Dominic Hare

Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic

Benjamin G Trist, James B Hilton, Dominic J Hare, Peter J Crouch, Kay L Double

Journal article  |  2020  |  Angewandte Chemie International Edition

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide breakdown and is important for most form..

Sex-dependent association between selenium status and cognitive performance in older adults

Barbara R Cardoso, Dominic J Hare, Helen Macpherson

Journal article  |  2020  |  European Journal of Nutrition

Simultaneous structural and elemental nano-imaging of human brain tissue

Sian Genoud, Michael WM Jones, Benjamin Guy Trist, Junjing Deng, Si Chen, Dominic James Hare, Kay L Double

Journal article  |  2020  |  Chemical Science

Structural and chemical characterisation of microfeatures in unadulterated Parkinson's disease brain tissue using synchrotron nano..

The Immuno-Mass Spectrometry Chemical Microscope

Dominic J Hare, Olga Shimoni, David P Bishop

Journal article  |  2020  |  Trends in Chemistry

Construction of 3D native elemental maps for large biological specimens using LA-ICP-MS coupled with X-ray tomography

Estephany Marillo-Sialer, Jay R Black, Bence Paul, Kai Kysenius, Peter J Crouch, Janet M Hergt, Jon D Woodhead, Dominic J Hare

Journal article  |  2020  |  Journal of Analytical Atomic Spectrometry

Integration of quantitative elemental distributions with structural information, allowing novel insights into how tissue developme..

Regional iron distribution and soluble ferroprotein profiles in the healthy human brain

Erin J McAllum, Dominic J Hare, Irene Volitakis, Catriona A McLean, Ashley I Bush, David I Finkelstein, Blaine R Roberts

Journal article  |  2020  |  Progress in Neurobiology

Iron is essential for brain development and health where its redox properties are used for a number of neurological processes. How..

Characterising the spatial and temporal brain metal profile in a mouse model of tauopathy

Shalini S Rao, Larissa Lago, Raquel Gonzalez de Vega, Lisa Bray, Dominic J Hare, David Clases, Philip A Doble, Paul A Adlard

Journal article  |  2020  |  Metallomics

A dysregulation in the homeostasis of metals such as copper, iron and zinc is speculated to be involved in the pathogenesis of tau..

Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine

AL Heffernan, MJ Gomez-Ramos, C Symeonides, DJ Hare, S Vijayasarathy, K Thompson, JF Mueller, AL Ponsonby, PD Sly

Journal article  |  2020  |  Chemosphere

There is an interdisciplinary interface between analytical chemistry and epidemiology studies with respect to the design, executio..

Meta-analysis of copper and iron in Parkinson's disease brain and biofluids

Sian Genoud, Alistair M Senior, Dominic J Hare, Kay L Double

Journal article  |  2019  |  Movement Disorders

Health outcomes of iron supplementation and/or food fortification in iron-replete children aged 4-24 months: protocol for a systematic review and meta-analysis

Dominic J Hare, Sabine Braat, Barbara R Cardoso, Christopher Morgan, Ewa A Szymlek-Gay, Beverley-Ann Biggs

Journal article  |  2019  |  Systematic Reviews

BACKGROUND: Direct supplementation or food fortification with iron are two public health initiatives intended to reduce the preval..