Shu Mei Teo

The gut microbiome is a significant risk factor for future chronic lung disease.

Yang Liu, Shu Mei Teo, Guillaume Méric, Howard HF Tang, Qiyun Zhu, Jon G Sanders, Yoshiki Vázquez-Baeza, Karin Verspoor, Ville A Vartiainen, Pekka Jousilahti, Leo Lahti, Teemu Niiranen, Aki S Havulinna, Rob Knight, Veikko Salomaa, Michael Inouye

Journal article  |  2022  |  J Allergy Clin Immunol

BACKGROUND: The gut-lung axis is generally recognized, but there are few large studies of the gut microbiome and incident respirat..

Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

Yang Liu, Guillaume Meric, Aki S Havulinna, Shu Mei Teo, Fredrik Aberg, Matti Ruuskanen, Jon Sanders, Qiyun Zhu, Anupriya Tripathi, Karin Verspoor, Susan Cheng, Mohit Jain, Pekka Jousilahti, Yoshiki Vazquez-Baeza, Rohit Loomba, Leo Lahti, Teemu Niiranen, Veikko Salomaa, Rob Knight, Michael Inouye

Journal article  |  2022  |  CELL METABOLISM

The gut microbiome has shown promise as a predictive biomarker for various diseases. However, the potential of gut microbiota for ..

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

Scott C Ritchie, Samuel A Lambert, Matthew Arnold, Shu Mei Teo, Sol Lim, Petar Scepanovic, Jonathan Marten, Sohail Zahid, Mark Chaffin, Yingying Liu, Gad Abraham, Willem H Ouwehand, David J Roberts, Nicholas A Watkins, Brian G Drew, Anna C Calkin, Emanuele Di Angelantonio, Nicole Soranzo, Stephen Burgess, Michael Chapman, et al.

Journal article  |  2021  |  NATURE METABOLISM

Cardiometabolic diseases are frequently polygenic in architecture, comprising a large number of risk alleles with small effects sp..

Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk

Howard HF Tang, Anna Lang, Shu Mei Teo, Louise M Judd, Ronald Gangnon, Michael D Evans, Kristine E Lee, Rose Vrtis, Patrick G Holt, Robert F Lemanske, Daniel J Jackson, Kathryn E Holt, Michael Inouye, James E Gern

Journal article  |  2021  |  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

BACKGROUND: Studies indicate that the nasal microbiome may correlate strongly with the presence or future risk of childhood asthma..

The intersect of genetics, environment, and microbiota in asthma-perspectives and challenges

Howard HF Tang, Shu Mei Teo, Peter D Sly, Patrick G Holt, Michael Inouye

Journal article  |  2021  |  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In asthma, a significant portion of the interaction between genetics and environment occurs through microbiota. The proposed mecha..

Luminal microbiota related to Crohn's disease recurrence after surgery

Amy L Hamilton, Michael A Kamm, Peter De Cruz, Emily K Wright, Hai Feng, Josef Wagner, Joseph JY Sung, Carl D Kirkwood, Michael Inouye, Shu-Mei Teo

Journal article  |  2020  |  GUT MICROBES

BACKGROUND: Microbial factors are likely to be involved in the recurrence of Crohn's disease (CD) after bowel resection. We invest..

Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk

Qin Qin Huang, Howard HF Tang, Shu Mei Teo, Danny Mok, Scott C Ritchie, Artika P Nath, Marta Brozynska, Agus Salim, Andrew Bakshi, Barbara J Holt, Chiea Chuen Khor, Peter D Sly, Patrick G Holt, Kathryn E Holt, Michael Inouye

Journal article  |  2020  |  NATURE COMMUNICATIONS

Chronic immune-mediated diseases of adulthood often originate in early childhood. To investigate genetic associations between neon..

Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy

Artika P Nath, Scott C Ritchie, Nastasiya F Grinberg, Howard Ho-Fung Tang, Qin Qin Huang, Shu Mei Teo, Ari V Ahola-Olli, Peter Wurtz, Aki S Havulinna, Kristiina Santalahti, Niina Pitkanen, Terho Lehtimaki, Mika Kahonen, Leo-Pekka Lyytikainen, Emma Raitoharju, Ilkka Seppala, Antti-Pekka Sarin, Samuli Ripatti, Aarno Palotie, Markus Perola, et al.

Journal article  |  2019  |  AMERICAN JOURNAL OF HUMAN GENETICS

Cytokines are essential regulatory components of the immune system, and their aberrant levels have been linked to many disease sta..

P3431Machine learning applied to energy waveform ECG for prediction of subclinical myocardial dysfunction

E Potter, Y Liu, S Teo, M Inouye, TH Marwick

Journal article  |  2019  |  European Heart Journal

Abstract Background Energy waveform (ew) ECG used continuous wavelet transform..

Trajectories of childhood immune development and respiratory health relevant to asthma and allergy

Howard HF Tang, Shu Mei Teo, Danielle CM Belgrave, Michael D Evans, Daniel J Jackson, Marta Brozynska, Merci MH Kusel, Sebastian L Johnston, James E Gern, Robert F Lemanske, Angela Simpson, Adnan Custovic, Peter D Sly, Patrick G Holt, Kathryn E Holt, Michael Inouye

Journal article  |  2018  |  ELIFE