Yen Ying Lim

Association of β-amyloid level, clinical progression and longitudinal cognitive change in normal older individuals.

Laura M van der Kall, Thanh Truong, Samantha C Burnham, Vincent Doré, Rachel S Mulligan, Svetlana Bozinovski, Fiona Lamb, Pierrick Bourgeat, Jurgen Fripp, Stephanie Schultz, Yen Y Lim, Simon M Laws, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Paul Maruff, Colin L Masters, et al.

Journal article  |  2020  |  Neurology

OBJECTIVE: To determine the effect of Aβ level on progression risk to MCI or dementia and longitudinal cognitive change in cogniti..

Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance.

Yaakov Stern, Eider M Arenaza-Urquijo, David Bartrés-Faz, Sylvie Belleville, Marc Cantilon, Gael Chetelat, Michael Ewers, Nicolai Franzmeier, Gerd Kempermann, William S Kremen, Ozioma Okonkwo, Nikolaos Scarmeas, Anja Soldan, Chinedu Udeh-Momoh, Michael Valenzuela, Prashanthi Vemuri, Eero Vuoksimaa, undefined the Reserve, Resilience and Protective Factors PIA Empirical Definitions and Conceptual Frameworks Workgroup

Journal article  |  2020  |  Alzheimer's & Dementia

Several concepts, which in the aggregate get might be used to account for "resilience" against age- and disease-related changes, h..

Unsupervised assessment of cognition in the Healthy Brain Project: Implications for web-based registries of individuals at risk for Alzheimer's disease.

Stephanie Perin, Rachel F Buckley, Matthew P Pase, Nawaf Yassi, Alexandra Lavale, Peter H Wilson, Adrian Schembri, Paul Maruff, Yen Ying Lim

Journal article  |  2020  |  Alzheimer's and Dementia: Translational Research and Clinical Interventions

Introduction: Web-based platforms are used increasingly to assess cognitive function in unsupervised settings. The utility of cogn..

Influence of Comorbidity of Cerebrovascular Disease and Amyloid-beta on Alzheimer's Disease

Nawaf Yassi, Saima Hilal, Ying Xia, Yen Ying Lim, Rosie Watson, Hugo Kuijf, Christopher Fowler, Paul Yates, Paul Maruff, Ralph Martins, David Ames, Christopher Chen, Christopher C Rowe, Victor L Villemagne, Olivier Salvado, Patricia M Desmond, Colin L Masters

Journal article  |  2020  |  Journal of Alzheimer's Disease

BACKGROUND: Quantifying the contribution of cerebrovascular disease to the clinical and pathological profile of Alzheimer's diseas..

Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance.

Christa Dang, Nawaf Yassi, Karra D Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R Sohrabi, James D Doecke, Jurgen Fripp, Olivier Salvado, Peter J Snyder, Michael Weinborn, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, undefined AIBL Research Group

Journal article  |  2019  |  Alzheimer's & dementia (Amsterdam, Netherlands)

Introduction: Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration..

Visual Paired Associate Learning Deficits Associated With Elevated Beta-Amyloid in Cognitively Normal Older Adults

Jenalle E Baker, Robert H Pietrzak, Simon M Laws, David Ames, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, Yen Ying Lim

Journal article  |  2019  |  Neuropsychology

OBJECTIVE: Previous studies have shown that paired associate learning (PAL), a type of episodic memory, is impaired in early Alzhe..

Use of an experimental language acquisition paradigm for standardized neuropsychological assessment of learning: A pilot study in young and older adults

Jenalle E Baker, Loren Bruns, Jason Hassenstab, Colin L Masters, Paul Maruff, Yen Ying Lim

Journal article  |  2019  |  Journal of Clinical and Experimental Neuropsychology

Determining clinically meaningful decline in preclinical Alzheimer disease

Philip S Insel, Michael Weiner, R Scott Mackin, Elizabeth Mormino, Yen Ying Lim, Erik Stomrud, Sebastian Palmqvist, Colin L Masters, Paul T Maruff, Oskar Hansson, Niklas Mattsson

Journal article  |  2019  |  Neurology

OBJECTIVE: To determine the time required for a preclinical Alzheimer disease population to decline in a meaningful way, use estim..

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid beta-Associated Cognitive Decline in Older Adults

Christa Dang, Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M Laws, Nawaf Yassi, Martha Hickey, Stephanie R Rainey-Smith, Joanne Robertson, Christopher C Rowe, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article  |  2019  |  Archives of Clinical Neuropsychology

Objective: To prospectively examine 8-year risk of clinical disease progression to mild cognitive impairment (MCI)/dementia in old..

COMT val158met is not associated with Aβ-amyloid and APOE ε4 related cognitive decline in cognitively normal older adults.

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Hamid R Sohrabi, Madeline Peretti, Yen Ying Lim, Michael Weinborn, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article  |  2019  |  IBRO Reports

The non-synonymous single nucleotide polymorphism (SNP), Val158Met within the Catechol-O-methyltransferase (COMT) gene has been as..