Pamela Leong

Differential network analysis of oral microbiome metatranscriptomes identifies community scale metabolic restructuring in dental caries.

Josh L Espinoza, Manolito Torralba, Pamela Leong, Richard Saffery, Michelle Bockmann, Claire Kuelbs, Suren Singh, Toby Hughes, Jeffrey M Craig, Karen E Nelson, Chris L Dupont

Journal article  |  2022  |  PNAS Nexus

Dental caries is a microbial disease and the most common chronic health condition, affecting nearly 3.5 billion people worldwide. ..

Investigating the impact of oral health on pregnancy and offspring outcomes: protocol for the Lifetime Impact of ORal heAlth (LIORA) cohort study

Mei-Ling Zhao, Feng-Jing Zhang, Wen-Rong Jiang, Yinyin Xia, Chang Chen, Ting Zhang, Ting-Li Han, Xin-Yang Yu, Peter Mei, Hong-Mei Zhang, Xin Jin, Boris Novakovic, Pamela Leong, Murray Thompson, Richard Saffery, Richard D Cannon, Hua Zhang, Ping Ji

Journal article  |  2022  |  BMJ OPEN

INTRODUCTION: Oral health is a fundamental component of well-being, and is closely associated with overall health and quality of l..

Cohort Profile: The Chongqing Longitudinal Twin Study (LoTiS)

Chao Tong, Li Wen, Lan Wang, Xin Fan, Yan Zhao, Yamin Liu, Xing Wang, Shuai Huang, Junnan Li, Jie Li, Longqiong Wang, Jie Gan, Lian Yu, Lianlian Wang, Huisheng Ge, Chengjin He, Jiaxiao Yu, Tianjiao Liu, Xiyao Liu, Yang Yang, et al.

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Perinatal outcomes and offspring growth profiles in twin pregnancies complicated by gestational diabetes mellitus: A longitudinal cohort study

Youwen Mei, Jiaxiao Yu, Li Wen, Xin Fan, Yan Zhao, Jie Li, Juan Qiao, Huijia Fu, Pamela Leong, Richard Saffery, Qi Tong, Mark D Kilby, Hongbo Qi, Chao Tong, Philip N Baker

Journal article  |  2021  |  DIABETES RESEARCH AND CLINICAL PRACTICE

AIMS: To evaluate the influence of gestational diabetes mellitus (GDM) on the perinatal outcomes of twin pregnancies and its impac..

Longitudinal Study of Oral Microbiome Variation in Twins

Marcelo Freire, Ahmed Moustafa, Derek M Harkins, Manolito G Torralba, Yun Zhang, Pamela Leong, Richard Saffery, Michelle Bockmann, Claire Kuelbs, Toby Hughes, Jeffrey M Craig, Karen E Nelson

Journal article  |  2020  |  SCIENTIFIC REPORTS

Humans are host to a multitude of microorganisms that rapidly populate the body at birth, subject to a complex interplay that is d..

A twin study of body mass index and dental caries in childhood.

MJ Silva, NM Kilpatrick, JM Craig, DJ Manton, P Leong, H Ho, R Saffery, DP Burgner, KJ Scurrah

Journal article  |  2020  |  Scientific Reports

Sub-optimal nutrition and dental caries are both common with significant short and long-term implications for child health and dev..

Collecting biomarkers in Australian primary schools: Insights from the field

Mandy Truong, Mienah Sharif, Rebecca Moorhead, Jeffrey M Craig, Pamela Leong, Yuk Jing Loke, Kevin Dunn, Naomi Priest

Journal article  |  2020  |  SURVEY RESEARCH METHODS

There are increasing efforts to incorporate biology into studies on the social determinants of health. While there is increasing u..

Epigenetic Influences on Neurodevelopment at 11 Years of Age: Protocol for the Longitudinal Peri/Postnatal Epigenetic Twins Study at 11 Years of Age (PETS@11)

Pamela Leong, Yuk Jing Loke, Richard Saffery, Tim Silk, Alice Burnett, Elisha Josev, Katrina Scurrah, Christiane Theda, Anna Czajko, Emmanuel PK Pua, Marc L Seal, Jeffrey M Craig

Journal article  |  2019  |  TWIN RESEARCH AND HUMAN GENETICS

Neurodevelopment is sensitive to genetic and pre/postnatal environmental influences. These effects are likely mediated by epigenet..

Genetic and Early-Life Environmental Influences on Dental Caries Risk: A Twin Study

Mihiri J Silva, Nicky M Kilpatrick, Jeffrey M Craig, David J Manton, Pamela Leong, David P Burgner, Katrina J Scurrah

Journal article  |  2019  |  PEDIATRICS

OBJECTIVES: To explore the relative contributions of genetic and environmental influences on dental caries risk and to investigate..

Etiology of Hypomineralized Second Primary Molars: A Prospective Twin Study

MJ Silva, NM Kilpatrick, JM Craig, DJ Manton, P Leong, D Burgner, KJ Scurrah

Journal article  |  2019  |  JOURNAL OF DENTAL RESEARCH

The etiology of hypomineralized second primary molars (HSPM) is unclear, but genetic and environmental factors have been proposed...