David Edgar

Reduced live birth rates in frozen versus fresh single cleavage embryo transfer cycles: A cross -sectional study

Wan Tinn Teh, Alex Polyakov, Claire Garrett, David Edgar, John Mcbain, Peter Adrian Walton Rogers

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE

Background: Studies have suggested that embryo-endometrial developmental asynchrony caused by slow-growing embryos can be correcte..

Cryopreservation of female reproductive potential

Debra A Gook, David H Edgar

Journal article  |  2019  |  BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Storing female reproductive potential can offer enhanced prospects for future conception in women whose fertility is threatened by..

Slow Freezing and Thawing of Human Cleavage Stage Embryos

David H Edgar, Janell Archer, Debra A Gook

Journal article  |  2017  |  CRYOPRESERVATION OF MAMMALIAN GAMETES AND EMBRYOS: METHODS AND PROTOCOLS

The ability to store human embryos in a viable state at very low temperatures has been critical to the evolution of responsible pr..

Closed vitrification of human oocytes and blastocysts: outcomes from a series of clinical cases

Debra A Gook, Boon Choo, Harold Bourne, Kelly Lewis, David H Edgar

Journal article  |  2016  |  JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

PURPOSE: High survival rates and clinical outcomes similar to those from fresh oocytes and blastocysts have been observed with ope..

Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study

Z Li, YA Wang, W Ledger, DH Edgar, EA Sullivan

Journal article  |  2014  |  HUMAN REPRODUCTION

STUDY QUESTION: What are the clinical efficacy and perinatal outcomes following transfer of vitrified blastocysts compared with tr..

Impact of oxygen concentration on adult murine pre-antral follicle development in vitro and the corresponding metabolic profile

Debra A Gook, DH Edgar, K Lewis, JR Sheedy, DK Gardner

Journal article  |  2014  |  MOLECULAR HUMAN REPRODUCTION

Oxygen concentration during in vitro culture has a significant effect on the physiology of embryos, altering metabolic profile and..

A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos

David H Edgar, Debra A Gook

Journal article  |  2012  |  HUMAN REPRODUCTION UPDATE

BACKGROUND: Vitrification is now a commonly applied technique for cryopreservation in assisted reproductive technology (ART) repla..

The Alpha consensus meeting on cryopreservation key performance indicators and benchmarks: proceedings of an expert meeting

Basak Balaban, Veronica Bianchi, Virginia Bolton, Ana Cobo, Thomas Ebner, David Edgar, Martin Greuner, Stanley Leibo, David Mortimer, Zsolt Peter Nagy, Lodovico Parmegiani, Tammie Roy, Alan Thornhill, Lisbet Van Landuyt, Pierre Vanderzwalmen, Matthew Tex VerMilyea, Maureen Wood

Journal article  |  2012  |  REPRODUCTIVE BIOMEDICINE ONLINE

This proceedings report presents the outcomes from an international workshop designed to establish consensus on: definitions for k..

Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group

Debra A Gook, David H Edgar

Journal article  |  2011  |  JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Previous reports of slow cooling of human mature oocytes have shown a reduced clinical efficiency relative to fresh oocytes. This ..

The first Australian experience of heterotopic grafting of cryopreserved ovarian tissue: evidence of establishment of normal ovarian function

Catharyn J Stern, Manuela G Toledo, Lyndon G Hale, Debra A Gook, David H Edgar

Journal article  |  2011  |  AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

Cryostorage of reproductive potential, in the form of ovarian cortex, for young women about to undergo cytotoxic therapies has bee..