Olga Martin

Cancer Radiotherapy: Understanding the Price of Tumor Eradication

Olga A Martin, Roger F Martin

Journal article  |  2020  |  Frontiers in Cell and Developmental Biology

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation

Pavel N Lobachevsky, Jessica Ventura, Lina Giannakandropoulou, Helen Forrester, Jason S Palazzolo, Nicole M Haynes, Andrew W Stevenson, Christopher J Hall, Joel Mason, Gerasimos Pollakis, Ioannis S Pateras, Vassilis Gorgoulis, Georgia I Terzoudi, John A Hamilton, Carl N Sprung, Alexandros G Georgakilas, Olga A Martin

Journal article  |  2019  |  International Journal of Radiation Oncology*Biology*Physics

Systemic effects of synchrotron radiation

J Ventura, CN Sprung, HB Forrester, JS Palazzolo, A Ivashkevich, AW Stevenson, CJ Hall, AG Georgakilas, PN Lobachevsky, OA Martin

Conference Proceedings  |  2019  |  Journal of Physics: Conference Series

Radiation Therapy Modulates DNA Repair Efficiency in Peripheral Blood Mononuclear Cells of Patients With Non-Small Cell Lung Cancer

Xiaoyu Yin, Joel Mason, Pavel N Lobachevsky, Laura Munforte, Lisa Selbie, David L Ball, Roger F Martin, Trevor Leong, Shankar Siva, Olga A Martin

Journal article  |  2019  |  International Journal of Radiation Oncology*Biology*Physics

A Bayesian Approach for Prediction of Patient Radiosensitivity

Alan Herschtal, Roger F Martin, Trevor Leong, Pavel Lobachevsky, Olga A Martin

Journal article  |  2018  |  International Journal of Radiation Oncology*Biology*Physics

Localized synchrotron radiation in mice induces persistent systemic genotoxic events mediated by the functional immune system

Jessica Ventura, Pavel Lobachevsky, Jason Palazzolo, Helen Forrester, Nicole Haynes, Alesia Ivashkevich, Andrew Stevenson, Christopher Hall, Vassilis Gorgoulis, John Hamilton, Alexandros Georgakilas, Calr Sprung, Olga A Martin

Conference Proceedings  |  2018  |  Clinical Research (Excluding Clinical Trials)

Editorial: Therapy-induced metastasis

Olga A Martin, Robin L Anderson

Journal article  |  2018  |  Clinical & Experimental Metastasis

Radiation therapy-induced metastasis: radiobiology and clinical implications

Benjamin J Blyth, Aidan J Cole, Michael P MacManus, Olga A Martin

Journal article  |  2018  |  Clinical & Experimental Metastasis

Treatment for non-small-cell lung cancer and circulating tumor cells

Joel Mason, Benjamin Blyth, Michael P MacManus, Olga A Martin

Journal article  |  2017  |  Lung Cancer Management

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses

Jessica Ventura, Pavel N Lobachevsky, Jason S Palazzolo, Helen Forrester, Nicole M Haynes, Alesia Ivashkevich, Andrew W Stevenson, Christopher J Hall, Andreas Ntargaras, Vasilis Kotsaris, Gerasimos Ch Pollakis, Gianna Potsi, Konstantinos Skordylis, Georgia Terzoudi, Ioannis S Pateras, Vassilis G Gorgoulis, Alexandros G Georgakilas, Carl N Sprung, Olga A Martin

Journal article  |  2017  |  Cancer Research

Clinical and Functional Assays of Radiosensitivity and Radiation-Induced Second Cancer

Mohammad Habash, Luis C Bohorquez, Elizabeth Kyriakou, Tomas Kron, Olga A Martin, Benjamin J Blyth

Journal article  |  2017  |  Cancers

p21: A Two-Faced Genome Guardian

Alexandros G Georgakilas, Olga A Martin, William M Bonner

Journal article  |  2017  |  Trends in Molecular Medicine

Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?

Olga A Martin, Robin L Anderson, Kailash Narayan, Michael P MacManus

Journal article  |  2017  |  Nature Reviews Clinical Oncology

Compromized DNA repair as a basis for identification of cancer radiotherapy patients with extreme radiosensitivity

Pavel Lobachevsky, Trevor Leong, Patricia Daly, Jai Smith, Nickala Best, Jonathan Tomaszewski, Ella R Thompson, Na Li, Ian G Campbell, Roger F Martin, Olga A Martin

Journal article  |  2016  |  Cancer Letters

Empowering patients for radiation therapy safety: Results of the EMPATHY study.

J-E Bibault, A Pernet, V Mollo, L Gourdon, O Martin, P Giraud

Journal article  |  2016  |  Cancer/Radiothérapie

PURPOSE: With the increase of treatment complexity, enhancing safety is a key concern in radiation oncology. Beyond the involvemen..

Radiotherapy for Non-Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues

Shankar Siva, Pavel Lobachevsky, Michael P MacManus, Tomas Kron, Andreas Moller, Richard J Lobb, Jessica Ventura, Nickala Best, Jai Smith, David Ball, Olga A Martin

Journal article  |  2016  |  Clinical Cancer Research

Evaluation of surrogate tissues as indicators of drug activity in a melanoma skin model

Palak R Parekh, Rohini Choudhuri, Urbain Weyemi, Olga A Martin, William M Bonner, Christophe E Redon

Journal article  |  2016  |  Cancer Medicine

Potential strategies to ameliorate risk of radiotherapy-induced second malignant neoplasms

Olga A Martin, Xiaoyu Yin, Helen B Forrester, Carl N Sprung, Roger F Martin

Journal article  |  2016  |  Seminars in Cancer Biology

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)

Zacharenia Nikitaki, Vladimir Nikolov, Ifigeneia V Mavragani, Emil Mladenov, Anastasios Mangelis, Danae A Laskaratou, Georgios I Fragkoulis, Christine E Hellweg, Olga A Martin, Dimitris Emfietzoglou, Vasiliki I Hatzi, Georgia I Terzoudi, George Iliakis, Alexandros G Georgakilas

Journal article  |  2016  |  Free Radical Research

Assessment and Implications of Scattered Microbeam and Broadbeam Synchrotron Radiation for Bystander Effect Studies

Pavel Lobachevsky, Alesia Ivashkevich, Helen B Forrester, Andrew W Stevenson, Chris J Hall, Carl N Sprung, Olga A Martin

Journal article  |  2015  |  Radiation Research

Immunological markers that predict radiation toxicity

Carl N Sprung, Helen B Forrester, Shankar Siva, Olga A Martin

Journal article  |  2015  |  Cancer Letters

Building immunity to cancer with radiation therapy

Suresh J Haikerwal, Jim Hagekyriakou, Michael MacManus, Olga A Martin, Nicole M Haynes

Journal article  |  2015  |  Cancer Letters

Evaluation of Severe Combined Immunodeficiency and Combined Immunodeficiency Pediatric Patients on the Basis of Cellular Radiosensitivity

Pavel Lobachevsky, Lisa Woodbine, Kuang-Chih Hsiao, Sharon Choo, Chris Fraser, Paul Gray, Jai Smith, Nickala Best, Laura Munforte, Elena Korneeva, Roger F Martin, Penny A Jeggo, Olga A Martin

Journal article  |  2015  |  The Journal of Molecular Diagnostics

Analysis of Lu-177-DOTA-Octreotate Therapy-Induced DNA Damage in Peripheral Blood Lymphocytes of Patients with Neuroendocrine Tumors

Delphine Denoyer, Pavel Lobachevsky, Price Jackson, Mick Thompson, Olga A Martin, Rodney J Hicks

Journal article  |  2015  |  Journal of Nuclear Medicine

Abscopal effects of radiation therapy: A clinical review for the radiobiologist

Shankar Siva, Michael P MacManus, Roger F Martin, Olga A Martin

Journal article  |  2015  |  Cancer Letters

Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects

Carl N Sprung, Alesia Ivashkevich, Helen B Forrester, Christophe E Redon, Alexandros Georgakilas, Olga A Martin

Journal article  |  2015  |  Cancer Letters

Age-Dependent Changes in DNA Repair in Radiation-Exposed Mice

Igor P Kovalchuk, Andrey Golubov, Igor V Koturbash, Kristy Kutanzi, Olga A Martin, Olga Kovalchuk

Journal article  |  2014  |  Radiation Research

Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant Tempol

Alexandros G Georgakilas, Christophe E Redon, Nicholas F Ferguson, Thomas B Kryston, Palak Parekh, Jennifer S Dickey, Asako J Nakamura, James B Mitchell, William M Bonner, Olga A Martin

Journal article  |  2014  |  Cancer Letters

A Pattern of Early Radiation-Induced Inflammatory Cytokine Expression Is Associated with Lung Toxicity in Patients with Non-Small Cell Lung Cancer

Shankar Siva, Michael MacManus, Tomas Kron, Nickala Best, Jai Smith, Pavel Lobachevsky, David Ball, Olga Martin

Journal article  |  2014  |  PLOS ONE

A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer

Shankar Siva, Jason Callahan, Tomas Kron, Olga A Martin, Michael P MacManus, David L Ball, Rodney J Hicks, Michael S Hofman

Journal article  |  2014  |  BMC CANCER

Mobilization of Viable Tumor Cells Into the Circulation During Radiation Therapy

Olga A Martin, Robin L Anderson, Prudence A Russell, R Ashley Cox, Alesia Ivashkevich, Agnieszka Swierczak, Judy P Doherty, Daphne HM Jacobs, Jai Smith, Shankar Siva, Patricia E Daly, David L Ball, Roger F Martin, Michael P MacManus

Journal article  |  2014  |  International Journal of Radiation Oncology*Biology*Physics

Inflammation and Oxidative DNA Damage: A Dangerous Synergistic Pathway to Cancer

OA Martin, S Nowsheen, S Siva, K Aziz, VI Hatzi, AG Georgakilas

Book Chapter  |  2014

Statistical analysis of kinetics, distribution and co-localisation of DNA repair foci in irradiated cells: Cell cycle effect and implications for prediction of radiosensitivity

Olga A Martin, Alesia Ivashkevich, Sharon Choo, Lisa Woodbine, Penny A Jeggo, Roger F Martin, Pavel Lobachevsky

Journal article  |  2013  |  DNA Repair

Asbcopal Effects after Conventional and Stereotactic Lung Irradiation of Non-Small-Cell Lung Cancer

Shankar Siva, Jason Callahan, Michael P MacManus, Olga Martin, Rodney J Hicks, David L Ball

Journal article  |  2013  |  Journal of Thoracic Oncology

Use of the gamma-H2AX assay to monitor DNA damage and repair in cancer research

Alesia Ivashkevich, Christophe E Redon, Asako J Nakamura, Roger F Martin, Olga A Martin

Journal article  |  2012  |  Cancer Letters

Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity

Jennifer S Dickey, Brandon J Baird, Christophe E Redon, Valeriya Avdoshina, Guillermo Palchik, Junfang Wu, Alexei Kondratyev, William M Bonner, Olga A Martin

Journal article  |  2012  |  Nucleic Acids Research

Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma

Gerard Adams, Olga A Martin, Daniel E Roos, Pavel N Lobachevsky, Andrew E Potter, Andrew C Zacest, Eva Bezak, William M Bonner, Roger F Martin, Trevor Leong

Journal article  |  2012  |  Radiotherapy and Oncology

The role of miRNA in the direct and indirect effects of ionizing radiation

Jennifer S Dickey, Franz J Zemp, Olga A Martin, Olga Kovalchuk

Journal article  |  2011  |  Radiation and Environmental Biophysics

gamma H2AX foci as a measure of DNA damage: A computational approach to automatic analysis

Alesia N Ivashkevich, Olga A Martin, Andrea J Smith, Christophe E Redon, William M Bonner, Roger F Martin, Pavel N Lobachevsky

Journal article  |  2011  |  Mutation Research

Hypothermia postpones DNA damage repair in irradiated cells and protects against cell killing

Brandon J Baird, Jennifer S Dickey, Asako J Nakamura, Christophe E Redon, Palak Parekh, Yuri V Griko, Khaled Aziz, Alexandros G Georgakilas, William M Bonner, Olga A Martin

Journal article  |  2011  |  Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals

Darryl Hudson, Igor Kovalchuk, Igor Koturbash, Bryan Kolb, Olga A Martin, Olga Kovalchuk

Journal article  |  2011  |  Aging

Systemic DNA Damage Related to Cancer

Olga A Martin, Christophe E Redon, Asako J Nakamura, Jennifer S Dickey, Alexandros G Georgakilas, William M Bonner

Journal article  |  2011  |  Cancer Research

Recent developments in the use of gamma-H2AX as a quantitative DNA double-strand break biomarker

Christophe E Redon, Asako J Nakamura, Olga A Martin, Palak R Parekh, Urbain S Weyemi, William M Bonner

Journal article  |  2011  |  Aging

H2AX in DNA Damage Response

Christophe E Redon, Jennifer S Dickey, Asako J Nakamura, Olga A Martin, William M Bonner

Book Chapter  |  2011  |  Current Cancer Research

Para-inflammation mediates systemic DNA damage in response to tumor growth.

Olga A Martin, Christophe E Redon, Jennifer S Dickey, Asako J Nakamura, William M Bonner

Journal article  |  2011  |  Communicative & integrative biology

The radiation induced bystander effect is a well-accepted consequence of ionizing radiation exposure. However, it has become clear..