Jess Nithianantharajah

Longitudinal hippocampal volumetric changes in mice following brain infarction

Vanessa H Brait, David K Wright, Mohsen Nategh, Alexander Oman, Warda T Syeda, Charlotte M Ermine, Katrina R O'Brien, Emilio Werden, Leonid Churilov, Leigh A Johnston, Lachlan H Thompson, Jess Nithianantharajah, Katherine A Jackman, Amy Brodtmann

Journal article  |  2021  |  SCIENTIFIC REPORTS

Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, including stroke and vascular cogniti..

Focal Ischemic Injury to the Early Neonatal Rat Brain Models Cognitive and Motor Deficits with Associated Histopathological Outcomes Relevant to Human Neonatal Brain Injury

Brett J Kagan, Charlotte M Ermine, Stefano Frausin, Clare L Parish, Jess Nithianantharajah, Lachlan H Thompson

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neonatal arterial ischemic stroke is one of the more severe birth complications. The injury can result in extensive neurological d..

Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2

Alexa E Horner, Rebecca H Norris, Robbie McLaren-Jones, Liam Alexander, Noboru H Komiyama, Seth GN Grant, Jess Nithianantharajah, Maksym Kopanitsa

Journal article  |  2020  |  GENES BRAIN AND BEHAVIOR

The postsynaptic terminal of vertebrate excitatory synapses contains a highly conserved multiprotein complex that comprises neurot..

Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia

Cassandra J Hatzipantelis, Monica Langiu, Teresa H Vandekolk, Tracie L Pierce, Jess Nithianantharajah, Gregory D Stewart, Christopher J Langmead

Journal article  |  2020  |  ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

There are no effective therapeutics for cognitive impairments associated with schizophrenia (CIAS), which includes deficits in exe..

MicroRNA-210 Regulates Dendritic Morphology and Behavioural Flexibility in Mice

Michelle Watts, Gabrielle Williams, Jing Lu, Jess Nithianantharajah, Charles Claudianos

Journal article  |  2020  |  MOLECULAR NEUROBIOLOGY

MicroRNAs are known to be critical regulators of neuronal plasticity. The highly conserved, hypoxia-regulated microRNA-210 (miR-21..

ET-1 INDUCED FOCAL ISCHEMIA IN ADULT RATS CAUSES CHANGES IN BRAIN VOLUME AND HIPPOCAMPAL NEUROGENESIS UP TO 12 MONTHS FOLLOWING INJURY.

C Ermine, K O'Brien, J Kauhausen, S Frausin, A Oman, V Brait, W Syeda, D Wright, E Werden, L Johnston, J Nithianantharajah, A Brodtmann, L Thompson

Conference Proceedings  |  2020  |  INTERNATIONAL JOURNAL OF STROKE

REMOTE LONG-TERM STRUCTURAL BRAIN CHANGES IN ADULT RATS 48 WEEKS AFTER FOCAL ISCHEMIC STROKE

W Syeda, C Ermine, V Brait, L Thompson, J Nithianantharajah, E Werden, L Johnston, A Brodtmann

Conference Proceedings  |  2020  |  INTERNATIONAL JOURNAL OF STROKE

LONGITUDINAL HIPPOCAMPAL NEURODEGENERATION AND MICROGLIOSIS FOLLOWING ACUTE ISCHEMIC STROKE IN MICE

A Oman, M Nategh, V Brait, C Ermine, W Syeda, L Johnston, E Werden, J Nithianantharajah, L Thompson, A Brodtmann

Conference Proceedings  |  2020  |  INTERNATIONAL JOURNAL OF STROKE

Neurological, neuropsychiatric and neurodevelopmental complications of COVID-19

Christos Pantelis, Mahesh Jayaram, Anthony J Hannan, Robb Wesselingh, Jess Nithianantharajah, Cassandra MJ Wannan, Warda Taqdees Syeda, KH Christopher Choy, Daniela Zantomio, Arthur Christopoulos, Dennis Velakoulis, Terence J O'Brien

Journal article  |  2020  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Although COVID-19 is predominantly a respiratory disease, it is known to affect multiple organ systems. In this article, we highli..

A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1

Jiaqi Luo, Jessica M Tan, Jess Nithianantharajah

Journal article  |  2020  |  BMC BIOLOGY

BACKGROUND: In a changing environment, a challenge for the brain is to flexibly guide adaptive behavior towards survival. Complex ..