Anita Horvath

Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor

Laura K Young, Nigel P Birch, Peter J Browett, Paul B Coughlin, Anita J Horvath, Neil S Van de Water, Paul A Ockelford, Paul L Harper

Journal article  |  2012  |  Thrombosis and Haemostasis

The X-ray Crystal Structure of Full-Length Human Plasminogen

Ruby HP Law, Tom Caradoc-Davies, Nathan Cowieson, Anita J Horvath, Adam J Quek, Joanna Amarante Encarnacao, David Steer, Angus Cowan, Qingwei Zhang, Bernadine GC Lu, Robert N Pike, A Ian Smith, Paul B Coughlin, James C Whisstock

Journal article  |  2012  |  Cell Reports

Contribution of Conserved Lysine Residues in the alpha(2)-Antiplasmin C Terminus to Plasmin Binding and Inhibition

Bernadine GC Lu, Trifina Sofian, Ruby HP Law, Paul B Coughlin, Anita J Horvath

Journal article  |  2011  |  Journal of Biological Chemistry

METHODS TO MEASURE THE KINETICS OF PROTEASE INHIBITION BY SERPINS

Anita J Horvath, Bernadine GC Lu, Robert N Pike, Stephen R Bottomley

Book Chapter  |  2011  |  Methods in Enzymology

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid

Be'eri Niego, Anita Horvath, Paul B Coughlin, Michael K Pugsley, Robert L Medcalf

Journal article  |  2008  |  Blood Coagulation & Fibrinolysis

X-ray crystal structure of the fibrinolysis inhibitor alpha(2)-antiplasmin

Ruby HP Law, Trifina Sofian, Wan-Ting Kan, Anita J Horvath, Corinne R Hitchen, Christopher G Langendorf, Ashley M Buckle, James C Whisstock, Paul B Coughlin

Journal article  |  2008  |  Blood

Molecular characterization of centerin, a germinal centre cell serpin

Melinda A Paterson, Anita J Horvath, Robert N Pike, Paul B Coughlin

Journal article  |  2007  |  Biochemical Journal

The murine orthologue of human antichymotrypsin - A structural paradigm for CLADE A3 serpins

AJ Horvath, JA Irving, J Rossjohn, RH Law, SP Bottomley, NS Quinsey, RN Pike, PB Coughlin, JC Whisstock

Journal article  |  2005  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization.

Ingrid G Winkler, Jean Hendy, Paul Coughlin, Anita Horvath, Jean-Pierre Lévesque

Journal article  |  2005  |  Journal of Experimental Medicine

Mobilization of hematopoietic progenitor cells into the blood involves a massive release of neutrophil serine proteases in the bon..

Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the serpina3 locus

AJ Horvath, SL Forsyth, PB Coughlin

Journal article  |  2004  |  Journal of Molecular Evolution

Murine serpin 2A is a redox-sensitive intracellular protein

EC Morris, TR Dafforn, SL Forsyth, MA Missen, AJ Horvath, L Hampson, IN Hampson, G Currie, RW Carrell, PB Coughlin

Journal article  |  2003  |  Biochemical Journal

A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.

Sharon Forsyth, Anita Horvath, Paul Coughlin

Journal article  |  2003  |  Genomics

The major human plasma protease inhibitors, alpha(1)-antitrypsin and alpha(1)-antichymotrypsin, are each encoded by a single gene,..

Isolation, characterisation and expression of mRNAs encoding the ovine CC chemokines, monocyte chemoattractant protein (MCP)-1 alpha and -2

J Dunphy, A Horvath, G Barcham, A Balic, R Bischof, E Meeusen

Journal article  |  2001  |  Veterinary Immunology and Immunopathology

Isolation and characterization of a novel inducible mammalian galectin

JL Dunphy, A Balic, GJ Barcham, AJ Horvath, AD Nash, ENT Meeusen

Journal article  |  2000  |  JOURNAL OF BIOLOGICAL CHEMISTRY