Terry O'Brien

Diffusion Imaging Reveals Sex Differences in the White Matter Following Sports-Related Concussion

David K Wright, Georgia F Symons, William T O'Brien, Stuart J McDonald, Akram Zamani, Brendan Major, Zhibin Chen, Daniel Costello, Rhys D Brady, Mujun Sun, Meng Law, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz

Journal article  |  2021  |  CEREBRAL CORTEX

Sports-related concussion (SRC) is a serious health concern. However, the temporal profile of neuropathophysiological changes afte..

Impact of the COVID-19 pandemic on people with epilepsy: Findings from the Brazilian arm of the COV-E study.

Maria Andraus, Jennifer Thorpe, Xin You Tai, Samantha Ashby, Asma Hallab, Ding Ding, Patricia Dugan, Piero Perucca, Daniel Costello, Jacqueline A French, Terence J O'Brien, Chantal Depondt, Danielle M Andrade, Robin Sengupta, Norman Delanty, Nathalie Jette, Charles R Newton, Martin J Brodie, Orrin Devinsky, J Helen Cross, et al.

Journal article  |  2021  |  Epilepsy Behav

The COVID-19 pandemic has had an unprecedented impact on people and healthcare services. The disruption to chronic illnesses, such..

The development and impact of cladribine on lymphoid and myeloid cells in multiple sclerosis

Veronica Tsin Fong Voo, Helmut Butzkueven, Jim Stankovich, Terence O'Brien, Mastura Monif

Journal article  |  2021  |  MULTIPLE SCLEROSIS AND RELATED DISORDERS

Cladribine is an approved selective immune reconstitution therapy for relapsing-remitting MS (RRMS). It was first developed and us..

Activation of the Protein Kinase R-Like Endoplasmic Reticulum Kinase (PERK) Pathway of the Unfolded Protein Response after Experimental Traumatic Brain Injury and Treatment with a PERK Inhibitor

Rhys D Brady, Stefanie Bird, Mujun Sun, Glenn R Yamakawa, Brendan P Major, Richelle Mychasiuk, Terence J O'Brien, Stuart J McDonald, Sandy R Shultz

Journal article  |  2021  |  NEUROTRAUMA REPORTS

Neurodegeneration after traumatic brain injury (TBI) is increasingly recognized as a key factor contributing to poor chronic outco..

Temporal profile and utility of serum neurofilament light in a rat model of mild traumatic brain injury

William T O'Brien, Louise Pham, Rhys D Brady, Jesse Bain, Glenn R Yamakawa, Mujun Sun, Richelle Mychasiuk, Terence J O'Brien, Mastura Monif, Sandy R Shultz, Stuart J McDonald

Journal article  |  2021  |  EXPERIMENTAL NEUROLOGY

There is a widely recognized need for blood biomarkers to assist clinical decisions surrounding mild traumatic brain injury (mTBI)..

Psychiatric and cognitive characteristics of older adults admitted to a Video-EEG monitoring (VEM) unit

Anthony Hew, Michael Lloyd, Genevieve Rayner, Alice Matson, Maria Rychkova, Rashida Ali, Toby Winton-Brown, Piero Perucca, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas, Samantha M Loi

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

OBJECTIVE: To compare the clinical, psychiatric, and cognitive characteristics of older with younger patients presenting to a vide..

White and Gray Matter Abnormalities in Australian Footballers With a History of Sports-Related Concussion: An MRI Study.

Brendan Major, Georgia F Symons, Ben Sinclair, William T O'Brien, Daniel Costello, David K Wright, Meaghan Clough, Steven Mutimer, Mujun Sun, Glenn R Yamakawa, Rhys D Brady, Michael J O'Sullivan, Richelle Mychasiuk, Stuart J McDonald, Terence J O'Brien, Meng Law, Scott Kolbe, Sandy R Shultz

Journal article  |  2021  |  Cereb Cortex

Sports-related concussion (SRC) is a form of mild traumatic brain injury that has been linked to long-term neurological abnormalit..

Study protocol for a phase II randomised, double-blind, placebo-controlled trial of perampanel as an antiepileptogenic treatment following acute stroke.

John-Paul Nicolo, Zhibin Chen, Bradford Moffat, David K Wright, Benjamin Sinclair, Rebecca Glarin, Andrew Neal, Vincent Thijs, Udaya Seneviratne, Bernard Yan, Geoffrey Cloud, Terence J O'Brien, Patrick Kwan

Journal article  |  2021  |  BMJ Open

INTRODUCTION: Stroke is a common cause of epilepsy that may be mediated via glutamate dysregulation. There is currently no evidenc..

Brief video enhances teacher trainees' knowledge of epilepsy

Frank JE Vajda, Terence J O'Brien, Janet E Graham, Alison A Hitchcock, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

PURPOSE: To assess the possible contribution of factors in additional to intrauterine anti-seizure medication (ASM) exposure in th..

The effect of injection time on rates of epileptogenic zone localization using SISCOM and STATISCOM

Gernot Hlauschek, Benjamin Sinclair, Benjamin Brinkmann, Joshua Fuge, Patrick Kwan, Terence J O'Brien, Lucy Vivash

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

BACKGROUND: The identification of hyperperfusion on ictal single-photon emission computed tomography (SPECT) scan is a technique f..