Sofya Golenkina

Tumor-derived MMPs regulate cachexia in a Drosophila cancer model

William Lodge, Michael Zavortink, Sofia Golenkina, Francesca Froldi, Callum Dark, Shane Cheung, Benjamin L Parker, Ronnie Blazev, Daniel Bakopoulos, Elizabeth L Christie, Verena C Wimmer, Brigette C Duckworth, Helena E Richardson, Louise Y Cheng

Journal article  |  2021  |  DEVELOPMENTAL CELL

Cachexia, the wasting syndrome commonly observed in advanced cancer patients, accounts for up to one-third of cancer-related morta..

Glial Hedgehog signalling and lipid metabolism regulate neural stem cell proliferation in Drosophila

Qian Dong, Michael Zavortink, Francesca Froldi, Sofya Golenkina, Tammy Lam, Louise Y Cheng

Journal article  |  2021  |  EMBO REPORTS

The final size and function of the adult central nervous system (CNS) are determined by neuronal lineages generated by neural stem..

Exploiting Drosophila melanogaster Wing Imaginal Disc Eversion to Screen for New EMT Effectors

Sofia Golenkina, Rosemary Manhire-Heath, Michael J Murray

Journal article  |  2021  |  EPITHELIAL-TO MESENCHYMAL TRANSITION

In the early stages of Drosophila melanogaster (Drosophila) metamorphosis, a partial epithelial-mesenchymal transition (pEMT) take..

Frazzled can act through distinct molecular pathways in epithelial cells to regulate motility, apical constriction, and localisation of E-Cadherin

Sofia Golenkina, Vishal Chaturvedi, Robert Saint, Michael J Murray

Journal article  |  2018  |  PLOS ONE

Netrin receptors of the DCC/NEO/UNC-40/Frazzled family have well established roles in cell migration and axon guidance but can als..