profile icon
Dr

Sophie Payne

Honorary
Medical Bionics Department
animals
rats
female
science & technology
optic nerve injuries
life sciences & biomedicine
neurosciences & neurology
neurosciences
oxidative stress
Sophie Payne's Profile Picture
Dr

Sophie Payne

 
Division
Medicine, Dentistry And Health Sciences
Sophie Payne's Profile Picture
Dr

Sophie Payne

 
Print
Sophie's  Short Profile
 

Prior to joining the Bionics Institute, Sophie completed her PhD at the University of Western Australia (2009-2013), where she investigated long term effects of injury in the visual system. In 2012, Sophie started her first post doctorate position with Professor Janet Keast at the University of Melbourne (2013-2015) and assessed regeneration and repair of the peripheral nervous system.

Sophie started working at the Bionics Institute in 2015 on a project investigating neuromodulation of the vagus nerve for the treatment of inflammatory bowel disease. She works with a high profile team of neuroscientists, engineers, mathematical modellers and clinicians to generate proof-of-concept data required before this technology goes to clinical trials. Recently, Sophie’s interests have expanded to include whether peripheral nerve stimulation can be applied to treat other conditions of visceral organs. Sophie has imparted her knowledge and passion for her research through mentorship programs for recent graduates, and presentations to non-scientific community groups. To get a better understanding of the diseases she works on, Sophie is a member of Crohn’s and Colitis Australia and Diabetes Victoria. She is also on the Aikenhead Centre for Medical Discovery steering committee, which promotes excellence in clinical research, and facilitates an annual symposium.

Find out more about Sophie Payne's experience

Sophie Payne's highlights

Projects

Displaying the 1 most recent project by Sophie Payne.

Project icon

INVESTIGATING THE INTEGRITY OF MYELIN SHEATH AND NODE MORPHOLOGY IN THE OPTIC NERVE FOLLOWING BLINDNESS

2016 - 2017
Completed

1

Projects

Project Types

1

Internal Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works by Sophie Payne.

Scholarly works icon

Anti-inflammatory Effects of Abdominal Vagus Nerve Stimulation on Experimental Intestinal Inflammation

Sophie C Payne, John B Furness, Owen Burns, Alicia Sedo, Tomoko Flyakumurat, Robert K Shepherd, James B Fallon

Journal article  |  2019  |  Frontiers in Neuroscience

Scholarly works icon

Bioelectric neuromodulation for gastrointestinal disorders: effectiveness and mechanisms

Sophie C Payne, John B Furness, Martin J Stebbing

Journal article  |  2019  |  Nature Reviews Gastroenterology & Hepatology

Scholarly works icon

An objective in vivo diagnostic method for inflammatory bowel disease

Sophie C Payne, Robert K Shepherd, Alicia Sedo, James B Fallon, John B Furness

Journal article  |  2018  |  Royal Society Open Science

Scholarly works icon

Peripheral injury of pelvic visceral sensory nerves alters GFR alpha (GDNF family receptor alpha) localization in sensory and autonomic pathways of the sacral spinal cord

Shelley L Forrest, Sophie C Payne, Janet P Keast, Peregrine B Osborne

Journal article  |  2015  |  FRONTIERS IN NEUROANATOMY

Scholarly works icon

Regeneration of sensory but not motor axons following visceral nerve injury

Sophie C Payne, Philip J Belleville, Janet R Keast

Journal article  |  2015  |  EXPERIMENTAL NEUROLOGY

Scholarly works icon

Neurite outgrowth in normal and injured primary sensory neurons reveals different regulation by nerve growth factor (NGF) and artemin

Agnes W Wong, James KP Yeung, Sophie C Payne, Janet R Keast, Peregrine B Osborne

Journal article  |  2015  |  Molecular and Cellular Neuroscience

Scholarly works icon

Paranode Abnormalities and Oxidative Stress in Optic Nerve Vulnerable to Secondary Degeneration: Modulation by 670 nm Light Treatment.

Charis R Szymanski, Wissam Chiha, Natalie Morellini, Nadia Cummins, Carole A Bartlett, Ryan L O'Hare Doig, Donna L Savigni, Sophie C Payne, Alan R Harvey, Sarah A Dunlop, Melinda Fitzgerald

Journal article  |  2013  |  PLoS One

Secondary degeneration of nerve tissue adjacent to a traumatic injury results in further loss of neurons, glia and function, via m..

Scholarly works icon

Early proliferation does not prevent the loss of oligodendrocyte progenitor cells during the chronic phase of secondary degeneration in a CNS white matter tract.

Sophie C Payne, Carole A Bartlett, Donna L Savigni, Alan R Harvey, Sarah A Dunlop, Melinda Fitzgerald

Journal article  |  2013  |  PLoS ONE

Partial injury to the central nervous system (CNS) is exacerbated by additional loss of neurons and glia via toxic events known as..

Scholarly works icon

Myelin sheath decompaction, axon swelling, and functional loss during chronic secondary degeneration in rat optic nerve.

Sophie C Payne, Carole A Bartlett, Alan R Harvey, Sarah A Dunlop, Melinda Fitzgerald

Journal article  |  2012  |  Invest Ophthalmol Vis Sci

PURPOSE: To examine chronic changes occurring at 6 months following partial optic nerve (ON) transection, assessing optic axons, m..

Scholarly works icon

Chronic swelling and abnormal myelination during secondary degeneration after partial injury to a central nervous system tract.

Sophie C Payne, Carole A Bartlett, Alan R Harvey, Sarah A Dunlop, Melinda Fitzgerald

Journal article  |  2011  |  Journal of Neurotrauma

Secondary degeneration is a serious consequence of traumatic injury to the central nervous system (CNS) and involves the progressi..

12

Scholarly Works

Keyword Analysis

Neurosciences
Clinical Health (organs, Diseases and Abnormal Conditions)
Clinical Sciences
Biomedical Engineering

Honours, Awards and Fellowships

2019

Best Senior Investigator Oral presentation

ACMD
2018

Best Moderate Oral presentation

ACMD
2017

Best Moderate Oral presentation

ACMD
2016

CSL Stipend for UROP Student

CSL
2016

Harold Mitchell Travel Scholarship

Harold Mitchell Foundation
2012

Australian Postgraduate Award

6

Awards

Credentials

Positions

Positions

Honorary

Medical Bionics Department

Education

Education

Doctor of Philosophy (Neuroscience)

University of Western Australia

Bachelor of Science (Honours)

The University of Western Australia