Mariko Sasaki

The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts.

Shun Hosoyamada, Mariko Sasaki, Takehiko Kobayashi

Journal article  |  2019  |  Molecular and Cellular Biology

The rRNA genes (rDNA) in eukaryotes are organized into highly repetitive gene clusters. Each organism maintains a particular numbe..

Defects in the NuA4 acetyltransferase complex increase stability of the ribosomal RNA gene and extend replicative lifespan.

Tsuyoshi Wakatsuki, Mariko Sasaki, Takehiko Kobayashi

Journal article  |  2019  |  Genes & Genetic Systems

Genome instability is a cause of cellular senescence. The ribosomal RNA gene repeat (rDNA) is one of the most unstable regions in ..

Gender-specific association of early age-related macular degeneration with systemic and genetic factors in a Japanese population

Mariko Sasaki, Sei Harada, Yumiko Kawasaki, Miki Watanabe, Hidemi Ito, Hideo Tanaka, Ayano Takeuchi, Kazuo Tsubota, Toru Takebayashi, Yuji Nishiwaki, Ryo Kawasaki

Journal article  |  2018  |  Scientific Reports

Ctf4 Prevents Genome Rearrangements by Suppressing DNA Double-Strand Break Formation and Its End Resection at Arrested Replication Forks.

Mariko Sasaki, Takehiko Kobayashi

Journal article  |  2017  |  Molecular Cell

Arrested replication forks lead to DNA double-strand breaks (DSBs), which are a major source of genome rearrangements. Yet DSB rep..

Early Signs of Exudative Age-Related Macular Degeneration in Asians

Mariko Sasaki, Ryo Kawasaki, Atsuro Uchida, Takashi Koto, Hajime Shinoda, Kazuo Tsubota, Tien Yin Wong, Yoko Ozawa

Journal article  |  2014  |  Optometry and Vision Science

Association of Serum Lipids With Macular Thickness and Volume in Type 2 Diabetes Without Diabetic Macular Edema

Mariko Sasaki, Motoko Kawashima, Ryo Kawasaki, Atsuro Uchida, Takashi Koto, Hajime Shinoda, Kazuo Tsubota, Jie Jin Wang, Yoko Ozawa

Journal article  |  2014  |  Investigative Ophthalmology and Visual Science

Effect of simvastatin on retinal vascular caliber: the Age-Related Maculopathy Statin Study

Mariko Sasaki, Wei Lin Gan, Ryo Kawasaki, Lauren Hodgson, Kim Yu Lee, Tien Yin Wong, Ecosse Lamoureux, Liubov Robman, Robyn Guymer

Journal article  |  2013  |  Acta Ophthalmologica (Print)

Quantitative Measurement of Hard Exudates in Patients With Diabetes and Their Associations With Serum Lipid Levels

Mariko Sasaki, Ryo Kawasaki, Jonathan E Noonan, Tien Yin Wong, Ecosse Lamoureux, Jie Jin Wang

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science