Maria Kokkinos

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..

Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Maria Kokkinos, Patrick F James, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Molecular Human Reproduction

Ageing and parturition share common pathways, but their relationship remains poorly understood. Decidual cells undergo ageing as p..

Epithelial-mesenchymal transition during extravillous trophoblast differentiation

Jessica E Davies, Juergen Pollheimer, Hannah EJ Yong, Maria I Kokkinos, Bill Kalionis, Martin Knoefler, Padma Murthi

Journal article  |  2016  |  CELL ADHESION & MIGRATION

A successful pregnancy depends on the intricate and timely interactions of maternal and fetal cells. Placental extravillous cytotr..

Defining the E-Cadherin Repressor Interactome in Epithelial-Mesenchymal Transition: The PMC42 Model as a Case Study

Honor J Hugo, Maria I Kokkinos, Tony Blick, M Leigh Ackland, Erik W Thompson, Donald F Newgreen

Journal article  |  2011  |  CELLS TISSUES ORGANS

Epithelial-mesenchymal transition (EMT) is a feature of migratory cellular processes in all stages of life, including embryonic de..

Cadherins in the human placenta - epithelial-mesenchymal transition (EMT) and placental development

MI Kokkinos, P Murthi, R Wafai, EW Thompson, DP Newgreen

Journal article  |  2010  |  PLACENTA

Colonisation of the maternal uterine wall by the trophoblast involves a series of alterations in the behaviour and morphology of t..

A Novel Role for ac-FOX-O1 in Fetal Membrane Rupture

Maria Irene Kokkinos

Journal article  |  2009  |  REPRODUCTIVE SCIENCES

Differential requirement for beta-catenin in epithelial and fiber cells during lens development

Sarah Cain, Gemma Martinez, Maria I Kokkinos, Kirsty Turner, Robert J Richardson, Helen E Abud, Joerg Huelsken, Michael L Robinson, Robb U de Iongh

Journal article  |  2008  |  DEVELOPMENTAL BIOLOGY

Recent studies implicate Wnt/beta-catenin signaling in lens differentiation (Stump, R. J., et al., 2003. A role for Wnt/beta-caten..

Focal adhesion kinase (FAK) expression and activation during lens development

Maria I Kokkinos, Heidi J Brown, Robbert U de Iongh

Journal article  |  2007  |  MOLECULAR VISION

PURPOSE: Regulation of lens development involves an intricate interplay between growth factor (e.g. FGF and TGFbeta) and extracell..

Vimentin and epithelial-mesenchymal transition in human breast cancer - Observations in vitro and in vivo

Maria I Kokkinos, Razan Wafai, Meng Kang Wong, Donald F Newgreen, Erik W Thompson, Mark Waltham

Journal article  |  2007  |  CELLS TISSUES ORGANS

Breast cancer is a highly prevalent disease among women worldwide. While the expression of certain proteins within these tumours i..

BMP and activin receptor expression in lens development

R de Iongh, Y Chen, M Kokkinos, J McAvoy

Journal article  |  2004  |  MOLECULAR VISION

PURPOSE: Members of the TGFbeta super-family have been shown to play important roles in lens development, including lens placode f..