Partha Das

Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase

Maheshi Udugama, Benjamin Vinod, F Lyn Chan, Linda Hii, Andrew Garvie, Philippe Collas, Paul Kalitsis, David Steer, Partha P Das, Pratibha Tripathi, Jeffrey R Mann, Hsiao PJ Voon, Lee H Wong

Journal article  |  2022  |  NUCLEIC ACIDS RESEARCH

Histone H3.3 is an H3 variant which differs from the canonical H3.1/2 at four residues, including a serine residue at position 31 ..

TINC-A Method to Dissect Regulatory Complexes at Single-Locus Resolution-Reveals an Extensive Protein Complex at the Nanog Promoter

Anja S Knaupp, Monika Mohenska, Michael R Larcombe, Ethan Ford, Sue Mei Lim, Kayla Wong, Joseph Chen, Jaber Firas, Cheng Huang, Xiaodong Liu, Nguyen Trung, Yu BY Sun, Melissa L Holmes, Pratibha Tripathi, Jahnvi Pflueger, Fernando J Rossello, Jan Schroder, Kathryn C Davidson, Christian M Nefzger, Partha P Das, et al.

Journal article  |  2020  |  STEM CELL REPORTS

Cellular identity is ultimately dictated by the interaction of transcription factors with regulatory elements (REs) to control gen..

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs

Matthew C Canver, Pratibha Tripathi, Michael J Bullen, Moshe Olshansky, Yogesh Kumar, Lee H Wong, Stephen J Turner, Samuel Lessard, Luca Pinello, Stuart H Orkin, Partha Pratim Das

Journal article  |  2020  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Regulatory elements (REs) consist of enhancers and promoters that occupy a significant portion of the noncoding genome and control..

Reprogramming roadmap reveals route to human induced trophoblast stem cells

Xiaodong Liu, John F Ouyang, Fernando J Rossello, Jia Ping Tan, Kathryn C Davidson, Daniela S Valdes, Jan Schroeder, Yu BY Sun, Joseph Chen, Anja S Knaupp, Guizhi Sun, Hun S Chy, Ziyi Huang, Jahnvi Pflueger, Jaber Firas, Vincent Tano, Sam Buckberry, Jacob M Paynter, Michael R Larcombe, Daniel Poppe, et al.

Journal article  |  2020  |  Nature

The reprogramming of human somatic cells to primed or naive induced pluripotent stem cells recapitulates the stages of early embry..

ABCA12 regulates insulin secretion from beta-cells

Gloria M Ursino, Ying Fu, Denny L Cottle, Nigora Mukhamedova, Lynelle K Jones, Hann Low, Ming Shen Tham, Wan Jun Gan, Natalie A Mellett, Partha P Das, Jacquelyn M Weir, Michael Ditiatkovski, Stacey Fynch, Peter Thorn, Helen E Thomas, Peter J Meikle, Helena C Parkington, Ian M Smyth, Dmitri Sviridov

Journal article  |  2020  |  EMBO REPORTS

Dysregulation of lipid homeostasis is intimately associated with defects in insulin secretion, a key feature of type 2 diabetes. H..

Is There a Change in Electroconvulsive Therapy Practice Following the New Mental Health Act 2014 in Victoria? A Study at a Metropolitan Mental Health Service

Partha Das, Karuppiah Jagadheesan, Frances Walker, Vinay Lakra, Nicola T Lautenschlager, Angelo Ferraro, Devapriya Rudolph

Journal article  |  2019  |  JOURNAL OF ECT

OBJECTIVES: The main objective of our study was to examine whether there has been any change to electroconvulsive therapy (ECT) pr..