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The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Cali..
Displaying the 7 most recent projects by Jason Mackenzie.
Internal Research Grant
Displaying the 73 most recent scholarly works by Jason Mackenzie.
West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles
Andrii Slonchak, Brian Clarke, Jason Mackenzie, Alberto Anastacio Amarilla, Yin Xiang Setoh, Alexander A Khromykh
Journal article | 2019 | BMC Genomics
The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Caliciviruses.
Daniel Enosi Tuipulotu, Tulio M Fumian, Natalie E Netzler, Jason M Mackenzie, Peter A White
Journal article | 2019 | Viruses
The widespread nature of calicivirus infections globally has a substantial impact on the health and well-being of humans and anima..
Downregulation of MHC Class I Expression by Influenza A and B Viruses
Marios Koutsakos, Hamish EG McWilliam, Turgut E Aktepe, Svenja Fritzlar, Patricia T Illing, Nicole A Mifsud, Anthony W Purcell, Steve Rockman, Patrick C Reading, Julian P Vivian, Jamie Rossjohn, Andrew G Brooks, Jason M Mackenzie, Justine D Mintern, Jose A Villadangos, Thi HO Nguyen, Katherine Kedzierska
Journal article | 2019 | Frontiers in Immunology
Determinants of Zika virus host tropism uncovered by deep mutational scanning
Yin Xiang Setoh, Alberto A Amarilla, Nias YG Peng, Rebecca E Griffiths, Julio Carrera, Morgan E Freney, Eri Nakayama, Shinya Ogawa, Daniel Watterson, Naphak Modhiran, Faith Elizabeth Nanyonga, Francisco J Torres, Andrii Slonchak, Parthiban Periasamy, Natalie A Prow, Bing Tang, Jessica Harrison, Jody Hobson-Peters, Thom Cuddihy, Justin Cooper-White, et al.
Journal article | 2019 | Nature Microbiology
Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
Hanne Dubois, Frederic Sorgeloos, Soroush T Sarvestani, Liesbet Martens, Yvan Saeys, Jason M Mackenzie, Mohamed Lamkanfi, Geert van Loo, Ian Goodfellow, Andy Wullaert
Journal article | 2019 | PLOS Pathogens
Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8( ) T Cell Recognition and Activation
Svenja Fritzlar, Sinthujan Jegaskanda, Turgut Esad Aktepe, Julia Emiley Prier, Lauren Elise Holz, Peter A White, Jason M Mackenzie
Journal article | 2018 | Journal of Virology
Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus
Susann Liebscher, Rebecca L Ambrose, Turgut E Aktepe, Andrea Mikulasova, Julia E Prier, Leah K Gillespie, Adam J Lopez-Denman, Thusitha WT Rupasinghe, Dedreia Tull, Malcolm J McConville, Jason M Mackenzie
Journal article | 2018 | PLOS Pathogens
A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection
Johanna E Fraser, Satoru Watanabe, Chunxiao Wang, Wing Ki Kitti Chan, Belinda Maher, Adam Lopez-Denman, Caroline Hick, Kylie M Wagstaff, Jason M Mackenzie, Patrick M Sexton, Subhash G Vasudevan, David A Jans
Journal article | 2014 | The Journal of Infectious Diseases
Crystal structure of the RNA polymerase domain of the West Nile Virus non-structural protein 5
Helene Malet, Marie-Pierre Egloff, Barbara Selisko, Rebecca E Butcher, Peter J Wright, Michael Roberts, Arnaud Gruez, Gerlind Sulzenbacher, Clemens Vonrhein, Gerard Bricogne, Jason M Mackenzie, Alexander A Khromykh, Andrew D Davidson, Bruno Canard
Journal article | 2007 | Journal of Biological Chemistry
Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum
Silke Stertz, Mike Reichelt, Jacomine Krijnse-Locker, Jason Mackenzie, Jeremy C Simpson, Otto Haller, Georg Kochs
Journal article | 2006 | Journal of Interferon and Cytokine Research
Comparisons of physical separation methods of Kunjin virus-induced membranes.
Min Kim, Jason M Mackenzie, Edwin G Westaway
Journal article | 2004 | Journal of Virological Methods
The two sets of connected membranes induced in Kunjin virus-infected cells are characterized by the presence of NS3 helicase/prote..
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