Vijay Rajagopal

Respiration mask waveguide optimisation for maximised speech intelligibility

Kirill Kolesnik, David Bryan, William Harley, Philipp Segeritz, Matthew Guest, Vijay Rajagopal, David J Collins

Journal article  |  2021  |  JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Both the scarcity and environmental impact of disposable face masks, as in the COVID-19 pandemic, have instigated the recent devel..

A toolbox for generating scalable mitral valve morphometric models

Diana C de Oliveira, Daniel M Espino, Luca Deorsola, Jonathan P Mynard, Vijay Rajagopal, Keith Buchan, Dana Dawson, Duncan ET Shepherd

Journal article  |  2021  |  COMPUTERS IN BIOLOGY AND MEDICINE

The mitral valve is a complex anatomical structure, whose shape is key to several traits of its function and disease, being crucia..

Unconventional acoustic approaches for localized and designed micromanipulation

Kirill Kolesnik, Mingxin Xu, Peter VS Lee, Vijay Rajagopal, David J Collins

Journal article  |  2021  |  LAB ON A CHIP

Acoustic fields are ideal for micromanipulation, being biocompatible and with force gradients approaching the scale of single cell..

EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

Juliana Gomez, Zammam Areeb, Sarah F Stuart, Hong PT Nguyen, Lucia Paradiso, Ahmad Zulkifli, Sonakshi Madan, Vijay Rajagopal, Magdalene K Montgomery, Hui K Gan, Andrew M Scott, Jordan Jones, Andrew H Kaye, Andrew P Morokoff, Rodney B Luwor

Journal article  |  2021  |  CANCERS

Reticulocalbin 1 (RCN1) is an endoplasmic reticulum (ER)-residing protein, involved in promoting cell survival during pathophysiol..

Cortical Tension Initiates the Positive Feedback Loop Between E-cadherin and F-actin

Qilin Yu, William Holmes, Jean Thiery, Rodney Luwor, Vijay Rajagopal

Journal article  |  2021

Adherens junctions (AJs) physically link two cells at their contact interface via extracellular homophilic interactions between ca..

Surface Area-to-Volume Ratio, not Cellular Viscoelasticity is the Major Determinant of Red Blood Cell Traversal through Small Channels

Arman Namvar, Adam Blanch, Matthew Dixon, Olivia Carmo, Boyin Liu, Snigdha Tiash, Oliver Looker, Dean Andrew, Li-Jin Chan, Wai-Hong Tham, Peter VS Lee, Vijay Rajagopat, Leann Tilley

Journal article  |  2021  |  BIOPHYSICAL JOURNAL

EM-stellar: benchmarking deep learning for electron microscopy image segmentation

Afshin Khadangi, Thomas Boudier, Vijay Rajagopal

Journal article  |  2021  |  BIOINFORMATICS

MOTIVATION: The inherent low contrast of electron microscopy (EM) datasets presents a significant challenge for rapid segmentation..

EM-net: Deep learning for electron microscopy image segmentation

Afshin Khadangi, Thomas Boudier, Vijay Rajagopal

Conference Proceedings  |  2021  |  2020 25TH INTERNATIONAL CONFERENCE ON PATTERN RECOGNITION (ICPR)

Recent high-throughput electron microscopy techniques such as focused ion-beam scanning electron microscopy (FIB-SEM) provide thou..

Membrane Tension Can Enhance Adaptation to Maintain Polarity of Migrating Cells

Cole Zmurchok, Jared Collette, Vijay Rajagopal, William R Holmes

Journal article  |  2020  |  BIOPHYSICAL JOURNAL

Migratory cells are known to adapt to environments that contain wide-ranging levels of chemoattractant. Although biochemical model..

Surface area-to-volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels.

Arman Namvar, Adam J Blanch, Matthew W Dixon, Olivia MS Carmo, Boyin Liu, Snigdha Tiash, Oliver Looker, Dean Andrew, Li-Jin Chan, Wai-Hong Tham, Peter VS Lee, Vijay Rajagopal, Leann Tilley

Journal article  |  2020  |  Cellular Microbiology

The remarkable deformability of red blood cells (RBCs) depends on the viscoelasticity of the plasma membrane and cell contents and..