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A/Prof

Michael Hildebrand

Principal Research Fellow
Medicine - Austin Health
Genes
Linkage Analysis
Sequencing
science & technology
life sciences & biomedicine
humans
male
female
neurosciences & neurology
Michael Hildebrand's Profile Picture
A/Prof

Michael Hildebrand

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Epilepsy
Michael Hildebrand's Profile Picture
A/Prof

Michael Hildebrand

 

I am a neurogeneticist with international research experience and collaborations who completed my PhD in late 2006 (University of Melbourne). I head the Translational Neurogenetics Laboratory in the Epilepsy Research Centre at the Melbourne Brain Centre, Austin Hospital, and am currently supported by with the supported of by a NHMRC Centre of Research Excellence in Speech and Language Neurobiology (APP1116976), and NHMRC Project Grants on detection of somatic mutations in sporadic epilepsy (APP1129054) and improving diagnosis, prognosis and clinical care in childhood speech disorders (APP1127144).

The focus of my research is to understand the basic neurobiology of human epilepsy and speech disorders, and translate this knowledge into improved treatment of patients. Further information about my research is available on my laboratory homepage: http://medicine.unimelb.edu.au/research-groups/medicine-and-radiology-research/austin-hospital/translational-neurogenetics-laboratory and the Epilepsy Research Centre homepage: http://medicine.unimelb.edu.au/research-groups/medicine-and-radiology-research/austin-hospital/epilepsy-research-centre. My achievements include:

• H-index 37, > 4,400 citations
• 96 research papers including 34 first, 22 corresponding and 10 last author contributions
• Discovered: 10 speech disorder genes (Neurology - accepted Dec 2019, Mol Psych 2019), 5 epilepsy genes (e.g. AJHG 2016, Nat Genet 2013/2015), 5 deafness genes (PNAS 2008/2011, AJHG 2009/2011, Nat Comm 2011), and 1 male infertility gene (AJHG 2009, EJHG 2010) • Created deafness therapies (JARO 2005, Mol Ther 2008, Hear Res 2011)
• Developed the first clinical gene panel for deafness (PNAS 2010)
• Designed the first clinical phenotype filter for deafness (Genet Med 2008, AJMG 2009)
• Productive 5 year international postdoc (University of Iowa, United States, 2006-2011)
• Contributed to grants totalling >

0 million (~
.74M as CIA) - Epilepsy Foundation Grant, CIA (2020-2024)
• NHMRC CRE Grant APP1116976, CIC (2017-2021)
• NHMRC Project Grant APP1129054, CIB (2017-2020)
• NHMRC Project Grant APP1127144 CIB (2017-2019)
• NHMRC Project Grant APP1079058, CIA (2015-2017)
• NHMRC Project Grant APP1067081, CIB (2014-2016)
• NHMRC Project Grant APP1050161, CIC (2013-2015)
• ARC Discovery Project 120100285, CIC (2012-2014)
• March of Dimes Grant, CI (2015-2017)
• NHMRC RD Wright CDF Fellowship APP1063799, CIA (2014-2018)
• NHMRC CJ Martin Fellowship APP546493, CIA (2009-2013)
• MNI Grant, CIA, (2014)
• MNI Fellowship, CIA (2014)
• APA (2002-2005)
• Dean's Honours List (2002)
• Lecturer in Neurosciences PhD Program University of Melbourne (2012-2020)
• PhD/Honours/UROP Student (x15) co-supervisor/examiner (2006-2020)
• Postdoc (x3) co-mentor (2012-2020)
• Lab head (> 7 year) managing 7 staff (4xRA/3xTA; 2012-2020)

Projects

Displaying the 10 most recent projects by Michael Hildebrand.

16

Projects

Project Types


14

Research Grant


1

Internal Research Grant


1

Research Contracts


Additional Information

2020-2024 Epilepsy Foundation, Australian Epilepsy Research Fund Grant Scheme, A Clinical Liquid Biopsy to Diagnose Epilepsy ($224,640 AUD) CIA: A/Prof. Michael S. Hildebrand, CIB Prof. Samuel Berkovic, CIC Prof. Melanie Bahlo, CID Prof. Ingrid Scheffer, CIE A/Prof. Richard Leventer

2019 Sir Edward Dunlop Medical Research Foundation Grant, Somatic Mutation as a Cause of Severe Focal Epilepsy ($20,000 AUD) CIA: Dr. Michael S Hildebrand

2018 University of Melbourne, MDHS Research Fellowship, (

10,000 AUD) CIA: Dr. Michael S.Hildebrand

2017 University of Melbourne, MDHS Large Equipment Grant, ($59,997 AUD) CIA: Dr. Michael S.Hildebrand

2017-2020 NHMRC Project Grant APP1129054, Detection of Somatic Mutations in Sporadic Epilepsies, University of Melbourne (
,256,165 AUD) CIA: Prof. Samuel F Berkovic, CIB: Dr. Michael S Hildebrand, CIC: Dr. Slave Petrovski, CID: Dr. Snezana Maljevic

2017-2019 NHMRC Project Grant APP1127144, Neurobiology of childhood speech disorders: improving diagnosis, prognosis & clinical care, Murdoch Childrens Research Institute ($994,575 AUD) CIA: A/Prof. Angela Morgan, CIB: Dr. Michael S Hildebrand, CIC: Prof. Simon Fisher, CID: Dr. Frederique Liegeois

2017-2021 NHMRC CRE in Speech and Language Neurobiology (CRE- SLANG) APP1116976, Murdoch Childrens Research Institute ($2,491,340 AUD) CIA: A/Prof. Angela Morgan, CIB: Prof. Ingrid Scheffer, CIC: Michael S. Hildebrand, CID: Prof. Melanie Bahlo, CIE Prof. Alan Connelly, CIF: Prof. David Amor, CIG: Prof. Sheena Reilly, CIH: Prof. Simon Fisher, CII: Dr. Frederique Liegeois

2016 Sir Edward Dunlop Medical Research Foundation Grant, Zinc and seizures, University of Melbourne ($20,000 AUD) CIA: Dr. Michael S Hildebrand

2015-2017 March of Dimes Grant, Murdoch Childrens Research Institute ($201,542 AUD) CI: Dr. Angela Morgan, CI: Prof. Alan Connelly, CI: Dr. Frederique Liegeois, CI: A/Prof. Melanie Bahlo, CI: Dr. Michael S Hildebrand, CI: Prof. Ingrid Scheffer

2015 University of Melbourne, MDHS Establishment Grant, ($35,000 AUD) CIA: Dr. Michael S.Hildebrand

2014 Melbourne Neuroscience Institute Research Fellowship, University of Melbourne ($33,333 AUD) CIA: Dr. Michael S Hildebrand

2014 Melbourne Neuroscience Institute Interdisciplinary Seed Funding Scheme, University of Melbourne($40,000 AUD) CIA: Dr. Michael S Hildebrand, CIB: Dr. Angela Morgan, CIC: Prof. Alan Connelly, CID: Prof. Ingrid Scheffer

2013 Austin Medical Research Foundation (AMRF) Grant-In-Aid of Medical Research, University of Melbourne (
0,000 AUD) CIA: Dr. Michael S. Hildebrand

2012-2014 Australian Research Council (ARC), Discovery Project DP120100285, University of Melbourne ($510,000 AUD) CI: Prof. Ingrid. E Scheffer, CI: Dr. Angela T. Morgan, CI: Dr. Michael S. Hildebrand

2012-2016 National Institutes of Health (NIH) R01 Grant PAR-11-003, Optimizing High-Throughput, Low-Cost Clinical Diagnostic Genetic Testing for Deafness, University of Iowa, USA ($2.5 million USD) PI: Dr. Richard J.H. Smith

2010-2011 The National Organization for Hearing Research (NOHR) Stria Vascularis Research Grant, Department of Otolaryngology, University of Iowa, Iowa,
USA ($50,000 USD) PI: Prof. Richard J.H. Smith

2009-2011 Royal National Institute for Deaf People (RNID) International Grant, RNA interference protects against hereditary hearing loss, Department of Otolaryngology, University of Iowa, Iowa, USA (₤97,500 GBP;
65,816 USD) PI: Prof. Richard J.H. Smith

2006-2008 Postdoctoral Fellowship, National Institutes of Health (NIH), R01 Grant DC003544, Autosomal Dominant Non-Syndromic Hearing Loss. Department of Otolaryngology, University of Iowa, Iowa, USA ($2.1 million USD) PI: Prof. Richard J.H. Smith

Scholarly Works

Displaying the 10 most recent scholarly works by Michael Hildebrand.

Honours, Awards and Fellowships

2014

NHMRCF - NHMRC Fellowship


2009

CJMARTIN - C.J. Martin Research Fellowship (National Health & Medical Research Council, Australia)


2

Awards

Credentials

Positions

Positions


Principal Research Fellow

Medicine - Austin Health

Trainee

American Epilepsy Society

Trainee

American Society of Human Genetics

Ordinary Membership

Australian Society for Medical Research

Education

Education


Doctor of Philosophy

University of Melbourne

Bachelor of Science (Hons)

University of Melbourne

Bachelor of Biomedical Science

University of Melbourne

Links

Links