Martin O'Hely

Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring autism spectrum disorder symptoms in early life: A birth cohort study

Sarah Thomson, Katherine Drummond, Martin O'Hely, Christos Symeonides, Chitra Chandran, Toby Mansell, Richard Saffery, Peter Sly, Jochen Mueller, Peter Vuillermin, Anne-Louise Ponsonby, Infant Study Investigator Group Barwon

Journal article  |  2022  |  ENVIRONMENT INTERNATIONAL

Prenatal phthalate exposure has previously been linked to the development of autism spectrum disorder (ASD). However, the underlyi..

Household size, T regulatory cell development, and early allergic disease: a birth cohort study

Anne-Louise Ponsonby, Fiona Collier, Martin O'Hely, Mimi LK Tang, Sarath Ranganathan, Lawrence Gray, Ellen Morwitch, Richard Saffery, David Burgner, Terence Dwyer, Peter D Sly, Leonard C Harrison, Peter Vuillermin

Journal article  |  2022  |  PEDIATRIC ALLERGY AND IMMUNOLOGY

BACKGROUND: Children born to larger households have less allergic disease. T regulatory cell (Treg) development may be a relevant ..

Infant inflammation predicts childhood emotional and behavioral problems and partially mediates socioeconomic disadvantage

Cindy Pham, Siroon Bekkering, Martin O'Hely, David Burgner, Sarah Thomson, Peter Vuillermin, Fiona Collier, Wolfgang Marx, Toby Mansell, Christos Symeonides, Peter D Sly, Mimi LK Tang, Richard Saffery, Anne-Louise Ponsonby, BIS Investigator Group BIS Invest Grp

Journal article  |  2022  |  BRAIN BEHAVIOR AND IMMUNITY

BACKGROUND: Emotional and behavioral problems (EBP) are common in children. Environmental factors like socioeconomic disadvantage ..

Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles in infancy: a population-based cohort study

Toby Mansell, Richard Saffery, Satvika Burugupalli, Anne-Louise Ponsonby, Mimi LK Tang, Martin O'Hely, Siroon Bekkering, Adam Alexander T Smith, Rebecca Rowland, Sarath Ranganathan, Peter D Sly, Peter Vuillermin, Fiona Collier, Peter Meikle, David Burgner, Infant Study Investigator Grp Barwon

Journal article  |  2022  |  ELIFE

BACKGROUND: The risk of adult onset cardiovascular and metabolic (cardiometabolic) disease accrues from early life. Infection is u..

Shortened Infant Telomere Length Is Associated with Attention Deficit/Hyperactivity Disorder Symptoms in Children at Age Two Years: A Birth Cohort Study

Cindy Pham, Regan Vryer, Martin O'Hely, Toby Mansell, David Burgner, Fiona Collier, Christos Symeonides, Mimi LK Tang, Peter Vuillermin, Lawrence Gray, Richard Saffery, Anne-Louise Ponsonby

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Environmental factors can accelerate telomere length (TL) attrition. Shortened TL is linked to attention deficit/hyperactivity dis..

A Pathway-Based Genetic Score for Oxidative Stress: An Indicator of Host Vulnerability to Phthalate-Associated Adverse Neurodevelopment

Samuel Tanner, Sarah Thomson, Katherine Drummond, Martin O'Hely, Christos Symeonides, Toby Mansell, Richard Saffery, Peter D Sly, Fiona Collier, David Burgner, Eva J Sugeng, Terence Dwyer, Peter Vuillermin, Anne-Louise Ponsonby

Journal article  |  2022  |  ANTIOXIDANTS

The developing brain is highly sensitive to environmental disturbances, and adverse exposures can act through oxidative stress. Gi..

A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

Journal article  |  2022  |  MOLECULAR PSYCHIATRY

The emerging understanding of gut microbiota as 'metabolic machinery' influencing many aspects of physiology has gained substantia..

Innate Immune Activation and Circulating Inflammatory Markers in Preschool Children

Fiona Collier, Cerys Chau, Toby Mansell, Keshav Faye-Chauhan, Peter Vuillermin, Anne-Louise Ponsonby, Richard Saffery, Mimi LK Tang, Martin O'Hely, John Carlin, Lawrence EK Gray, Siroon Bekkering, David Burgner

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Early childhood is characterised by repeated infectious exposures that result in inflammatory responses by the innate immune syste..

Early life environmental factors associated with autism spectrum disorder symptoms in children at age 2 years: A birth cohort study

Cindy Pham, Christos Symeonides, Martin O'Hely, Peter D Sly, Luke D Knibbs, Sarah Thomson, Peter Vuillermin, Richard Saffery, Anne-Louise Ponsonby

Journal article  |  2022  |  AUTISM

Mounting evidence indicates the contribution of early life environmental factors in autism spectrum disorder. We aim to report the..

Maternal inflammatory and omega-3 fatty acid pathways mediate the association between socioeconomic disadvantage and childhood cognition

Wolfgang Marx, Sarah Thomson, Martin O'Hely, Christos Symeonides, Fiona Collier, Mimi LK Tang, Amy Loughman, David Burgner, Richard Saffery, Cindy Pham, Toby Mansell, Peter D Sly, Peter Vuillermin, Sarath Ranganathan, Anne-Louise Ponsonby

Journal article  |  2021  |  BRAIN BEHAVIOR AND IMMUNITY

Poor cognitive outcomes in early childhood predict poor educational outcomes and diminished health over the life course. We sought..