Terence O'Brien (MBBS Melb. MD Melb.
FRACP, FRCPE) is The James Stewart Professor of Medicine and Head of The Department of Medicine at The Royal Melbourne, and consultant neurologist. He is a medical specialist in neurology and clinical pharmacology, with particular expertise in epileptology, anti-epileptic drugs and in-vivo imaging in animal models and humans. He did his clinical and research training at St. Vincent’s and Royal Melbourne Hospitals in Melbourne, and then the Mayo Clinic, Rochester, Minnesota, USA (1995-1998). He leads a University Department Medicine embedded with one of Australia’s leading teaching hospitals which has a focus on translational research and research training, with particular strengths in Neurosciences, Infectious Diseases and Cancer. Under his leadership the Department has grown to be one of the largest such Department in the country with an annual research income of >10.5M, >80 PhD students and >100 undergraduate students. In his own research leads a large translational research team undertaking both basic studies, involving animal models, and clinical studies. He has published >300 peer-reviewed original papers in leading neurological, pharmacological and imaging journals, 6 other papers, 12 book chapters and >2000 abstracts. His work is highly cited (>8700 times, H-index 50). Competitive, peer-reviewed, research-grant funding obtained totals <30M, including being a PI on 14 NHMRC Project grants, a NHMRC Program Grant, 3 NHMRC Development Grants, a NHMRC Centre for Research Excellence Grant, two Victorian Neurotrauma Initiative Grants and three US competitive grant (NARSAD, Epilepsy Research Foundation & James S. McDonnell Foundation), and industry funding >5M. His research is broad based, covering both basic and clinical studies related to epilepsy, neuropharmacology and associated areas. The work has had two primary goals: First to better understand the determinants of treatment response in epilepsy, identify biomarkers for treatment outcomes – imaging, electrophysiological, genomic and clinical, and develop new treatment approaches. Second to investigate the fundamental neurobiological basis, and inter-relationship, of the neuropsychiatric co-morbidities present in many patients with epilepsy. He has developed an extensive network of collaborations both locally, nationally and internationally. He has head many national and international leadership positions in professional and scientific societies. This includes being a member of the Scientific Committee for the 28th International Epilepsy Conference in 2009, and Chair for the Asian and Oceanic Epilepsy Conference 2010, and is currently co-chair of the International League Against Epilepsy Task force on Translational Research and a member of the Neurobiology Commission.
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FEATURED Journal article
Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity
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19
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