Martin Ashdown

Shifting the Immune-Suppressive to Predominant Immune-Stimulatory Radiation Effects by SBRT-PArtial Tumor Irradiation Targeting HYpoxic Segment (SBRT-PATHY)

Slavisa Tubin, Seema Gupta, Michael Grusch, Helmuth H Popper, Luka Brcic, Martin L Ashdown, Samir N Khleif, Barbara Peter-Vorosmarty, Martin Hyden, Simone Negrini, Piero Fossati, Eugen Hug

Journal article  |  2021  |  CANCERS

Radiation-induced immune-mediated abscopal effects (AE) of conventional radiotherapy are very rare. Whole-tumor irradiation leads ..

Chemotherapy for Late-Stage Cancer Patients: Meta-Analysis of Complete Response Rates.

Martin L Ashdown, Andrew P Robinson, Steven L Yatomi-Clarke, M Luisa Ashdown, Andrew Allison, Derek Abbott, Svetomir N Markovic, Brendon J Coventry

Journal article  |  2015  |  F1000Res

Complete response (CR) rates reported for cytotoxic chemotherapy for late-stage cancer patients are generally low, with few except..

Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation.

Brendon J Coventry, Martin L Ashdown

Journal article  |  2012  |  Cancer Manag Res

Over 50 years of cancer therapy history reveals complete clinical responses (CRs) from remarkably divergent forms of therapies (eg..

Fluctuation of systemic immunity in melanoma and implications for timing of therapy.

Alexey A Leontovich, Roxana S Dronca, Vera J Suman, Martin L Ashdown, Wendy K Nevala, Michael A Thompson, Andrew Robinson, Lisa A Kottschade, Judith S Kaur, Robert R McWilliams, Leonid V Ivanov, Gary A Croghan, Svetomir N Markovic

Journal article  |  2012  |  Front Biosci (Elite Ed)

Evidence suggests that immunological response in chronic inflammation is dynamic, oscillating between active immunity and toleranc..

CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?

Brendon J Coventry, Martin L Ashdown, Michael A Quinn, Svetomir N Markovic, Steven L Yatomi-Clarke, Andrew P Robinson

Journal article  |  2009  |  JOURNAL OF TRANSLATIONAL MEDICINE

The search for a suitable biomarker which indicates immune system responses in cancer patients has been long and arduous, but a wi..

Recent patents relating to diagnostic advances in age related macular degeneration (AMD).

Stuart Cantsilieris, Maria Schache, M Luisa Ashdown, Paul N Baird

Journal article  |  2009  |  Recent Pat DNA Gene Seq

Age Related Macular Degeneration (AMD) is a complex neurodegenerative disorder accounting for 50% of blind registrations in the we..