Sarah Baines

Impact of intrapartum oral azithromycin on the acquired macrolide resistome of infants' nasopharynx: a randomised controlled trial.

Abdoulie Bojang, Sarah L Baines, Bully Camara, Romain Guerillot, Liam Donovan, Raquel Sánchez Marqués, Ousman Secka, Umberto D'Alessandro, Christian Bottomley, Benjamin P Howden, Anna Roca

Journal article  |  2020  |  Clinical Infectious Diseases

In a post-hoc analysis of samples from an intra-partum azithromycin randomized-clinical-trial, we found that children whose mother..

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

Kirstie M Mangas, Andrew H Buultjens, Jessica L Porter, Sarah L Baines, Estelle Marion, Laurent Marsollier, Nicholas J Tobias, Sacha J Pidot, Kylie M Quinn, David J Price, Katherine Kedzierska, Weiguang Zeng, David C Jackson, Brendon Y Chua, Timothy P Stineara

Journal article  |  2020  |  Infection and Immunity

The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with Mycobacterium ulcerans There is no ef..

Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus

Geoffrey W Coombs, Sarah L Baines, Benjamin P Howden, Krister M Swenson, Frances G O'Brien

Journal article  |  2020  |  PLOS ONE

Production of the Panton-Valentine leukocidin (PVL) by Staphylococcus aureus is mediated via the genes lukS-PV and lukF-PV which a..

Genomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin

Abdoulie Bojang, Sarah L Baines, Liam Donovan, Romain Guerillot, Kerrie Stevens, Charlie Higgs, Christian Bottomley, Ousman Secka, Mark B Schultz, Anders Goncalves da Silva, Torsten Seemann, Timothy P Stinear, Anna Roca, Benjamin P Howden

Journal article  |  2019  |  Journal of Antimicrobial Chemotherapy

BACKGROUND: Oral azithromycin given during labour reduces carriage of bacteria responsible for neonatal sepsis, including Staphylo..

Co-circulation of Multidrug-resistant Shigella Among Men Who Have Sex With Men in Australia

Danielle J Ingle, Marion Easton, Mary Valcanis, Torsten Seemann, Jason C Kwong, Nicola Stephens, Glen P Carter, Anders Goncalves da Silva, James Adamopoulos, Sarah L Baines, Kathryn E Holt, Eric PF Chow, Christopher K Fairley, Marcus Y Chen, Martyn D Kirk, Benjamin P Howden, Deborah A Williamson

Journal article  |  2019  |  Clinical Infectious Diseases

Background: In urban Australia, the burden of shigellosis is either in returning travellers from shigellosis-endemic regions, or i..

Remodeling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in a Dominant Hospital Lineage of Methicillin-Resistant Staphylococcus aureus

Sarah L Baines, Slade O Jensen, Neville Firth, Anders Goncalves da Silva, Torsten Seemann, Glen P Carter, Deborah A Williamson, Benjamin P Howden, Timothy P Stinear

Journal article  |  2019  |  Antimicrobial Agents and Chemotherapy

Utilizing genomic analyses to investigate the first outbreak of vanA vancomycin-resistant Enterococcus in Australia with emergence of daptomycin non-susceptibility

Abby P Douglas, Caroline Marshall, Sarah L Baines, David Ritchie, Jeff Szer, Victoria Madigan, Hiu Tat Chan, Susan A Ballard, Benjamin P Howden, Kirsty Buising, Monica A Slavin

Journal article  |  2019  |  Journal of Medical Microbiology

Evolution of Daptomycin Resistance in Coagulase-Negative Staphylococci Involves Mutations of the Essential Two-Component Regulator WalKR

Jhih-Hang Jiang, Carina Dexter, David R Cameron, Ian R Monk, Sarah L Baines, Iain J Abbott, Denis W Spelman, Xenia Kostoulias, Cara Nethercott, Benjamin P Howden, Anton Y Peleg

Journal article  |  2019  |  Antimicrobial Agents and Chemotherapy

Capacity To Utilize Raffinose Dictates Pneumococcal Disease Phenotype

Vikrant Minhas, Richard M Harvey, Lauren J McAllister, Torsten Seemann, Anna E Syme, Sarah L Baines, James C Paton, Claudia Trappetti

Journal article  |  2019  |  mBio

The changing landscape of vancomycin-resistant Enterococcus faecium in Australia: a population-level genomic study

Robyn S Lee, Anders Goncalves da Silva, Sarah L Baines, Janet Strachan, Susan Ballard, Glen P Carter, Jason C Kwong, Mark B Schultz, Dieter M Bulach, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2018  |  Journal of Antimicrobial Chemotherapy

Complete Genome Sequences of Bordetella pertussis Clinical Isolate FR5810 and Reference Strain Tohama from Combined Oxford Nanopore and Illumina Sequencing

Valerie Bouchez, Sarah Louise Baines, Sophie Guillot, Sylvain Brisse

Journal article  |  2018  |  Microbiology Resource Announcements

Genomic Analysis of Multiresistant Staphylococcus capitis Associated with Neonatal Sepsis

Glen P Carter, James E Ussher, Anders Gonsalves Da Silva, Sarah L Baines, Helen Heffernan, Thomas Riley, Roland Broadbent, Antje van der Linden, Jean Lee, Ian R Monk, Timothy P Stinear, Benjamin P Howden, Deborah A Williamson

Journal article  |  2018  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Remodelling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in Methicillin-ResistantStaphylococcus aureus

Sarah Baines, Slade Jensen, Neville Firth, Anders Gonçalves da Silva, Torsten Seemann, Glen Carter, Deborah Williamson, Benjamin Howden, Timothy Stinear

Journal article  |  2018

Abstract Staphylococcus aureus is a significant human pathogen whose evolution and adaptation has been shaped in part by mobile ge..

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

Romain Guerillot, Lucy Li, Sarah Baines, Brian Howden, Mark B Schultz, Torsten Seemann, Ian Monk, Sacha J Pidot, Wei Gao, Stefano Giulieri, Anders Goncalves da Silva, Anthony D'Agata, Takehiro Tomita, Anton Y Peleg, Timothy P Stinear, Benjamin P Howden

Journal article  |  2018  |  GENOME MEDICINE

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia

Stefano G Giulieri, Sarah L Baines, Romain Guerillot, Torsten Seemann, Anders Goncalves da Silva, Mark Schultz, Ruth C Massey, Natasha E Holmes, Timothy P Stinear, Benjamin P Howden

Journal article  |  2018  |  Genome Medicine

Daptomycin selects for genetic and phenotypic adaptations leading to antibiotic tolerance in MRSA

Andrew D Berti, Neehal Shukla, Aaron D Rottier, J Sue McCrone, Hannah M Turner, Ian R Monk, Sarah L Baines, Benjamin P Howden, Richard A Proctor, Warren E Rose

Journal article  |  2018  |  Journal of Antimicrobial Chemotherapy

Ceftazidime/avibactam susceptibility by three different susceptibility testing methods in carbapenemase-producing Gram-negative bacteria from Australia

Norelle L Sherry, Sarah L Baines, Benjamin P Howden

Journal article  |  2018  |  International Journal of Antimicrobial Agents

The changing landscape of VREfm in Victoria, Australia: a State-wide genomic snapshot

Robyn Lee, Anders Gonçalves da Silva, Sarah Baines, Janet Strachan, Susan Ballard, Glen Carter, Jason Kwong, Mark Schultz, Dieter Bulach, Torsten Seemann, Timothy Stinear, Benjamin Howden

Journal article  |  2018

Abstract Vancomycin-resistant Enterococcus faecium (VREfm) represent a major source of nosocomial infection worldwide. In Australi..

Genomic Exploration of Within-Host Microevolution Reveals a Distinctive Molecular Signature of Persistent Staphylococcus aureus Bacteraemia

Stefano Giulieri, Sarah Baines, Romain Guerillot, Torsten Semann, Anders Goncalves da Silva, Mark Schultz, Ruth Massey, Natasha Holmes, Timothy Stinear, Benjamin Howden

Journal article  |  2018  |  Genome Medicine

Background: Large-scale genomic studies of within-host evolution during Staphylococcus aureus bacteraemia (SAB) are needed to unde..

Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus

Glen P Carter, Mark B Schultz, Sarah L Baines, Anders Goncalves da Silva, Helen Heffernan, Audrey Tiong, Peter H Pham, Ian R Monk, Timothy P Stinear, Benjamin P Howden, Deborah A Williamson

Journal article  |  2018  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak

Jason C Kwong, Courtney R Lane, Finn Romanes, Anders Goncalves da Silva, Marion Easton, Katie Cronin, Mary Jo Waters, Takehiro Tomita, Kerrie Stevens, Mark B Schultz, Sarah L Baines, Norelle L Sherry, Glen P Carter, Andre Mu, Michelle Sait, Susan A Ballard, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2018  |  PEERJ

A Supervised Statistical Learning Approach for Accurate Legionella pneumophila Source Attribution during Outbreaks

Andrew H Buultjens, Kyra YL Chua, Sarah L Baines, Jason Kwong, Wei Gao, Zoe Cutcher, Stuart Adcock, Susan Ballard, Mark B Schultz, Takehiro Tomita, Nela Subasinghe, Glen P Carter, Sacha J Pidot, Lucinda Franklin, Torsten Seemann, Anders Goncalves Da Silva, Benjamin P Howden, Timothy P Stinear

Journal article  |  2017  |  APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Methicillin Resistant Staphylococcus aureus Transmission in a Ghanaian Burn Unit: The Importance of Active Surveillance in Resource-Limited Settings

Nana Ama Amissah, Andrew H Buultjens, Anthony Ablordey, Lieke van Dam, Ampomah Opoku-Ware, Sarah L Baines, Dieter Bulach, Caitlin S Tetteh, Isaac Prah, Tjip S van der Werf, Alexander W Friedrich, Torsten Seemann, Jan Maarten van Dijl, Ymkje Stienstra, Timothy P Stinear, John W Rossen

Journal article  |  2017  |  Frontiers in Microbiology

Vancomycin-intermediate Staphylococcus aureus isolates are attenuated for virulence when compared with susceptible progenitors

DR Cameron, Y-H Lin, S Trouillet-Assant, V Tafani, X Kostoulias, E Mouhtouris, N Skinner, K Visvanathan, SL Baines, B Howden, IR Monk, F Laurent, TP Stinear, BP Howden, AY Peleg

Journal article  |  2017  |  Clinical Microbiology and Infection

Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana

Grace Kpeli, Andrew H Buultjens, Stefano Giulieri, Evelyn Owusu-Mireku, Samuel Y Aboagye, Sarah L Baines, Torsten Seemann, Dieter Bulach, Anders Goncalves da Silva, Ian R Monk, Benjamin P Howden, Gerd Pluschke, Dorothy Yeboah-Manu, Timothy Stinear

Journal article  |  2017  |  PEERJ

Genomic insights into a sustained national outbreak of Yersinia pseudotuberculosis.

Deborah A Williamson, Sarah L Baines, Glen Carter, Anders Gonçalves da Silva, Xiaoyun Ren, Jill Sherwood, Muriel Dufour, Mark B Schultz, Nigel P French, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2017  |  Genome Biol Evol

In 2014, a sustained outbreak of yersiniosis due to Yersinia pseudotuberculosis occurred across all major cities in New Zealand (N..

A phylogenomic framework for assessing the global emergence and evolution of clonal complex 398 methicillin-resistant Staphylococcus aureus

Anders Goncalves da Silva, Sarah L Baines, Glen P Carter, Helen Heffernan, Nigel P French, Xiaoyun Ren, Torsten Seemann, Dieter Bulach, Jason Kwong, Timothy P Stinear, Benjamin P Howden, Deborah A Williamson

Journal article  |  2017  |  Microbial Genomics

Genomic Insights into a Sustained National Outbreak of Yersinia pseudotuberculosis

Deborah A Williamson, Sarah L Baines, Glen P Carter, Anders Goncalves da silva, Xiaoyun Ren, Jill Sherwood, Muriel Dufour, Mark B Schultz, Nigel P French, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2016  |  Genome Biology and Evolution

Emergence of endemic MLST non-typeable vancomycin-resistant Enterococcus faecium

Glen P Carter, Andrew H Buultjens, Susan A Ballard, Sarah L Baines, Takehiro Tomita, Janet Strachan, Paul DR Johnson, John K Ferguson, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2016  |  Journal of Antimicrobial Chemotherapy

Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana.

G Kpeli, I Darko Otchere, A Lamelas, AL Buultjens, D Bulach, SL Baines, T Seemann, S Giulieri, Z Nakobu, SY Aboagye, E Owusu-Mireku, G Pluschke, TP Stinear, D Yeboah-Manu

Journal article  |  2016  |  New Microbes and New Infections

We have previously shown that secondary infections of Buruli ulcer wounds were frequently caused by Staphylococcus aureus. To gain..

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements

Sarah L Baines, Benjamin P Howden, Helen Heffernan, Timothy P Stinear, Glen P Carter, Torsten Seemann, Jason C Kwong, Stephen R Ritchie, Deborah A Williamson

Journal article  |  2016  |  Antimicrobial agents and chemotherapy

Heterogeneity of Genetic Pathways toward Daptomycin Nonsusceptibility in Staphylococcus aureus Determined by Adjunctive Antibiotics

Andrew D Berti, Sarah L Baines, Benjamin P Howden, George Sakoulas, Victor Nizet, Richard A Proctor, Warren E Rose

Journal article  |  2015  |  Antimicrobial Agents and Chemotherapy

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant Staphylococcus aureus

Sarah L Baines, Kathryn E Holt, Mark B Schultz, Torsten Seemann, Brian O Howden, Slade O Jensen, Sebastiaan J van Hal, Geoffrey W Coombs, Neville Firth, David R Powell, Timothy P Stinear, Benjamin P Howden

Journal article  |  2015  |  MBIO