Zhibin Chen

Diffusion Imaging Reveals Sex Differences in the White Matter Following Sports-Related Concussion

David K Wright, Georgia F Symons, William T O'Brien, Stuart J McDonald, Akram Zamani, Brendan Major, Zhibin Chen, Daniel Costello, Rhys D Brady, Mujun Sun, Meng Law, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz

Journal article  |  2021  |  CEREBRAL CORTEX

Sports-related concussion (SRC) is a serious health concern. However, the temporal profile of neuropathophysiological changes afte..

Machine learning models for decision support in epilepsy management: A critical review

Eliot D Smolyansky, Haris Hakeem, Zongyuan Ge, Zhibin Chen, Patrick Kwan

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

PURPOSE: There remain major challenges for the clinician in managing patients with epilepsy effectively. Choosing anti-seizure med..

One step closer towards personalized epilepsy management.

Zhibin Chen, Alison Anderson, Zongyuan Ge, Patrick Kwan

Journal article  |  2021  |  Brain

This scientific commentary refers to ‘Towards realizing the vision of precision medicine: AI based prediction of clinical drug res..

Study protocol for a phase II randomised, double-blind, placebo-controlled trial of perampanel as an antiepileptogenic treatment following acute stroke.

John-Paul Nicolo, Zhibin Chen, Bradford Moffat, David K Wright, Benjamin Sinclair, Rebecca Glarin, Andrew Neal, Vincent Thijs, Udaya Seneviratne, Bernard Yan, Geoffrey Cloud, Terence J O'Brien, Patrick Kwan

Journal article  |  2021  |  BMJ Open

INTRODUCTION: Stroke is a common cause of epilepsy that may be mediated via glutamate dysregulation. There is currently no evidenc..

Development and validation of a clinical score to predict late seizures after intracerebral hemorrhage in Chinese

Yan Wang, Zhen Li, Xiaosai Zhang, Zhibin Chen, Dongmei Li, Wenxian Chen, Jiamei Gu, Dongyun Sun, Ting Rong, Patrick Kwan

Journal article  |  2021  |  EPILEPSY RESEARCH

BACKGROUND: Seizures are a frequent complication after intracerebral hemorrhage (ICH). The CAVE score was developed in Europeans t..

Short- and long-term outcomes of immediate and delayed treatment in epilepsy diagnosed after one or multiple seizures

Sameer Sharma, Zhibin Chen, Maria Rychkova, John Dunne, Judy Lee, Nicholas Lawn, Patrick Kwan

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

OBJECTIVES: To compare the outcomes between immediate and deferred treatments in patients diagnosed after one or multiple (two or ..

Predictors of New-Onset Epilepsy in People With Younger-Onset Neurocognitive Disorders

Xinshi Wang, Samantha M Loi, Emma Foster, Zhibin Chen, Dennis Velakoulis, Patrick Kwan

Journal article  |  2021  |  FRONTIERS IN AGING NEUROSCIENCE

Objective: People with neurocognitive disorders (NCDs) have an increased risk of epilepsy. However, most studies investigating the..

Elevated Serum Interleukin-1 beta Levels in Male, but not Female, Collision Sport Athletes with a Concussion History

William T O'Brien, Georgia F Symons, Jesse Bain, Brendan P Major, Daniel M Costello, Mujun Sun, Joshua S Kimpton, Zhibin Chen, Rhys D Brady, Richelle Mychasiuk, Terence J O'Brien, Mastura Monif, Sandy R Shultz, Stuart J McDonald

Journal article  |  2021  |  JOURNAL OF NEUROTRAUMA

It is increasingly reported that a history of concussion may be associated with chronic deleterious consequences. While the pathop..

Sex Differences in the Risk of Cutaneous Adverse Drug Reactions Induced by Antiseizure Medications: A Systematic Review and Meta-analysis

Israa Alfares, Muhammad Shahid Javaid, Zhibin Chen, Alison Anderson, Ana Antonic-Baker, Patrick Kwan

Journal article  |  2021  |  CNS DRUGS

BACKGROUND: Cutaneous adverse drug reactions (cADRs) are one of the most common, severe, and life-threatening types of adverse rea..

Prolonged elevation of serum neurofilament light after concussion in male Australian football players

Stuart J McDonald, William T O'Brien, Georgia F Symons, Zhibin Chen, Jesse Bain, Brendan P Major, Daniel Costello, Glenn Yamakawa, Mujun Sun, Rhys D Brady, Biswadev Mitra, Richelle Mychasiuk, Terence J O'Brien, Sandy R Shultz

Journal article  |  2021  |  BIOMARKER RESEARCH

BACKGROUND: Biomarkers that can objectively guide the diagnosis of sports-related concussion, and consequent return-to-play decisi..