Cameron Johnstone

FGF13 promotes metastasis of triple-negative breast cancer

Cameron N Johnstone, Andrew D Pattison, Paul F Harrison, David R Powell, Peter Lock, Matthias Ernst, Robin L Anderson, Traude H Beilharz

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF CANCER

Triple-negative breast cancer (TNBC) represents 10-20% of all human ductal adenocarcinomas and has a poor prognosis relative to ot..

Estrogen receptor regulated miR-342 suppresses a pro-metastatic gene network

Rachael Lumb, Victoria K Arnet, Cameron N Johnstone, Katherine A Pillman, John Toubia, Emily Hackett-Jones, Caroline A Phillips, Pannapa Pinweha, Suraya Roslan, Xiaochun Li, Traude Beilharz, Yeesim Khew-Goodall, Gregory J Goodall, Robin L Anderson, Philip A Gregory

Conference Proceedings  |  2019  |  Oncology Abstracts

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic, Andrew J Dalley, Mariska Miranda, Caroline Atkinson, Simote T Foliaki, Kaltin Ferguson, Colleen Niland, Cameron N Johnstone, Victoria Lewis, Steven J Collins, Sunil R Lakhani, Fares Al-Ejeh, Andreas Moller

Journal article  |  2019  |  JCI INSIGHT

Anthracyclines are amongst the most effective chemotherapeutics ever developed, but they produce grueling side-effects, serious ad..

Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer

Cameron N Johnstone, Andrew D Pattison, Kylie L Gorringe, Paul F Harrison, David R Powell, Peter Lock, David Baloyan, Matthias Ernst, Alastair G Stewart, Traude H Beilharz, Robin L Anderson

Journal article  |  2018  |  DISEASE MODELS & MECHANISMS

Triple-negative breast cancer (TNBC) represents 10-20% of all human ductal adenocarcinomas and has a poor prognosis relative to ot..

Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential

Ebony R Fietz, Christine R Keenan, Guillermo Lopez-Campos, Yan Tu, Cameron N Johnstone, Trudi Harris, Alastair G Stewart

Journal article  |  2017  |  SCIENTIFIC REPORTS

Glucocorticoids are commonly used to prevent chemotherapy-induced nausea and vomiting despite a lack of understanding of their dir..

Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer

Cameron N Johnstone, Ashwini Chand, Tracy L Putoczki, Matthias Ernst

Journal article  |  2015  |  CYTOKINE & GROWTH FACTOR REVIEWS

Interleukin (IL)-11 is a member of the IL-6 family of cytokines that is defined by the shared use of the GP130 signal transducing ..

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease

Benjamin B Williams, Niall C Tebbutt, Michael Buchert, Tracy L Putoczki, Karen Doggett, Shisan Bao, Cameron N Johnstone, Frederick Masson, Frederic Hollande, Antony W Burgess, Andrew M Scott, Matthias Ernst, Joan K Heath

Journal article  |  2015  |  DISEASE MODELS & MECHANISMS

The cells of the intestinal epithelium provide a selectively permeable barrier between the external environment and internal tissu..

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

Cameron N Johnstone, Yvonne E Smith, Yuan Cao, Allan D Burrows, Ryan SN Cross, Xiawei Ling, Richard P Redvers, Judy P Doherty, Bedrich L Eckhardt, Anthony L Natoli, Christina M Restall, Erin Lucas, Helen B Pearson, Siddhartha Deb, Kara L Britt, Alexandra Rizzitelli, Jason Li, Judith H Harmey, Normand Pouliot, Robin L Anderson

Journal article  |  2015  |  DISEASE MODELS & MECHANISMS

The translation of basic research into improved therapies for breast cancer patients requires relevant preclinical models that inc..

Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor

Nuha Al-Zaubai, Cameron N Johnstone, May May Leong, John Li, Mark Rizzacasa, Alastair G Stewart

Journal article  |  2014  |  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Inflammation has been implicated in tumor initiation, angiogenesis, and metastasis, and linked to the development of more aggressi..

BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity

Yuan Cao, Clare Y Slaney, Bradley N Bidwell, Belinda S Parker, Cameron N Johnstone, Jai Rautela, Bedrich L Eckhardt, Robin L Anderson

Journal article  |  2014  |  CANCER RESEARCH

The TGFβ growth factor family member BMP4 is a potent suppressor of breast cancer metastasis. In the mouse, the development of hig..