Matthew Ritchie

High-LET Radiation Increases Tumor Progression in a K-Ras-Driven Model of Lung Adenocarcinoma

Marie-Liesse Asselin-Labat, Rishi Rampersad, Xia Xu, Matthew E Ritchie, Jacob Michalski, Lingling Huang, Mark W Onaitis

Journal article  |  2017  |  RADIATION RESEARCH

High-linear energy transfer (LET) radiation encountered by astronauts in space generates clustered DNA damage that is potentially ..

Combining multiple tools outperforms individual methods in gene set enrichment analyses

Monther Alhamdoosh, Milica Ng, Nicholas J Wilson, Julie M Sheridan, Huy Huynh, Michael J Wilson, Matthew E Ritchie

Journal article  |  2017  |  BIOINFORMATICS

MOTIVATION: Gene set enrichment (GSE) analysis allows researchers to efficiently extract biological insight from long lists of dif..

Easy and efficient ensemble gene set testing with EGSEA.

Monther Alhamdoosh, Charity W Law, Luyi Tian, Julie M Sheridan, Milica Ng, Matthew E Ritchie

Journal article  |  2017  |  F1000Res

Gene set enrichment analysis is a popular approach for prioritising the biological processes perturbed in genomic datasets. The Bi..

Deciphering the Innate Lymphoid Cell Transcriptional Program

Cyril Seillet, Lisa A Mielke, Daniela B Amann-Zalcenstein, Shian Su, Jerry Gao, Francisca F Almeida, Wei Shi, Matthew E Ritchie, Shalin H Naik, Nicholas D Huntington, Sebastian Carotta, Gabrielle T Belz

Journal article  |  2016  |  CELL REPORTS

Innate lymphoid cells (ILCs) are enriched at mucosal surfaces, where they provide immune surveillance. All ILC subsets develop fro..