Dominic Hare

The Immuno-Mass Spectrometry Chemical Microscope

Dominic J Hare, Olga Shimoni, David P Bishop

Journal article  |  2020  |  Trends in Chemistry

Construction of 3D native elemental maps for large biological specimens using LA-ICP-MS coupled with X-ray tomography

Estephany Marillo-Sialer, Jay R Black, Bence Paul, Kai Kysenius, Peter J Crouch, Janet M Hergt, Jon D Woodhead, Dominic J Hare

Journal article  |  2020  |  Journal of Analytical Atomic Spectrometry

Integration of quantitative elemental distributions with structural information, allowing novel insights into how tissue developme..

Regional iron distribution and soluble ferroprotein profiles in the healthy human brain

Erin J McAllum, Dominic J Hare, Irene Volitakis, Catriona A McLean, Ashley I Bush, David I Finkelstein, Blaine R Roberts

Journal article  |  2020  |  Progress in Neurobiology

Iron is essential for brain development and health where its redox properties are used for a number of neurological processes. How..

Characterising the spatial and temporal brain metal profile in a mouse model of tauopathy

Shalini S Rao, Larissa Lago, Raquel Gonzalez de Vega, Lisa Bray, Dominic J Hare, David Clases, Philip A Doble, Paul A Adlard

Journal article  |  2020  |  Metallomics

A dysregulation in the homeostasis of metals such as copper, iron and zinc is speculated to be involved in the pathogenesis of tau..

Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine

AL Heffernan, MJ Gomez-Ramos, C Symeonides, DJ Hare, S Vijayasarathy, K Thompson, JF Mueller, AL Ponsonby, PD Sly

Journal article  |  2020  |  Chemosphere

There is an interdisciplinary interface between analytical chemistry and epidemiology studies with respect to the design, executio..

Meta-analysis of copper and iron in Parkinson's disease brain and biofluids

Sian Genoud, Alistair M Senior, Dominic J Hare, Kay L Double

Journal article  |  2019  |  Movement Disorders

Health outcomes of iron supplementation and/or food fortification in iron-replete children aged 4-24 months: protocol for a systematic review and meta-analysis

Dominic J Hare, Sabine Braat, Barbara R Cardoso, Christopher Morgan, Ewa A Szymlek-Gay, Beverley-Ann Biggs

Journal article  |  2019  |  Systematic Reviews

BACKGROUND: Direct supplementation or food fortification with iron are two public health initiatives intended to reduce the preval..

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

Benjamin G Trist, Dominic J Hare, Kay L Double

Journal article  |  2019  |  Aging Cell

Perineuronal Nets: Plasticity, Protection, and Therapeutic Potential

Amy C Reicheft, Dominic J Hare, Timothy J Bussey, Lisa M Saksida

Journal article  |  2019  |  Trends in Neurosciences

L-3,4-dihydroxyphenylalanine (L-DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson's disease

Jessica L Billings, Sarah L Gordon, Tristan Rawling, Philip A Doble, Ashley I Bush, Paul A Adlard, David I Finkelstein, Dominic J Hare

Journal article  |  2019  |  Journal of Neurochemistry

From niche methods to necessary tools: The growing importance of analytical atomic spectrometry in metal imaging in neuroscience

Erin J McAllum, Dominic J Hare

Journal article  |  2019  |  Spectrochimica Acta Part B: Atomic Spectroscopy

A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and parvalbumin interneuron depletion in the medial prefrontal cortex

Amy C Reichelt, Gabrielle D Gibson, Kirsten N Abbott, Dominic J Hare

Journal article  |  2019  |  Food & Function

Simultaneous nanostructure and chemical imaging of intact whole nematodes

Michael WM Jones, Nicholas W Phillips, Brian Abbey, Dominic J Hare, Grant A van Riessen, David J Vine, Martin D de Jonge, Gawain McColl

Journal article  |  2019  |  Chemical Communications

Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease

Barbara R Cardoso, Blaine R Roberts, Charles B Malpas, Lucy Vivash, Sila Genc, Michael M Saling, Patricia Desmond, Christopher Steward, Rodney J Hicks, Jason Callahan, Amy Brodtmann, Steven Collins, Stephen Macfarlane, Niall M Corcoran, Christopher M Hovens, Dennis Velakoulis, Terence J O'Brien, Dominic J Hare, Ashley I Bush

Journal article  |  2019  |  Neurotherapeutics

A versatile quantitative microdroplet elemental imaging method optimised for integration in biochemical workflows for low-volume samples

Kai Kysenius, Bence Paul, James B Hilton, Jeffrey R Liddell, Dominic J Hare, Peter J Crouch

Journal article  |  2019  |  Analytical and Bioanalytical Chemistry

Anatomical redistribution of endogenous copper in embryonic mice overexpressing SOD1

K Kysenius, JB Hilton, B Paul, DJ Hare, PJ Crouch

Journal article  |  2019  |  Metallomics

Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease

Yingying Sun, A Ninh Pham, Dominic J Hare, T David Waite

Journal article  |  2018  |  Frontiers in Neuroscience

Tracing Environmental Exposure from Neurodevelopment to Neurodegeneration

Amy L Heffernan, Dominic J Hare

Journal article  |  2018  |  Trends in Neurosciences

A Proposed Mechanism for Neurodegeneration in Movement Disorders Characterized by Metal Dyshomeostasis and Oxidative Stress

Benjamin Guy Trist, Dominic James Hare, Kay Lorraine Double

Journal article  |  2018  |  Cell Chemical Biology

Applications of liquid chromatography-inductively coupled plasma-mass spectrometry in the biosciences: A tutorial review and recent developments

David P Bishop, Dominic J Hare, David Clases, Philip A Doble

Journal article  |  2018  |  TrAC Trends in Analytical Chemistry

A guide to integrating immunohistochemistry and chemical imaging

David P Bishop, Nerida Cole, Tracy Zhang, Philip A Doble, Dominic J Hare

Journal article  |  2018  |  Chemical Society Reviews

Trehalose elevates brain zinc levels following controlled cortical impact in a mouse model of traumatic brain injury

Stuart D Portbury, Dominic J Hare, David P Bishop, David I Finkelstein, Philip A Doble, Paul A Adlard

Journal article  |  2018  |  Metallomics

Neurological effects of iron supplementation in infancy: finding the balance between health and harm in iron-replete infants

Dominic J Hare, Barbara Rita Cardoso, Ewa A Szymlek-Gay, Beverley-Ann Biggs

Journal article  |  2018  |  The Lancet Child & Adolescent Health

Promises and Pitfalls of Metal Imaging in Biology

Elizabeth J New, Verena C Wimmer, Dominic J Hare

Journal article  |  2018  |  Cell Chemical Biology

Accumulation of dysfunctional SOD1 protein in Parkinson's disease is not associated with mutations in the SOD1 gene

Benjamin G Trist, Jennifer A Fifita, Sarah E Freckleton, Dominic J Hare, Simon JG Lewis, Glenda M Halliday, Ian P Blair, Kay L Double

Journal article  |  2018  |  Acta Neuropathologica

Radiation Dose Limits for Bioanalytical X-ray Fluorescence Microscopy

Michael WM Jones, Dominic J Hare, Simon A James, Martin D de Jonge, Gawain McColl

Journal article  |  2017  |  Analytical Chemistry

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain

Sian Genoud, Blaine R Roberts, Adam P Gunn, Glenda M Halliday, Simon JG Lewis, Helen J Ball, Dominic J Hare, Kay L Double

Journal article  |  2017  |  Metallomics

Trehalose improves traumatic brain injury-induced cognitive impairment

Stuart D Portbury, Dominic J Hare, David I Finkelstein, Paul A Adlard

Journal article  |  2017  |  PLOS ONE

Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson's disease brain

Benjamin G Trist, Katherine M Davies, Veronica Cottam, Sian Genoud, Richard Ortega, Stephane Roudeau, Asuncion Carmona, Kasun De Silva, Valerie Wasinger, Simon JG Lewis, Perminder Sachdev, Bradley Smith, Claire Troakes, Caroline Vance, Christopher Shaw, Safa Al-Sarraj, Helen J Ball, Glenda M Halliday, Dominic J Hare, Kay L Double

Journal article  |  2017  |  Acta Neuropathologica

The APOE epsilon 4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease

Barbara R Cardoso, Dominic J Hare, Monica Lind, Catriona A McLean, Irene Volitakis, Simon M Laws, Colin L Masters, Ashley I Bush, Blaine R Roberts

Journal article  |  2017  |  ACS Chemical Neuroscience

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease

David I Finkelstein, Jessica L Billings, Paul A Adlard, Scott Ayton, Amelia Sedjahtera, Colin L Masters, Simon Wilkins, David M Shackleford, Susan A Charman, Wojciech Bal, Izabela A Zawisza, Ewa Kurowska, Andrew L Gundlach, Sheri Ma, Ashley I Bush, Dominic J Hare, Philip A Doble, Simon Crawford, Elisabeth CL Gautier, Jack Parsons, et al.

Journal article  |  2017  |  Acta Neuropathologica Communications

Commentary: Comments regarding Becker et al. (Analytica Chimica Acta, 835, 2014, 1-18)

Dominic J Hare

Journal article  |  2017  |  Analytica Chimica Acta

Hepcidin: a real-time biomarker of iron need

Dominic J Hare

Journal article  |  2017  |  Metallomics

Whole-brain metallomic analysis of the common marmoset (Callithrix jacchus)

B Knauer, P Majka, KJ Watkins, AWR Taylor, D Malamanova, B Paul, Hsin-Hao Yu, AI Bush, DJ Hare, DH Reser

Journal article  |  2017  |  Metallomics

Direct determination of zinc in plasma by graphite furnace atomic absorption spectrometry using palladium/magnesium and EDTA matrix modification with high temperature pyrolysis

Brian J Stevens, Dominic J Hare, Irene Volitakis, Robert A Cherny, Blaine R Roberts

Journal article  |  2017  |  Journal of Analytical Atomic Spectrometry

Age modulates the injury-induced metallomic profile in the brain

Stuart D Portbury, Dominic J Hare, Charlotte J Sgambelloni, David P Bishop, David I Finkelstein, Philip A Doble, Paul A Adlard

Journal article  |  2017  |  Metallomics

Imaging metals in biology: pictures of metals in health and disease

Dominic J Hare, Elizabeth J New, Gawain McColl

Journal article  |  2017  |  Metallomics

Iron, Copper, and Zinc Concentration in A beta Plaques in the APP/PS1 Mouse Model of Alzheimer's Disease Correlates with Metal Levels in the Surrounding Neuropil

Simon A James, Quentin I Churches, Martin D de Jonge, Ian E Birchall, Victor Streltsov, Gawain McColl, Paul A Adlard, Dominic J Hare

Journal article  |  2017  |  ACS Chemical Neuroscience

Glutathione peroxidase 4: a new player in neurodegeneration?

BR Cardoso, DJ Hare, AI Bush, BR Roberts

Journal article  |  2017  |  Molecular Psychiatry

Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson's disease

Dominic J Hare, Barbara Rita Cardoso, Erika P Raven, Kay L Double, David I Finkelstein, Ewa A Szymlek-Gay, Beverley-Ann Biggs

Journal article  |  2017  |  npj Parkinsons Disease

Imaging Metals in the Brain by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry

Dominic J Hare, Bence Paul, Philip A Doble

Book Chapter  |  2017  |  Neuromethods

The Role of Selenium in Neurodegenerative Diseases

Barbara R Cardoso, Dominic J Hare, Ashley I Bush

Book Chapter  |  2017

Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease

Stuart D Portbury, Dominic J Hare, Charlotte Sgambelloni, Kali Perronnes, Ashley J Portbury, David I Finkelstein, Paul A Adlard

Journal article  |  2017  |  Journal of Alzheimer's Disease

Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL)

Barbara R Cardoso, Dominic J Hare, Ashley I Bush, Qiao-Xin Li, Christopher J Fowler, Colin L Masters, Ralph N Martins, Katherine Ganio, Amber Lothian, Soumya Mukherjee, Eugene A Kapp, Blaine R Roberts

Journal article  |  2017  |  Journal of Alzheimer's Disease

Imaging Metals in Brain Tissue by Laser Ablation - Inductively Coupled Plasma - Mass Spectrometry (LA-ICP-MS)

Dominic J Hare, Kai Kysenius, Bence Paul, Beate Knauer, Robert W Hutchinson, Ciaran O'Connor, Fred Fryer, Tom P Hennessey, Ashley I Bush, Peter J Crouch, Philip A Doble

Journal article  |  2017  |  Journal of Visualized Experiments

GPX1 Pro198Leu polymorphism and GSTM1 deletion do not affect selenium and mercury status in mildly exposed Amazonian women in an urban population

Ariana V Rocha, Barbara Rita Cardoso, Bruna Zavarize, Kaluce Almondes, Isabella Bordon, Dominic J Hare, Deborah Ines Teixeira Favaro, Silvia Maria Franciscato Cozzolino

Journal article  |  2016  |  Science of The Total Environment

Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid

Blaine R Roberts, James D Doecke, Alan Rembach, L Fernanda Yevenes, Christopher J Fowler, Catriona A McLean, Monica Lind, Irene Volitakis, Colin L Masters, Ashley I Bush, Dominic J Hare

Journal article  |  2016  |  Acta Neuropathologica Communications

Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex

Dominic J Hare, Erika P Raven, Blaine R Roberts, Mirjana Bogeski, Stuart D Portbury, Catriona A McLean, Colin L Masters, James R Connor, Ashley I Bush, Peter J Crouch, Philip A Doble

Journal article  |  2016  |  NeuroImage

Iron and dopamine: a toxic couple

Dominic J Hare, Kay L Double

Journal article  |  2016  |  Brain

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

Jessica L Billings, Dominic J Hare, Milawaty Nurjono, Irene Volitakis, Robert A Cherny, Ashley I Bush, Paul A Adlard, David I Finkelstein

Journal article  |  2016  |  ACS Chemical Neuroscience

phi XANES: In vivo imaging of metal-protein coordination environments

Simon A James, Dominic J Hare, Nicole L Jenkins, Martin D de Jonge, Ashley I Bush, Gawain McColl

Journal article  |  2016  |  Scientific Reports

Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice

DI Finkelstein, DJ Hare, JL Billings, A Sedjahtera, M Nurjono, E Arthofer, S George, JG Culvenor, AI Bush, PA Adlard

Journal article  |  2016  |  ACS Chemical Neuroscience

Elemental imaging of leaves from the metal hyperaccumulating plant Noccaea caerulescens shows different spatial distribution of Ni, Zn and Cd

Damien L Callahan, Dominic J Hare, David P Bishop, Philip A Doble, Ute Roessner

Journal article  |  2016  |  RSC Advances

Elemental bio-imaging using laser ablation-triple quadrupole-ICP-MS

David P Bishop, David Clases, Fred Fryer, Elizabeth Williams, Simon Wilkins, Dominic J Hare, Nerida Cole, Uwe Karst, Philip A Doble

Journal article  |  2016  |  Journal of Analytical Atomic Spectrometry

A time-course analysis of changes in cerebral metal levels following a controlled cortical impact

Stuart D Portbury, Dominic J Hare, Charlotte Sgambelloni, David I Finkelstein, Paul A Adlard

Journal article  |  2016  |  Metallomics

Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake

Barbara R Cardoso, Alexandre L Busse, Dominic J Hare, Cristiane Cominetti, Maria A Horst, Gawain McColl, Regina M Magaldi, Wilson Jacob-Filho, Silvia MF Cozzolino

Journal article  |  2016  |  Food & Function

Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice

David I Finkelstein, Dominic J Hare, Jessica L Billings, Amelia Sedjahtera, Milawaty Nurjono, Elisa Arthofer, Sonia George, Janetta G Culvenor, Ashley I Bush, Paul A Adlard

Journal article  |  2016  |  ACS chemical neuroscience

Characterisation of matrix-based polyatomic interference formation in laser ablation-inductively coupled plasma-mass spectrometry using dried micro-droplet ablation and its relevance for bioimaging

Dominic J Hare, Fred Fryer, Bence Paul, David P Bishop, Philip A Doble

Journal article  |  2016  |  Analytical Methods

On the outside looking in: redefining the role of analytical chemistry in the biosciences

Dominic J Hare, Elizabeth J New

Journal article  |  2016  |  Chemical Communications

Profiling changes to natively-bound metals during Caenorhabditis elegans development

Dominic J Hare, Blaine R Roberts, Gawain McColl

Journal article  |  2016  |  RSC Advances

Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing

Dominic J Hare, Noel G Faux, Blaine R Roberts, Irene Volitakis, Ralph N Martins, Ashley I Bush

Journal article  |  2016  |  Metallomics

High-resolution complementary chemical imaging of bio-elements in Caenorhabditis elegans

Dominic J Hare, Michael WM Jones, Verena C Wimmer, Nicole L Jenkins, Martin D de Jonge, Ashley I Bush, Gawain McColl

Journal article  |  2016  |  Metallomics

The Emerging Role of Metalloproteomics in Alzheimer's Disease Research

Dominic J Hare, Alan Rembach, Blaine R Roberts

Journal article  |  2016  |  Methods in Molecular Biology

Accurate biometal quantification per individual Caenorhabditis elegans

Katherine Ganio, Simon A James, Dominic J Hare, Blaine R Roberts, Gawain McColl

Journal article  |  2016  |  The Analyst

Selenium status in preschool children receiving a Brazil nut-enriched diet

Irland BG Martens, Barbara R Cardoso, Dominic J Hare, Megan M Niedzwiecki, Franco M Lajolo, Andreas Martens, Silvia MF Cozzolino

Journal article  |  2015  |  Nutrition

Is early-life iron exposure critical in neurodegeneration?

Dominic J Hare, Manish Arora, Nicole L Jenkins, David I Finkelstein, Philip A Doble, Ashley I Bush

Journal article  |  2015  |  Nature Reviews Neurology

Metal chaperones prevent zinc-mediated cognitive decline

Paul A Adlard, Jacqui Parncutt, Varsha Lal, Simon James, Dominic Hare, Philip Doble, David I Finkelstein, Ashley I Bush

Journal article  |  2015  |  Neurobiology of Disease

Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy

Katherine M Davies, Dominic J Hare, Sylvain Bohic, Simon A James, Jessica L Billings, David I Finkelstein, Philip A Doble, Kay L Double

Journal article  |  2015  |  Analytical Chemistry

Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA

Hye Rim Cho, Youkyung Lee, Philip Doble, David Bishop, Dominic Hare, Young-Jae Kim, Kwang Gi Kim, Hye Seung Jung, Kyong Soo Park, Seung Hong Choi, Woo Kyung Moon

Journal article  |  2015  |  World Journal of Gastroenterology

Decreased Plasma Iron in Alzheimer's Disease Is Due to Transferrin Desatu ration

Dominic J Hare, James D Doecke, Noel G Faux, Alan Rembach, Irene Volitakis, Christopher J Fowler, Rudolf Grimm, Philip A Doble, Robert A Cherny, Colin L Masters, Ashley I Bush, Blame R Roberts

Journal article  |  2015  |  ACS Chemical Neuroscience

Parkinson's Disease Iron Deposition Caused by Nitric Oxide-Induced Loss of beta-Amyloid Precursor Protein

Scott Ayton, Peng Lei, Dominic J Hare, James A Duce, Jessica L George, Paul A Adlard, Catriona McLean, Jack T Rogers, Robert A Cherny, David I Finkelstein, Ashley I Bush

Journal article  |  2015  |  Journal of Neuroscience

Stabilization of Nontoxic A beta-Oligomers: Insights into the Mechanism of Action of Hydroxyquinolines in Alzheimer's Disease

Timothy M Ryan, Blaine R Roberts, Gawain McColl, Dominic J Hare, Philip A Doble, Qiao-Xin Li, Monica Lind, Anne M Roberts, Haydyn DT Mertens, Nigel Kirby, Chi LL Pham, Mark G Hinds, Paul A Adlard, Kevin J Barnham, Cyril C Curtain, Colin L Masters

Journal article  |  2015  |  Journal of Neuroscience

Selenium, selenoproteins and neurodegenerative diseases

Barbara Rita Cardoso, Blaine R Roberts, Ashley I Bush, Dominic J Hare

Journal article  |  2015  |  Metallomics

Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution

Dominic J Hare, Elizabeth J New, Martin D de Jonge, Gawain McColl

Journal article  |  2015  |  Chemical Society Reviews

Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans

Simon A James, Blaine R Roberts, Dominic J Hare, Martin D de Jonge, Ian E Birchall, Nicole L Jenkins, Robert A Cherny, Ashley I Bush, Gawain McColl

Journal article  |  2015  |  Chemical Science

Determination of selenium in serum in the presence of gadolinium with ICP-QQQ-MS

David P Bishop, Dominic J Hare, Fred Fryer, Regina V Taudte, Barbara R Cardoso, Nerida Cole, Philip A Doble

Journal article  |  2015  |  The Analyst

Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging (vol 6, pg 5383, 2015)

Bence Paul, Dominic J Hare, David P Bishop, Chad Paton, Tran Nguyen Van, Nerida Cole, Megan M Niedzwiecki, Erica Andreozzi, Angela Vais, Jessica L Billings, Lisa Bray, Ashley I Bush, Gawain McColl, Blaine R Roberts, Paul A Adlard, David I Finkelstein, John Hellstrom, Janet M Hergt, Jon D Woodhead, Philip A Doble

Journal article  |  2015  |  Chemical Science

Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging

Bence Paul, Dominic J Hare, David P Bishop, Chad Paton, Tran Nguyen Van, Nerida Cole, Megan M Niedwiecki, Erica Andreozzi, Angela Vais, Jessica L Billings, Lisa Bray, Ashley I Bush, Gawain McColl, Blaine R Roberts, Paul A Adlard, David I Finkelstein, John Hellstrom, Janet M Hergt, Jon D Woodhead, Philip A Doble

Journal article  |  2015  |  Chemical Science

Tooth lead levels as an estimate of lead body burden in rats following pre- and neonatal exposure

Manish Arora, Dominic J Hare

Journal article  |  2015  |  RSC Advances

Traumatic brain injury induces elevation of Co in the human brain

Blaine R Roberts, Dominic J Hare, Catriona A McLean, Alison Conquest, Monica Lind, Qiao-Xin Li, Ashley I Bush, Colin L Masters, Maria-Christina Morganti-Kossmann, Tony Frugier

Journal article  |  2015  |  Metallomics

Speciation and quantification of organotin compounds in sediment and drinking water by isotope dilution liquid chromatography-inductively coupled plasma-mass spectrometry

David P Bishop, Dominic J Hare, Adrian de Grazia, Fred Fryer, Philip A Doble

Journal article  |  2015  |  Analytical Methods

Beyond the transect: An alternative microchemical imaging method for fine scale analysis of trace elements in fish otoliths during early life

Nicole McGowan, Ashley M Fowler, Kerryn Parkinson, David P Bishop, Katherine Ganio, Philip A Doble, David J Booth, Dominic J Hare

Journal article  |  2014  |  Science of The Total Environment

Malignant Glioma: MR Imaging by Using 5-Aminolevulinic Acid in an Animal Model

Hye Rim Cho, Dong Hyun Kim, Daehong Kim, Philip Doble, David Bishop, Dominic Hare, Chul-Kee Park, Woo Kyung Moon, Moon Hee Han, Seung Hong Choi

Journal article  |  2014  |  Radiology

Oral Treatment with Cu-II(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Blaine R Roberts, Nastasia KH Lim, Erin J McAllum, Paul S Donnelly, Dominic J Hare, Philip A Doble, Bradley J Turner, Katherine A Price, Sin Chun Lim, Brett M Paterson, James L Hickey, Timothy W Rhoads, Jared R Williams, Katja M Kanninen, Lin W Hung, Jeffrey R Liddell, Alexandra Grubman, Jean-Francois Monty, Roxana M Llanos, David R Kramer, et al.

Journal article  |  2014  |  Journal of Neuroscience

Copper pathology in vulnerable brain regions in Parkinson's disease

Katherine M Davies, Sylvain Bohic, Asuncion Carmona, Richard Ortega, Veronica Cottam, Dominic J Hare, John PM Finberg, Stefanie Reyes, Glenda M Halliday, Julian FB Mercer, Kay L Double

Journal article  |  2014  |  Neurobiology of Aging

The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue

Dominic J Hare, Jessica L George, Lisa Bray, Irene Volitakis, Angela Vais, Timothy M Ryan, Robert A Cherny, Ashley I Bush, Colin L Masters, Paul A Adlard, Philip A Doble, David I Finkelstein

Journal article  |  2014  |  Journal of Analytical Atomic Spectrometry

An iron-dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Dominic J Hare, Peng Lei, Scott Ayton, Blaine R Roberts, Rudolf Grimm, Jessica L George, David P Bishop, Alison D Beavis, Sarah J Donovan, Gawain McColl, Irene Volitakis, Colin L Masters, Paul A Adlard, Robert A Cherny, Ashley I Bush, David I Finkelstein, Philip A Doble

Journal article  |  2014  |  Chemical Science

Decreased serum zinc is an effect of ageing and not Alzheimer's disease

Alan Rembach, Dominic J Hare, James D Doecke, Samantha C Burnham, Irene Volitakis, Christopher J Fowler, Robert A Cherny, Catriona McLean, Rudolf Grimm, Ralph Martins, David Ames, Colin L Masters, Ashley I Bush, Blaine R Roberts

Journal article  |  2014  |  Metallomics: integrated biometal science

Long-Term Intermittent Hypoxia Elevates Cobalt Levels in the Brain and Injures White Matter in Adult Mice

Sigrid C Veasey, Jessica Lear, Yan Zhu, Judith B Grinspan, Dominic J Hare, SiHe Wang, Dustin Bunch, Philip A Doble, Stephen R Robinson

Journal article  |  2013  |  Sleep

A delicate balance: Iron metabolism and diseases of the brain

Dominic Hare, Scott Ayton, Ashley Bush, Peng Lei

Journal article  |  2013  |  Frontiers in Aging Neuroscience

Barium distributions in teeth reveal early-life dietary transitions in primates

Christine Austin, Tanya M Smith, Asa Bradman, Katie Hinde, Renaud Joannes-Boyau, David Bishop, Dominic J Hare, Philip Doble, Brenda Eskenazi, Manish Arora

Journal article  |  2013  |  Nature

In Vivo Study of Spherical Gold Nanoparticles: Inflammatory Effects and Distribution in Mice

Hui Chen, Alisha Dorrigan, Sonia Saad, Dominic J Hare, Michael B Cortie, Stella M Valenzuela

Journal article  |  2013  |  PLoS ONE

Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

Dominic J Hare, Paul A Adlard, Philip A Doble, David I Finkelstein

Journal article  |  2013  |  Metallomics: integrated biometal science

Protocol for production of matrix-matched brain tissue standards for imaging by laser ablation-inductively coupled plasma-mass spectrometry

Dominic J Hare, Jessica Lear, David Bishop, Alison Beavis, Philip A Doble

Journal article  |  2013  |  Analytical Methods

Localization of copper and copper transporters in the human brain

Katherine M Davies, Dominic J Hare, Veronica Cottam, Nicholas Chen, Leon Hilgers, Glenda Halliday, Julian FB Mercer, Kay L Double

Journal article  |  2013  |  Metallomics

Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction.

Alan Rembach, Dominic J Hare, Monica Lind, Christopher J Fowler, Robert A Cherny, Catriona McLean, Ashley I Bush, Colin L Masters, Blaine R Roberts

Journal article  |  2013  |  International Journal of Alzheimer's Disease

Alzheimer's disease (AD) is the leading cause of dementia and represents a significant burden on the global economy and society. T..

Considerations for measuring iron in post-mortem tissue of Parkinson's disease patients

Dominic J Hare, Manfred Gerlach, Peter Riederer

Journal article  |  2012  |  Journal of Neural Transmission

Spatially resolved imaging methods to probe metals in the brain: From subcellular to organ level

S Bohic, D Hare, A Daoust, P Cloetens, EL Barbier

Book Chapter  |  2012

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

Dominic Hare, Christine Austin, Philip Doble

Journal article  |  2012  |  The Analyst

Improving acquisition times of elemental bio-imaging for quadrupole-based LA-ICP-MS

Jessica Lear, Dominc Hare, Paul Adlard, David Finkelstein, Philip Doble

Journal article  |  2012  |  Journal of Analytical Atomic Spectrometry

Elemental bio-imaging of trace elements in teeth using laser ablation-inductively coupled plasma-mass spectrometry

Dominic Hare, Christine Austin, Philip Doble, Manish Arora

Journal article  |  2011  |  Journal of Dentistry

Spatial distribution of manganese in enamel and coronal dentine of human primary teeth

Manish Arora, Dominic Hare, Christine Austin, Donald R Smith, Philip Doble

Journal article  |  2011  |  Science of The Total Environment

Factors affecting internal standard selection for quantitative elemental bio-imaging of soft tissues by LA-ICP-MS

Christine Austin, Fred Fryer, Jessica Lear, David Bishop, Dominic Hare, Tristan Rawling, Les Kirkup, Andrew McDonagh, Philip Doble

Journal article  |  2011  |  Journal of Analytical Atomic Spectrometry

Elemental Bio-imaging of Thorium, Uranium, and Plutonium in Tissues from Occupationally Exposed Former Nuclear Workers

Dominic Hare, Sergei Tolmachev, Anthony James, David Bishop, Christine Austin, Fred Fryer, Philip Doble

Journal article  |  2010  |  Analytical Chemistry

Quantification method for elemental bio-imaging by LA-ICP-MS using metal spiked PMMA films

Christine Austin, Dominic Hare, Tristan Rawling, Andrew M McDonagh, Philip Doble

Journal article  |  2010  |  Journal of Analytical Atomic Spectrometry

Thin Films of Ruthenium Phthalocyanine Complexes

Tristan Rawling, Christine E Austin, Dominic Hare, Philip A Doble, Hadi M Zareie, Andrew M McDonagh

Journal article  |  2009  |  Nano Research

Elemental bio-imaging of melanoma in lymph node biopsies.

Dominic Hare, Fiona Burger, Christine Austin, Fred Fryer, Rudolf Grimm, Brian Reedy, Richard A Scolyer, John F Thompson, Philip Doble

Journal article  |  2009  |  The Analyst

The spatial distribution of trace elements in human lymph nodes partially infiltrated by melanoma cells was determined by elementa..

Elemental bio-imaging of calcium phosphate crystal deposits in knee samples from arthritic patients

Christine Austin, Dominic Hare, Andrew L Rozelle, William H Robinson, Rudolf Grimm, Philip Doble

Journal article  |  2009  |  Metallomics

The answer is elemental

D Hare, D Bishop, C Austin, P Doble

Journal article  |  2009  |  Biochemist