Fiona Brownfoot

Uncovering the molecular cause of preeclampsia - The role of glutathionylation of the Na /K ATPase transporter.

Fiona Brownfoot

Journal article  |  2021  |  The Journal of Clinical Endocrinology & Metabolism

Management of late preterm preeclampsia: a comparison of maternal and fetal indications for delivery

Stephanie Galibert, Emerson Keenan, Roxanne Hastie, Fiona C Brownfoot

Journal article  |  2021  |  The Journal of Maternal-Fetal & Neonatal Medicine

OBJECTIVE: To investigate delivery indications for women with late preterm preeclampsia and evaluate whether disease characteristi..

Novel approaches to combat preeclampsia: from new drugs to innovative delivery

Natasha de Alwis, Natalie K Binder, Sally Beard, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Fiona Brownfoot, Natalie J Hannan

Journal article  |  2020  |  Placenta

Preeclampsia is a complex disease affecting 2-8% of pregnancies worldwide. It poses significant risk of maternal and perinatal mor..

Esomeprazole and sulfasalazine in combination additively reduce sFlt-1 secretion and diminish endothelial dysfunction: potential for a combination treatment for preeclampsia

Natalie K Binder, Fiona C Brownfoot, Sally Beard, Ping Cannon, Tuong V Nguyen, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Natalie J Hannan

Journal article  |  2020  |  Pregnancy Hypertension

Development and repurposing of therapies that show promise in the prevention or treatment of preeclampsia would be a major advance..

Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia.

Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Fiona Brownfoot, Catherine Cluver, Natalie Hannan

Journal article  |  2020  |  American Journal of Obstetrics and Gynecology

There has been increasing research momentum to identify new therapeutic agents for the prevention or treatment of preeclampsia, dr..

Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia

Fiona C Brownfoot, Roxanne Hastie, Natalie J Hannan, Ping Cannon, Tuong Nguyen, Laura Tuohey, Cathy Cluver, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2020  |  Placenta

INTRODUCTION: The antiangiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sENG) are elevated in p..

Pravastatin as the statin of choice for reducing pre-eclampsia-associated endothelial dysfunction

Natasha de Alwis, Sally Beard, Yeukai T Mangwiro, Natalie K Binder, Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Stephen Tong, Natalie J Hannan

Journal article  |  2020  |  Pregnancy Hypertension

OBJECTIVES: There is avid interest in pravastatin as a therapeutic intervention for pre-eclampsia, however little is known on stat..

Accuracy of clinical suspicion of growth restriction at term despite a normal growth ultrasound: A retrospective cohort study

Brittany Green, Lisa Hui, Roxanne Hastie, Stephen Tong, Fiona C Brownfoot

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

Entropy Profiling for Detection of Fetal Arrhythmias in Short Length Fetal Heart Rate Recordings

Emerson Keenan, Radhagayrathi K Udhayakumar, Chandan K Karmakar, Fiona C Brownfoot, Marimuthu Palaniswami

Conference Proceedings  |  2020  |  Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

The use of fetal heart rate (FHR) recordings for assessing fetal wellbeing is an integral component of obstetric care. Recently, n..

The incidence of hypertensive disorders of pregnancy following sperm donation in IVF: an Australian state-wide retrospective cohort study

Amber L Kennedy, Cathryn J Stern, Stephen Tong, Roxanne Hastie, Franca Agresta, Susan P Walker, Fiona C Brownfoot, Vivien MacLachlan, Beverley J Vollenhoven, Anthea C Lindquist

Journal article  |  2019  |  Human Reproduction

STUDY QUESTION: Does IVF using donor sperm increase the risk of hypertensive disorders of pregnancy and fetal growth restriction (..