Haroon Naeem

Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.

Ailin Lepletier, Michael L Hun, Maree V Hammett, Kahlia Wong, Haroon Naeem, Mark Hedger, Kate Loveland, Ann P Chidgey

Journal article  |  2019  |  Cell Reports

A key feature of immune functional impairment with age is the progressive involution of thymic tissue responsible for naive T cell..

Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children

Line Hjort, David Martino, Louise Groth Grunnet, Haroon Naeem, Jovana Maksimovic, Anders Henrik Olsson, Cuilin Zhang, Charlotte Ling, Sjurdur Frodi Olsen, Richard Saffery, Allan Arthur Vaag

Journal article  |  2018  |  JCI Insight

Age-Related Decline in Primary CD8( ) T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8( ) T Cells

Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi HO Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov, Florian Wiede, Rosela Webster, Chantelle Blyth, Xavier YX Sng, Tony Tiganis, David Powell, Peter C Doherty, Stephen J Turner, Katherine Kedzierska, Nicole L La Gruta

Journal article  |  2018  |  Cell Reports

The use of targeted next generation sequencing to explore candidate regulators of TGF-β1's impact on kidney cells

B Wang, G Ji, H Naeem, J Wang, P Kantharidis, D Powell, SD Ricardo

Journal article  |  2018  |  Frontiers in Physiology

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribut..

Genome-Wide Measures of Peripheral Blood Dna Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study

Liesel M FitzGerald, Haroon Naeem, Enes Makalic, Daniel F Schmidt, James G Dowty, Jihoon E Joo, Chol-Hee Jung, Julie K Bassett, Pierre-Antoine Dugue, Jessica Chung, Andrew Lonie, Roger L Milne, Ee Ming Wong, John L Hopper, Dallas R English, Gianluca Severi, Laura Baglietto, John Pedersen, Graham G Giles, Melissa C Southey

Journal article  |  2017  |  The Prostate

A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance

Nikhil Sapre, Geoff Macintyre, Michael Clarkson, Haroon Naeem, Marek Cmero, Adam Kowalczyk, Paul D Anderson, Anthony J Costello, Niall M Corcoran, Christopher M Hovens

Journal article  |  2016  |  British Journal of Cancer

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

Matthew KH Hong, Geoff Macintyre, David C Wedge, Peter Van Loo, Keval Patel, Sebastian Lunke, Ludmil B Alexandrov, Clare Sloggett, Marek Cmero, Francesco Marass, Dana Tsui, Stefano Mangiola, Andrew Lonie, Haroon Naeem, Nikhil Sapre, Pramit M Phal, Natalie Kurganovs, Xiaowen Chin, Michael Kerger, Anne Y Warren, et al.

Journal article  |  2015  |  Nature Communications

Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

Haroon Naeem, Nicholas C Wong, Zac Chatterton, Matthew KH Hong, John S Pedersen, Niall M Corcoran, Christopher M Hovens, Geoff Macintyre

Journal article  |  2014  |  BMC Genomics

Rigorous assessment of gene set enrichment tests.

Haroon Naeem, Ralf Zimmer, Pegah Tavakkolkhah, Robert Küffner

Journal article  |  2012  |  Bioinformatics

MOTIVATION: Several statistical tests are available to detect the enrichment of differential expression in gene sets. Such tests w..

MIRTFnet: analysis of miRNA regulated transcription factors.

Haroon Naeem, Robert Küffner, Ralf Zimmer

Journal article  |  2011  |  PLoS One

BACKGROUND: Several expression datasets of miRNA transfection experiments are available to analyze the regulatory mechanisms downs..

miRSel: automated extraction of associations between microRNAs and genes from the biomedical literature.

Haroon Naeem, Robert Küffner, Gergely Csaba, Ralf Zimmer

Journal article  |  2010  |  BMC Bioinformatics

BACKGROUND: MicroRNAs have been discovered as important regulators of gene expression. To identify the target genes of microRNAs, ..