Sarah Baines

Population genomics and antimicrobial resistance in Corynebacterium diphtheriae

Melanie Hennart, Leonardo G Panunzi, Carla Rodrigues, Quentin Gaday, Sarah L Baines, Marina Barros-Pinkelnig, Annick Carmi-Leroy, Melody Dazas, Anne Marie Wehenkel, Xavier Didelot, Julie Toubiana, Edgar Badell, Sylvain Brisse

Journal article  |  2020  |  Genome Medicine

BACKGROUND: Corynebacterium diphtheriae, the agent of diphtheria, is a genetically diverse bacterial species. Although antimicrobi..

Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial

Abdoulie Bojang, Sarah L Baines, Bully Camara, Romain Guerillot, Liam Donovan, Raquel Sanchez Marques, Ousman Secka, Umberto D'Alessandro, Christian Bottomley, Benjamin P Howden, Anna Roca

Journal article  |  2020  |  Clinical Infectious Diseases

In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers..

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus

Stefano G Giulieri, Romain Guerillot, Jason C Kwong, Ian R Monk, Ashleigh S Hayes, Diane Daniel, Sarah Baines, Norelle L Sherry, Natasha E Holmes, Peter Ward, Wei Gao, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2020  |  mBio

Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible Stap..

Complete microbial genomes for public health in Australia and the Southwest Pacific

Sarah L Baines, Anders Goncalves da Silva, Glen P Carter, Amy Jennison, Irani Rathnayake, Rikki M Graham, Vitali Sintchenko, Qinning Wang, Rebecca J Rockett, Verlaine J Timms, Elena Martinez, Susan Ballard, Takehiro Tomita, Nicole Isles, Kristy A Horan, William Pitchers, Timothy P Stinear, Deborah A Williamson, Benjamin P Howden, Torsten Seemann

Journal article  |  2020  |  Microbial Genomics

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health ..

Prolonged Exposure to beta-Lactam Antibiotics Reestablishes Susceptibility of Daptomycin-Nonsusceptible Staphylococcus aureus to Daptomycin

Rachel E Jenson, Sarah L Baines, Benjamin P Howden, Nagendra N Mishra, Sabrina Farah, Cassandra Lew, Andrew D Berti, Sanjay K Shukla, Arnold S Bayer, Warren E Rose

Journal article  |  2020  |  Antimicrobial Agents and Chemotherapy

Daptomycin-nonsusceptible (DAP-NS) Staphylococcus aureus often exhibits gain-in-function mutations in the mprF gene (involved in p..

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

Kirstie M Mangas, Andrew H Buultjens, Jessica L Porter, Sarah L Baines, Estelle Marion, Laurent Marsollier, Nicholas J Tobias, Sacha J Pidot, Kylie M Quinn, David J Price, Katherine Kedzierska, Weiguang Zeng, David C Jackson, Brendon Y Chua, Timothy P Stineara

Journal article  |  2020  |  Infection and Immunity

The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with Mycobacterium ulcerans There is no ef..

Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus

Geoffrey W Coombs, Sarah L Baines, Benjamin P Howden, Krister M Swenson, Frances G O'Brien

Journal article  |  2020  |  PLoS One

Production of the Panton-Valentine leukocidin (PVL) by Staphylococcus aureus is mediated via the genes lukS-PV and lukF-PV which a..

Complete microbial genomes for public health in Australia and Southwest Pacific

Sarah Baines, Anders Gonçalves da Silva, Glen Carter, Amy Jennison, Irani Rathnayake, Rikki Graham, Vitali Sintchenko, Qinning Wang, Rebecca Rockett, Verlaine Timms, Elena Martinez, Susan Ballard, Takehiro Tomita, Nicole Isles, Kristy Horan, William Pitchers, Timothy Stinear, Deborah Williamson, Benjamin Howden, Torsten Seemann, et al.

Journal article  |  2019

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health ..

Genomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin

Abdoulie Bojang, Sarah L Baines, Liam Donovan, Romain Guerillot, Kerrie Stevens, Charlie Higgs, Christian Bottomley, Ousman Secka, Mark B Schultz, Anders Goncalves da Silva, Torsten Seemann, Timothy P Stinear, Anna Roca, Benjamin P Howden

Journal article  |  2019  |  Journal of Antimicrobial Chemotherapy

BACKGROUND: Oral azithromycin given during labour reduces carriage of bacteria responsible for neonatal sepsis, including Staphylo..

Co-circulation of Multidrug-resistant Shigella Among Men Who Have Sex With Men in Australia

Danielle J Ingle, Marion Easton, Mary Valcanis, Torsten Seemann, Jason C Kwong, Nicola Stephens, Glen P Carter, Anders Goncalves da Silva, James Adamopoulos, Sarah L Baines, Kathryn E Holt, Eric PF Chow, Christopher K Fairley, Marcus Y Chen, Martyn D Kirk, Benjamin P Howden, Deborah A Williamson

Journal article  |  2019  |  Clinical Infectious Diseases

Background: In urban Australia, the burden of shigellosis is either in returning travellers from shigellosis-endemic regions, or i..