Michelle Hansen

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease

Evelyn Tsantikos, Maverick Lau, Cassandra MN Castelino, Mhairi J Maxwell, Samantha L Passey, Michelle J Hansen, Narelle E McGregor, Natalie A Sims, Daniel P Steinfort, Louis B Irving, Gary P Anderson, Margaret L Hibbs

Journal article  |  2018  |  JOURNAL OF CLINICAL INVESTIGATION

Chronic obstructive pulmonary disease (COPD) is an incurable inflammatory lung disease that afflicts millions of people worldwide,..

Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease

Samantha L Passey, Michelle J Hansen, Steven Bozinovski, Christine F McDonald, Anne E Holland, Ross Vlahos

Journal article  |  2016  |  PHARMACOLOGY & THERAPEUTICS

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that constitutes a major global health burden. A signif..

Serum Amyloid A Induces Toll-Like Receptor 2-Dependent Inflammatory Cytokine Expression and Atrophy in C2C12 Skeletal Muscle Myotubes

Samantha L Passey, Steven Bozinovski, Ross Vlahos, Gary P Anderson, Michelle J Hansen

Journal article  |  2016  |  PLOS ONE

BACKGROUND: Skeletal muscle wasting is an important comorbidity of Chronic Obstructive Pulmonary Disease (COPD) and is strongly co..

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette-smoke-induced lung inflammation in mice

Steven Bozinovski, Huei Jiunn Seow, Sheau Pyng Jamie Chan, Desiree Anthony, Jonathan McQualter, Michelle Hansen, Brendan J Jenkins, Gary P Anderson, Ross Vlahos

Journal article  |  2015  |  CLINICAL SCIENCE

Cigarette smoke (CS) is the major cause of chronic obstructive pulmonary disease (COPD). Interleukin-17A (IL-17A) is a pivotal cyt..

TARGETING OXIDATIVE STRESS REDUCES CIGARETTE SMOKE-INDUCED LUNG INFLAMMATION AND WASTING IN MICE

I Bernardo, S Passey, H Seow, S Yatmaz, S Selemidis, S Bozinovski, M Hansen, R Vlahos

Conference Proceedings  |  2015  |  RESPIROLOGY

Targeting Oxidative Stress Reduces Cigarette Smoke-Induced Lung Inflammation And Wasting In Mice

R Vlahos, I Bernardo, S Passey, HJ Seow, S Yatmaz, S Selemidis, MJ Hansen, S Bozinovski

Conference Proceedings  |  2015  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IL-17A and Serum Amyloid A Are Elevated in a Cigarette Smoke Cessation Model Associated with the Persistence of Pigmented Macrophages, Neutrophils and Activated NK Cells

Michelle J Hansen, Sheau Pyng J Chan, Shenna Y Langenbach, Lovisa F Dousha, Jessica E Jones, Selcuk Yatmaz, Huei Jiunn Seow, Ross Vlahos, Gary P Anderson, Steven Bozinovski

Journal article  |  2014  |  PLOS ONE

While global success in cessation advocacy has seen smoking rates fall in many developed countries, persistent lung inflammation i..

SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling

Desiree Anthony, Jonathan L McQualter, Maria Bishara, Ee X Lim, Selcuk Yatmaz, Huei Jiunn Seow, Michelle Hansen, Michelle Thompson, John A Hamilton, Louis B Irving, Bruce D Levy, Ross Vlahos, Gary P Anderson, Steven Bozinovski

Journal article  |  2014  |  FASEB JOURNAL

Serum amyloid A (SAA) is expressed locally in chronic inflammatory conditions such as chronic obstructive pulmonary disease (COPD)..

The Lung Inflammation and Skeletal Muscle Wasting Induced by Subchronic Cigarette Smoke Exposure Are Not Altered by a High-Fat Diet in Mice

Michelle J Hansen, Hui Chen, Jessica E Jones, Shenna Y Langenbach, Ross Vlahos, Rosa C Gualano, Margaret J Morris, Gary P Anderson

Journal article  |  2013  |  PLOS ONE

Obesity and cigarette smoking independently constitute major preventable causes of morbidity and mortality and obesity is known to..

Dietary zinc mediates inflammation and protects against wasting and metabolic derangement caused by sustained cigarette smoke exposure in mice

Carol J Lang, Michelle Hansen, Eugene Roscioli, Jessica Jones, Chiara Murgia, Margaret Leigh Ackland, Peter Zalewski, Gary Anderson, Richard Ruffin

Journal article  |  2011  |  BIOMETALS

In mouse asthma models, inflammation can be modulated by zinc (Zn). Given that appetite loss, muscle wasting and poor nutrition ar..