Fiona Brownfoot

Influence of the photopolymerization matrix on the indicator response of optical fiber pH sensors

KJ Lee, PK Capon, H Ebendorff-Heidepriem, E Keenan, F Brownfoot, EP Schartner

Journal article  |  2023  |  Sensors and Actuators B: Chemical

Optical fiber pH sensors work by observing a change in the indicator's optical signal caused by variations in pH and these indicat..

Sulfasalazine for the treatment of preeclampsia in a nitric oxide synthase antagonist mouse model.

Natalie K Binder, Natasha de Alwis, Sally Beard, Elif Kadife, Alesia Harper, Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Natalie J Hannan

Journal article  |  2023  |  Placenta

INTRODUCTION: Development of a therapeutic that targets the pathophysiological elements of preeclampsia would be a major advance f..

SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas

Elif Kadife, Alesia Harper, Natasha De Alwis, Keegan Chien, Natalie Hannan, Fiona CC Brownfoot

Journal article  |  2023  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intrauterine growth restriction (IUGR), predominantly caused by placental insufficiency, affects partitioning of nutrients to the ..

The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health

Natasha de Alwis, Natalie K Binder, Sally Beard, Yeukai Tm Mangwiro, Elif Kadife, James SM Cuffe, Emerson Keenan, Bianca R Fato, Tu'uhevaha J Kaituiu-Lino, Fiona C Brownfoot, Sarah A Marshall, Natalie J Hannan

Journal article  |  2022  |  LIFE SCIENCE ALLIANCE

Preeclampsia affects ∼2-8% of pregnancies worldwide. It is associated with increased long-term maternal cardiovascular disease ris..

An estriol-eluting pessary to treat pelvic organ prolapse.

Jingjunjiao Long, Ghada Zidan, Ali Seyfoddin, Stephen Tong, Fiona C Brownfoot, Prathima Chowdary

Journal article  |  2022  |  Sci Rep

Pelvic organ prolapse affects up to 50% of parous women. Commonly used treatment options have unwelcome attributes; pessaries can ..

The effect of metformin on cardiovascular markers in female mice consuming a high fat diet.

Natasha de Alwis, Natalie K Binder, Yeukai TM Mangwiro, Natasha Pritchard, Sally Beard, Tu'uhevaha J Kaitu'u-Lino, Fiona Brownfoot, Natalie J Hannan

Journal article  |  2022  |  Obes Res Clin Pract

BACKGROUND: Metformin, widely used to treat diabetes, is now considered a candidate therapeutic for treatment of cardiovascular di..

Use of Metformin to Prolong Gestation in Preterm Preeclampsia

CA Cluver, R Hiscock, EH Decloedt, DR Hall, S Schell, BW Mol, F Brownfoot, TJ Kaitu'u-Lino, SP Walker, S Tong

Journal article  |  2022  |  Obstetric Anesthesia Digest

Associations Between Soluble fms-Like Tyrosine Kinase-1 and Placental Growth Factor and Disease Severity Among Women With Preterm Eclampsia and Preeclampsia

Roxanne Hastie, Lina Bergman, Susan P Walker, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan, Fiona Brownfoot, Sonja Schell, Alesia Harper, Ping Cannon, Catherine A Cluver, Stephen Tong

Journal article  |  2022  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

Background The angiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) are postulated to..

Different corticosteroids and regimens for accelerating fetal lung maturation for babies at risk of preterm birth.

Myfanwy J Williams, Jenny A Ramson, Fiona C Brownfoot

Journal article  |  2022  |  Cochrane Database Syst Rev

BACKGROUND: Despite the widespread use of antenatal corticosteroids to prevent respiratory distress syndrome (RDS) in preterm infa..

Actions of Esomeprazole on the Maternal Vasculature in Lean and Obese Pregnant Mice with Impaired Nitric Oxide Synthesis: A Model of Preeclampsia

Natasha de Alwis, Natalie K Binder, Yeukai TM Mangwiro, Sally Beard, Natasha Pritchard, Elif Kadife, Bianca R Fato, Emerson Keenan, Fiona C Brownfoot, Tu'uhevaha J Kaitu'u-Lino, Natalie J Hannan

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preeclampsia is a devastating, multisystem disorder of pregnancy. It has no cure except delivery, which if premature can impart si..