Daniel Steinfort

Heterogeneity of tumour mutational burden in metastatic NSCLC demonstrated by endobronchial ultrasound sampling

Tracy L Leong, Christian Aloe, Savreet Aujla, Hao Wang, Velimir Gayevskiy, Marie-Liesse Asselin-Labat, Lesley-Ann Gray, Daniel Steinfort, Steven Bozinovski

Journal article  |  2023  |  Frontiers in Oncology

IntroductionTumour mutational burden (TMB) is an important emerging biomarker for immune checkpoint inhibitors (ICI). The stabilit..

Safety and Feasibility of a Novel Externally Cooled Bronchoscopic Radiofrequency Ablation Catheter for Ablation of Peripheral Lung Tumours: A First-In-Human Dose Escalation Study

Daniel PP Steinfort, Phillip Antippa, Kanishka Rangamuwa, Louis BB Irving, Michael Christie, Ewan Chan, Brett Marinelli, Jie Wang, Ken YY Yoneda, Shashank Raina, Felix JJ Herth

Journal article  |  2023  |  RESPIRATION

BACKGROUND: Radiofrequency ablation (RFA) is an established modality for percutaneous ablation of non-small cell lung cancer (NSCL..

ImmunoPET: IMaging of cancer imMUNOtherapy targets with positron Emission Tomography: a phase 0/1 study characterising PD-L1 with 89Zr-durvalumab (MEDI4736) PET/CT in stage III NSCLC patients receiving chemoradiation study protocol.

Fiona Hegi-Johnson, Stacey E Rudd, Christian Wichmann, Tim Akhurst, Peter Roselt, Jenny Trinh, Thomas John, Lisa Devereux, Paul S Donnelly, Rod Hicks, Andrew M Scott, Daniel Steinfort, Stephen Fox, Benjamin Blyth, Sagun Parakh, Gerard G Hanna, Jason Callahan, Kate Burbury, Michael MacManus

Journal article  |  2022  |  BMJ Open

BACKGROUND: ImmunoPET is a multicentre, single arm, phase 0-1 study that aims to establish if 89Zr-durvalumab PET/CT can be used t..

Systematic endoscopic staging of mediastinum to determine impact on radiotherapy for locally advanced lung cancer (SEISMIC): protocol for a prospective single arm multicentre interventional study

Daniel P Steinfort, Shankar Siva, Kanishka Rangamuwa, Percy Lee, David Fielding, Phan Nguyen, Barton R Jennings, Shaun Yo, Nick Hardcastle, Gargi Kothari, Laurence Crombag, Jouke Annema, Kazuhiro Yasufuku, David E Ost, Louis B Irving

Journal article  |  2022  |  BMC PULMONARY MEDICINE

BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is established as the preferred method of..

Safety and feasibility of a novel externally cooled bronchoscopic radiofrequency ablation catheter for ablation of peripheral lung tumours: a first-in-human dose escalation study

D Steinfort, P Antippa, K Rangamuwa, L Irving, M Christie, E Chan, D Tanaka, K Yoneda, J Christie, F Herth, S Raina

Conference Proceedings  |  2022  |  11.01 - Lung cancer

Another line of defence

Daniel P Steinfort, Douglas F Johnson

Journal article  |  2022  |  RESPIROLOGY

See related article.

Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels.

P Ramarao-Milne, O Kondrashova, A-M Patch, K Nones, LT Koufariotis, F Newell, V Addala, V Lakis, O Holmes, C Leonard, S Wood, Q Xu, P Mukhopadhyay, MM Naeini, D Steinfort, JP Williamson, M Bint, C Pahoff, PT Nguyen, S Twaddell, et al.

Journal article  |  2022  |  ESMO Open

BACKGROUND: Next-generation sequencing is used in cancer research to identify somatic and germline mutations, which can predict se..

Programmed Death-Ligand 1 Copy Number Loss in NSCLC Associates With Reduced Programmed Death-Ligand 1 Tumor Staining and a Cold Immunophenotype

Savreet Aujla, Christian Aloe, Amanda Vannitamby, Shona Hendry, Kanishka Rangamuwa, Hao Wang, Ross Vlahos, Stavros Selemidis, Tracy Leong, Daniel Steinfort, Steven Bozinovski

Journal article  |  2022  |  JOURNAL OF THORACIC ONCOLOGY

INTRODUCTION: Programmed death-ligand 1 (PD-L1) copy number gains may be predictive of clinical response to immunotherapy in NSCLC..

USPSTF2013 versus PLCOm2012 lung cancer screening eligibility criteria (International Lung Screening Trial): interim analysis of a prospective cohort study

Martin C Tammemagi, Mamta Ruparel, Alain Tremblay, Renelle Myers, John Mayo, John Yee, Sukhinder Atkar-Khattra, Ren Yuan, Sonya Cressman, John English, Eric Bedard, Paul MacEachern, Paul Burrowes, Samantha L Quaife, Henry Marshall, Ian Yang, Rayleen Bowman, Linda Passmore, Annette McWilliams, Fraser Brims, et al.

Journal article  |  2022  |  LANCET ONCOLOGY

BACKGROUND: Lung cancer is a major health problem. CT lung screening can reduce lung cancer mortality through early diagnosis by a..

Teaching Radial Endobronchial Ultrasound with a Three-Dimensional-printed Radial Ultrasound Model

Anna Ridgers, Jasun Li, Jasamine Coles-Black, Michael Jiang, Gordon Chen, Jason Chuen, Christine F McDonald, Graham Hepworth, Daniel P Steinfort, Louis B Irving, Peter Wallbridge, Barton R Jennings, Nguyen Phan, Tracy L Leong

Journal article  |  2021  |  ATS SCHOLAR

BACKGROUND: Peripheral pulmonary lesion (PPL) incidence is rising because of increased chest imaging sensitivity and frequency. Fo..