
Murine T cells expressing V beta 5 are characterized by (a) intrathymic deletion in the presence of I-E and products of endogenous..
Induction of antigen-specific class I-restricted cytotoxic T cells by soluble proteins in vivo.
S Raychaudhuri, M Tonks, F Carbone, T Ryskamp, WJ Morrow, N Hanna
Journal article | 1992 | Proceedings of the National Academy of Sciences
Cytotoxic T lymphocytes (CTL) are induced specifically against viral and tumor antigens presented by major histocompatibility comp..
T cell receptor alpha-chain pairing determines the specificity of residue 262 within the Kb-restricted, ovalbumin257-264 determinant.
FR Carbone, SJ Sterry, J Butler, S Rodda, MW Moore
Journal article | 1992 | International Immunology
Ovalbumin-specific, Kb-restricted T cells recognize the minimal fully active synthetic peptide ovalbumin (OVA)257-264. This sequen..
Murine AIDS superantigen reactivity of the T cells bearing V beta 5 T cell antigen receptor.
O Kanagawa, BA Nussrallah, ME Wiebenga, KM Murphy, HC Morse, FR Carbone
Journal article | 1992 | Journal of Immunology
A B cell line, B6-1710, that expresses the defective virus known to induce murine AIDS stimulates a large fraction of nonprimed sp..
Conformational difference of T cell antigen receptors revealed by monoclonal antibodies to mouse V beta 5 T cell receptor for antigen determinants.
O Kanagawa, Y Utsunomiya, J Bill, E Palmer, MW Moore, FR Carbone
Journal article | 1991 | Journal of Immunology
The mAb MR9-4 and MR9-8 react with T cells expressing the V beta 5.1 and -5.2 chains of the TCR. T cells expressing V beta 5.1 TCR..
pH sensitive liposomes provide an efficient means of sensitizing target cells to class I restricted CTL recognition of a soluble protein.
R Reddy, F Zhou, L Huang, F Carbone, M Bevan, BT Rouse
Journal article | 1991 | Journal of Immunological Methods
Exogenous antigens are normally endocytosed and enter the class II pathway of processing and presentation. It had been shown earli..
The effect of mutations in the MHC class I peptide binding groove on the cytotoxic T lymphocyte recognition of the Kb-restricted ovalbumin determinant.
J Nikolić-Zugić, FR Carbone
Journal article | 1990 | European Journal of Immunology
The H-2Kb-restricted cytotoxic T lymphocyte (CTL) response directed against ovalbumin (OVA) is specific for a region contained wit..
Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo.
FR Carbone, MJ Bevan
Journal article | 1990 | The Journal of Experimental Medicine
MHC class I-restricted T lymphocyte responses are usually directed to cellular antigenic components resulting from endogenous gene..
Class I-restricted presentation occurs without internalization or processing of exogenous antigenic peptides.
NA Hosken, MJ Bevan, FR Carbone
Journal article | 1989 | Journal of Immunology
Previous studies have shown that glutaraldehyde-fixed cells can present fragmented, but not native, Ag to class II-restricted T ce..
The activation of pigeon cytochrome c-specific T cell hybridomas by antigenic peptides is influenced by non-native sequences at the amino terminus of the determinant.
H Bhayani, FR Carbone, Y Paterson
Journal article | 1988 | Journal of Immunology
We recently demonstrated that the sequence 95-104 contains all the residues necessary for direct recognition of the I-Ek restricte..
Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides.
FR Carbone, MW Moore, JM Sheil, MJ Bevan
Journal article | 1988 | The Journal of Experimental Medicine
Antigen-specific cytotoxic T cells can be generated by primary in vitro stimulation of spleen cells from C57BL/6 mice with appropr..
Processing of a minimal antigenic peptide alters its interaction with MHC molecules.
BS Fox, FR Carbone, RN Germain, Y Paterson, RH Schwartz
Journal article | 1988 | Nature
Before their recognition by T lymphocytes, protein antigens generally require processing by antigen-presenting cells. In a poorly ..
Effects of protein restriction, melatonin administration, and short daylength on brain benzodiazepine receptors in prepubertal male rats.
DJ Kennaway, P Royles, H Webb, F Carbone
Journal article | 1988 | Journal of Pineal Research
The possibility that there are changes in brain benzodiazepine binding sites controlled by photoperiod was investigated in two str..
Structure-activity studies of melatonin analogues in prepubertal male rats.
DJ Kennaway, HM Hugel, S Clarke, A Tjandra, DW Johnson, P Royles, HA Webb, F Carbone
Journal article | 1988 | Australian Journal of Biological Sciences
Comparison has been made between the activity of the pineal hormone melatonin, and several analogues and metabolites in inhibiting..
Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease.
MF Kagnoff, YJ Paterson, PJ Kumar, DD Kasarda, FR Carbone, DJ Unsworth, RK Austin
Journal article | 1987 | Gut
We previously noted a region of amino acid sequence homology between A-gliadin, a major alpha-gliadin component known to activate ..
A new T helper cell specificity within the pigeon cytochrome c determinant 95-104.
FR Carbone, UD Staerz, Y Paterson
Journal article | 1987 | European Journal of Immunology
A T cell hybridoma with unusual antigen specificity has been isolated from B10.BR mice immunized with pigeon cytochrome c. Using s..
The use of hydrophobic, alpha-helix-defined peptides in delineating the T cell determinant for pigeon cytochrome c.
FR Carbone, BS Fox, RH Schwartz, Y Paterson
Journal article | 1987 | Journal of Immunology
The B10.A T cell proliferative response to pigeon cytochrome c is largely directed to a single site in the molecule located at the..
Phase delay of the rhythm of 6-sulphatoxy melatonin excretion by artificial light.
DJ Kennaway, CR Earl, PF Shaw, P Royles, F Carbone, H Webb
Journal article | 1987 | Journal of Pineal Research
The purpose of this study was to investigate the effect of bright artificial light exposure on the rhythms of 6-sulphatoxy melaton..
Monoclonal antibodies to horse cytochrome c expressing four distinct idiotypes distribute among two sites on the native protein.
FR Carbone, Y Paterson
Journal article | 1985 | Journal of Immunology
Antibody-secreting hybridoma cell lines produced from BALB/c mice that had been immunized with horse cytochrome c (cyt c) conjugat..
2 LARGE IMMUNOGENIC AND ANTIGENIC MYOGLOBIN PEPTIDES AND THE EFFECTS OF CYCLIZATION
DS DOROW, PT SHI, FR CARBONE, E MINASIAN, PEE TODD, SJ LEACH
Journal article | 1985 | Molecular Immunology
Peptides corresponding to sequences (72-88) and (26-54) of beef myoglobin have been synthesised in their open-chain and cyclised f..
Honours, Awards and Fellowships
Australian-American Fulbright Senior Scholar Award
FAA - Fellow of the Australian Academy of Science
Microbiology And Immunology
American Association of Immunologist
Australasian Society for Immunology
Doctor of Philosophy
University of Melbourne
Bachelor of Science
University of Melbourne