Ruslan Pustovit

Investigation of nerve pathways mediating colorectal dysfunction in Parkinson's disease model produced by lesion of nigrostriatal dopaminergic neurons

Xin-yi Chai, Shanti Diwakarla, Ruslan V Pustovit, Rachel M McQuade, Madeleine Di Natale, Charlotte M Ermine, Clare L Parish, David I Finkelstein, John B Furness

Journal article  |  2020  |  Neurogastroenterology & Motility

BACKGROUND: Gastrointestinal (GI) dysfunction, including constipation, is a common non-motor symptom of Parkinson's disease (PD). ..

Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5-HT4 agonism and cholinesterase inhibition

Yasuhiro Tsukimi, Ruslan V Pustovit, Andrea M Harrington, Sonia Garcia-Caraballo, Stuart M Brierley, Madeleine Di Natale, Juan C Molero, John B Furness

Journal article  |  2020  |  Neurogastroenterology & Motility

BACKGROUND: Muscarinic receptor 1 positive allosteric modulators (M1PAMs) enhance colonic propulsive contractions and defecation t..

Effects of M1 receptor positive allosteric modulators on colorectal function

Ruslan Pustovit, Yasuhiro Tsukimi, Yasuo Itomi, Mitchell Ringuet, Madeleine Di Natale, Juan C Molero, JB Furness

Conference Proceedings  |  2020  |  NEUROGASTROENTEROLOGY AND MOTILITY

Distant effects on the colon following 6-hydroxydopamine lesioning of the medial forebrain bundle

Xin-yi Chai, Shanti Diwakarla, Ruslan V Pustovit, Rachel M McQuade, Madeleine Di Natale, Charlotte M Ermine, Clare L Parish, David I Finkelstein, John B Furness

Conference Proceedings  |  2020  |  NEUROGASTROENTEROLOGY AND MOTILITY

Dopamine/ghrelin receptor heteromers and their roles in lumbo-sacral defecation centres

Mitchell T Ringuet, Ruslan V Pustovit, Andrea Fanjul, Andrew Syder, Jie Huang, Lindsay Yoo, Sebastian GB Furness, Linda J Fothergill, Wendy Winchester, Paul Wade, Jill Wykosky, John B Furness

Conference Proceedings  |  2020  |  NEUROGASTROENTEROLOGY AND MOTILITY

Muscarinic receptor 1 allosteric modulators stimulate colorectal emptying in dog, mouse and rat and resolve constipation

Ruslan V Pustovit, Yasuo Itomi, Mitchell Ringuet, Shanti Diwakarla, Xin-yi Chai, Rachel M McQuade, Yasuhiro Tsukimi, John B Furness

Journal article  |  2019  |  Neurogastroenterology & Motility

The involvement of dopamine, but not ghrelin, in physiological control of defecation through ghrelin receptors

J Furness, R Pustovit

Conference Proceedings  |  2018  |  NEUROGASTROENTEROLOGY AND MOTILITY

Neural pathways for colorectal control, relevance to spinal cord injury and treatment: a narrative review

Brid Callaghan, John B Furness, Ruslan V Pustovit

Journal article  |  2018  |  Spinal Cord

Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

Ruslan V Pustovit, Brid Callaghan, Mitchell T Ringuet, Nicole F Kerr, Billie Hunne, Ian M Smyth, Claudio Pietra, John B Furness

Journal article  |  2017  |  PHYSIOLOGICAL REPORTS

Effects of chromium supplementation on physiology, feed intake, and insulin related metabolism in growing pigs subjected to heat stress

F Liu, JJ Cottrell, U Wijesiriwardana, FW Kelly, SS Chauhan, RV Pustovit, PA Gonzales-Rivas, K DiGiacomo, BJ Leury, P Celi, FR Dunshea

Journal article  |  2017  |  Translational Animal Science