Lynn Corcoran

Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii)

Amanda L Patchett, Tim HH Coorens, Jocelyn Darby, Richard Wilson, Matthew J McKay, Karthik S Kamath, Alan Rubin, Matthew Wakefield, Lachlan Mcintosh, Stefano Mangiola, Ruth J Pye, Andrew S Flies, Lynn M Corcoran, A Bruce Lyons, Gregory M Woods, Elizabeth P Murchison, Anthony T Papenfuss, Cesar Tovar

Journal article  |  2020  |  Cellular and Molecular Life Sciences

Devil facial tumour disease (DFTD) comprises two genetically distinct transmissible cancers (DFT1 and DFT2) endangering the surviv..

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

Tom Sidwell, Yang Liao, Alexandra L Garnham, Ajithkumar Vasanthakumar, Renee Gloury, Jonas Blume, Peggy P Teh, David Chisanga, Christoph Thelemann, Fabian de Labastida Rivera, Christian R Engwerda, Lynn Corcoran, Kohei Kometani, Tomohiro Kurosaki, Gordon K Smyth, Wei Shi, Axel Kallies

Journal article  |  2020  |  Nature Communications

Differentiation and homeostasis of Foxp3+ regulatory T (Treg) cells are strictly controlled by T-cell receptor (TCR) signals; howe..

Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord

Gauhar Masgutova, Audrey Harris, Benvenuto Jacob, Lynn M Corcoran, Frederic Clotman

Journal article  |  2019  |  Frontiers in Molecular Neuroscience

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

Jai Rautela, Laura F Dagley, Tobias Kratina, Angaleena Anthony, Wilford Goh, Elliot Surgenor, Rebecca B Delconte, Andrew I Webb, Ngaire Elwood, Joanna R Groom, Fernando Souza-Fonseca-Guimaraes, Lynn Corcoran, Nicholas D Huntington

Journal article  |  2019  |  Molecular Immunology

NK cells are cytotoxic lymphocytes with a key role in limiting tumour metastases. In mice, the NK cell lineage continually express..

Class-Switch Recombination Occurs Infrequently in Germinal Centers

Jonathan A Roco, Luka Mesin, Sebastian C Binder, Christian Nefzger, Paula Gonzalez-Figueroa, Pablo F Canete, Julia Ellyard, Qian Shen, Philippe A Robert, Jean Cappello, Harpreet Vohra, Yang Zhang, Carla R Nowosad, Arien Schiepers, Lynn M Corcoran, Kai-Michael Toellner, Jose M Polo, Michael Meyer-Hermann, Gabriel D Victora, Carola G Vinuesa

Journal article  |  2019  |  Immunity

Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord

Audrey Harris, Gauhar Masgutova, Amandine Collin, Mathilde Toch, Maria Hidalgo-Figueroa, Benvenuto Jacob, Lynn M Corcoran, Cedric Francius, Frederic Clotman

Journal article  |  2019  |  Frontiers in Cellular Neuroscience

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Michael Chopin, Aaron T Lun, Yifan Zhan, Jaring Schreuder, Hannah Coughlan, Angela D'Amico, Lisa A Mielke, Francisca F Almeida, Andrew J Kueh, Ross A Dickins, Gabrielle T Belz, Shalin H Naik, Andrew M Lew, Phillipe Bouillet, Marco J Herold, Gordon K Smyth, Lynn M Corcoran, Stephen L Nutt

Journal article  |  2019  |  Immunity

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans

Jarny Choi, Tracey M Baldwin, Mae Wong, Jessica E Bolden, Kirsten A Fairfax, Erin C Lucas, Rebecca Cole, Christine Biben, Clare Morgan, Kerry A Ramsay, Ashley P Ng, Maria Kauppi, Lynn M Corcoran, Wei Shi, Nick Wilson, Michael J Wilson, Warren S Alexander, Douglas J Hilton, Carolyn A de Graaf

Journal article  |  2019  |  NUCLEIC ACIDS RESEARCH

Germline-activating mutations in PIK3CD compromise B cell development and function

Danielle T Avery, Alisa Kane, Tina Nguyen, Anthony Lau, Akira Nguyen, Helen Lenthall, Kathryn Payne, Wei Shi, Henry Brigden, Elise French, Julia Bier, Jana R Hermes, David Zahra, William A Sewell, Danyal Butt, Michael Elliott, Kaan Boztug, Isabelle Meyts, Sharon Choo, Peter Hsu, et al.

Journal article  |  2018  |  Journal of Experimental Medicine

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins

Stephanie Trezise, Alexander Karnowski, Pasquale L Fedele, Sridurga Mithraprabhu, Yang Liao, Kathy D'Costa, Andrew J Kueh, Matthew P Hardy, Catherine M Owczarek, Marco J Herold, Andrew Spencer, Wei Shi, Simon N Willis, Stephen L Nutt, Lynn M Corcoran

Journal article  |  2018  |  International Journal of Molecular Sciences

Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release

Ruth Pye, Amanda Patchett, Elspeth McLennan, Russell Thomson, Scott Carver, Samantha Fox, David Pemberton, Alexandre Kreiss, Adriana Baz Morelli, Anabel Silva, Martin J Pearse, Lynn M Corcoran, Katherine Belov, Carolyn J Hogg, Gregory M Woods, A Bruce Lyons

Journal article  |  2018  |  Frontiers in Immunology

Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells

AL Patchett, R Wilson, JC Charlesworth, LM Corcoran, AT Papenfuss, AB Lyons, GM Woods, C Tovar

Journal article  |  2018  |  Oncotarget

The toll-like receptor ligands Hiltonol (R) (polyICLC) and imiquimod effectively activate antigen-specific immune responses in Tasmanian devils (Sarcophilus harrisii)

Amanda L Patchett, Cesar Tovar, Lynn M Corcoran, A Bruce Lyons, Gregory M Woods

Journal article  |  2017  |  Developmental & Comparative Immunology

IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation

Stephane Chevrier, Tobias Kratina, Dianne Emslie, David M Tarlinton, Lynn M Corcoran

Journal article  |  2017  |  Immunology & Cell Biology

Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils

Cesar Tovar, Ruth J Pye, Alexandre Kreiss, Yuanyuan Cheng, Gabriella K Brown, Jocelyn Darby, Roslyn C Malley, Hannah VT Siddle, Karsten Skjodt, Jim Kaufman, Anabel Silva, Adriana Baz Morelli, Anthony T Papenfuss, Lynn M Corcoran, James M Murphy, Martin J Pearse, Katherine Belov, A Bruce Lyons, Gregory M Woods

Journal article  |  2017  |  Scientific Reports

A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

Susanne Heinzel, Binh Giang Tran, Andrey Kan, Julia M Marchingo, Bryan K Lye, Lynn M Corcoran, Philip D Hodgkin

Journal article  |  2017  |  Nature Immunology

PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-gamma and Can Be Expressed in the Tumor Microenvironment

Andrew S Flies, A Bruce Lyons, Lynn M Corcoran, Anthony T Papenfuss, James M Murphy, Graeme W Knowles, Gregory M Woods, John D Hayball

Journal article  |  2016  |  Frontiers in Immunology

Mitogen-activated Tasmanian devil blood mononuclear cells kill devil facial tumour disease cells

Gabriella K Brown, Cesar Tovar, Anne A Cooray, Alexandre Kreiss, Jocelyn Darby, James M Murphy, Lynn M Corcoran, Silvana S Bettiol, A Bruce Lyons, Gregory M Woods

Journal article  |  2016  |  Immunology & Cell Biology

Long-Lived Plasma Cells Have a Sweet Tooth

Lynn M Corcoran, Stephen L Nutt

Journal article  |  2016  |  Immunity

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

Margherita Ghisi, Lev Kats, Frederick Masson, Jason Li, Tobias Kratina, Eva Vidacs, Omer Gilan, Maria A Doyle, Andrea Newbold, Jessica E Bolden, Kirsten A Fairfax, Carolyn A de Graaf, Matthew Firth, Johannes Zuber, Ross A Dickins, Lynn M Corcoran, Mark A Dawson, Gabrielle T Belz, Ricky W Johnstone

Journal article  |  2016  |  Cancer Cell

Characterisation of CD4 T cells in healthy and diseased koalas (Phascolarctos cinereus) using cell-type-specific monoclonal antibodies

Chandan Mangar, Charles W Armitage, Peter Timms, Lynn M Corcoran, Kenneth W Beagley

Journal article  |  2016  |  Developmental & Comparative Immunology

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

SHM Pang, M Minnich, P Gangatirkar, Z Zheng, A Ebert, G Song, RA Dickins, LM Corcoran, CG Mullighan, M Busslinger, ND Huntington, SL Nutt, S Carotta

Journal article  |  2016  |  Leukemia

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development

Renee Gloury, Dimitra Zotos, Malou Zuidscherwoude, Frederick Masson, Yang Liao, Jhaguaral Hasbold, Lynn M Corcoran, Phil D Hodgkin, Gabrielle T Belz, Wei Shi, Stephen L Nutt, David M Tarlinton, Axel Kallies

Journal article  |  2016  |  The Journal of Experimental Medicine

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

Michael Chopin, Simon P Preston, Aaron TL Lun, Julie Tellier, Gordon K Smyth, Marc Pellegrini, Gabrielle T Belz, Lynn M Corcoran, Jane E Visvader, Li Wu, Stephen L Nutt

Journal article  |  2016  |  Cell Reports

NF kappa B1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

Elisha de Valle, George Grigoriadis, Lorraine A O'Reilly, Simon N Willis, Mhairi J Maxwell, Lynn M Corcoran, Evelyn Tsantikos, Jasper KS Cornish, Kirsten A Fairfax, Ajithkumar Vasanthakumar, Mark A Febbraio, Margaret L Hibbs, Marc Pellegrini, Ashish Banerjee, Philip D Hodgkin, Axel Kallies, Fabienne Mackay, Andreas Strasser, Steve Gerondakis, Raffi Gugasyan

Journal article  |  2016  |  Journal of Experimental Medicine

Regulation of germinal center responses, memory B cells and plasma cell formation - an update

Lynn M Corcoran, David M Tarlinton

Journal article  |  2016  |  Current Opinion in Immunology

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

Rebecca B Delconte, Wei Shi, Priyanka Sathe, Takashi Ushiki, Cyril Seillet, Martina Minnich, Tatiana B Kolesnik, Lucille C Rankin, Lisa A Mielke, Jian-Guo Zhang, Meinrad Busslinger, Mark J Smyth, Dana S Hutchinson, Stephen L Nutt, Sandra E Nicholson, Warren S Alexander, Lynn M Corcoran, Eric Vivier, Gabrielle T Belz, Sebastian Carotta, et al.

Journal article  |  2016  |  Immunity

The flavors of plasma cells

Lynn M Corcoran, Stephen L Nutt

Journal article  |  2015  |  Oncotarget

Immunology of a Transmissible Cancer Spreading among Tasmanian Devils

Gregory M Woods, Lauren J Howson, Gabriella K Brown, Cesar Tovar, Alexandre Kreiss, Lynn M Corcoran, A Bruce Lyons

Journal article  |  2015  |  The Journal of Immunology

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

Wei Shi, Yang Liao, Simon N Willis, Nadine Taubenheim, Michael Inouye, David M Tarlinton, Gordon K Smyth, Philip D Hodgkin, Stephen L Nutt, Lynn M Corcoran

Journal article  |  2015  |  Nature Immunology

The generation of antibody-secreting plasma cells

Stephen L Nutt, Philip D Hodgkin, David M Tarlinton, Lynn M Corcoran

Journal article  |  2015  |  Nature Reviews Immunology

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

Sebastian Carotta, Simon N Willis, Jhagvaral Hasbold, Michael Inouye, Swee Heng Milon Pang, Dianne Emslie, Amanda Light, Michael Chopin, Wei Shi, Hongsheng Wang, Herbert C Morse, David M Tarlinton, Lynn M Corcoran, Philip D Hodgkin, Stephen L Nutt

Journal article  |  2014  |  Journal of Experimental Medicine

BTB-ZF transcription factors, a growing family of regulators of early and late B-cell development

Stephane Chevrier, Lynn M Corcoran

Journal article  |  2014  |  Immunology and Cell Biology

The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity

Stephane Chevrier, Dianne Emslie, Wei Shi, Tobias Kratina, Cameron Wellard, Alexander Karnowski, Erdem Erikci, Gordon K Smyth, Kamal Chowdhury, David Tarlinton, Lynn M Corcoran

Journal article  |  2014  |  Journal of Experimental Medicine

Identification of Dendritic Cells, B Cell and T Cell Subsets in Tasmanian Devil Lymphoid Tissue; Evidence for Poor Immune Cell Infiltration into Devil Facial Tumors

Lauren J Howson, Katrina M Morris, Takumi Kobayashi, Cesar Tovar, Alexandre Kreiss, Anthony T Papenfuss, Lynn Corcoran, Katherine Belov, Gregory M Woods

Journal article  |  2014  |  The Anatomical Record

Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell-Intrinsic Mechanism

Simon N Willis, Kim L Good-Jacobson, Joan Curtis, Amanda Light, Julie Tellier, Wei Shi, Gordon K Smyth, David M Tarlinton, Gabrielle T Belz, Lynn M Corcoran, Axel Kallies, Stephen L Nutt

Journal article  |  2014  |  Journal of Immunology

Oct2 and Obf1 as facilitators of B:T cell collaboration during a humoral immune response

Lynn Corcoran, Dianne Emslie, Tobias Kratina, Wei Shi, Susanne Hirsch, Nadine Taubenheim, Stephane Chevrier

Journal article  |  2014  |  Frontiers in Immunology

Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas

Shoukat Afshar-Sterle, Dimitra Zotos, Nicholas J Bernard, Anna K Scherger, Lisa Roedling, Amber E Alsop, Jennifer Walker, Frederick Masson, Gabrielle T Belz, Lynn M Corcoran, Lorraine A O'Reilly, Andreas Strasser, Mark J Smyth, Ricky Johnstone, David M Tarlinton, Stephen L Nutt, Axel Kallies

Journal article  |  2014  |  Nature Medicine

Germinal center-independent, IgM-mediated autoimmunity in sanroque mice lacking Obf1

Stephane Chevrier, Tobias Kratina, Dianne Emslie, Alexander Karnowski, Lynn M Corcoran

Journal article  |  2014  |  Immunology and Cell Biology

MiR-210 Is Induced by Oct-2, Regulates B Cells, and Inhibits Autoantibody Production

Yingting Mok, Vera Schwierzeck, David C Thomas, Elena Vigorito, Tim F Rayner, Lorna B Jarvis, Haydn M Prosser, Allan Bradley, David R Withers, Inga-Lill Martensson, Lynn M Corcoran, Cherie Blenkiron, Eric A Miska, Paul A Lyons, Kenneth GC Smith

Journal article  |  2013  |  The Journal of Immunology

Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells

Priyanka Sathe, David Vremec, Li Wu, Lynn Corcoran, Ken Shortman

Journal article  |  2013  |  Blood

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

Alex Karnowski, Stephane Chevrier, Gabrielle T Belz, Adele Mount, Dianne Emslie, Kathy D'Costa, David M Tarlinton, Axel Kallies, Lynn M Corcoran

Journal article  |  2012  |  Journal of Experimental Medicine

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

Nadine Taubenheim, David M Tarlinton, Simon Crawford, Lynn M Corcoran, Philip D Hodgkin, Stephen L Nutt

Journal article  |  2012  |  Journal of Immunology

The genetic network controlling plasma cell differentiation

Stephen L Nutt, Nadine Taubenheim, Jhagvaral Hasbold, Lynn M Corcoran, Philip D Hodgkin

Journal article  |  2011  |  Seminars in Immunology

Plasma cell development and survival

Sarah A Oracki, Jennifer A Walker, Margaret L Hibbs, Lynn M Corcoran, David M Tarlinton

Journal article  |  2010  |  Immunological Reviews

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

Dimitra Zotos, Jonathan M Coquet, Yang Zhang, Amanda Light, Kathy D'Costa, Axel Kallies, Lynn M Corcoran, Dale I Godfrey, Kai-Michael Toellner, Mark J Smyth, Stephen L Nutt, David M Tarlinton

Journal article  |  2010  |  Journal of Experimental Medicine

Blimp1 is limiting for transformation in a mouse plasmacytoma model

Kathy D'Costa, Dianne Emslie, Donald Metcalf, Gordon K Smyth, Alexander Karnowski, Axel Kallies, Stephen L Nutt, Lynn M Corcoran

Journal article  |  2009  |  Blood

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses.

Ye Zheng, Ashutosh Chaudhry, Arnold Kas, Paul deRoos, Jeong M Kim, Tin-Tin Chu, Lynn Corcoran, Piper Treuting, Ulf Klein, Alexander Y Rudensky

Journal article  |  2009  |  Nature

In the course of infection or autoimmunity, particular transcription factors orchestrate the differentiation of T(H)1, T(H)2 or T(..

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

Stephane Chevrier, Celine Genton, Axel Kallies, Alexander Karnowski, Luc A Otten, Bernard Malissen, Marie Malissen, Marina Botto, Lynn M Corcoran, Stephen L Nutt, Hans Acha-Orbea

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation.

Elias Theodorou, George Dalembert, Christopher Heffelfinger, Eric White, Sherman Weissman, Lynn Corcoran, Michael Snyder

Journal article  |  2009  |  Genes & Development

Neuronal differentiation is a complex process that involves a plethora of regulatory steps. To identify transcription factors that..

Silencing and Nuclear Repositioning of the lambda 5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1

Alexander Karnowski, Chun Cao, Gabriele Matthias, Sebastian Carotta, Lynn M Corcoran, Inga-Lill Martensson, Jane A Skok, Patrick Matthias

Journal article  |  2008  |  PLoS ONE

Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells

Dianne Emslie, Kathy D'Costa, Jhagvaral Hasbold, Donald Metcalf, Kiyoshi Takatsu, Philip O Hodgkin, Lynn M Corcoran

Journal article  |  2008  |  Journal of Experimental Medicine

Identification of Pax5 target genes in early B cell differentiation

Clare Pridans, Melissa L Holmes, Matthew Polli, James M Wettenhall, Aleksandar Dakic, Lynn M Corcoran, Gordon K Smyth, Stephen L Nutt

Journal article  |  2008  |  Journal of Immunology

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5( ) T follicular helper cells

Vanessa L Bryant, Cindy S Ma, Danielle T Avery, Ying Li, Kim L Good, Lynn M Corcoran, Rene de Waal Malefyt, Stuart G Tangye

Journal article  |  2007  |  The Journal of Immunology

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1

Axel Kallies, Jhagvaral Hasbold, Kirsten Fairfax, Clare Pridans, Dianne Emslie, Brent S McKenzie, Andrew M Lew, Lynn M Corcoran, Philip D Hodgkin, David M Tarlinton, Stephen L Nutt

Journal article  |  2007  |  Immunity

Different kinetics of Blimp-1 induction in B cell subsets revealed by reporter gene

Kirsten A Fairfax, Lynn M Corcoran, Clare Pridans, Nicholas D Huntington, Axel Kallies, Stephen L Nutt, David M Tarlinton

Journal article  |  2007  |  J. Immunol.

An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment

Liang Zhou, Aaron A Nazarian, Jian Xu, Dean Tantin, Lynn M Corcoran, Stephen T Smale

Journal article  |  2007  |  Molecular and Cellular Biology

Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes

Alicia Oshlack, Dianne Emslie, Lynn M Corcoran, Gordon K Smyth

Journal article  |  2007  |  Genome Biology

Erratum: B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1 (Nature Immunology (2001) vol. 2 (69-74))

K Schubart, S Massa, D Schubart, LM Corcoran, AG Rolink, P Matthias

Journal article  |  2006  |  Nature Immunology

The Ets factor Spi-B is a direct critical target of the coactivator OBF-1

Boris Bartholdy, Camille Du Roure, Alain Bordon, Dianne Emslie, Lynn M Corcoran, Patrick Matthias

Journal article  |  2006  |  Proceedings of the National Academy of Sciences

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

A Kallies, ED Hawkins, GT Belz, D Metcalf, M Hommel, LM Corcoran, PD Hodgkin, SL Nutt

Journal article  |  2006  |  Nat. Immunol.

Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells

T Thomas, LM Corcoran, R Gugasyan, MP Dixon, T Brodnicki, SL Nutt, D Metcalf, AK Voss

Journal article  |  2006  |  Genes Dev.

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

ML Holmes, S Carotta, LM Corcoran, SL Nutt

Journal article  |  2006  |  Genes & Development

Erratum: Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients (Journal of Immunology (2005) 175 (5498-5503))

N Taubenheim, M Von Hornung, A Durandy, K Warnatz, L Corcoran, HH Peter, H Eibel

Journal article  |  2006  |  Journal of Immunology

Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients.

Nadine Taubenheim, Marcus von Hornung, Anne Durandy, Klaus Warnatz, Lynn Corcoran, Hans-Hartmut Peter, Hermann Eibel

Journal article  |  2005  |  The Journal of Immunology

Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by defective Ab production and recurrent bacteri..

Development of murine plasmacytoid dendritic cell subsets

SH Naik, LM Corcoran, L Wu

Journal article  |  2005  |  Immunology & Cell Biology

Differential requirement for OBF-1 during antibody-secreting cell differentiation

LM Corcoran, J Hasbold, W Dietrich, E Hawkins, A Kallies, SL Nutt, DM Tarlinton, P Matthias, PD Hodgkin

Journal article  |  2005  |  J. Exp. Med.

Erratum: Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (Journal of Immunology (2005) 174 (4034-4042))

DT Avery, JI Ellyard, F Mackay, LM Corcoran, PD Hodgkin, SG Tangye

Journal article  |  2005  |  Journal of Immunology

Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage

DT Avery, JI Ellyard, F Mackay, LM Corcoran, PD Hodgkin, SG Tangye

Journal article  |  2005  |  The Journal of Immunology

Transcriptional control of B cell activation

LM Corcoran

Book  |  2005  |  Current Topics in Microbiology and Immunology

Plasma cell ontogeny defined by quantitative changes in Blimp-1 expression

A Kallies, J Hasbold, DM Tarlinton, W Dietrich, LM Corcoran, PD Hodgkin, SL Nutt

Journal article  |  2004  |  J. Exp. Med.

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

J Hasbold, LM Corcoran, DM Tarlinton, SG Tangye, PD Hodgkin

Journal article  |  2004  |  Nature Immunology

Knockout B lymphoma cell lines as biochemical tools to explore multiple signalling pathways

MF Veale, WM Dietrich, LM Corcoran

Journal article  |  2003  |  Immunology & Cell Biology

The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells.

Lynn Corcoran, Isabel Ferrero, David Vremec, Karen Lucas, Jason Waithman, Meredith O'Keeffe, Li Wu, Anne Wilson, Ken Shortman

Journal article  |  2003  |  The Journal of Immunology

There has been controversy over the possible lymphoid origin of certain dendritic cell (DC) subtypes. To resolve this issue, DC an..

Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages

L Corcoran, D Vremec, M Febbraio, T Baldwin, E Handman

Journal article  |  2002  |  International Immunology

CD36 is differentially expressed by CD8( ) splenic dendritic cells but is not required for cross-presentation in vivo

GT Belz, D Vremec, M Febbraio, L Corcoran, K Shortman, FR Carbone, WR Heath

Journal article  |  2002  |  Journal of Immunology

Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1

P Shore, W Dietrich, LM Corcoran

Journal article  |  2002  |  Nucleic Acids Research

Expression and purification of glutathione-S-transferase fusion proteins.

DB Smith, LM Corcoran

Journal article  |  2001  |  Current Protocols in Molecular Biology

This unit describes how pGEX vectors can be used in bacterial systems to express foreign polypeptides as fusions with glutathione-..

B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1

K Schubart, S Massa, D Schubart, LM Corcoran, AG Rolink, P Matthias

Journal article  |  2001  |  Nature Immunology

Transcription factors in B-cell development and function

L Corcoran, P Shore

Journal article  |  2000  |  Immunologist

IL-5 and Rp105 signaling defects in B cells from commonly used 129 mouse substrains

LM Corcoran, D Metcalf

Journal article  |  1999  |  Journal of Immunology

Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an E mu-myc transgene

LM Corcoran, S Tawfilis, LJ Barlow

Journal article  |  1999  |  Journal of Immunological Methods

The linkage between T-cell and dendritic cell development in the mouse thymus

K Shortman, D Vremec, LM Corcoran, K Georgopoulos, K Lucas, L Wu

Journal article  |  1998  |  Immunological Reviews

Oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function

PO Humbert, LM Corcoran

Journal article  |  1997  |  Journal of Immunology

Continued differentiation during B lymphopoiesis requires signals in addition to cell survival

DM Tarlinton, LM Corcoran, A Strasser

Journal article  |  1997  |  International Immunology

Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo

LA OReilly, AW Harris, DM Tarlinton, LM Corcoran, A Strasser

Journal article  |  1997  |  Journal of Immunology

Family-specific differences in transcription efficiency of Ig heavy chain promoters

KL Buchanan, EA Smith, SS Dou, LM Corcoran, CF Webb

Journal article  |  1997  |  Journal of Immunology

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1(-/-) mice

E Maraskovsky, LA OReilly, M Teepe, LM Corcoran, JJ Peschon, A Strasser

Journal article  |  1997  |  Cell

Nerve growth factor-regulated properties of sensory neurones in Oct-2 null mutant mice.

NN Ninkina, VL Buchman, AN Akopian, SN Lawson, M Yamamoto, E Campbell, L Corcoran, JN Wood

Journal article  |  1995  |  Molecular Brain Research

The POU-domain transcription factor Oct-2 is expressed in both B lymphocytes and sensory neurones, where its expression is regulat..

IDENTIFICATION OF CD36 AS THE FIRST GENE DEPENDENT ON THE B-CELL DIFFERENTIATION FACTOR OCT-2

H KONIG, P PFISTERER, LM CORCORAN, T WIRTH

Journal article  |  1995  |  Genes & Development

SCID MICE RECONSTITUTED WITH OCT-2-DEFICIENT LYMPHOCYTES CAN CURE LEISHMANIA-MAJOR INFECTION AND GENERATE NORMAL ANTIGEN-SPECIFIC T-CELLS

JPY SCHEERLINCK, LM CORCORAN, E HANDMAN

Journal article  |  1995  |  Immunology Letters

Plasmodium falciparum: mapping the membrane-binding domain in the ring-infected erythrocyte surface antigen.

M Foley, L Corcoran, L Tilley, R Anders

Journal article  |  1994  |  Experimental Parasitology

The ring-infected erythrocyte surface antigen (RESA) associates with spectrin in the erythrocyte membrane (Foley, M., Tilley, L., ..

OCT-2 IS REQUIRED EARLY IN T-CELL-INDEPENDENT B-CELL ACTIVATION FOR G1 PROGRESSION AND FOR PROLIFERATION

LM CORCORAN, M KARVELAS

Journal article  |  1994  |  Immunity

FUNCTIONAL IMMUNOGLOBULIN TRANSGENES GUIDE ORDERED B-CELL DIFFERENTIATION IN RAG-1-DEFICIENT MICE

E SPANOPOULOU, CAJ ROMAN, LM CORCORAN, MS SCHLISSEL, DP SILVER, D NEMAZEE, MC NUSSENZWEIG, SA SHINTON, RR HARDY, D BALTIMORE

Journal article  |  1994  |  Genes & Development

DIFFERENTIAL TRANSACTIVATION POTENTIAL OF OCT1 AND OCT2 IS DETERMINED BY ADDITIONAL B-CELL-SPECIFIC ACTIVITIES

P PFISTERER, A ANNWEILER, C ULLMER, LM CORCORAN, T WIRTH

Journal article  |  1994  |  The EMBO Journal

BCL-2 EXPRESSION PROMOTES B-LYMPHOID BUT NOT T-LYMPHOID DEVELOPMENT IN SCID MICE

A STRASSER, AW HARRIS, LM CORCORAN, S CORY

Journal article  |  1994  |  Nature

ENHANCED CELL-SURVIVAL AND TUMORIGENESIS

S CORY, A STRASSER, T JACKS, LM CORCORAN, T METZ, AW HARRIS, JM ADAMS

Conference Proceedings  |  1994  |  Cold Spring Harbor Symposia on Quantitative Biology

OCT-2, ALTHOUGH NOT REQUIRED FOR EARLY B-CELL DEVELOPMENT, IS CRITICAL FOR LATER B-CELL MATURATION AND FOR POSTNATAL SURVIVAL

LM CORCORAN, M KARVELAS, GJV NOSSAL, ZS YE, T JACKS, D BALTIMORE

Journal article  |  1993  |  Genes & Development

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription.

MS Schlissel, LM Corcoran, D Baltimore

Journal article  |  1991  |  The Journal of Experimental Medicine

Virus-transformed pre-B cells undergo ordered immunoglobulin (Ig) gene rearrangements during culture. We devised a series of highl..

The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2.

MP Kamps, L Corcoran, JH LeBowitz, D Baltimore

Journal article  |  1990  |  Molecular and Cellular Biology

The gene encoding interleukin-2 (IL-2) contains a sequence 52 to 326 nucleotides upstream of its transcriptional initiation site t..

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

W Herr, RA Sturm, RG Clerc, LM Corcoran, D Baltimore, PA Sharp, HA Ingraham, MG Rosenfeld, M Finney, G Ruvkun

Journal article  |  1988  |  Genes & Development

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

RG Clerc, LM Corcoran, JH LeBowitz, D Baltimore, PA Sharp

Journal article  |  1988  |  Genes & Development

Transcription of promoters of immunoglobulin genes is controlled by an octanucleotide sequence element. The sequence of a cDNA enc..

GM-CSF PRODUCED BY RECOMBINANT VACCINIA VIRUS OR IN GM-CSF TRANSGENIC MICE HAS NO EFFECT INVIVO ON MURINE CUTANEOUS LEISHMANIASIS

LM CORCORAN, D METCALF, SJ EDWARDS, E HANDMAN

Journal article  |  1988  |  The Journal of Parasitology

HOMOLOGOUS RECOMBINATION WITHIN SUBTELOMERIC REPEAT SEQUENCES GENERATES CHROMOSOME SIZE POLYMORPHISMS IN P-FALCIPARUM

LM CORCORAN, JK THOMPSON, D WALLIKER, DJ KEMP

Journal article  |  1988  |  Cell

IMMUNIZATION TRIALS WITH THE RING-INFECTED ERYTHROCYTE SURFACE-ANTIGEN OF PLASMODIUM-FALCIPARUM IN OWL MONKEYS (AOTUS-VOCIFERANS)

WE COLLINS, M PAPPAIOANOU, RF ANDERS, GH CAMPBELL, GV BROWN, DJ KEMP, JR BRODERSON, RL COPPEL, JC SKINNER, PM PROCELL, JM FAVALORO, LM CORCORAN, NSF MA, GF MITCHELL, CC CAMPBELL

Journal article  |  1988  |  The American Journal of Tropical Medicine and Hygiene

A 2ND ANTIGENIC HEAT-SHOCK PROTEIN OF PLASMODIUM-FALCIPARUM

MG PETERSON, PE CREWTHER, JK THOMPSON, LM CORCORAN, RL COPPEL, GV BROWN, RF ANDERS, DJ KEMP

Journal article  |  1988  |  DNA

MOLECULAR KARYOTYPE OF PLASMODIUM-FALCIPARUM - CONSERVED LINKAGE GROUPS AND EXPENDABLE HISTIDINE-RICH PROTEIN GENES

DJ KEMP, JK THOMPSON, D WALLIKER, LM CORCORAN

Journal article  |  1987  |  Proceedings of the National Academy of Sciences

GENETIC-ANALYSIS OF THE HUMAN MALARIA PARASITE PLASMODIUM-FALCIPARUM

D WALLIKER, IA QUAKYI, TE WELLEMS, TF MCCUTCHAN, A SZARFMAN, WT LONDON, LM CORCORAN, TR BURKOT, R CARTER

Journal article  |  1987  |  Science

EXPRESSION OF PARASITE ANTIGENS IN ESCHERICHIA-COLI

P MCINTYRE, RL COPPEL, DB SMITH, HD STAHL, LM CORCORAN, CJ LANGFORD, JM FAVALORO, PE CREWTHER, GV BROWN, GF MITCHELL, RF ANDERS, DJ KEMP

Journal article  |  1987  |  International Journal for Parasitology

The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice.

S Cory, AW Harris, WY Langdon, WS Alexander, LM Corcoran, RD Palmiter, CA Pinkert, RL Brinster, JM Adams

Journal article  |  1987  |  Haematology and blood transfusion

STRUCTURE OF THE RESA GENE OF PLASMODIUM-FALCIPARUM

JM FAVALORO, RL COPPEL, LM CORCORAN, SJ FOOTE, GV BROWN, RF ANDERS, DJ KEMP

Journal article  |  1986  |  Nucleic Acids Research

IMMUNIZATION OF AOTUS MONKEYS WITH RECOMBINANT PROTEINS OF AN ERYTHROCYTE SURFACE-ANTIGEN OF PLASMODIUM-FALCIPARUM

WE COLLINS, RF ANDERS, M PAPPAIOANOU, GH CAMPBELL, GV BROWN, DJ KEMP, RL COPPEL, JC SKINNER, PM ANDRYSIAK, JM FAVALORO, LM CORCORAN, JR BRODERSON, GF MITCHELL, CC CAMPBELL

Journal article  |  1986  |  Nature

CHROMOSOMES OF PLASMODIUM-FALCIPARUM

LM CORCORAN, DJ KEMP

Journal article  |  1986  |  Papua and New Guinea medical journal

GENES FOR ANTIGENS OF PLASMODIUM-FALCIPARUM

DJ KEMP, RL COPPEL, HD STAHL, AE BIANCO, LM CORCORAN, P MCINTYRE, CJ LANGFORD, JM FAVALORO, PE CREWTHER, GV BROWN, GF MITCHELL, JG CULVENOR, RF ANDERS

Journal article  |  1986  |  Parasitology

Genes For Antigens of Plasmodium Falciparum

DJ Kemp, RL Coppel, HD Stahl, AE Bianco, LM Corcoran, P McIntyre, CJ Langford, JM Favaloro, PE Crewther, GV Brown, GF Mitchell, JG Culvenor

Journal article  |  1986  |  Parasitology

Sporozoites ofP. falciparumand other Plasmodia appear to be fairly simple antigenically, in that there is a dominant antigen, the ..

C-MYC-INDUCED LYMPHOMAGENESIS IN TRANSGENIC MICE AND THE ROLE OF THE THE PVT-1 LOCUS IN LYMPHOID NEOPLASIA

JM ADAMS, AW HARRIS, WY LANGDON, CA PINKERT, RL BRINSTER, RD PALMITER, L CORCORAN, WS ALEXANDER, MW GRAHAM, S CORY

Journal article  |  1986  |  Current Topics in Microbiology and Immunology

CHROMOSOME SIZE POLYMORPHISMS IN PLASMODIUM-FALCIPARUM CAN INVOLVE DELETIONS AND ARE FREQUENT IN NATURAL PARASITE POPULATIONS

LM CORCORAN, KP FORSYTH, AE BIANCO, GV BROWN, DJ KEMP

Journal article  |  1986  |  Cell

MOLECULAR KARYOTYPES - SEPARATING CHROMOSOMES ON GELS

LM CORCORAN

Journal article  |  1985  |  BioEssays

SIZE VARIATION IN CHROMOSOMES FROM INDEPENDENT CULTURED ISOLATES OF PLASMODIUM-FALCIPARUM

DJ KEMP, LM CORCORAN, RL COPPEL, HD STAHL, AE BIANCO, GV BROWN, RF ANDERS

Journal article  |  1985  |  Nature

VARIANT (6-15) TRANSLOCATIONS IN MURINE PLASMACYTOMAS INVOLVE A CHROMOSOME-15 LOCUS AT LEAST 72 KB FROM THE C-MYC ONCOGENE

S CORY, M GRAHAM, E WEBB, L CORCORAN, JM ADAMS

Journal article  |  1985  |  The EMBO Journal

TRANSPOSITION OF THE IMMUNOGLOBULIN HEAVY-CHAIN ENHANCER TO THE MYC ONCOGENE IN A MURINE PLASMACYTOMA

LM CORCORAN, S CORY, JM ADAMS

Journal article  |  1985  |  Cell

THE C-MYC ONCOGENE DRIVEN BY IMMUNOGLOBULIN ENHANCERS INDUCES LYMPHOID MALIGNANCY IN TRANSGENIC MICE

JM ADAMS, AW HARRIS, CA PINKERT, LM CORCORAN, WS ALEXANDER, S CORY, RD PALMITER, RL BRINSTER

Journal article  |  1985  |  Nature

MURINE T-LYMPHOMAS IN WHICH THE CELLULAR MYC ONCOGENE HAS BEEN ACTIVATED BY RETROVIRAL INSERTION

LM CORCORAN, JM ADAMS, AR DUNN, S CORY

Journal article  |  1984  |  Cell

ACTIVATION OF THE C-MYC ONCOGENE IN B-LYMPHOID AND T-LYMPHOID TUMORS

S CORY, S GERONDAKIS, LM CORCORAN, O BERNARD, E WEBB, JM ADAMS

Journal article  |  1984  |  Current topics in microbiology and immunology

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

JM Adams, S Gerondakis, E Webb, LM Corcoran, S Cory

Journal article  |  1983  |  Proceedings of the National Academy of Sciences of the United States of America