Sarah Dunstan

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

Gavin Band, Quang Si Le, Geraldine M Clarke, Katja Kivinen, Christina Hubbart, Anna E Jeffreys, Kate Rowlands, Ellen M Leffler, Muminatou Jallow, David J Conway, Fatoumatta Sisay-Joof, Giorgio Sirugo, Umberto d'Alessandro, Ousmane B Toure, Mahamadou A Thera, Salimata Konate, Sibiri Sissoko, Valentina D Mangano, Edith C Bougouma, Sodiomon B Sirima, et al.

Journal article  |  2019  |  Nature Communications

Understanding the global tuberculosis epidemic: moving towards routine whole-genome sequencing.

SJ Dunstan, DA Williamson, JT Denholm

Journal article  |  2019  |  The International Journal of Tuberculosis and Lung Disease

Empirical ways to identify novel Bedaquiline resistance mutations in AtpE

Malancha Karmakar, Carlos HM Rodrigues, Kathryn E Holt, Sarah J Dunstan, Justin Denholm, David B Ascher

Journal article  |  2019  |  PLOS ONE

Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

Ola B Brynildsrud, Caitlin S Pepperell, Philip Suffys, Louis Grandjean, Johana Monteserin, Nadia Debech, Jon Bohlin, Kristian Alfsnes, John O-H Pettersson, Ingerid Kirkeleite, Fatima Fandinho, Marcia Aparecida da Silva, Joao Perdigao, Isabel Portugal, Miguel Viveiros, Taane Clark, Maxine Caws, Sarah Dunstan, Vuong Khac Thai Phan, Beatriz Lopez, et al.

Journal article  |  2018  |  Science Advances

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

Carolyne M Ndila, Sophie Uyoga, Alexander W Macharia, Gideon Nyutu, Norbert Peshu, John Ojal, Mohammed Shebe, Kennedy O Awuondo, Neema Mturi, Benjamin Tsofa, Nuno Sepulveda, Taane G Clark, Gavin Band, Geraldine Clarke, Kate Rowlands, Christina Hubbart, Anna Jeffreys, Silvia Kariuki, Kevin Marsh, Margaret Mackinnon, et al.

Journal article  |  2018  |  The Lancet Haematology

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

Kathryn E Holt, Paul McAdam, Vuong Khac Thai Phan, Thuy Thuong Thuong Nguyen, Thi Minh Ha Dang, Ngoc Lan Nguyen, Huu Lan Nguyen, Thi Quynh Nhu Nguyen, Thanh Hai Hoang, Thi Ngoc Ha Vu, Guy Thwaites, David J Edwards, Artika P Nath, Kym Pham, David B Ascher, Jeremy Farrar, Chiea Chuen Khor, Yik Ying Teo, Michael Inouye, Maxine Caws, et al.

Journal article  |  2018  |  Nature Genetics

Could omics unlock the secret of surviving tuberculous meningitis?

Sarah J Dunstan, Maxine Caws

Journal article  |  2018  |  The Lancet Infectious Diseases

Bacterial risk factors for treatment failure and relapse among patients with isoniazid resistant tuberculosis

Vuong Khac Thai Phan, Thi Minh Ha Dang, Thi Hanh Nguyen, Jeremy Day, Sarah Dunstan, Thi Quynh Nhu Nguyen, Sy Kiet Vo, Huu Lan Nguyen, Huy Dung Nguyen, Thi Ngoc Lan Nguyen, Thuong Thuong Nguyen, Ngoc Lan Nguyen, Thi Thuy Lieu Pham, Thi Hong Nguyen, Cong Diep Dao, Thi Kim Thanh Nguyen, Van Hoi Nguyen, Van Nghia Nguyen, Ngoc Dai Truong, Quang Minh Hoang, et al.

Journal article  |  2018  |  BMC Infectious Diseases

Tuberculous meningitis

Robert J Wilkinson, Ursula Rohlwink, Usha Kant Misra, Reinout van Crevel, Thi Hoang Mai Nguyen, Kelly E Dooley, Maxine Caws, Anthony Figaji, Rada Savic, Regan Solomons, Guy E Thwaites

Journal article  |  2017  |  Nature Reviews Neurology

Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol

Monica I Alvarez, Luke C Glover, Peter Luo, Liuyang Wang, Elizabeth Theusch, Stefan H Oehlers, Eric M Walton, Thi Bich Tram Trinh, Yu-Lin Kuang, Jerome I Rotter, Colleen M McClean, Tran Chinh Nguyen, Marisa W Medina, David M Tobin, Sarah J Dunstan, Dennis C Ko

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys

Thomas C Darton, James E Meiring, Susan Tonks, Md Arifuzzaman Khan, Farhana Khanam, Mila Shakya, Deus Thindwa, Stephen Baker, Buddha Basnyat, John D Clemens, Gordon Dougan, Christiane Dolecek, Sarah J Dunstan, Melita A Gordon, Robert S Heyderman, Kathryn E Holt, Virginia E Pitzer, Firdausi Qadri, K Zaman, Andrew J Pollard

Journal article  |  2017  |  BMJ Open

The SIGLEC14 null allele is associated with Mycobacterium tuberculosis and BCG-induced clinical and immunologic outcomes

Andrew D Graustein, David J Horne, Jerry J Fong, Flavio Schwarz, Heather C Mefford, Glenna J Peterson, Richard D Wells, Munyaradzi Musvosvi, Muki Shey, Willem A Hanekom, Mark Hatherill, Thomas J Scriba, Thuy Thuong Thuong Nguyen, Thi Hoang Mai Nguyen, Maxine Caws, Duc Bang Nguyen, Sarah J Dunstan, Guy E Thwaites, Ajit Varki, Takashi Angata, et al.

Journal article  |  2017  |  Tuberculosis

Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis

Nguyen TT Thuong, Dorothee Heemskerk, Trinh TB Tram, Le TP Thao, Lalita Ramakrishnan, Vu TN Ha, Nguyen D Bang, Tran TH Chau, Nguyen H Lan, Maxine Caws, Sarah J Dunstan, Nguyen VV Chau, Marcel Wolbers, Nguyen TH Mai, Guy E Thwaites

Journal article  |  2017  |  The Journal of Infectious Diseases

Characterising private and shared signatures of positive selection in 37 Asian populations

Xuanyao Liu, Dongsheng Lu, Woei-Yuh Saw, Philip J Shaw, Pongsakorn Wangkumhang, Chumpol Ngamphiw, Suthat Fucharoen, Worachart Lert-itthiporn, Kwanrutai Chin-inmanu, Nguyen Bich Chau Tran, Katie Anders, Anuradhani Kasturiratne, H Janaka de Silva, Tomohiro Katsuya, Ryosuke Kimura, Toru Nabika, Takayoshi Ohkubo, Yasuharu Tabara, Fumihiko Takeuchi, Ken Yamamoto, et al.

Journal article  |  2017  |  European Journal of Human Genetics

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

Geraldine M Clarke, Kirk Rockett, Katja Kivinen, Christina Hubbart, Anna E Jeffreys, Kate Rowlands, Muminatou Jallow, David J Conway, Kalifa A Bojang, Margaret Pinder, Stanley Usen, Fatoumatta Sisay-Joof, Giorgio Sirugo, Ousmane Toure, Mahamadou A Thera, Salimata Konate, Sibiry Sissoko, Amadou Niangaly, Belco Poudiougou, Valentina D Mangano, et al.

Journal article  |  2017  |  eLife

A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis

C Seshadri, NTT Thuong, NTH Mai, ND Bang, TTH Chau, DM Lewinsohn, GE Thwaites, SJ Dunstan, TR Hawn

Journal article  |  2017  |  Genes & Immunity

MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage

NTT Thuong, TTB Tram, TD Dinh, PVK Thai, D Heemskerk, ND Bang, TTH Chau, DG Russell, GE Thwaites, TR Hawn, M Caws, SJ Dunstan

Journal article  |  2016  |  Genes & Immunity

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

Chiea Chuen Khor, Tan Do, Hongyan Jia, Masakazu Nakano, Ronnie George, Khaled Abu-Amero, Roopam Duvesh, Li Jia Chen, Zheng Li, Monisha E Nongpiur, Shamira A Perera, Chunyan Qiao, Hon-Tym Wong, Hiroshi Sakai, Monica Barbosa de Melo, Mei-Chin Lee, Anita S Chan, Yaakub Azhany, Thi Lam Huong Dao, Yoko Ikeda, et al.

Journal article  |  2016  |  Nature Genetics

GeneXpert MTB/Rif to Diagnose Tuberculous Meningitis: Perhaps the First Test but not the Last

Nathan C Bahr, Suzaan Marais, Maxine Caws, Reinout van Crevel, Robert J Wilkinson, Jaya S Tyagi, Guy E Thwaites, David R Boulware

Journal article  |  2016  |  Clinical Infectious Diseases

High prevalence of PI resistance in patients failing second-line ART in Vietnam

Phuong Thao Vu, Minh Quang Vo, Jeremy N Day, Tran Chinh Nguyen, Cecilia M Shikuma, Jeremy Farrar, Van Vinh Chau Nguyen, Guy E Thwaites, Sarah J Dunstan, Le Thuy

Journal article  |  2016  |  Journal of Antimicrobial Chemotherapy

Second-Line HIV Therapy Outcomes and Determinants of Mortality at the Largest HIV Referral Center in Southern Vietnam

Phuong Thao Vu, Vo Minh Quang, Marcel Wolbers, Duc Anh Nguyen, Cecilia Shikuma, Jeremy Farrar, Sarah Dunstan, Van Vinh Chau Nguyen, Jeremy Day, Guy Thwaites, Le Thuy

Journal article  |  2015  |  Medicine

A global reference for human genetic variation

David M Altshuler, Richard M Durbin, Goncalo R Abecasis, David R Bentley, Aravinda Chakravarti, Andrew G Clark, Peter Donnelly, Evan E Eichler, Paul Flicek, Stacey B Gabriel, Richard A Gibbs, Eric D Green, Matthew E Hurles, Bartha M Knoppers, Jan O Korbel, Eric S Lander, Charles Lee, Hans Lehrach, Elaine R Mardis, Gabor T Marth, et al.

Journal article  |  2015  |  Nature

LTA4H Genotype Is Associated with Susceptibility to Bacterial Meningitis but Is Not a Critical Determinant of Outcome

Sarah J Dunstan, Thi Bich Tram Trinh, Guy E Thwaites, Thi Hong Chau Tran, Hoan Phu Nguyen, Tinh Hien Tran, Jeremy J Farrar, Marcel Wolbers, Thi Hoang Mai Nguyen

Journal article  |  2015  |  PLOS ONE

TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam

AD Graustein, DJ Horne, M Arentz, ND Bang, TTH Chau, GE Thwaites, M Caws, NTT Thuong, SJ Dunstan, TR Hawn

Journal article  |  2015  |  Tuberculosis

Common Polymorphisms in the CD43 Gene Region Are Associated with Tuberculosis Disease and Mortality

Monica Campo, April K Randhawa, Sarah Dunstan, Jeremy Farrar, Maxine Caws, Duc Bang Nguyen, Ngoc Lan Nguyen, Thi Hong Chau Tran, David J Horne, Thuong Thuong Nguyen, Guy E Thwaites, Thomas R Hawn

Journal article  |  2015  |  American Journal of Respiratory Cell and Molecular Biology

Variation at HLA-DRB1 is associated with resistance to enteric fever

Sarah J Dunstan, Thi Hue Nguyen, Han Buhm, Zheng Li, Thi Bich Tram Trinh, Kar Seng Sim, Christopher M Parry, Tran Chinh Nguyen, Vinh Ha, Phu Huong Lan Nguyen, Tran Vu Thieu Nga, Voong Vinh Phat, Samir Koirala, Sabina Dongol, Amit Arjyal, Abhilasha Karkey, Olita Shilpakar, Christiane Dolecek, Jia Nee Foo, Thi Phuong Le, et al.

Journal article  |  2014  |  Nature Genetics

Reappraisal of known malaria resistance loci in a large multicenter study

Kirk A Rockett, Geraldine M Clarke, Kathryn Fitzpatrick, Christina Hubbart, Anna E Jeffreys, Kate Rowlands, Rachel Craik, Muminatou Jallow, David J Conway, Kalifa A Bojang, Margaret Pinder, Stanley Usen, Fatoumatta Sisay-Joof, Giorgio Sirugo, Ousmane Toure, Mahamadou A Thera, Salimata Konate, Sibiry Sissoko, Amadou Niangaly, Belco Poudiougou, et al.

Journal article  |  2014  |  Nature Genetics

A polymorphism in human CD1A is associated with susceptibility to tuberculosis

C Seshadri, NTT Thuong, NTB Yen, ND Bang, TTH Chau, GE Thwaites, SJ Dunstan, TR Hawn

Journal article  |  2014  |  Genes & Immunity

A Polymorphism In The Tlr9 Gene Region Is Associated With Susceptibility To Tuberculosis In Vietnam

A Graustein, DJ Horne, M Arentz, ND Bang, TTH Chau, G Thwaites, NTT Thuong, S Dunstan, TJ Hawn

Conference Proceedings  |  2014  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Common Polymorphisms In The Cd43 Gene Region Are Associated With Tuberculosis Susceptibility And Mortality

M Campo, AK Randhawa, S Dunstan, J Farrar, M Caws, N Duc Bang, N Ngoc Lan, TT Hong Chau, DJ Horne, NT Thuong, G Thwaites, TR Hawn

Conference Proceedings  |  2014  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

James C Lee, Marion Espeli, Carl A Anderson, Michelle A Linterman, Joanna M Pocock, Naomi J Williams, Rebecca Roberts, Sebastien Viatte, Bo Fu, Norbert Peshu, Tinh Hien Tran, Hoan Phu Nguyen, Emma Wesley, Cathryn Edwards, Tariq Ahmad, John C Mansfield, Richard Gearry, Sarah Dunstan, Thomas N Williams, Anne Barton, et al.

Journal article  |  2013  |  CELL

An updated systematic review of the role of host genetics in susceptibility to influenza

Peter Horby, Nhu Y Nguyen, Sarah J Dunstan, John Kenneth Baillie

Journal article  |  2013  |  Influenza and Other Respiratory Viruses

TM4SF20 Ancestral Deletion and Susceptibility to a Pediatric Disorder of Early Language Delay and Cerebral White Matter Hyperintensities

Wojciech Wiszniewski, Jill V Hunter, Neil A Hanchard, Jason R Willer, Chad Shaw, Qi Tian, Anna Illner, Xueqing Wang, Sau W Cheung, Ankita Patel, Ian M Campbell, Violet Gelowani, Patricia Hixson, Audrey R Ester, Mahshid S Azamian, Lorraine Potocki, Gladys Zapata, Patricia P Hernandez, Melissa B Ramocki, Regie LP Santos-Cortez, et al.

Journal article  |  2013  |  American Journal of Human Genetics

Ancestral Deletion and Susceptibility to a Pediatric Disorder of Early Language Delay and Cerebral White Matter Hyperintensities.

Wojciech Wiszniewski, Jill V Hunter, Neil A Hanchard, Jason R Willer, Chad Shaw, Qi Tian, Anna Illner, Xueqing Wang, Sau W Cheung, Ankita Patel, Ian M Campbell, Violet Gelowani, Patricia Hixson, Audrey R Ester, Mahshid S Azamian, Lorraine Potocki, Gladys Zapata, Patricia P Hernandez, Melissa B Ramocki, Regie LP Santos-Cortez, et al.

Journal article  |  2013  |  The American Journal of Human Genetics

Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid

Li Liang, Silvia Juarez, Vu Thieu Nga Tran, Sarah Dunstan, Rie Nakajima-Sasaki, D Huw Davies, Stephen McSorley, Stephen Baker, Philip L Felgner

Journal article  |  2013  |  Scientific Reports

Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese

SJ Dunstan, KA Rocketts, NTN Quyen, YY Teo, CQ Thai, NT Hang, A Jeffreys, TG Clark, KS Small, CP Simmons, N Day, SE O'Riordan, DP Kwiatkowski, J Farrar, NH Phu, TT Hien

Journal article  |  2012  |  Genes and Immunity

Human TOLLIP Regulates TLR2 and TLR4 Signaling and Its Polymorphisms Are Associated with Susceptibility to Tuberculosis

Javeed A Shah, Jay C Vary, Tran TH Chau, Nguyen D Bang, Nguyen TB Yen, Jeremy J Farrar, Sarah J Dunstan, Thomas R Hawn

Journal article  |  2012  |  Journal of Immunology

Epiregulin (EREG) variation is associated with susceptibility to tuberculosis

NTT Thuong, TR Hawn, TTH Chau, ND Bang, NTB Yen, GE Thwaites, YY Teo, M Seielstad, M Hibberd, NTN Lan, M Caws, JJ Farrar, SJ Dunstan

Journal article  |  2012  |  Genes and Immunity

The Role of Host Genetics in Susceptibility to Influenza: A Systematic Review

Peter Horby, Nhu Y Nguyen, Sarah J Dunstan, J Kenneth Baillie

Journal article  |  2012  |  PLoS One

Common Polymorphisms in the PKP3-SIGIRR-TMEM16J Gene Region Are Associated With Susceptibility to Tuberculosis

David J Horne, April K Randhawa, Tran TH Chau, Nguyen D Bang, Nguyen TB Yen, Jeremy J Farrar, Sarah J Dunstan, Thomas R Hawn

Journal article  |  2012  |  Journal of Infectious Diseases

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

David M Tobin, Francisco J Roca, Sungwhan F Oh, Ross McFarland, Thad W Vickery, John P Ray, Dennis C Ko, Yuxia Zou, Nguyen D Bang, Tran TH Chau, Jay C Vary, Thomas R Hawn, Sarah J Dunstan, Jeremy J Farrar, Guy E Thwaites, Mary-Claire King, Charles N Serhan, Lalita Ramakrishnan

Journal article  |  2012  |  Cell

HIV-1 drug resistance in antiretroviral-naive individuals with HIV-1-associated tuberculous meningitis initiating antiretroviral therapy in Vietnam

Vu P Thao, Le Thuy, Estee M Toeroek, Nguyen TB Yen, Tran TH Chau, Suzanne Jurriaans, Rogier H van Doorn, Menno D de Jong, Jeremy J Farrar, Sarah J Dunstan

Journal article  |  2012  |  Antiviral Therapy

Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1

Chiea Chuen Khor, Nguyen Bich Chau Tran, Junxiong Pang, Sonia Davila, Truong Long Hoang, Rick TH Ong, Sarah J Dunstan, Bridget Wills, Jeremy Farrar, Van Tram Ta, Thi Gan Tran, Thi Nguyet Binh Nguyen, Trung Tri Le, Bich Lien Le, Minh Tuan Nguyen, Thi Hong Tham Nguyen, Ngoc Lanh Mai, Minh Nguyet Nguyen, Trong Hieu Nguyen, VanVinh Chau Nguyen, et al.

Journal article  |  2011  |  Nature Genetics

The variant call format and VCFtools

Petr Danecek, Adam Auton, Goncalo Abecasis, Cornelis A Albers, Eric Banks, Mark A DePristo, Robert E Handsaker, Gerton Lunter, Gabor T Marth, Stephen T Sherry, Gilean McVean, Richard Durbin

Journal article  |  2011  |  Bioinformatics

Human genetic susceptibility to tuberculous meningitis in Vietnamese population

NTT Thuong, S Dunstan

Journal article  |  2010  |  Kekkaku

What is the evidence of a role for host genetics in susceptibility to influenza A/H5N1?

P Horby, H Sudoyo, V Viprakasit, A Fox, PQ Thai, H Yu, S Davila, M Hibberd, SJ Dunstan, Y Monteerarat, JJ Farrar, S Marzuki, NT Hien

Journal article  |  2010  |  Epidemiology and Infection

Copy number, linkage disequilibrium and disease association in the FCGR locus

Heather A Niederer, Lisa C Willcocks, Tim F Rayner, Wanling Yang, Yu Lung Lau, Thomas N Williams, J Anthony G Scott, Britta C Urban, Norbert Peshu, Sarah J Dunstan, Tran Tinh Hien, Nguyen Hoan Phu, Leonid Padyukov, Iva Gunnarsson, Elisabet Svenungsson, Caroline O Savage, Richard A Watts, Paul A Lyons, David G Clayton, Kenneth GC Smith

Journal article  |  2010  |  Human Molecular Genetics

Large scale screening for haemoglobin disorders in southern Vietnam: implications for avoidance and management

Sean O'Riordan, Tinh Hien Tran, Katie Miles, Angela Allen, Ngoc Quyen Nguyen, Quoc Hung Nguyen, Quang Anh Do, Nguyen Tuyen Luc, Bach Khoa Dao, Quang Thai Cao, Minh Triet Dao, Hoan Phu Nguyen, Sarah Dunstan, Tim Peto, John Clegg, Jeremy Farrar, David Weatherall

Journal article  |  2010  |  British Journal of Haematology

The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens

Vu Thieu Nga Tran, Abhilasha Karkey, Sabina Dongol, Nguyen Thuy Hang, Sarah Dunstan, Kathryn Holt, Thi Phuong Tu Le, James I Campbell, Thuy Chau Tran, Van Vinh Chau Nguyen, Amit Arjyal, Samir Koirala, Buddha Basnyat, Christiane Dolecek, Jeremy Farrar, Stephen Baker

Journal article  |  2010  |  BMC Infectious Diseases

Leukotriene A4 Hydrolase (LTA4H) is expressed in leprosy lesions and variants are associated with susceptibility to mycobacterial diseases

JC Vary, DM Tobin, SJ Dunstan, ND Bang, DA Hagge, S Khadge, M King, L Ramakrishnan, TR Hawn

Conference Proceedings  |  2010  |  JOURNAL OF INVESTIGATIVE DERMATOLOGY

Abstracts

J Schulz, F Rosenow

Journal article  |  2010  |  eLife

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

David M Tobin, Jay C Vary, John P Ray, Gregory S Walsh, Sarah J Dunstan, Nguyen D Bang, Deanna A Hagge, Saraswoti Khadge, Mary-Claire King, Thomas R Hawn, Cecilia B Moens, Lalita Ramakrishnan

Journal article  |  2010  |  Cell

Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi

Lucinda J Thompson, Sarah J Dunstan, Christiane Dolecek, Tim Perkins, Deborah House, Gordon Dougan, Thi Hue Nguyen, Thi Phi La Tran, Doan Cong Du, Thi Phuong Le, Thi Dung Nguyen, Tinh Hien Tran, Jeremy J Farrar, Denise Monack, David J Lynn, Stephen J Popper, Stanley Falkow

Journal article  |  2009  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYTOKINE GENE SNPS ARE ASSOCIATED WITH SEVERE MALARIA IN VIETNAM

NTN Quyen, NH Phu, CQ Thai, TT Hien, JJ Farrar, SJ Dunstan

Conference Proceedings  |  2009  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Glucose-6-phosphate dehydrogenase (G6PD) mutations and haemoglobinuria syndrome in the Vietnamese population

Thi Hue Nguyen, Jean Paul Charlieu, Thi Hong Chau Tran, Nick Day, Jeremy J Farrar, Tinh Hien Tran, Sarah J Dunstan

Journal article  |  2009  |  Malaria Journal

Genome-wide and fine-resolution association analysis of malaria in West Africa

Muminatou Jallow, Yik Ying Teo, Kerrin S Small, Kirk A Rockett, Panos Deloukas, Taane G Clark, Katja Kivinen, Kalifa A Bojang, David J Conway, Margaret Pinder, Giorgio Sirugo, Fatou Sisay-Joof, Stanley Usen, Sarah Auburn, Suzannah J Bumpstead, Susana Campino, Alison Coffey, Andrew Dunham, Andrew E Fry, Angela Green, et al.

Journal article  |  2009  |  Nature Genetics

Toll-Like Receptor 4 (TLR4) and Typhoid Fever in Vietnam

Thi Hue Nguyen, Ngoc Lanh Mai, Thi Phuong Le, Vinh Ha, Tran Chinh Nguyen, Tinh Hien Tran, T Hieu Nguyen, Jeremy J Farrar, Sarah J Dunstan

Journal article  |  2009  |  PLoS One

A global network for investigating the genomic epidemiology of malaria

Dominic Kwiatkowski

Journal article  |  2008  |  Nature

Identification of Tuberculosis Susceptibility Genes with Human Macrophage Gene Expression Profiles

Thuy Thuong Thuong Nguyen, J Dunstan Sarah, Thi Hong Chau Tran, Thorsson Vesteinn, Cameron P Simmons, Than Ha Quyen Nguyen, E Thwaites Guy, Thi Ngoc Lan Nguyen, Hibberd Martin, Y Teo Yik, Seielstad Mark, Aderem Alan, J Farrar Jeremy, R Hawn Thomas

Journal article  |  2008  |  PLoS Pathogens

A Multi-Center Randomised Controlled Trial of Gatifloxacin versus Azithromycin for the Treatment of Uncomplicated Typhoid Fever in Children and Adults in Vietnam

Christiane Dolecek, Thi Phi La Tran, Ngoc Rang Nguyen, Thi Phuong Le, Vinh Ha, Quoc Tuan Phung, Cong Du Doan, Thi Be Bay Nguyen, Thanh Long Duong, Bich Ha Luong, Trung Binh Nguyen, Thi Anh Hong Nguyen, Ngoc Dung Pham, Ngoc Lanh Mai, Van Be Bay Phan, Anh Ho Vo, Van Minh Hoang Nguyen, Thu Thi Nga Tran, Thuy Chau Tran, Constance Schultsz, et al.

Journal article  |  2008  |  PLoS One

Whole genome-amplified DNA: insights and imputation

Yik Y Teo, Michael Inouye, Kerrin S Small, Andrew E Fry, Simon C Potter, Sarah J Dunstan, Mark Seielstad, Ines Barroso, Nicholas J Wareham, Kirk A Rockett, Dominic P Kwiatkowski, Panos Deloukas

Journal article  |  2008  |  Nature Methods

The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis

Maxine Caws, Guy Thwaites, Sarah Dunstan, Thomas R Hawn, Nguyen Thi Ngoc Lan, Nguyen Thuy Thuong Thuong, Kasia Stepniewska, Mai Nguyet Thu Huyen, Nguyen Duc Bang, Tran Huu Loc, Sebastien Gagneux, Dick van Soolingen, Kristin Kremer, Marianne van der Sande, Peter Small, Phan Thi Hoang Anh, Nguyen Tran Chinh, Hoang Thi Quy, Nguyen Thi Hong Duyen, Dau Quang Tho, et al.

Journal article  |  2008  |  PLoS Pathogens

Prevalence and molecular basis of alpha-thalassaemia in a malaria endemic region of Vietnam

NQ Nguyen, SP O'Riordan, QT Cao, MT Dao, TL Le, QA Do, K Miles, A Allen, TH Vu, HP Nguyen, SJ Dunstan, TE Peto, TH Tran, JJ Farrar, JB Clegg, DJ Weatherall, QH Nguyen

Conference Proceedings  |  2007  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A common human TLR1 polymorphism regulates the innate immune response to lipopeptides

Thomas R Hawn, E Ann Misch, Sarah J Dunstan, Guy E Thwaites, Nguyen TN Lans, Hoang T Quy, Tran TH Chau, Stephanie Rodrigues, Alex Nachman, Marta Janer, Tran T Hien, Jeremy J Farrar, Alan Aderem

Journal article  |  2007  |  European Journal of Immunology

A TNF region haplotype offers protection from typhoid fever in Vietnamese patients

Sarah J Dunstan, Nguyen Thi Hue, Kirk Rockett, Julian Forton, Andrew P Morris, P MorrisMahamadou Diakite, Mai Ngoc Lanh, Le Thi Phuong, Deborah House, Christopher M Parry, Ha Vinh, Nguyen T Hieu, Gordon Dougan, Tran Tinh Hien, Dominic Kwiatowski, Jeremy J Farrar

Journal article  |  2007  |  Human Genetics

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis

NTT Thuong, TR Hawn, GE Thwaites, TTH Chau, NTN Lan, HT Quy, NT Hieu, A Aderem, TT Hien, JJ Farrar, SJ Dunstan

Journal article  |  2007  |  Genes and Immunity

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis

Thomas R Hawn, Sarah J Dunstan, Guy E Thwaites, Cameron P Simmons, Nguyen Thuong Thuong, Thi Ngoc Lan Nguyen, Thi Quy Hoang, Thi Hong Chau Tran, Nguyen T Hieu, Stephanie Rodrigues, Marta Janer, Lue Ping Zhao, Tran Tinh Hien, Jeremy J Farrar, Alan Aderem

Journal article  |  2006  |  Journal of Infectious Diseases

Polymorphisms of the gene coding for copper/zinc superoxide dismutase (SOD1) in patients with Japanese encephalitis

NTT Thuong, SJ Dunstan, NM Dung, J-P Charlieu, HT Loan, B Wills, T Solomon, JJ Farrar

Journal article  |  2006  |  Pathogens and Global Health

Geographical distribution and disease associations of the CD45 exon 6 138G variant

V Ward, BJ Hennig, K Hirai, H Tahara, A Tamori, R Dawes, M Saito, C Bangham, H Stephens, AE Goldfeld, W Kunachiwa, N Leetrakool, J Hopkin, S Dunstan, A Hill, W Bodmer, PC Beverley, EZ Tchilian

Journal article  |  2006  |  Immunogenetics

Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam

SJ Dunstan, TR Hawn, NT Hue, CP Parry, VA Ho, H Vinh, TS Diep, D House, J Wain, A Aderem, TT Hien, JJ Farrar

Journal article  |  2005  |  Journal of Infectious Diseases

The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia

MJ Newport, A Allen, AA Awomoyi, SJ Dunstan, E McKinney, A Marchant, G Sirugo

Journal article  |  2004  |  Tuberculosis

In vitro and in vivo stability of recombinant plasmids in a vaccine strain of Salmonella enterica var. Typhimurium

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  2003  |  FEMS Immunology and Medical Microbiology

Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever

D House, NT Chinh, TT Hien, CP Parry, NT Ly, TS Diep, J Wain, S Dunstan, NJ White, G Dougan, JJ Farrar

Journal article  |  2002  |  Journal of Infectious Diseases

Typhoid fever and genetic polymorphisms at the natural resistance - Associated macrophage protein 1

SJ Dunstan, VA Ho, CM Duc, MN Lanh, CXT Phuong, C Luxemburger, J Wain, F Dudbridge, CS Peacock, D House, C Parry, TT Hien, G Dougan, J Farrar, JM Blackwell

Journal article  |  2001  |  Journal of Infectious Diseases

Salmonella: Immune responses and vaccines

P Mastroeni, JA Chabalgoity, SJ Dunstan, DJ Maskell, G Dougan

Journal article  |  2001  |  The Veterinary Journal

Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam

SJ Dunstan, HA Stephens, JM Blackwell, CM Duc, MN Lanh, F Dudbridge, CXT Phuong, C Luxemburger, J Wain, VA Ho, TT Hien, J Farrar, G Dougan

Journal article  |  2001  |  Journal of Infectious Diseases

The immune responses to bacterial antigens encountered in vivo at mucosal surfaces

G Dougan, M Ghaem-Maghami, D Pickard, G Frankel, G Douce, S Clare, S Dunstan, C Simmons

Journal article  |  2000  |  Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. typhimurium

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1999  |  Infection and Immunity

Bacterial vectors: why have they failed to deliver

R Strugnell, C Simmons, O Wijburg, T Uren, D Drew, S Dunstan

Journal article  |  1998  |  Australasian Biotechnology

Vaccine potential of attenuated mutants of Corynebacterium pseudotuberculosis in sheep

CP Simmons, SJ Dunstan, M Tachedjian, J Krywult, ALM Hodgson, RA Strugnell

Journal article  |  1998  |  Infection and Immunity

Comparison of the abilities of different attenuated Salmonella typhimurium strains to elicit humoral immune responses against a heterologous antigen

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1998  |  Infection and Immunity

Studies of the pathogenesis and immunology of attenuated mutants of Salmonella enterica var. Typhimurium: Lessons for human typhoid fever?

SJ Dunstan, CP Simmons, OLC Wijburg, TK Uren, N van Rooijen, RA Strugnell

Journal article  |  1998  |  Medical Journal of Indonesia

Development of recombinant S. Typhimurium, as a model for S. Typhi-based vaccine vectors

SJ Dunstan, CP Simmons, RA Strugnell

Journal article  |  1998  |  Medical Journal of Indonesia

DNA vaccines for bacterial infections

RA Strugnell, D Drew, J Mercieca, S DiNatale, N Firez, SJ Dunstan, CP Simmons, J Vadolas

Journal article  |  1997  |  Immunology and Cell Biology

The effect of attenuating mutations on the capacity of Salmonella enterica var. typhimurium to act as a vaccine vector

SJ Dunstan, CP Simmons, RA Strugnell

Conference Proceedings  |  1997  |  VACCINES 97 - MOLECULAR APPROACHES TO THE CONTROL OF INFECTIOUS DISEASES

Studies of immunity and bacterial invasiveness in mice given a recombinant Salmonella vector encoding murine interleukin-6

SJ Dunstan, AJ Ramsay, RA Strugnell

Journal article  |  1996  |  Infection and immunity

Cytokine gene knockout mice - Lessons for mucosal B-cell development

AJ Ramsay, SS Bao, KW Beagley, SJ Dunstan, AJ Husband, M Kopf, KI Matthaei, IA Ramshaw, RA Strugnell, IG Young, XY Tan

Book Chapter  |  1996

SALMONELLA-TYPHIMURIUM DISPLAYS NORMAL INVASION OF MICE WITH DEFECTIVE EPIDERMAL GROWTH-FACTOR RECEPTORS

A MCNEIL, SJ DUNSTAN, S CLARK, RA STRUGNELL

Journal article  |  1995  |  Infection and immunity

MOLECULAR CHARACTERIZATION OF THE STAPHYLOCOCCAL MULTIDRUG-RESISTANCE EXPORT PROTEIN QACC

IT PAULSEN, MH BROWN, SJ DUNSTAN, RA SKURRAY

Journal article  |  1995  |  Journal of bacteriology

Xpert Ultra and TB meningitis: advancing towards policy revision?

Maxine Caws, Sarah Jane Dunstan, Buddha Basnyat

Journal article  |  Annals of Infection