Wenyi Li

The effect of tailing lipidation on the bioactivity of antimicrobial peptides and their aggregation tendency

Bruce Lin, Andrew Hung, William Singleton, Kevion K Darmawan, Rachael Moses, Bicheng Yao, Hongkang Wu, Anders Barlow, Marc‐Antoine Sani, Alastair J Sloan, Mohammed Akhter Hossain, John D Wade, Yuning Hong, Neil M O'Brien‐Simpson, Wenyi Li

Journal article  |  2023  |  Aggregate

The overview of antimicrobial peptide‐coated implants against oral bacterial infections

Zhe Sun, Li Ma, Xiaodong Sun, Alastair J Sloan, Neil M O'Brien‐Simpson, Wenyi Li

Journal article  |  2023  |  Aggregate

Star-Peptide Polymers are Multi-Drug-Resistant Gram-Positive Bacteria Killers

Wenyi Li, Sara Hadjigol, Alicia Rasines Mazo, James Holden, Jason Lenzo, Steven J Shirbin, Anders Barlow, Sadegh Shabani, Tao Huang, Eric C Reynolds, Greg G Qiao, Neil M O'Brien-Simpson

Journal article  |  2022  |  ACS APPLIED MATERIALS & INTERFACES

Antibiotic resistance in bacteria, especially Gram-positive bacteria like Staphylococcus aureus, is gaining considerable momentum ..

Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational Screening

Thomas NG Handley, Wenyi Li, Nicholas G Welch, Neil M O'Brien-Simpson, Mohammed Akhter Hossain, John D Wade

Journal article  |  2022  |  FRONTIERS IN CHEMISTRY

The day is rapidly approaching where current antibiotic therapies will no longer be effective due to the development of multi-drug..

Introduction to Special Issue on Advances in Peptide Therapeutics

Wenyi Li

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS

Development and application of Diels-Alder adducts displaying AIE properties

Timothy L Gialelis, Tze Cin Owyong, Siyang Ding, Wenyi Li, Maoxing Yu, Neil M O'Brien-Simpson, Zujin Zhao, Jonathan M White, Bicheng Yao, Yuning Hong

Journal article  |  2022  |  CELL REPORTS PHYSICAL SCIENCE

Exploring organic reactions to construct novel molecules with aggregation-induced emission (AIE) features is an essential branch o..

Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker

Wenyi Li, Feng Lin, Andrew Hung, Anders Barlow, Marc-Antoine Sani, Rita Paolini, William Singleton, James Holden, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Journal article  |  2022  |  CHEMICAL SCIENCE

Antimicrobial peptides (AMPs) are host defense peptides, and unlike conventional antibiotics, they possess potent broad spectrum a..

Discovery and Characterization of a New Crustin Antimicrobial Peptide from Amphibalanus amphitrite

Wei Zhang, Xiaohang Xu, Jun Zhang, Ting Ye, Qiao Zhou, Ying Xu, Wenyi Li, Zhangli Hu, Chenjing Shang

Journal article  |  2022  |  PHARMACEUTICS

Crustins are an antimicrobial peptide (AMP) family that plays an important role in innate immunity in crustaceans. It is important..

Systematic comparison of activity and mechanism of antimicrobial peptides against nosocomial pathogens

Bruce Lin, Andrew Hung, Rong Li, Anders Barlow, William Singleton, Tamara Matthyssen, Marc-Antoine D Sani, Mohammed Akhter Hossain, John Wade, Neil M O'Brien-Simpson, Wenyi Li

Journal article  |  2022  |  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The World Health Organisation has deemed several multi-drug resistant (MDR) nosocomial bacterial pathogens to be of significant th..

The Potential of Modified and Multimeric Antimicrobial Peptide Materials as Superbug Killers

Tamara Matthyssen, Wenyi Li, James A Holden, Jason C Lenzo, Sara Hadjigol, Neil M O'Brien-Simpson

Journal article  |  2022  |  FRONTIERS IN CHEMISTRY

Antimicrobial peptides (AMPs) are found in nearly all living organisms, show broad spectrum antibacterial activity, and can modula..