Prudence Pereira-Fantini

Respiratory strategy at birth initiates distinct lung injury phenotypes in the preterm lamb lung.

Prue M Pereira-Fantini, Kristin Ferguson, Karen McCall, Regina Oakley, Elizabeth Perkins, Sean Byars, Nicholas Williamson, Shuai Nie, David G Tingay

Journal article  |  2022  |  Respiratory Research

BACKGROUND: A lack of clear trial evidence often hampers clinical decision-making during support of the preterm lung at birth. Pro..

Dynamic positive end-expiratory pressure strategies using time and pressure recruitment at birth reduce early expression of lung injury in preterm lambs

David G Tingay, Prue M Pereira-Fantini, Martijn Miedema, Karen E McCall, Elizabeth J Perkins, Georgie Dowse, Nicholas Schinckel, Magdy Sourial, Peter G Davis

Journal article  |  2022  |  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Positive end-expiratory pressure (PEEP) is critical to the preterm lung at birth, but the optimal PEEP level remains uncertain. Th..

Quantitative lung ultrasound detects dynamic changes in lung recruitment in the preterm lamb

Arun Sett, Gillian WC Foo, Kelly R Kenna, Rebecca J Sutton, Elizabeth J Perkins, Magdy Sourial, Sheryle R Rogerson, Brett J Manley, Peter G Davis, Prue M Pereira-Fantini, David G Tingay

Journal article  |  2022  |  PEDIATRIC RESEARCH

BACKGROUND: Lung ultrasound (LUS) may not detect small, dynamic changes in lung volume. Mean greyscale measurement using computer-..

Aeration strategy at birth does not impact carotid haemodynamics in preterm lambs.

Sophia I Dahm, Kelly R Kenna, David Stewart, Prue M Pereira-Fantini, Karen E McCall, Elizabeth J Perkins, Magdy Sourial, David G Tingay

Journal article  |  2022  |  Pediatr Res

BACKGROUND: The impact of different respiratory strategies at birth on the preterm lung is well understood; however, concerns have..

Lung ultrasound of the dependent lung detects real-time changes in lung volume in the preterm lamb

Arun Sett, Kelly R Kenna, Rebecca J Sutton, Elizabeth J Perkins, Magdy Sourial, Jack D Chapman, Susan M Donath, Arun Sasi, Sheryle R Rogerson, Brett J Manley, Peter G Davis, Prue M Pereira-Fantini, David G Tingay

Journal article  |  2022  |  ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION

BACKGROUND: Effective lung protective ventilation requires reliable, real-time estimation of lung volume at the bedside. Neonatal ..

Imaging the Respiratory Transition at Birth Unraveling the Complexities of the First Breaths of Life

David G Tingay, Olivia Farrell, Jessica Thomson, Elizabeth J Perkins, Prue M Pereira-Fantini, Andreas D Waldmann, Christoph Ruegger, Andy Adler, Peter G Davis, Inez Frerichs

Journal article  |  2021  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rationale: The transition to air breathing at birth is a seminal respiratory event common to all humans, but the intrathoracic pro..

Regional ventilation characteristics during non-invasive respiratory support in preterm infants

Jessica Thomson, Christoph M Ruegger, Elizabeth J Perkins, Prue M Pereira-Fantini, Olivia Farrell, Louise S Owen, David G Tingay

Journal article  |  2021  |  ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION

OBJECTIVES: To determine the regional ventilation characteristics during non-invasive ventilation (NIV) in stable preterm infants...

Synchronized Inflations Generate Greater Gravity-Dependent Lung Ventilation in Neonates

Georgie Dowse, Elizabeth Perkins, Jessica Thomson, Nicholas Schinckel, Prue Pereira-Fantini, David Tingay

Journal article  |  2021  |  JOURNAL OF PEDIATRICS

OBJECTIVE: To describe the regional distribution patterns of tidal ventilation within the lung during mechanical ventilation that ..

Skin-to-skin care alters regional ventilation in stable neonates

Nicholas F Schinckel, Leah Hickey, Elizabeth J Perkins, Prue M Pereira-Fantini, Sienna Koeppenkastrop, Isabella Stafford, Georgie Dowse, David G Tingay

Journal article  |  2021  |  ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION

OBJECTIVE: Skin-to-skin care (SSC) has proven psychological benefits; however, the physiological effects are less clearly defined...

Proteomics reveals region-specific hemostatic alterations in response to mechanical ventilation in a preterm lamb model of lung injury

Christine Schmid, Vera Ignjatovic, Boyuan Pang, Shuai Nie, Nicholas A Williamson, David G Tingay, Prue M Pereira-Fantini

Journal article  |  2020  |  Thrombosis Research

Introduction Preterm infants often require assisted ventilation, however ventilation when applied to the immature lung can initiat..