Fiona Angrisano

Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton

Elizabeth S Zuccala, Timothy J Satchwell, Fiona Angrisano, Yan Hong Tan, Marieangela C Wilson, Kate J Heesom, Jake Baum

Journal article  |  2016  |  SCIENTIFIC REPORTS

The invasive blood-stage malaria parasite - the merozoite - induces rapid morphological changes to the target erythrocyte during e..

Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites

Maya A Olshina, Fiona Angrisano, Danushka S Marapana, David T Riglar, Kartik Bane, Wilson Wong, Bruno Catimel, Meng-Xin Yin, Andrew B Holmes, Friedrich Frischknecht, David R Kovar, Jake Baum

Journal article  |  2015  |  MALARIA JOURNAL

BACKGROUND: Gliding motility in Plasmodium parasites, the aetiological agents of malaria disease, is mediated by an actomyosin mot..

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

Danny W Wilson, Christopher D Goodman, Brad E Sleebs, Greta E Weiss, Nienke WM de Jong, Fiona Angrisano, Christine Langer, Jake Baum, Brendan S Crabb, Paul R Gilson, Geoffrey I McFadden, James G Beeson

Journal article  |  2015  |  BMC BIOLOGY

BACKGROUND: Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibito..

A Mechanism for Actin Filament Severing by Malaria Parasite Actin Depolymerizing Factor 1 via a Low Affinity Binding Interface

Wilson Wong, Andrew I Webb, Maya A Olshina, Giuseppe Infusini, Yan Hong Tan, Eric Hanssen, Bruno Catimel, Cristian Suarez, Melanie Condron, Fiona Angrisano, Thomas Neb, David R Kovar, Jake Baum

Journal article  |  2014  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Actin depolymerizing factor (ADF)/cofilins are essential regulators of actin turnover in eukaryotic cells. These multifunctional p..

Cell-Cell Communication between Malaria-Infected Red Blood Cells via Exosome-like Vesicles

Neta Regev-Rudzki, Danny W Wilson, Teresa G Carvalho, Xavier Sisquella, Bradley M Coleman, Melanie Rug, Dejan Bursac, Fiona Angrisano, Michelle Gee, Andrew F Hill, Jake Baum, Alan F Cowman

Journal article  |  2013  |  CELL

Cell-cell communication is an important mechanism for information exchange promoting cell survival for the control of features suc..

A GFP-Actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle

Fiona Angrisano, Michael J Delves, Angelika Sturm, Vanessa Mollard, Geoffrey I McFadden, Robert E Sinden, Jake Baum

Journal article  |  2012  |  MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Malaria parasite motility relies on an internal parasite actomyosin motor that, when linked to the host cell substrate, propels mo..

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

David T Riglar, Dave Richard, Danny W Wilson, Michelle J Boyle, Chaitali Dekiwadia, Lynne Turnbull, Fiona Angrisano, Danushka S Marapana, Kelly L Rogers, Cynthia B Whitchurch, James G Beeson, Alan F Cowman, Stuart A Ralph, Jake Baum

Journal article  |  2011  |  CELL HOST & MICROBE

Erythrocyte invasion by the merozoite is an obligatory stage in Plasmodium parasite infection and essential to malaria disease pro..