Joses Nathanael

Oxidative damage of proline residues by nitrate radicals (NO3): a kinetic and product study

Joses G Nathanael, Jonathan M White, Annika Richter, Madison R Nuske, Uta Wille

Journal article  |  2020  |  Organic & Biomolecular Chemistry

Tertiary amides, such as in N-acylated proline or N-methyl glycine residues, react rapidly with nitrate radicals (NO3˙) with absol..

Reaction of Distonic Aryl and Alkyl Radical Cations with Amines: The Role of Charge and Spin Revealed by Mass Spectrometry, Kinetic Studies, and DFT Calculations

Benjamin Andrikopoulos, Parvinder K Sidhu, Bethany Taggert, Joses G Nathanael, Richard AJ O'Hair, Uta Wille

Journal article  |  2020  |  ChemPlusChem

Gas‐phase reaction of the aromatic distonic radical cations 4‐Pyr+. and 3‐Pyr+. with amines led to formation of the corresponding ..

Oxidative Damage in Aliphatic Amino Acids and Di- and Tripeptides by the Environmental Free Radical Oxidant NO3 center dot: The Role of the Amide Bond Revealed by Kinetic and Computational Studies

Joses G Nathanael, Uta Wille

Journal article  |  2019  |  The Journal of Organic Chemistry

Kinetic and computational data reveal a complex behavior of the important environmental free radical oxidant NO3• in its reactions..

The oxidative damage of biological molecules by air pollutants NO2● and NO3●

Joses Grady Nathanael

Thesis / Dissertation  |  2019

Air pollution is perceived as the world’s greatest environmental risk to human health. According to the World Health Organization ..

Amide Neighbouring-Group Effects in Peptides: Phenylalanine as Relay Amino Acid in Long-Distance Electron Transfer

Joses G Nathanael, Luke F Gamon, Meike Cordes, Paul R Rablen, Thomas Bally, Katharina M Fromm, Bernd Giese, Uta Wille

Journal article  |  2018  |  ChemBioChem

In nature, proteins serve as media for long-distance electron transfer (ET) to carry out redox reactions in distant compartments. ..

Reaction of Amino Acids, Di- and Tripeptides with the Environmental Oxidant NO3 center dot: A Laser Flash Photolysis and Computational Study

Joses G Nathanael, Amber N Hancock, Uta Wille

Journal article  |  2016  |  Chemistry - An Asian Journal

Absolute rate coefficients for the reaction between the important environmental free radical oxidant NO3. and a series of N- and C..

Oxidation of cholesterol and O-protected derivatives by the environmental pollutant NO2 center dot

AN Zalewski, JG Nathanael, JM White, U Wille

Journal article  |  2016  |  Chemical Communications

Exposure of O-protected and free cholesterol to NO2˙ under exclusion of water leads to nitroimine nitrates through a non-radical m..

Fragmentation-Rearrangement of Peptide Backbones Mediated by the Air Pollutant NO2 center dot

Luke F Gamon, Joses G Nathanael, Bethany I Taggert, Fraser A Henry, Jana Bogena, Uta Wille

Journal article  |  2015  |  Chemistry - A European Journal

The fragmentation-rearrangement of peptide backbones mediated by nitrogen dioxide, NO2 (.) , was explored using di-, tri-, and tet..

Oxidative Repair of Pyrimidine Cyclobutane Dimers by Nitrate Radicals (NO3•): A Kinetic and Computational Study

Tomas Haddad, Joses Nathanael, Jonathan White, Uta Wille

Journal article  |  Chemistry

Pyrimidine cyclobutane dimers are hazardous DNA lesions formed upon exposure of DNA to UV light, which can be repaired through oxi..