Yen Ying Lim

Influence of Comorbidity of Cerebrovascular Disease and Amyloid-β on Alzheimer's Disease.

Nawaf Yassi, Saima Hilal, Ying Xia, Yen Ying Lim, Rosie Watson, Hugo Kuijf, Christopher Fowler, Paul Yates, Paul Maruff, Ralph Martins, David Ames, Christopher Chen, Christopher C Rowe, Victor L Villemagne, Olivier Salvado, Patricia M Desmond, Colin L Masters

Journal article  |  2020  |  Journal of Alzheimer's Disease

BACKGROUND: Quantifying the contribution of cerebrovascular disease to the clinical and pathological profile of Alzheimer's diseas..

Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance.

Christa Dang, Nawaf Yassi, Karra D Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R Sohrabi, James D Doecke, Jurgen Fripp, Olivier Salvado, Peter J Snyder, Michael Weinborn, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, undefined AIBL Research Group

Journal article  |  2019  |  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Introduction: Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration..

Visual Paired Associate Learning Deficits Associated With Elevated Beta-Amyloid in Cognitively Normal Older Adults

Jenalle E Baker, Robert H Pietrzak, Simon M Laws, David Ames, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, Yen Ying Lim

Journal article  |  2019  |  Neuropsychology

OBJECTIVE: Previous studies have shown that paired associate learning (PAL), a type of episodic memory, is impaired in early Alzhe..

Use of an experimental language acquisition paradigm for standardized neuropsychological assessment of learning: A pilot study in young and older adults

Jenalle E Baker, Loren Bruns, Jason Hassenstab, Colin L Masters, Paul Maruff, Yen Ying Lim

Journal article  |  2019  |  Journal of Clinical and Experimental Neuropsychology

Determining clinically meaningful decline in preclinical Alzheimer disease

Philip S Insel, Michael Weiner, R Scott Mackin, Elizabeth Mormino, Yen Ying Lim, Erik Stomrud, Sebastian Palmqvist, Colin L Masters, Paul T Maruff, Oskar Hansson, Niklas Mattsson

Journal article  |  2019  |  Neurology

OBJECTIVE: To determine the time required for a preclinical Alzheimer disease population to decline in a meaningful way, use estim..

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid beta-Associated Cognitive Decline in Older Adults

Christa Dang, Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M Laws, Nawaf Yassi, Martha Hickey, Stephanie R Rainey-Smith, Joanne Robertson, Christopher C Rowe, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2019  |  Archives of Clinical Neuropsychology

Objective: To prospectively examine 8-year risk of clinical disease progression to mild cognitive impairment (MCI)/dementia in old..

COMT val158met is not associated with Aβ-amyloid and APOE ε4 related cognitive decline in cognitively normal older adults.

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Hamid R Sohrabi, Madeline Peretti, Yen Ying Lim, Michael Weinborn, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article  |  2019  |  IBRO Reports

The non-synonymous single nucleotide polymorphism (SNP), Val158Met within the Catechol-O-methyltransferase (COMT) gene has been as..

Cognitive Decline Over 18 Months in Patients With Mild Cognitive Impairment or Dementia due to Alzheimer's Disease

Yen Ying Lim, Ellen Huang, Jessica Kong, Paul Maruff, Judith Jaeger, Elena Ratti

Conference Proceedings  |  2019  |  NEUROLOGY

Klotho allele status is not associated with A beta and APOE epsilon 4-related cognitive decline in preclinical Alzheimer's disease

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Yen Ying Lim, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article  |  2019  |  Neurobiology of Aging

Mechanisms underlying resilience in ageing.

Yaakov Stern, Gaël Chételat, Christian Habeck, Eider M Arenaza-Urquijo, Prashanthi Vemuri, Ainara Estanga, David Bartrés-Faz, Marc Cantillon, Sean AP Clouston, Jeremy A Elman, Brian T Gold, Richard Jones, Gerd Kempermann, Yen Ying Lim, Anita van Loenhoud, Pablo Martínez-Lage, Silvia Morbelli, Ozioma Okonkwo, Rik Ossenkoppele, Corinne Pettigrew, et al.

Journal article  |  2019  |  Nature Reviews Neuroscience

Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid beta load in preclinical Alzheimer's disease

Lisa Bransby, Yen Ying Lim, David Ames, Christopher Fowler, Joanne Roberston, Karra Harrington, Peter J Snyder, Victor L Villemagne, Olivier Salvado, Colin L Masters, Paul Maruff

Journal article  |  2019  |  Journal of Clinical and Experimental Neuropsychology

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, et al.

Journal article  |  2019  |  Molecular Psychiatry

In Alzheimer's disease (AD), a single-nucleotide polymorphism in the gene encoding brain-derived neurotrophic factor (BDNFVal66Met..

The Healthy Brain Project: An Online Platform for the Recruitment, Assessment, and Monitoring of Middle-Aged Adults at Risk of Developing Alzheimer's Disease

Yen Ying Lim, Nawaf Yassi, Lisa Bransby, Michael Properzi, Rachel Buckley

Journal article  |  2019  |  Journal of Alzheimer's Disease

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease

Tenielle Porter, Samantha C Burnham, Greg Savage, Yen Ying Lim, Paul Maruff, Lidija Milicic, Madeline Peretti, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, Kevin Taddei, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article  |  2018  |  Frontiers in Aging Neuroscience

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease

Karra D Harrington, Adrian Schembri, Yen Ying Lim, Christa Dang, David Ames, Jason Hassenstab, Simon M Laws, Stephanie Rainey-Smith, Joanne Robertson, Christopher C Rowe, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Neurobiology of Aging

The effect of preclinical Alzheimer's disease on age-related changes in intelligence in cognitively normal older adults

Karra D Harrington, Christa Dang, Yen Ying Lim, David Ames, Simon M Laws, Robert H Pietrzak, Stephanie Rainey-Smith, Joanne Robertson, Christopher C Rowe, Olivier Salvado, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Intelligence

Sex, amyloid, and APOE epsilon 4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts

Rachel F Buckley, Elizabeth C Mormino, Rebecca E Amariglio, Michael J Properzi, Jennifer S Rabin, Yen Ying Lim, Kathryn V Papp, Heidi IL Jacobs, Samantha Burnham, Bernard J Hanseeuw, Vincent Dore, Annette Dobson, Colin L Masters, Michael Waller, Christopher C Rowe, Paul Maruff, Michael C Donohue, Dorene M Rentz, Dylan Kirn, Trey Hedden, et al.

Journal article  |  2018  |  Alzheimer's & Dementia

Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease

Yen Ying Lim, Jason Hassenstab, Alison Goate, Anne M Fagan, Tammie LS Benzinger, Carlos Cruchaga, Eric McDade, Jasmeer Chhatwal, Johannes Levin, Martin R Farlow, Neill R Graff-Radford, Christoph Laske, Colin L Masters, Stephen Salloway, Peter Schofield, John C Morris, Paul Maruff, Randall J Bateman

Journal article  |  2018  |  Annals of Neurology

Combined neuropathological pathways account for age-related risk of dementia.

Melinda C Power, Elizabeth Mormino, Anja Soldan, Bryan D James, Lei Yu, Nicole M Armstrong, Katherine J Bangen, Lisa Delano-Wood, Melissa Lamar, Yen Ying Lim, Kelly Nudelman, Laura Zahodne, Alden L Gross, Dan Mungas, Keith F Widaman, Julie Schneider

Journal article  |  2018  |  Annals of Neurology

OBJECTIVE: Our objectives were to characterize the inter-relation of known dementia-related neuropathologies in one comprehensive ..

O2-15-03: DIFFERENTIAL RISK FACTORS FOR PROGRESSION TO MCI/DEMENTIA BY AMYLOID-BETA STATUS

Christa Dang, Karra D Harrington, Yen Lim, Nawaf Yassi, Martha Hickey, David Ames, Christopher C Rowe, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Alzheimer's & Dementia

P1-006: EXAMINING THE RESILIENCE OF SUPERAGERS: RISK OF CLINICAL PROGRESSION AND Aβ-ASSOCIATED MEMORY DECLINE OVER 8 YEARS

Christa Dang, Yen Lim, Karra D Harrington, Nawaf Yassi, Martha Hickey, David Ames, Christopher C Rowe, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Alzheimer's & Dementia

Alzheimer's Disease: Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms. Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms.

CL Masters, B Gu, S Laws, YY Lim, B Roberts, VL Villemagne, K Beyreuther

Book Chapter  |  2018

Association of beta-Amyloid and Apolipoprotein E epsilon 4 With Memory Decline in Preclinical Alzheimer Disease

Yen Ying Lim, Pawel Kalinowski, Robert H Pietrzak, Simon M Laws, Samantha C Burnham, David Ames, Victor L Villemagne, Christopher J Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Christopher C Rowe, Colin L Masters, Paul T Maruff

Journal article  |  2018  |  JAMA Neurology

Amyloid burden and incident depressive symptoms in preclinical Alzheimer's disease

Stephanie Perin, Karra D Harrington, Yen Ying Lim, Kathryn Ellis, David Ames, Robert H Pietrzak, Adrian Schembri, Stephanie Rainey-Smith, Olivier Salvado, Simon M Laws, Ralph N Martins, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Journal of Affective Disorders

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study

Sophie E Holmes, Irina Esterlis, Carolyn M Mazure, Yen Ying Lim, David Ames, Stephanie Rainey-Smith, Chris Fowler, Kathryn Ellis, Ralph N Martins, Olivier Salvado, Vincent Dore, Victor L Villemagne, Christopher C Rowe, Simon M Laws, Colin L Masters, Robert H Pietrzak, Paul Maruff

Journal article  |  2018  |  International Journal of Geriatric Psychiatry

Episodic Memory and Learning Dysfunction Over an 18-Month Period in Preclinical and Prodromal Alzheimer's Disease

Jenalle E Baker, Yen Ying Lim, Judith Jaeger, David Ames, Nicola T Lautenschlager, Joanne Robertson, Robert H Pietrzak, Peter J Snyder, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Journal of Alzheimer's Disease

Relationship Between Amyloid-beta Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults

Christa Dang, Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M Laws, Nawaf Yassi, Martha Hickey, Stephanie Rainey-Smith, Joanne Robertson, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2018  |  Journal of Alzheimer's Disease

Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance

Y Stern, EM Arenaza-Urquijo, D Bartrés-Faz, S Belleville, M Cantilon, G Chetelat, M Ewers, N Franzmeier, G Kempermann, WS Kremen, O Okonkwo, N Scarmeas, A Soldan, C Udeh-Momoh, M Valenzuela, P Vemuri, E Vuoksimaa, EM Arenaza Urquiljo, D Bartrés-Faz, M Cantillon, et al.

Journal article  |  2018  |  Alzheimer's & Dementia

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Yen Ying Lim, Qiao-Xin Li, David Ames, Colin L Masters, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article  |  2018  |  Journal of Alzheimer's Disease

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF

Yen Ying Lim, Stephanie Rainey-Smith, Yoon Lim, Simon M Laws, Veer Gupta, Tenielle Porter, Pierrick Bourgeat, David Ames, Christopher Fowler, Olivier Salvado, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Xin Fu Zhou, Ralph N Martins, Paul Maruff

Journal article  |  2017  |  International Psychogeriatrics

APOE genotype and early beta-amyloid accumulation in older adults without dementia

Yen Ying Lim, Elizabeth C Mormino

Journal article  |  2017  |  Neurology

Cerebral quantitative susceptibility mapping predicts amyloid-beta-related cognitive decline

Scott Ayton, Amir Fazlollahi, Pierrick Bourgeat, Parnesh Raniga, Amanda Ng, Yen Ying Lim, Ibrahima Diouf, Shawna Farquharson, Jurgen Fripp, David Ames, James Doecke, Patricia Desmond, Roger Ordidge, Colin L Masters, Christopher C Rowe, Paul Maruff, Victor L Villemagne, Olivier Salvado, Ashley I Bush

Journal article  |  2017  |  Brain

Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI)

Pradeep J Nathan, Yen Ying Lim, Rosemary Abbott, Samantha Galluzzi, Moira Marizzoni, Claudio Babiloni, Diego Albani, David Bartres-Faz, Mira Didic, Lucia Farotti, Lucilla Parnetti, Nicola Salvadori, Bernhard W Mueller, Gianluigi Forloni, Nicola Girtler, Tilman Hensch, Jorge Jovicich, Annebet Leeuwis, Camillo Marra, Jose Luis Molinuevo, et al.

Journal article  |  2017  |  Neurobiology of Aging

Amyloid burden and incident depressive symptoms in cognitively normal older adults

Karra D Harrington, Emma Gould, Yen Ying Lim, David Ames, Robert H Pietrzak, Alan Rembach, Stephanie Rainey-Smith, Ralph N Martins, Olivier Salvado, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2017  |  International Journal of Geriatric Psychiatry

Using Robust Normative Data to Investigate the Neuropsychology of Cognitive Aging

Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Stephanie Rainey-Smith, Joanne Robertson, Olivier Salvado, Colin L Masters, Paul Maruff

Journal article  |  2017  |  Archives of Clinical Neuropsychology

Amyloid β-associated cognitive decline in the absence of clinical disease progression and systemic illness.

Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M Laws, Ralph N Martins, Stephanie Rainey-Smith, Joanne Robertson, Christopher C Rowe, Olivier Salvado, Vincent Doré, Victor L Villemagne, Peter J Snyder, Colin L Masters, Paul Maruff

Journal article  |  2017  |  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

INTRODUCTION: High levels of amyloid β (Aβ) are associated with cognitive decline in cognitively normal (CN) older adults. This st..

Effect of APOE Genotype on Amyloid Deposition, Brain Volume, and Memory in Cognitively Normal Older Individuals.

Yen Ying Lim, Robert Williamson, Simon M Laws, Victor L Villemagne, Pierrick Bourgeat, Christopher Fowler, Stephanie Rainey-Smith, Olivier Salvado, Ralph N Martins, Christopher C Rowe, Colin L Masters, Paul Maruff, undefined AIBL Research Group

Journal article  |  2017  |  Journal of Alzheimer's Disease

BACKGROUND: The association between the apolipoprotein E (APOE) ɛ4 allele and high risk of developing Alzheimer's disease (AD) dem..

Increased Carbohydrate Intake is Associated with Poorer Performance in Verbal Memory and Attention in an APOE Genotype-Dependent Manner

Samantha L Gardener, Stephanie R Rainey-Smith, Hamid R Sohrabi, Michael Weinborn, Giuseppe Verdile, WMAD Binosha Fernando, Yen Ying Lim, Karra Harrington, Samantha Burnham, Kevin Taddei, Colin L Masters, Stuart L Macaulay, Christopher C Rowe, David Ames, Paul Maruff, Ralph N Martins

Journal article  |  2017  |  Journal of Alzheimer's Disease

Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis.

Jenalle E Baker, Yen Ying Lim, Robert H Pietrzak, Jason Hassenstab, Peter J Snyder, Colin L Masters, Paul Maruff

Journal article  |  2017  |  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

INTRODUCTION: This meta-analysis aimed to characterize the nature and magnitude of amyloid (Aβ)-related cognitive impairment and d..

APOE epsilon 4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults

Simone Hollands, Yen Ying Lim, Simon M Laws, Victor L Villemagne, Robert H Pietrzak, Karra Harrington, Tenielle Porter, Peter Snyder, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2017  |  Journal of Alzheimer's Disease

Plasma Cortisol, Brain Amyloid-beta, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study

Robert H Pietrzak, Simon M Laws, Yen Ying Lim, Sophie J Bender, Tenielle Porter, James Doecke, David Ames, Christopher Fowler, Colin L Masters, Lidija Milicic, Stephanie Rainey-Smith, Victor L Villemagne, Christopher C Rowe, Ralph N Martins, Paul Maruff

Journal article  |  2017  |  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

BACKGROUND: Hypothalamic-pituitary-adrenal axis dysregulation, which is typically assessed by measuring cortisol levels, is associ..

beta-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men

Sophie E Holmes, Irina Esterlis, Carolyn M Mazure, Yen Ying Lim, David Ames, Stephanie Rainey-Smith, Ralph N Martins, Olivier Salvado, Vincent Dore, Victor L Villemagne, Christopher C Rowe, Simon M Laws, Colin L Masters, Paul Maruff, Robert H Pietrzak

Journal article  |  2016  |  The American Journal of Geriatric Psychiatry

Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia

Yen Ying Lim, Victor L Villemagne, Simon M Laws, Robert H Pietrzak, David Ames, Christopher Fowler, Stephanie Rainey-Smith, Peter J Snyder, Pierrick Bourgeat, Ralph N Martins, Olivier Salvado, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2016  |  Journal of Molecular Neuroscience

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

Yen Ying Lim, Jason Hassenstab, Carlos Cruchaga, Alison Goate, Anne M Fagan, Tammie LS Benzinger, Paul Maruff, Peter J Snyder, Colin L Masters, Ricardo Allegri, Jasmeer Chhatwal, Martin R Farlow, Neill R Graff-Radford, Christoph Laske, Johannes Levin, Eric McDade, John M Ringman, Martin Rossor, Stephen Salloway, Peter R Schofield, et al.

Journal article  |  2016  |  Brain

A-related memory decline in APOE epsilon 4 noncarriers: Implications for Alzheimer disease

Yen Ying Lim, Simon M Laws, Victor L Villemagne, Robert H Pietrzak, Tenielle Porter, David Ames, Christopher Fowler, Stephanie Rainey-Smith, Peter J Snyder, Ralph N Martins, Olivier Salvado, Pierrick Bourgeat, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2016  |  Neurology

Disclosure of positron emission tomography amyloid imaging results: A preliminary study of safety and tolerability

Yen Ying Lim, Paul Maruff, Christine Getter, Peter J Snyder

Journal article  |  2016  |  Alzheimer's & Dementia

Resting-State Cardiac Workload is Related to Both Increased Neocortical Aggregation of Amyloid-beta and Relative Impairments in Spatial Working Memory in Pre-Clinical Alzheimer's Disease

Claudia Yang Santos, Yen Ying Lim, Wen-Chih Wu, Jason Timothy Machan, Shahena Polynice, Rachel Schindler, Paul Maruff, Peter Jeffrey Snyder

Journal article  |  2016  |  Journal of Alzheimer's Disease

Nonvascular retinal imaging markers of preclinical Alzheimer's disease.

Peter J Snyder, Lenworth N Johnson, Yen Ying Lim, Cláudia Y Santos, Jessica Alber, Paul Maruff, Brian Fernández

Journal article  |  2016  |  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

INTRODUCTION: In patients with Alzheimer's disease (AD) and mild cognitive impairment, structural changes in the retina (i.e., red..

Sensitivity of composite scores to amyloid burden in preclinical Alzheimer's disease: Introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score.

Yen Ying Lim, Peter J Snyder, Robert H Pietrzak, Albulene Ukiqi, Victor L Villemagne, David Ames, Olivier Salvado, Pierrick Bourgeat, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

Journal article  |  2016  |  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

INTRODUCTION: Cognitive composite scores developed for preclinical Alzheimer's disease (AD) often consist of multiple cognitive do..

APOE and BDNF polymorphisms moderate amyloid beta-related cognitive decline in preclinical Alzheimer's disease

YY Lim, VL Villemagne, SM Laws, RH Pietrzak, PJ Snyder, D Ames, KA Ellis, K Harrington, A Rembach, RN Martins, CC Rowe, CL Masters, P Maruff

Journal article  |  2015  |  Molecular Psychiatry

Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE epsilon 4 and Is Detectable over 18-Months

Christine Thai, Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Kathryn A Ellis, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  PLOS ONE

APOE epsilon 4 moderates amyloid-related memory decline in preclinical Alzheimer's disease

Yen Ying Lim, Victor L Villemagne, Robert H Pietrzak, David Ames, Kathryn A Ellis, Karra Harrington, Peter J Snyder, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  Neurobiology of Aging

Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing

Robert H Pietrzak, Yen Ying Lim, David Ames, Karra Harrington, Carolina Restrepo, Ralph N Martins, Alan Rembach, Simon M Laws, Colin L Masters, Victor L Villemagne, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  Neurobiology of Aging

Amyloid-beta, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease A Multicenter, Prospective Cohort Study

Robert H Pietrzak, Yen Ying Lim, Alexander Neumeister, David Ames, Kathryn A Ellis, Karra Harrington, Nicola T Lautenschlager, Carolina Restrepo, Ralph N Martins, Colin L Masters, Victor L Villemagne, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  JAMA Psychiatry

Relationships Between Performance on the Cogstate Brief Battery, Neurodegeneration, and A beta Accumulation in Cognitively Normal Older Adults and Adults with MCI

Yen Ying Lim, Robert H Pietrzak, Pierrick Bourgeat, David Ames, Kathryn A Ellis, Alan Rembach, Karra Harrington, Olivier Salvado, Ralph N Martins, Peter J Snyder, Colin L Masters, Christopher C Rowe, Victor L Villemagne, Paul Maruff

Journal article  |  2015  |  Archives of Clinical Neuropsychology

Dietary patterns and cognitive decline in an Australian study of ageing

SL Gardener, SR Rainey-Smith, MB Barnes, HR Sohrabi, M Weinborn, YY Lim, K Harrington, K Taddei, Y Gu, A Rembach, C Szoeke, KA Ellis, CL Masters, SL Macaulay, CC Rowe, D Ames, JB Keogh, N Scarmeas, RN Martins

Journal article  |  2015  |  Molecular Psychiatry

Amyloid-beta and depression in healthy older adults: A systematic review

Karra D Harrington, Yen Ying Lim, Emma Gould, Paul Maruff

Journal article  |  2015  |  Australian & New Zealand Journal of Psychiatry

Amyloid-beta Related Memory Decline is not Associated with Subjective or Informant Rated Cognitive Impairment in Healthy Adults

Simone Hollands, Yen Ying Lim, Rachel Buckley, Robert H Pietrzak, Peter J Snyder, David Ames, Kathryn A Ellis, Karra Harrington, Nicola Lautenschlager, Ralph N Martins, Colin L Masters, Victor L Villemagne, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  Journal of Affective Disorders

A beta and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease

Yen Ying Lim, Paul Maruff, Robert H Pietrzak, Kathryn A Ellis, David Darby, David Ames, Karra Harrington, Ralph N Martins, Colin L Masters, Cassandra Szoeke, Greg Savage, Victor L Villemagne, Christopher C Rowe

Journal article  |  2014  |  Alzheimers Dement

Anxiety symptoms, cerebral amyloid burden and memory decline in healthy older adults without dementia: 3-year prospective cohort study

Robert H Pietrzak, J Cobb Scott, Alexander Neumeister, Yen Ying Lim, David Ames, Kathryn A Ellis, Karra Harrington, Nicola T Lautenschlager, Cassandra Szoeke, Ralph N Martins, Colin L Masters, Victor L Villemagne, Christopher C Rowe, Paul Maruff

Journal article  |  2014  |  British Journal of Psychiatry

Effect of BDNF Val66Met on Memory Decline and Hippocampal Atrophy in Prodromal Alzheimer's Disease: A Preliminary Study

Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Robert H Pietrzak, Kathryn A Ellis, Karra Harrington, Pierrick Bourgeat, Ashley I Bush, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

Journal article  |  2014  |  PLoS One

Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease

Yen Ying Lim, Paul Maruff, Robert H Pietrzak, David Ames, Kathryn A Ellis, Karra Harrington, Nicola T Lautenschlager, Cassandra Szoeke, Ralph N Martins, Colin L Masters, Victor L Villemagne, Christopher C Rowe

Journal article  |  2014  |  Brain

The association of A beta amyloid and composite cognitive measures in healthy older adults and MCI

Karra D Harrington, Yen Ying Lim, Kathryn A Ellis, Carly Copolov, David Darby, Michael Weinborn, David Ames, Ralph N Martins, Greg Savage, Cassandra Szoeke, Christopher Rowe, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2013  |  International Psychogeriatrics

Cognitive Decline in Adults with Amnestic Mild Cognitive Impairment and High Amyloid-beta: Prodromal Alzheimer's Disease?

Yen Ying Lim, Kathryn A Ellis, Karra Harrington, Robert H Pietrzak, Joanne Gale, David Ames, Ashley I Bush, David Darby, Ralph N Martins, Colin L Masters, Christopher C Rowe, Greg Savage, Cassandra Szoeke, Victor L Villemagne, Paul Maruff

Journal article  |  2013  |  Journal of Alzheimer's Disease

Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease.

Paul Maruff, Yen Ying Lim, David Darby, Kathryn A Ellis, Robert H Pietrzak, Peter J Snyder, Ashley I Bush, Cassandra Szoeke, Adrian Schembri, David Ames, Colin L Masters, undefined AIBL Research Group

Journal article  |  2013  |  BMC Psychology

BACKGROUND: Previous studies have demonstrated the utility and sensitivity of the CogState Brief Battery (CBB) in detecting cognit..