Ed Stanley

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L).

Yudha Nur Patria, Tayla Stenta, Jinia Lilianty, Lynn Rowley, Edouard G Stanley, Andrew G Elefanty, John F Bateman, Shireen R Lamandé

Journal article  |  2020  |  Stem Cell Research

To produce in vitro models of human chondrodysplasias caused by dominant missense mutations in TRPV4, we used CRISPR/Cas9 gene edi..

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

Monica Nafria, Peter Keane, Elizabeth S Ng, Edouard G Stanley, Andrew G Elefanty, Constanze Bonifer

Journal article  |  2020  |  Cell Reports

Acute myeloid leukemia (AML) is a hematopoietic malignancy caused by recurrent mutations in genes encoding transcriptional, chroma..

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

Jinia Lilianty, Yudha Nur Patria, Edouard G Stanley, Andrew G Elefanty, John F Bateman, Shireen R Lamande

Journal article  |  2020  |  Stem Cell Research

To produce an in vitro model of the human chondrodysplasia, spondyloepiphyseal dysplasia congenita, we used CRISPR/Cas9 gene editi..

Multipotent RAG1 progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

Ali Motazedian, Freya F Bruveris, Santhosh V Kumar, Jacqueline V Schiesser, Tyrone Chen, Elizabeth S Ng, Ann P Chidgey, Christine A Wells, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2020  |  Nature Cell Biology

Defining the ontogeny of the human adaptive immune system during embryogenesis has implications for understanding childhood diseas..

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

Yudha Nur Patria, Jinia Lilianty, Andrew G Elefanty, Edouard G Stanley, Tanya Labonne, John F Bateman, Shireen R Lamande

Journal article  |  2020  |  Stem Cell Research

To develop an iPSC SOX9 reporter line for monitoring differentiation into SOX9 expressing cells such as chondrocytes, cranial neur..

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

Kriti Joshi, Colleen Elso, Ali Motazedian, Tanya Labonne, Jacqueline V Schiesser, Fergus Cameron, Stuart I Mannering, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2019  |  Diabetologia

AIMS/HYPOTHESIS: Type 1 diabetes is an autoimmune disorder characterised by loss of insulin-producing beta cells of the pancreas. ..

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

Deevina Arasaratnam, Katrina M Bell, Choon Boon Sim, Kathy Koutsis, David J Anderson, Elizabeth L Qian, Edouard G Stanley, Andrew G Elefanty, Michael M Cheung, Alicia Oshlack, Anthony J White, Charbel Abi Khalil, James E Hudson, Enzo R Porrello, David A Elliott

Journal article  |  2019  |  Scientific Reports

MicroRNAs (miRNAs) are translational regulatory molecules with recognised roles in heart development and disease. Therefore, it is..

Generation of seven iPSC lines from peripheral blood mononuclear cells suitable to investigate Autism Spectrum Disorder

Kiymet Bozaoglu, Yujing Gao, Edouard Stanley, Miriam Fanjul-Fernandez, Natasha J Brown, Kate Pope, Cherie C Green, Katerina Vlahos, Koula Sourris, Melanie Bahlo, Martin Delatycki, Ingrid Scheffer, Paul J Lockhart

Journal article  |  2019  |  Stem Cell Research

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G > T iPSC line and an isogenic control iPSC line

Sara Howden, Hani Hosseini Far, Ali Motazedian, Andrew G Elefanty, Edouard G Stanley, Shireen R Lamande, John F Bateman

Journal article  |  2019  |  Stem Cell Research

To develop a disease model for the human 'brittle bone' disease, osteogenesis imperfecta, we used a simultaneous reprogramming and..

PRODUCTION OF IPSCS FROM A SMALL VOLUME OF CRYOPRESERVED HUMAN UMBILICAL CORD BLOOD BUFFY COAT UNDER "GMP-COMPLIANT" CONDITIONS

P Tian, K Abberton, A Elefanty, E Stanley, J Hollands, L Thompson, N Elwood

Conference Proceedings  |  2019  |  Cytotherapy

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

Hani Hosseini Far, Yudha Nur Patria, Ali Motazedian, Andrew G Elefanty, Edouard G Stanley, Shireen R Lamande, John F Bateman

Journal article  |  2019  |  Stem Cell Research

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

Santhosh Kumar, Pei X Er, Kynan T Lawlor, Ali Motazedian, Michelle Scurr, Irene Ghobrial, Alexander N Combes, Luke Zappia, Alicia Oshlack, Edouard G Stanley, Melissa H Little

Journal article  |  2019  |  Development

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

Katerina Vlahos, Koula Sourris, Robyn Mayberry, Penelope McDonald, Freya F Bruveris, Jacqueline V Schiesser, Kiymet Bozaoglu, Paul J Lockhart, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2019  |  Stem Cell Research

Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells

Thomas F Allison, Peter W Andrews, Yishai Avior, Ivana Barbaric, Nissim Benvenisty, Christoph Bock, Jennifer Brehm, Oliver Bruestle, Ivan Damjanov, Andrew Elefanty, Daniel Felkner, Paul J Gokhale, Florian Halbritter, Lyn E Healy, Tim X Hu, Barbara B Knowles, Jeanne F Loring, Tenneille E Ludwig, Robyn Mayberry, Suzanne Micallef, et al.

Journal article  |  2018  |  Nature Communications

EXPANDING CELLULAR THERAPIES THROUGH PROVISION OF A CORD BLOOD-DERIVED IPSC HAPLOBANK

N Elwood, K Abberton, P Tian, A Elefanty, E Stanley, J Youngson, M Diviney, R Holdsworth, K Tiedemann, M Little

Conference Proceedings  |  2018  |  CYTOTHERAPY

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

David J Anderson, David I Kaplan, Katrina M Bell, Katerina Koutsis, John M Haynes, Richard J Mills, Dean G Phelan, Elizabeth L Qian, Ana Rita Leitoguinho, Deevina Arasaratnam, Tanya Labonne, Elizabeth S Ng, Richard P Davis, Simona Casini, Robert Passier, James E Hudson, Enzo R Porrello, Mauro W Costa, Arash Rafii, Clare L Curl, et al.

Journal article  |  2018  |  Nature Communications

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease

Yujing Gao, Gabrielle R Wilson, Kiymet Bozaoglu, Andrew G Elefanty, Edouard G Stanley, Mirella Dottori, Paul J Lockhart

Journal article  |  2018  |  Stem Cell Research

WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development

Jenna Richter, Edouard G Stanley, Elizabeth S Ng, Andrew G Elefanty, David Traver, Karl Willert

Journal article  |  2018  |  Genes

Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces

Jack W Lambshead, Laurence Meagher, Jacob Goodwin, Tanya Labonne, Elizabeth Ng, Andrew Elefanty, Edouard Stanley, Carmel M O'Brien, Andrew L Laslett

Journal article  |  2018  |  Scientific Reports

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

Kesavan Meganathan, Emily MA Lewis, Paul Gontarz, Shaopeng Liu, Edouard G Stanley, Andrew G Elefanty, James E Huettner, Bo Zhang, Kristen L Kroll

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination

Jae Young Lee, Min Joung Kim, Devy Deliyanti, Michael F Azari, Fernando Rossello, Adam Costin, Georg Ramm, Edouard G Stanley, Andrew G Elefanty, Jennifer L Wilkinson-Berka, Steven Petratos

Journal article  |  2017  |  EBioMedicine

Cell membrane thyroid hormone (TH) transport can be facilitated by the monocarboxylate transporter 8 (MCT8), encoded by the solute..

RUNX1c Regulates Hematopoietic Differentiation of Human Pluripotent Stem Cells Possibly in Cooperation with Proinflammatory Signaling

Oscar Navarro-Montero, Veronica Ayllon, Mar Lamolda, Lourdes Lopez-Onieva, Rosa Montes, Clara Bueno, Elizabeth Ng, Xiomara Guerrero-Carreno, Tamara Romero, Damia Romero-Moya, Ed Stanley, Andrew Elefanty, Veronica Ramos-Mejia, Pablo Menendez, Pedro J Real

Journal article  |  2017  |  STEM CELLS

Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells

Stephanie F Bellmaine, Dmitry A Ovchinnikov, David T Manallack, Claire E Cuddy, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Spencer J Williams, Martin Pera

Journal article  |  2017  |  eLife

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

Yangfei Xiang, Yoshiaki Tanaka, Benjamin Patterson, Young-Jin Kang, Gubbi Govindaiah, Naomi Roselaar, Bilal Cakir, Kun-Yong Kim, Adam P Lombroso, Sung-Min Hwang, Mei Zhong, Edouard G Stanley, Andrew G Elefanty, Janice R Naegele, Sang-Hun Lee, Sherman M Weissman, In-Hyun Park

Journal article  |  2017  |  Cell Stem Cell

Human haematopoietic stem cell development: from the embryo to the dish

Andrejs Ivanovs, Stanislav Rybtsov, Elizabeth S Ng, Edouard G Stanley, Andrew G Elefanty, Alexander Medvinsky

Journal article  |  2017  |  Development

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes

Jennifer Pasquier, Renuka Gupta, Damien Rioult, Jessica Hoarau-Vechot, Raphael Courjaret, Khaled Machaca, Jassim Al Suwaidi, Edouard G Stanley, Shahin Rafii, David A Elliott, Charbel Abi Khalil, Arash Rafii

Journal article  |  2017  |  The Journal of Heart and Lung Transplantation

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Jonathan C Niclis, Carlos W Gantner, Walaa F Alsanie, Stuart J McDougall, Chris R Bye, Andrew G Elefanty, Edouard G Stanley, John M Haynes, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  STEM CELLS Translational Medicine

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

Michael J Workman, Maxime M Mahe, Stephen Trisno, Holly M Poling, Carey L Watson, Nambirajan Sundaram, Ching-Fang Chang, Jacqueline Schiesser, Philippe Aubert, Edouard G Stanley, Andrew G Elefanty, Yuichiro Miyaoka, Mohammad A Mandegar, Bruce R Conklin, Michel Neunlist, Samantha A Brugmann, Michael A Helmrath, James M Wells

Journal article  |  2017  |  Nature Medicine

Differentiation of human embryonic stem cells to HOXA( ) hemogenic vasculature that resembles the aorta-gonad-mesonephros

Elizabeth S Ng, Lisa Azzola, Freya F Bruveris, Vincenzo Calvanese, Belinda Phipson, Katerina Vlahos, Claire Hirst, Vanta J Jokubaitis, Qing C Yu, Jovana Maksimovic, Simone Liebscher, Vania Januar, Zhen Zhang, Brenda Williams, Aude Conscience, Jennifer Durnall, Steven Jackson, Magdaline Costa, David Elliott, David N Haylock, et al.

Journal article  |  2016  |  Nature Biotechnology

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

Tim Kao, Tanya Labonne, Jonathan C Niclis, Ritu Chaurasia, Zerina Lokmic, Elizabeth Qian, Freya F Bruveris, Sara E Howden, Ali Motazedian, Jacqueline V Schiesser, Magdaline Costa, Koula Sourris, Elizabeth Ng, David Anderson, Antonietta Giudice, Peter Farlie, Michael Cheung, Shireen R Lamande, Anthony J Penington, Clare L Parish, et al.

Journal article  |  2016  |  STEM CELL REPORTS

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

Sara E Howden, Bradley McColl, Astrid Glaser, Jim Vadolas, Steven Petrou, Melissa H Little, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2016  |  Stem Cell Reports

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy(aEuro)

Dean G Phelan, David J Anderson, Sara E Howden, Raymond CB Wong, Peter F Hickey, Kate Pope, Gabrielle R Wilson, Alice Pebay, Andrew M Davis, Steven Petrou, Andrew G Elefanty, Edouard G Stanley, Paul A James, Ivan Macciocca, Melanie Bahlo, Michael M Cheung, David J Amor, David A Elliott, Paul J Lockhart

Journal article  |  2016  |  European Heart Journal

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells

Melany Jackson, Rui Ma, Helen Taylor, Richard A Axton, Jennifer Easterbrook, Maria Kydonaki, Emmanuel Olivier, Lamin Marenah, Edouard G Stanley, Andrew G Elefanty, Joanne C Mountford, Lesley M Forrester

Journal article  |  2016  |  STEM CELLS Translational Medicine

Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

James F Markmann, Stephen T Bartlett, Paul Johnson, Olle Korsgren, Bernhard J Hering, David Scharp, Thomas WH Kay, Jonathan Bromberg, Jon S Odorico, Gordon C Weir, Nancy Bridges, Raja Kandaswamy, Peter Stock, Peter Friend, Mitsukazu Gotoh, David KC Cooper, Chung-Gyu Park, Philip J O'Connell, Cherie Stabler, Shinichi Matsumoto, et al.

Journal article  |  2016  |  Transplantation

Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement

Stephen T Bartlett, James F Markmann, Paul Johnson, Olle Korsgren, Bernhard J Hering, David Scharp, Thomas WH Kay, Jonathan Bromberg, Jon S Odorico, Gordon C Weir, Nancy Bridges, Raja Kandaswamy, Peter Stock, Peter Friend, Mitsukazu Gotoh, David KC Cooper, Chung-Gyu Park, Phillip O'Connell, Cherie Stabler, Shinichi Matsumoto, et al.

Journal article  |  2016  |  Transplantation

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

Rhys JP Skelton, Bevin Brady, Suhail Khoja, Debashis Sahoo, James Engel, Deevina Arasaratnam, Kholoud K Saleh, Oscar J Abilez, Peng Zhao, Edouard G Stanley, Andrew G Elefanty, Murray Kwon, David A Elliott, Reza Ardehali

Journal article  |  2016  |  Stem Cell Reports

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

Rhys JP Skelton, Suhail Khoja, Shone Almeida, Stanislas Rapacchi, Fei Han, James Engel, Peng Zhao, Peng Hu, Edouard G Stanley, Andrew G Elefanty, Murray Kwon, David A Elliott, Reza Ardehali

Journal article  |  2016  |  STEM CELLS Translational Medicine

Spatio-temporal re-organization of replication foci accompanies replication domain consolidation during human pluripotent stem cell lineage specification

Korey A Wilson, Andrew G Elefanty, Edouard G Stanley, David M Gilbert

Journal article  |  2016  |  Cell Cycle

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

Sara E Howden, John P Maufort, Bret M Duffin, Andrew G Elefanty, Edouard G Stanley, James A Thomson

Journal article  |  2015  |  STEM CELL REPORTS

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts.

Sara E Howden, John P Maufort, Bret M Duffin, Andrew G Elefanty, Edouard G Stanley, James A Thomson

Journal article  |  2015  |  Stem Cell Reports

The derivation of genetically modified induced pluripotent stem (iPS) cells typically involves multiple steps, requiring lengthy c..

Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1( ) Respiratory Progenitors With Human Rhinovirus

Robert A Jenny, Claire Hirst, Sue Mei Lim, Adam L Goulburn, Suzanne J Micallef, Tanya Labonne, Anthony Kicic, Kak-Ming Ling, Stephen M Stick, Elizabeth S Ng, Alan Trounson, Antonietta Giudice, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2015  |  STEM CELLS Translational Medicine

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Zerina Lokmic, Elizabeth S Ng, Matthew Burton, Edouard G Stanley, Anthony J Penington, Andrew G Elefanty

Journal article  |  2015  |  Journal of Visualized Experiments

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

Andrea Ditadi, Christopher M Sturgeon, Joanna Tober, Geneve Awong, Marion Kennedy, Amanda D Yzaguirre, Lisa Azzola, Elizabeth S Ng, Edouard G Stanley, Deborah L French, Xin Cheng, Paul Gadue, Nancy A Speck, Andrew G Elefanty, Gordon Keller

Journal article  |  2015  |  Nature Cell Biology

Efficient Generation of NKX6-1( ) Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines

M Cristina Nostro, Farida Sarangi, Chaoxing Yang, Andrew Holland, Andrew G Elefanty, Edouard G Stanley, Dale L Greiner, Gordon Keller

Journal article  |  2015  |  Stem Cell Reports

beta-cell regeneration and differentiation: how close are we to the 'holy grail'?

Gemma Tan, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2014  |  Journal of Molecular Endocrinology

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny

Julie Cao, Elizabeth S Ng, Don McNaughton, Edouard G Stanley, Andrew G Elefanty, Mark J Tobin, Philip Heraud

Journal article  |  2014  |  Journal of Biophotonics

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development

Rhys JP Skelton, Magdaline Costa, David J Anderson, Freya Bruveris, Ben W Finnin, Katerina Koutsis, Deevina Arasaratnam, Anthony J White, Arash Rafii, Elizabeth S Ng, Andrew G Elefanty, Edouard G Stanley, Colin W Pouton, John M Haynes, Reza Ardehali, Richard P Davis, Christine L Mummery, David A Elliott

Journal article  |  2014  |  Stem Cell Research

FOXN1(GFP/w) Reporter hESCs Enable Identification of Integrin-beta 4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXNI ( ) Thymic Epithelial Progenitors

Chew-Li Soh, Antonietta Giudice, Robert A Jenny, David A Elliott, Tanya Hatzistavrou, Suzanne J Micallef, Korosh Kianizad, Natalie Seach, Juan Carlos Zuniga-Pfluecker, Ann P Chidgey, Alan Trounson, Susan K Nilsson, David N Haylock, Richard L Boyd, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2014  |  Stem Cell Reports

Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

Kyle M Loh, Lay Teng Ang, Jingyao Zhang, Vibhor Kumar, Jasmin Ang, Jun Qiang Auyeong, Kian Leong Lee, Siew Hua Choo, Christina YY Lim, Massimo Nichane, Junru Tan, Monireh Soroush Noghabi, Lisa Azzola, Elizabeth S Ng, Jens Durruthy-Durruthy, Vittorio Sebastiano, Lorenz Poellinger, Andrew G Elefanty, Edouard G Stanley, Qingfeng Chen, et al.

Journal article  |  2014  |  Cell Stem Cell

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

M Takasato, PX Er, M Becroft, JM Vanslambrouck, EG Stanley, AG Elefanty, MH Little

Journal article  |  2014  |  Nature Cell Biology

Derivation of insulin-producing beta-cells from human pluripotent stem cells.

Jacqueline V Schiesser, Suzanne J Micallef, Susan Hawes, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2014  |  The Review of Diabetic Studies

Human embryonic stem cells have been advanced as a source of insulin-producing cells that could potentially replace cadaveric-deri..

PGC-1 alpha and Reactive Oxygen Species Regulate Human Embryonic Stem Cell-Derived Cardiomyocyte Function

Matthew J Birket, Simona Casini, Georgios Kosmidis, David A Elliott, Akos A Gerencser, Antonius Baartscheer, Cees Schumacher, Pier G Mastroberardino, Andrew G Elefanty, Ed G Stanley, Christine L Mummery

Journal article  |  2013  |  Stem Cell Reports

The Characterisation of Pluripotent and Multipotent Stem Cells Using Fourier Transform Infrared Microspectroscopy

Julie Cao, Elizabeth S Ng, Donald McNaughton, Edouard G Stanley, Andrew G Elefanty, Mark J Tobin, Philip Heraud

Journal article  |  2013  |  International Journal of Molecular Sciences

Rewiring Immunity: Generating a Functional Thymus from hESCs ... Are We There Yet?

Richard L Boyd, Chew-Li Soh, Nicholas R Boyd, Edouard G Stanley, Ann P Chidgey

Journal article  |  2013  |  Cell Stem Cell

An outpatient low-intensity locomotor training programme for paediatric chronic incomplete spinal cord injury

CM O'Donnell, AR Harvey

Journal article  |  2013  |  Spinal Cord

WNT3A Promotes Hematopoietic or Mesenchymal Differentiation from hESCs Depending on the Time of Exposure

Karin Gertow, Claire E Hirst, Qing C Yu, Elizabeth S Ng, Lloyd A Pereira, Richard P Davis, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2013  |  Stem Cell Reports

Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development

Cory R Nicholas, Jiadong Chen, Yunshuo Tang, Derek G Southwell, Nadine Chalmers, Daniel Vogt, Christine M Arnold, Ying-Jiun J Chen, Edouard G Stanley, Andrew G Elefanty, Yoshiki Sasai, Arturo Alvarez-Buylla, John LR Rubenstein, Arnold R Kriegstein

Journal article  |  2013  |  Cell Stem Cell

Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells

Asif M Maroof, Sotirios Keros, Jennifer A Tyson, Shui-Wang Ying, Yosif M Ganat, Florian T Merkle, Becky Liu, Adam Goulburn, Edouard G Stanley, Andrew G Elefanty, Hans Ruedi Widmer, Kevin Eggan, Peter A Goldstein, Stewart A Anderson, Lorenz Studer

Journal article  |  2013  |  Cell Stem Cell

Generation of Megakaryocytic Progenitors from Human Embryonic Stem Cells in a Feeder- and Serum-Free Medium

Marjorie Pick, Lisa Azzola, Elissa Osborne, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2013  |  PLoS ONE

Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers but Do Not Form Contractile Cardiomyocytes

Christophe M Raynaud, Najeeb Halabi, David A Elliott, Jennifer Pasquier, Andrew G Elefanty, Edouard G Stanley, Arash Rafii

Journal article  |  2013  |  PLoS ONE

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells

Julie Cao, Elizabeth S Ng, Don McNaughton, Edouard G Stanley, Andrew G Elefanty, Mark J Tobin, Philip Heraud

Journal article  |  2013  |  The Analyst

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Magdaline Costa, Koula Sourris, Sue Mei Lim, Qing C Yu, Claire E Hirst, Helena C Parkington, Vanta J Jokubaitis, Anthony E Dear, Hong B Liu, Suzanne J Micallef, Kathy Koutsis, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2013  |  Stem Cell Research

Microbioreactor Arrays for Full Factorial Screening of Exogenous and Paracrine Factors in Human Embryonic Stem Cell Differentiation

Drew M Titmarsh, James E Hudson, Alejandro Hidalgo, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Justin J Cooper-White

Journal article  |  2012  |  PLoS ONE

Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro

Andrew BJ Prowse, Fenny Chong, David A Elliott, Andrew G Elefanty, Edouard G Stanley, Peter P Gray, Trent P Munro, Geoffrey W Osborne

Journal article  |  2012  |  PLoS ONE

The Mix family of homeobox genes-Key regulators of mesendoderm formation during vertebrate development

Lloyd A Pereira, Michael S Wong, Sue Mei Lim, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2012  |  Developmental Biology

Temporal Restriction of Pancreatic Branching Competence During Embryogenesis Is Mirrored In Differentiating Embryonic Stem Cells

Sue Mei Lim, Xueling Li, Jacqueline Schiesser, Andrew M Holland, Andrew G Elefanty, Edouard G Stanley, Suzanne J Micallef

Journal article  |  2012  |  Stem Cells and Development

APELIN promotes hematopoiesis from human embryonic stem cells

Qing C Yu, Claire E Hirst, Magdaline Costa, Elizabeth S Ng, Jacqueline V Schiesser, Karin Gertow, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2012  |  Blood

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

Katsutsugu Umeda, Jiangang Zhao, Paul Simmons, Edouard Stanley, Andrew Elefanty, Naoki Nakayama

Journal article  |  2012  |  Scientific Reports

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells

Adam L Goulburn, Edouard G Stanley, Andrew G Elefanty, Stewart A Anderson

Journal article  |  2012  |  Stem Cell Research

Pdgfr alpha and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells

Lloyd A Pereira, Michael S Wong, Anna K Mossman, Koula Sourris, Mary E Janes, Kathy Knezevic, Claire E Hirst, Sue Mei Lim, John E Pimanda, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2012  |  Stem Cell Research

INSGFP/w human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

SJ Micallef, X Li, JV Schiesser, CE Hirst, QC Yu, SM Lim, MC Nostro, DA Elliott, F Sarangi, LC Harrison, G Keller, AG Elefanty, EG Stanley

Journal article  |  2012  |  Diabetologia

The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells

CL Basford, KJ Prentice, AB Hardy, F Sarangi, SJ Micallef, X Li, Q Guo, AG Elefanty, EG Stanley, G Keller, EM Allister, MC Nostro, MB Wheeler

Journal article  |  2012  |  Diabetologia

Efficient generation of adipocytes in a dish

Andrew G Elefanty, Edouard G Stanley

Journal article  |  2012  |  Nature Cell Biology

Brachyury and Related Tbx Proteins Interact with the Mixl1 Homeodomain Protein and Negatively Regulate Mixl1 Transcriptional Activity

Lloyd A Pereira, Michael S Wong, Sue Mei Lim, Alexandra Sides, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2011  |  PLoS ONE

NKX2-5eGFPw hESCs for isolation of human cardiac progenitors and cardiomyocytes

David A Elliott, Stefan R Braam, Katerina Koutsis, Elizabeth S Ng, Robert Jenny, Ebba L Lagerqvist, Christine Biben, Tanya Hatzistavrou, Claire E Hirst, Qing C Yu, Rhys JP Skelton, Dorien Ward-van Oostwaard, Sue Mei Lim, Ouda Khammy, Xueling Li, Susan M Hawes, Richard P Davis, Adam L Goulburn, Robert Passier, Owen WJ Prall, et al.

Journal article  |  2011  |  NATURE METHODS

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells

Nicole C Dubois, April M Craft, Parveen Sharma, David A Elliott, Edouard G Stanley, Andrew G Elefanty, Anthony Gramolini, Gordon Keller

Journal article  |  2011  |  Nature Biotechnology

Generation of Human Female Reproductive Tract Epithelium from Human Embryonic Stem Cells

Louie Ye, Robyn Mayberry, Camden Y Lo, Kara L Britt, Edouard G Stanley, Andrew G Elefanty, Caroline E Gargett

Journal article  |  2011  |  PLoS ONE

Stage-specific signaling through TGF beta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells

M Cristina Nostro, Farida Sarangi, Shinichiro Ogawa, Audrey Holtzinger, Barbara Corneo, Xueling Li, Suzanne J Micallef, In-Hyun Park, Christina Basford, Michael B Wheeler, George Q Daley, Andrew G Elefanty, Edouard G Stanley, Gordon Keller

Journal article  |  2011  |  Development

A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives

Adam L Goulburn, Darym Alden, Richard P Davis, Suzanne J Micallef, Elizabeth S Ng, Qing C Yu, Sue Mei Lim, Chew-Li Soh, David A Elliott, Tanya Hatzistavrou, Justin Bourke, Bradley Watmuff, Richard J Lang, John M Haynes, Colin W Pouton, Antonietta Giudice, Alan O Trounson, Stewart A Anderson, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2011  |  STEM CELLS

Defined substrates for pluripotent stem cells: are we there yet?

Andrew G Elefanty, Edouard G Stanley

Journal article  |  2010  |  Nature Methods

Differentiating Embryonic Stem Cells Pass through 'Temporal Windows' That Mark Responsiveness to Exogenous and Paracrine Mesendoderm Inducing Signals

Steven A Jackson, Jacqueline Schiesser, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2010  |  PLoS ONE

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells

Philip Heraud, Elizabeth S Ng, Sally Caine, Qing C Yu, Claire Hirst, Robyn Mayberry, Amanda Bruce, Bayden R Wood, Don McNaughton, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2010  |  Stem Cell Research

Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices

Qizhi Chen, Liyu Jin, Wayne D Cook, Dirk Mohn, Ebba L Lagerqvist, David A Elliott, John M Haynes, Nicholas Boyd, Wendelin J Stark, Colin W Pouton, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2010  |  Soft Matter

Expression from a beta geo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system

Claire E Hirst, Sue-Mei Lim, Lloyd A Pereira, Robyn A Mayberry, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2010  |  The International Journal of Developmental Biology

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination.

Richard P Davis, Catarina Grandela, Koula Sourris, Tanya Hatzistavrou, Mirella Dottori, Andrew G Elefanty, Edouard G Stanley, Magdaline Costa

Book Chapter  |  2009  |  Current Protocols in Stem Cell Biology

This unit describes a series of technical procedures to form clonal human embryonic stem cell (hESC) lines that are genetically mo..

ErythRED, a hESC line enabling identification of erythroid cells

Tanya Hatzistavrou, Suzanne J Micallef, Elizabeth S Ng, Jim Vadolas, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2009  |  Nature Methods

Reshaping pluripotent stem cells

Andrew G Elefanty, Edouard G Stanley

Journal article  |  2009  |  Nature Biotechnology

Pancreatic differentiation from pluripotent stem cells: Tweaking the system

Andrew M Holland, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2009  |  Cell Research

Enforced Expression of Mixl1 During Mouse ES Cell Differentiation Suppresses Hematopoietic Mesoderm and Promotes Endoderm Formation

Sue Mei Lim, Lloyd Pereira, Michael S Wong, Claire E Hirst, Benjamin E Van Vranken, Marjorie Pick, Alan Trounson, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2009  |  Stem Cells

Stems cells and the price of immortality.

Andrew M Holland, Edouard G Stanley

Journal article  |  2009  |  Stem Cell Research

Expansion of human embryonic stem cells in vitro.

Magdaline Costa, Koula Sourris, Tanya Hatzistavrou, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2008  |  Current Protocols in Stem Cell Biology

This unit describes a protocol for the large-scale expansion of karyotypically normal human embryonic stem cells (hESCs). hESCs ca..

Building better beta cells

Edouard G Stanley, Andrew G Elefanty

Journal article  |  2008  |  Cell Stem Cell

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors

Richard P Davis, Elizabeth S Ng, Magdaline Costa, Anna K Mossman, Koula Sourris, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2008  |  Blood

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay.

Elizabeth S Ng, Richard P Davis, Tanya Hatzistavrou, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2008  |  Current Protocols in Stem Cell Biology

This unit describes a protocol for the differentiation of human embryonic stem cells (hESCs). To generate spin embryoid bodies (EB..

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

Richard P Davis, Magdaline Costa, Catarina Grandela, Andrew M Holland, Tanya Hatzistavrou, Suzanne J Micallef, Xueling Li, Adam L Goulburn, Lisa Azzola, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2008  |  Nature Protocols

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

Elizabeth S Ng, Richard Davis, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2008  |  Nature Protocols

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

Suzanne J Micallef, Xueling Li, Mary E Janes, Steven A Jackson, Robyn M Sutherland, Andrew M Lew, Leonard C Harrison, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2007  |  Stem Cell Res.

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in Hematopoiesis

Marjorie Pick, Lisa Azzola, Anna Mossman, Edouard G Stanley, Andrew G Elefanty

Journal article  |  2007  |  STEM CELLS

Pancreas differentiation of mouse ES cells.

Suzanne J Micallef, Xueling Li, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2007  |  Current protocols in stem cell biology

This unit describes the derivation of pancreatic cells from mouse embryonic stem cells (ESCs). Mouse ESCs are pluripotent immortal..

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis

Leigh Coultas, Susanna Terzano, Tim Thomas, Anne Voss, Kate Reid, Edouard G Stanley, Clare L Scott, Philippe Bouillet, Perry Bartlett, Jonathan Ham, Jerry M Adams, Andreas Strasser

Journal article  |  2007  |  J. Cell Sci.

Germ layer induction in ESC--following the vertebrate roadmap.

Jim Smith, Fiona Wardle, Matt Loose, Ed Stanley, Roger Patient

Journal article  |  2007  |  Current Protocols in Stem Cell Biology

Controlled differentiation of pluripotential cells takes place routinely and with great success in developing vertebrate embryos. ..

A method for genetic modification of human embryonic stem cells using electroporation

Magdaline Costa, Mirella Dottori, Koula Sourris, Pegah Jamshidi, Tanya Hatzistavrou, Richard Davis, Lisa Azzola, Steven Jackson, Sue Mei Lim, Martin Pera, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2007  |  Nature Protocols

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function

Andrew M Holland, Suzanne J Micallef, Xueling Li, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2006  |  GENESIS

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

Andrew M Holland, Suzanne J Micallef, Xueling Li, Andrew G Elefanty, Edouard G Stanley

Journal article  |  2006  |  genesis

The pancreatic and duodenal homeobox gene 1 (Pdx1) has multiple roles in the specification and development of foregut endoderm-der..

Transcriptional profiling of mouse and human ES. cells identifies SLAIN1, a novel stem cell gene

CE Hirst, ES Ng, L Azzola, AK Voss, T Thomas, EG Stanley, AG Elefanty

Journal article  |  2006  |  Dev. Biol.

Mix11 and Oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells

AK Mossman, K Sourris, E Ng, EG Stanley, AG Elefanty

Journal article  |  2005  |  Stem Cells and Development

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation

ES Ng, RP Davis, L Azzola, EG Stanley, AG Elefanty

Journal article  |  2005  |  Blood

The hESC line Envy expresses high levels of GFP in all differentiated progeny

M Costa, M Dottori, E Ng, SM Hawes, K Sourris, P Jamshidi, MF Pera, AG Elefanty, EG Stanley

Journal article  |  2005  |  Nature Methods

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

ES Ng, L Azzola, K Sourris, L Robb, EG Stanley, AG Elefanty

Journal article  |  2005  |  Development

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells

SJ Micallef, ME Janes, K Knezevic, RP Davis, AG Elefanty, EG Stanley

Journal article  |  2005  |  Diabetes

Characterization of mice lacking the tetraspanin superfamily member CD151

MD Wright, SM Geary, S Fitter, GW Moseley, LM Lau, KC Sheng, V Apostolopoulos, EG Stanley, DE Jackson, LK Ashman

Journal article  |  2004  |  Molecular and Cellular Biology

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin

MF Pera, J Andrade, S Houssami, B Reubinoff, A Trounson, EG Stanley, D Ward-van Oostwaard, C Mummery

Journal article  |  2004  |  Journal of Cell Science

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

L Coultas, P Bouillet, EG Stanley, TC Brodnicki, JM Adams, A Strasser

Journal article  |  2004  |  Mol. Cell. Biol.

Erratum: Journal of Cell Biology (September 15, 2003) 162:6 (1089-1098)

VC Foletta, MA Lim, J Soosairajah, AP Kelly, EG Stanley, M Shannon, W He, S Das, J Massagué, O Bernard

Journal article  |  2003  |  Journal of Cell Biology

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

VC Foletta, MA Lim, J Soosairaiah, AP Kelly, EG Stanley, M Shannon, W He, S Das, J Massague, O Bernard

Journal article  |  2003  |  Journal of Cell Biology

SOCS3 negatively regulates IL-6 signaling in vivo

BA Croker, DL Krebs, JG Zhang, S Wormald, TA Willson, EG Stanley, L Robb, CJ Greenhalgh, I Forster, BE Clausen, NA Nicola, D Metcalf, DJ Hilton, AW Roberts, WS Alexander

Journal article  |  2003  |  Nat. Immunol.

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8( ) T cell differentiation

MMW Chong, AL Cornish, R Darwiche, EG Stanley, JF Purton, DI Godfrey, DJ Hilton, R Starr, WS Alexander, TWH Kay

Journal article  |  2003  |  IMMUNITY

Efficient cre-mediated deletion in cardiac progenitor cells conferred by a 3′UTR-ires-Cre allele of the homeobox gene Nkx2-5

EG Stanley, C Biben, A Elefanty, L Barnett, F Koentgen, L Robb, RP Harvey

Journal article  |  2002  |  International Journal of Developmental Biology

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

AH Hart, L Hartley, K Sourris, ES Stadler, RL Li, EG Stanley, PPL Tam, AG Elefanty, L Robb

Journal article  |  2002  |  Development

Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells.

Fang-Xu Jiang, Edouard G Stanley, L Jorge Gonez, Leonard C Harrison

Journal article  |  2002  |  Journal of Cell Science

Extracellular signals that guide pancreas cell development are not well characterized. In an in vitro culture system of dissociate..

Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells

FX Jiang, EG Stanley, LJ Gonez, LC Harrison

Journal article  |  2002  |  JOURNAL OF CELL SCIENCE

Efficient cre-mediated deletion in cardiac progenitor cells conferred by a 3 ' UTR-ires-Cre allele of the homeobox gene Nkx2-5

EG Stanley, C Biben, A Elefanty, L Barnett, F Koentgen, L Robb, RP Harvey

Journal article  |  2002  |  INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5

C Biben, R Weber, S Kesteven, E Stanley, L McDonald, DA Elliott, L Barnett, F Koentgen, L Robb, M Feneley, RP Harvey

Journal article  |  2000  |  Circulation Research

Targeted insertion of a lacZ reporter gene into the mouse Cer1 locus reveals complex and dynamic expression during embryogenesis

EG Stanley, C Biben, J Allison, L Hartley, IP Wicks, IK Campbell, M McKinley, L Barnett, F Koentgen, L Robb, RP Harvey

Journal article  |  2000  |  genesis

Human cerberus related gene CER1 maps to chromosome 9

M Lah, T Brodnicki, P Maccarone, A Nash, E Stanley, RP Harvey

Journal article  |  1999  |  Genomics

DAN is a secreted glycoprotein related to Xenopus cerberus

E Stanley, C Biben, S Kotecha, L Fabri, S Tajbakhsh, CC Wang, T Hatzistavrou, B Roberts, C Drinkwater, M Lah, M Buckingham, D Hilton, A Nash, T Mohun, RP Harvey

Journal article  |  1998  |  Mechanisms of Development

Murine cerberus homologue Cer1 maps to chromosome 4

E Stanley, DG Gilbert, NA Jenkins, NG Copeland, RP Harvey

Journal article  |  1998  |  Genomics

Murine cerberus homologue mCer-1: A candidate anterior patterning molecule

C Biben, E Stanley, L Fabri, S Kotecha, M Rhinn, C Drinkwater, M Lah, CC Wang, A Nash, D Hilton, SL Ang, T Mohun, RP Harvey

Journal article  |  1998  |  Developmental Biology

AUTOPHOSPHORYLATION INDUCES AUTOACTIVATION AND A DECREASE IN THE SRC HOMOLOGY-2 DOMAIN ACCESSIBILITY OF THE LYN PROTEIN-KINASE

N SOTIRELLIS, TM JOHNSON, ML HIBBS, IJ STANLEY, E STANLEY, AR DUNN, HC CHENG

Journal article  |  1995  |  Journal of Biological Chemistry

IDENTIFICATION OF A DUPLICATION OF THE MOUSE LYN GENE

ML HIBBS, E STANLEY, R MAGLITTO, AR DUNN

Journal article  |  1995  |  Gene

MICE LACKING GRANULOCYTE-COLONY-STIMULATING FACTOR HAVE CHRONIC NEUTROPENIA, GRANULOCYTE AND MACROPHAGE PROGENITOR-CELL DEFICIENCY, AND IMPAIRED NEUTROPHIL MOBILIZATION

GJ LIESCHKE, D GRAIL, G HODGSON, D METCALF, E STANLEY, C CHEERS, KJ FOWLER, S BASU, YF ZHAN, AR DUNN

Journal article  |  1994  |  Blood

MICE LACKING BOTH MACROPHAGE-MACROPHAGE AND GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR HAVE MACROPHAGES AND COEXISTENT OSTEOPETROSIS AND SEVERE LUNG-DISEASE

GJ LIESCHKE, E STANLEY, D GRAIL, G HODGSON, V SINICKAS, JAM GALL, RA SINCLAIR, AR DUNN

Journal article  |  1994  |  Blood

GRANULOCYTE/MACROPHAGE COLONY-STIMULATING FACTOR-DEFICIENT MICE SHOW NO MAJOR PERTURBATION OF HEMATOPOIESIS BUT DEVELOP A CHARACTERISTIC PULMONARY PATHOLOGY

E STANLEY, GJ LIESCHKE, D GRAIL, D METCALF, G HODGSON, JAM GALL, DW MAHER, J CEBON, V SINICKAS, AR DUNN

Journal article  |  1994  |  Proceedings of the National Academy of Sciences

LIPOPOLYSACCHARIDE-GAMMA-INDUCED AND INTERFERON-GAMMA-INDUCED EXPRESSION OF HCK AND LYN TYROSINE KINASES IN MURINE BONE MARROW-DERIVED MACROPHAGES

I BOULET, S RALPH, E STANLEY, P LOCK, AR DUNN, SP GREEN, WA PHILLIPS

Journal article  |  1992  |  Oncogene

Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.

P Lock, S Ralph, E Stanley, I Boulet, R Ramsay, AR Dunn

Journal article  |  1991  |  Molecular and Cellular Biology

Mammalian hck, a member of the src family of tyrosine kinases, is expressed predominantly in cells of the myeloid and B-lymphoid l..

2 ISOFORMS OF MURINE HCK, GENERATED BY UTILIZATION OF ALTERNATIVE TRANSLATIONAL INITIATION CODONS, EXHIBIT DIFFERENT PATTERNS OF SUBCELLULAR-LOCALIZATION

P LOCK, S RALPH, E STANLEY, I BOULET, R RAMSAY, AR DUNN

Journal article  |  1991  |  MOLECULAR AND CELLULAR BIOLOGY

ALTERNATIVELY SPLICED MURINE LYN MESSENGER-RNAS ENCODE DISTINCT PROTEINS

E STANLEY, S RALPH, S MCEWEN, I BOULET, DA HOLTZMAN, P LOCK, AR DUNN

Journal article  |  1991  |  Molecular and Cellular Biology

FUNCTIONAL-ANALYSIS AND NUCLEOTIDE-SEQUENCE OF THE PROMOTER REGION OF THE MURINE HCK GENE

P LOCK, E STANLEY, DA HOLTZMAN, AR DUNN

Journal article  |  1990  |  Molecular and Cellular Biology

MURINE EPIDERMAL GROWTH-FACTOR - STRUCTURE AND FUNCTION

AW BURGESS, CJ LLOYD, S SMITH, E STANLEY, F WALKER, L FABRI, RJ SIMPSON, EC NICE

Journal article  |  1988  |  Biochemistry

TRANSGENIC MICE EXPRESSING A HEMATOPOIETIC GROWTH-FACTOR GENE (GM-CSF) DEVELOP ACCUMULATIONS OF MACROPHAGES, BLINDNESS, AND A FATAL SYNDROME OF TISSUE-DAMAGE

RA LANG, D METCALF, RA CUTHBERTSON, I LYONS, E STANLEY, A KELSO, G KANNOURAKIS, DJ WILLIAMSON, GK KLINTWORTH, TJ GONDA, AR DUNN

Journal article  |  1987  |  Cell

THE STRUCTURE AND EXPRESSION OF THE MURINE GENE ENCODING GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR - EVIDENCE FOR UTILIZATION OF ALTERNATIVE PROMOTERS

E STANLEY, D METCALF, P SOBIESZCZUK, NM GOUGH, AR DUNN

Journal article  |  1985  |  The EMBO Journal