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Prof

Danny Hatters

Professor
Biochemistry And Molecular Biology
polyglutamine
fluorescence
Protein aggregation
Huntington's Disease
Motor Neuron Disease
science & technology
life sciences & biomedicine
humans
biochemistry & molecular biology
Danny Hatters's Profile Picture
Prof

Danny Hatters

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Protein conformations in cells. New techniques. Protein misfolding and aggregation.
Danny Hatters's Profile Picture
Prof

Danny Hatters

 

Danny Hatters runs a program exploring how proteins change conformation in cells as part of normal and pathogenic processes, including those associated with misfolding and aggregation. Key elements of this research include the development and application of new fluorescence -based probes and biosensors to view protein dynamics in cells.

His major area of research is in Huntington's Disease with other programs in motor neuron disease and fundamental biology of protein-ligand associations as part of cellular mechanisms. He completed his PhD at the University of Melbourne in 2002. He then did a post doc at the Gladstone Institutes/University of California, San Francisco under the mentorship of Dr Karl Weisgraber for 5 years until 2007. There he studied how three variants of apolipoprotein E, apoE2, apoE3 and apoE4 differ in their conformation and biophysical properties as a basis for understanding the mechanisms underlying the elevated risk that the apoE4 isoform confers for Alzheimer's disease. In April 2007, he returned to Melbourne to take up a CR Roper Fellowship position in the Department of Biochemistry and Molecular Biology. In 2009 he was awarded the Grimwade Fellowship to continue developing his own research program focusing on how protein conformations lead to cellular dysfunction and disease. In 2012, he was awarded an ARC Future Fellowship. In 2019 he was awarded an NHMRC Senior Research Fellowship.

Projects

Displaying the 22 most recent projects by Danny Hatters.

22

Projects

Project Types


17

Research Grant


4

Internal Research Grant


1

Research Contracts


Scholarly Works

Displaying the 90 most recent scholarly works by Danny Hatters.

Honours, Awards and Fellowships

2015

McAulay-Hope Prize for Original Biophysics

Australian Society for Biophysics

2009

Applied Biosystems Edman Award

ASBMB

2006

Boomerang Award

ASBMB

3

Awards

Credentials

Positions


Professor

Biochemistry And Molecular Biology

Secretary Of Meeting

Lorne Conference on Protein Structure and Function

Education


PhD

University of Melbourne

Bachelor of science (Hons)

University of Melbourne