Diana Stojanovski

Interaction between host cell mitochondria and Coxiella burnetii

KQ Yek, D Stojanovski, HJ Newton

Journal article  |  2023  |  International review of cell and molecular biology

In order to successfully establish a replicative niche, intracellular bacterial pathogens must influence eukaryotic cell biology. ..

Mitochondrial biology and dysfunction in secondary mitochondrial disease

Megan J Baker, Jordan J Crameri, David R Thorburn, Ann E Frazier, Diana Stojanovski

Journal article  |  2022  |  OPEN BIOLOGY

Mitochondrial diseases are a broad, genetically heterogeneous class of metabolic disorders characterized by deficits in oxidative ..

Stimulating Mitochondrial Biogenesis with Deoxyribonucleosides Increases Functional Capacity in ECHS1-Deficient Cells

Harrison James Burgin, Jordan James Crameri, Diana Stojanovski, M Isabel G Lopez Sanchez, Mark Ziemann, Matthew McKenzie

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The lack of effective treatments for mitochondrial disease has seen the development of new approaches, including those that stimul..

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

Kenji M Fujihara, Bonnie Z Zhang, Thomas D Jackson, Moses O Ogunkola, Brunda Nijagal, Julia Milne, David A Sallman, Ching-Seng Ang, Iva Nikolic, Conor J Kearney, Simon J Hogg, Carlos S Cabalag, Vivien R Sutton, Sally Watt, Asuka T Fujihara, Joseph A Trapani, Kaylene J Simpson, Diana Stojanovski, Silke Leimkuhler, Sue Haupt, et al.

Journal article  |  2022  |  SCIENCE ADVANCES

The mechanism of action of eprenetapopt (APR-246, PRIMA-1MET) as an anticancer agent remains unresolved, although the clinical dev..

Premature Ovarian Insufficiency in CLPB Deficiency: Transcriptomic, Proteomic and Phenotypic Insights

Elena J Tucker, Megan J Baker, Daniella H Hock, Julia T Warren, Sylvie Jaillard, Katrina M Bell, Rajini Sreenivasan, Shabnam Bakhshalizadeh, Chloe A Hanna, Nikeisha J Caruana, Saskia B Wortmann, Shamima Rahman, Robert DS Pitceathly, Jean Donadieu, Aurelia Alimi, Vincent Launay, Paul Coppo, Sophie Christin-Maitre, Gorjana Robevska, Jocelyn van den Bergen, et al.

Journal article  |  2022  |  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CONTEXT: Premature ovarian insufficiency (POI) is a common form of female infertility that usually presents as an isolated conditi..

Loss of mitochondrial fatty acid beta-oxidation protein short-chain Enoyl-CoA hydratase disrupts oxidative phosphorylation protein complex stability and function

Harrison Burgin, Alice J Sharpe, Shuai Nie, Mark Ziemann, Jordan J Crameri, Diana Stojanovski, James Pitt, Akira Ohtake, Kei Murayama, Matthew McKenzie

Journal article  |  2022  |  FEBS JOURNAL

Short-chain enoyl-CoA hydratase 1 (ECHS1) is involved in the second step of mitochondrial fatty acid β-oxidation (FAO), catalysing..

Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module

Thomas D Jackson, Jordan J Crameri, Linden Muellner-Wong, Ann E Frazier, Catherine S Palmer, Luke E Formosa, Daniella H Hock, Kenji M Fujihara, Tegan Stait, Alice J Sharpe, David R Thorburn, Michael T Ryan, David A Stroud, Diana Stojanovski

Journal article  |  2022  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SignificanceMitochondria are double-membraned eukaryotic organelles that house the proteins required for generation of ATP, the en..

MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II Assembly

Mark Ziemann, Sze Chern Lim, Yilin Kang, Sona Samuel, Isabel Lopez Sanchez, Michael Gantier, Diana Stojanovski, Matthew McKenzie

Journal article  |  2021  |  JOURNAL OF MOLECULAR BIOLOGY

MicroRNA-101-3p (miR-101-3p) is a tumour suppressor that regulates cancer proliferation and apoptotic signalling. Loss of miR-101-..

Super-resolution microscopy reveals the arrangement of inner membrane protein complexes in mammalian mitochondria.

Catherine S Palmer, Jieqiong Lou, Betty Kouskousis, Elvis Pandzic, Alexander J Anderson, Yilin Kang, Elizabeth Hinde, Diana Stojanovski

Journal article  |  2021  |  J Cell Sci

The mitochondrial inner membrane is a protein-rich environment containing large multimeric complexes, including complexes of the m..

Super-resolution microscopy reveals the arrangement of inner membrane protein complexes in mammalian mitochondria

Catherine S Palmer, Jieqiong Lou, Betty Kouskousis, Elvis Pandzic, Alexander J Anderson, Yilin Kang, Elizabeth Hinde, Diana Stojanovski

Journal article  |  2021  |  JOURNAL OF CELL SCIENCE

The mitochondrial inner membrane is a protein-rich environment containing large multimeric complexes, including complexes of the m..