Paul Neeson

Intratumoral CD8 T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer.

Balaji Virassamy, Franco Caramia, Peter Savas, Sneha Sant, Jianan Wang, Susan N Christo, Ann Byrne, Kylie Clarke, Emmaline Brown, Zhi Ling Teo, Bianca von Scheidt, David Freestone, Luke C Gandolfo, Karsten Weber, Julia Teply-Szymanski, Ran Li, Stephen J Luen, Carsten Denkert, Sibylle Loibl, Olivia Lucas, et al.

Journal article  |  2023  |  Cancer Cell

CD8+ tumor-infiltrating lymphocytes with a tissue-resident memory T (TRM) cell phenotype are associated with favorable prognosis i..

Combining chemotherapy with CAR-T cell therapy in treating solid tumors

Arthur Xuan Wang, Xiao Jing Ong, Criselle D’Souza, Paul J Neeson, Joe Jiang Zhu

Journal article  |  2023  |  Frontiers in Immunology

Chemotherapy has long been a standard treatment for a wide range of malignancies, where patients typically undergo multiple rounds..

Single cell genomics and immune responses to cancer therapies

Paul J Neeson

Journal article  |  2023  |  Pathology

Salvage radical prostatectomy following 177Lu-PSMA-617 radioligand therapy in men with high-risk localized prostate cancer: Surgical aspects of the LuTectomy study

J O’Brien, O Alghazo, JP Buteau, R Eapen, P Jackson, C Mitchell, S Oon, L Mcintosh, K Chen, P Jenjitranant, G Sharma, M Scalzo, H Chalmers, AA Azad, S Sandhu, SG Williams, PJ Neeson, M Haskali, M Bressel, B Kelly, et al.

Journal article  |  2023  |  European Urology

Single cell genomics and immune responses to cancer therapies

Paul J Neeson

Journal article  |  2023  |  Pathology

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.

Kelden Richardson, Simon P Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D'Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A Bezman, Kirsten Todd, Hang Quach, David S Ritchie, Simon J Harrison, H Miles Prince, Joseph A Trapani, Misty R Jenkins, Paul A Beavis, Phillip K Darcy, Paul J Neeson

Journal article  |  2023  |  Haematologica

Patients with refractory relapsed multiple myeloma respond to combination treatment with elotuzumab and lenalidomide. The mechanis..

Cell signaling activation and extracellular matrix remodeling underpin glioma tumor microenvironment heterogeneity and organization

Marija Dinevska, Samuel S Widodo, Liam Furst, Lucero Cuzcano, Yitong Fang, Stefano Mangiola, Paul J Neeson, Phillip K Darcy, Robert G Ramsay, Ryan Hutchinson, Fabienne MacKay, Michael Christie, Stanley S Stylli, Theo Mantamadiotis

Journal article  |  2022  |  CELLULAR ONCOLOGY

PURPOSE: Tumor cells thrive by adapting to the signals in their microenvironment. To adapt, cancer cells activate signaling and tr..

Advances in CAR T cell immunotherapy for paediatric brain tumours

Padmashree Rao, Liam Furst, Deborah Meyran, Chelsea Mayoh, Paul J Neeson, Rachael Terry, Dong-Anh Khuong-Quang, Theo Mantamadiotis, Paul G Ekert

Journal article  |  2022  |  FRONTIERS IN ONCOLOGY

Brain tumours are the most common solid tumour in children and the leading cause of cancer related death in children. Current trea..

385 Engineering a TGF-β switch receptor enhances CAR-T cell function in a suppressive TGF-β-enriched tumor microenvironment

Joe Jiang Zhu, Criselle DSouza, Vicky Qin, Niko Thio, Michael Kershaw, Joe Trapani, Phillip Darcy, Paul Neeson

Conference Proceedings  |  2022  |  Regular and Young Investigator Award Abstracts

1442 Investigating the tumour immune microenvironment of breast implant associated anaplastic large cell lymphoma using single cell RNA sequencing

Harini de Silva, Niko Thio, Piers Blombery, Ella Thompson, Anand Deva, Miles Prince, Paul Neeson, Criselle DSouza

Conference Proceedings  |  2022  |  Regular and Young Investigator Award Abstracts