Bang Bui

Progressive impairments in executive function in the APP/PS1 model of Alzheimer's disease as measured by translatable touchscreen testing.

Amy Shepherd, Jeremiah KH Lim, Vicky HY Wong, Ariel M Zeleznikow-Johnston, Leonid Churilov, Christine TO Nguyen, Bang V Bui, Anthony J Hannan, Emma L Burrows

Journal article  |  2021  |  Neurobiol Aging

Executive function deficits in Alzheimer's disease (AD) occur early in disease progression and may be predictive of cognitive decl..

Targeted delivery of LM22A-4 by cubosomes protects retinal ganglion cells in an experimental glaucoma model

Yue Ding, Seong H Chow, Jinying Chen, Anton P Le Brun, Chun-Ming Wu, Anthony P Duff, Yajun Wang, Jiangning Song, Jiang-Hui Wang, Vickie HY Wong, Da Zhao, Tomoharu Nishimura, Tzong-Hsien Lee, Charlotte E Conn, Hsien-Yi Hsu, Bang Bui, Guei-Sheung Liu, Hsin-Hui Shen

Journal article  |  2021  |  ACTA BIOMATERIALIA

Glaucoma, a major cause of irreversible blindness worldwide, is associated with elevated intraocular pressure (IOP) and progressiv..

Retinal hyperspectral imaging in the 5xFAD mouse model of Alzheimer's disease

Jeremiah KH Lim, Qiao-Xin Li, Tim Ryan, Phillip Bedggood, Andrew Metha, Algis J Vingrys, Bang Bui, Christine TO Nguyen

Journal article  |  2021  |  SCIENTIFIC REPORTS

Hyperspectral imaging of the retina has recently been posited as a potentially useful form of spectroscopy of amyloid-beta (Aβ) pr..

Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1

Jiaheng Xie, Patricia R Jusuf, Bang Bui, Stefanie Dudczig, Tamar E Sztal, Patrick T Goodbourn

Journal article  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Purpose: The human PDZK1 gene is located in a genomic susceptibility region for neurodevelopmental disorders. A genome-wide associ..

Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout

Anna YM Wang, Vickie HY Wong, Pei Ying Lee, Bang V Bui, Stefanie Dudczig, Kirstan A Vessey, Erica L Fletcher

Journal article  |  2021  |  SCIENTIFIC REPORTS

There is increasing evidence for the vulnerability of specific retinal ganglion cell (RGC) types in those with glaucoma and in ani..

Ultra-High Field Magnetic Resonance Imaging of the Retrobulbar Optic Nerve, Subarachnoid Space, and Optic Nerve Sheath in Emmetropic and Myopic Eyes

Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick

Journal article  |  2021  |  Translational Vision Science & Technology

Purpose: We aimed to image the optic nerve, subarachnoid space and optic nerve sheath in emmetropes and myopes ultra-high field (7..

MR-EYE: High-Resolution MRI of the Human Eye and Orbit at Ultrahigh Field (7T)

Rebecca K Glarin, Bao N Nguyen, Jon O Cleary, Scott C Kolbe, Roger J Ordidge, Bang Bui, Allison M McKendrick, Bradford A Moffat

Journal article  |  2021  |  Magnetic Resonance Imaging Clinics of North America

Key points • Dedicated eye imaging can be implemented at 7T to acquire high-resolution, high contrast-to-noise, and high signal-to..

Downregulation of Retinal Connexin 43 in GFAP-Expressing Cells Modifies Vasoreactivity Induced by Perfusion Ocular Pressure Changes

Guodong Liu, Hui Li, Grant Cull, Laura Wilsey, Hongli Yang, Jesica Reemmer, Hai-Ying Shen, Fang Wang, Brad Fortune, Bang V Bui, Lin Wang

Journal article  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Purpose: Glia and their communication via connexin 43 (Cx43) gap junctions are known to mediate neurovascular coupling, a process ..

Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension

Vickie HY Wong, Da Zhao, Bang Bui, Cameron J Millar, Christine TO Nguyen

Journal article  |  2021  |  EXPERIMENTAL EYE RESEARCH

PURPOSE: To investigate changes in aqueous humor dynamics during intraocular pressure (IOP) elevation induced by circumlimbal sutu..

Detection of retinal and blood A beta oligomers with nanobodies

Umma Habiba, Joseph Descallar, Fabian Kreilaus, Utpal K Adhikari, Sachin Kumar, John W Morley, Bang Bui, Maya K Hamaoui, Mourad Tayebi

Journal article  |  2021  |  ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING

Introduction: Abnormal retinal changes are increasingly recognized as an early pathological change in Alzheimer's disease (AD). Al..