Lucy Palmer

Cocaine regulates sensory filtering in cortical pyramidal neurons

Sean C Murphy, Luca Godenzini, Robertas Guzulaitis, Andrew J Lawrence, Lucy M Palmer

Journal article  |  2023  |  CELL REPORTS

Exposure to cocaine leads to robust changes in the structure and function of neurons within the mesocorticolimbic pathway. However..

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

Guilherme Testa-Silva, Marius Rosier, Suraj Honnuraiah, Robertas Guzulaitis, Ana Morello Megias, Chris French, James King, Katharine Drummond, Lucy M Palmer, Greg J Stuart

Journal article  |  2022  |  CELL REPORTS

Neurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in ..

Neural basis of anticipation and premature impulsive action in the frontal cortex

Robertas Guzulaitis, Luca Godenzini, Lucy Maree Palmer

Journal article  |  2022  |  NATURE NEUROSCIENCE

Planning motor actions can improve behavioral performance; however, it can also lead to premature actions. Although the anterior l..

Dendritic Mechanisms for In Vivo Neural Computations and Behavior

Lukas Fischer, Raul Mojica Soto-Albors, Vincent D Tang, Brendan Bicknell, Christine Grienberger, Valerio Francioni, Richard Noud, Lucy M Palmer, Naoya Takahashi

Journal article  |  2022  |  JOURNAL OF NEUROSCIENCE

Dendrites receive the vast majority of a single neuron's inputs, and coordinate the transformation of these signals into neuronal ..

Intracellular calcium release: A conductor of compartmentalized dendritic plasticity

Lucy M Palmer

Journal article  |  2022  |  CELL

Dendrites endow neurons with multiple compartments within their elaborate morphologies. In a recent study published in the journal..

Dendritic Compartmentalization of Learning-Related Plasticity

Luca Godenzini, Adam S Shai, Lucy M Palmer

Journal article  |  2022  |  ENEURO

The dendrites of cortical pyramidal neurons receive synaptic inputs from different pathways that are organized according to their ..

Local and Global Dynamics of Dendritic Activity in the Pyramidal Neuron

George Stuyt, Luca Godenzini, Lucy M Palmer

Journal article  |  2022  |  NEUROSCIENCE

There has been increasing interest in the measurement and comparison of activity across compartments of the pyramidal neuron. Dend..

The role of higher-order thalamus during learning and correct performance in goal-directed behavior

Danilo La Terra, Ann-Sofie Bjerre, Marius Rosier, Rei Masuda, Tomas J Ryan, Lucy M Palmer

Journal article  |  2022  |  ELIFE

The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the..

Auditory input enhances somatosensory encoding and tactile goal-directed behavior

L Godenzini, D Alwis, R Guzulaitis, S Honnuraiah, GJ Stuart, LM Palmer

Journal article  |  2021  |  NATURE COMMUNICATIONS

The capacity of the brain to encode multiple types of sensory input is key to survival. Yet, how neurons integrate information fro..

Probing Cortical Activity During Head-Fixed Behavior

Ann-Sofie Bjerre, Lucy M Palmer

Journal article  |  2020  |  FRONTIERS IN MOLECULAR NEUROSCIENCE

The cortex is crucial for many behaviors, ranging from sensory-based behaviors to working memory and social behaviors. To gain an ..