Wenyi Li

Recent Applications of Aggregation Induced Emission Probes for Antimicrobial Peptide Studies

Tracey Luu, Wenyi Li, Neil M O'Brien-Simpson, Yuning Hong

Journal article  |  2021  |  Chemistry - An Asian Journal

Antimicrobial peptides (AMPs) are being intensively investigated as they are considered promising alternatives to antibiotics wher..

Chemically modified and conjugated antimicrobial peptides against superbugs.

Wenyi Li, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Journal article  |  2021  |  Chemical Society Reviews

Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050, will lead to more deaths from bacteri..

Human glucose-dependent insulinotropic polypeptide (GIP) is an antimicrobial adjuvant re-sensitising multidrug-resistant Gram-negative bacteria

Da'san MM Jaradat, Nehaya Al-Karablieh, Basmah HM Zaarer, Wenyi Li, Khalil KY Saleh, Anas J Rasras, Saeid Abu-Romman, Neil M O'Brien-Simpson, John D Wade

Journal article  |  2021  |  Biological Chemistry

Abstract Increasing antibiotic resistance in Gram-negative bacteria has mandated the development of both novel anti..

(Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members

Nicholas G Welch, Wenyi Li, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade

Journal article  |  2020  |  Frontiers in Chemistry

As we rapidly approach a post-antibiotic era in which multi-drug resistant bacteria are ever-pervasive, antimicrobial peptides (AM..

Chemical Modification of Cellulose Membranes for SPOT Synthesis

Wenyi Li, John Wade, Eric Reynolds, Neil M O'Brien-Simpson

Journal article  |  2020  |  Australian Journal of Chemistry

Since the development of solid-phase peptide synthesis in the 1960s, many laboratories have modified the technology for the produc..

The 9-Fluorenylmethoxycarbonyl (Fmoc) Group in Chemical Peptide Synthesis - Its Past, Present, and Future

Wenyi Li, Neil M O'Brien-Simpson, Mohammed Akhter Hossain, John D Wade

Journal article  |  2020  |  Australian Journal of Chemistry: an international journal for chemical science

The chemical formation of the peptide bond has long fascinated and challenged organic chemists. It requires not only the activatio..

Effect of dimerized melittin on gastric cancer cells and antibacterial activity

Elaheh Jamasbi, Sasidharan S Lucky, Wenyi Li, Mohammed Akhter Hossain, Ponnampalam Gopalakrishnakone, Frances Separovic

Journal article  |  2018  |  AMINO ACIDS

Covalent conjugation of cationic antimicrobial peptides with a beta-lactam antibiotic core

Wenyi Li, Neil M O'Brien-Simpson, James A Holden, Laszlo Otvos, Eric C Reynolds, Frances Separovic, Mohammed Akhter Hossain, John D Wade

Journal article  |  2018  |  PEPTIDE SCIENCE

The Effect of Selective D- or N-alpha-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20

Wenyi Li, Zhe Sun, Neil M O'Brien-Simpson, Laszlo Otvos, Eric C Reynolds, Mohammed A Hossain, Frances Separovic, John D Walde

Journal article  |  2017  |  FRONTIERS IN CHEMISTRY

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide

Wenyi Li, Neil M O'Brien-Simpson, Shenggen Yao, Julien Tailhades, Eric C Reynolds, Raymond M Dawson, Laszlo Otvos, Mohammed Akhter Hossain, Frances Separovic, John D Wade

Journal article  |  2017  |  Chemistry - A European Journal