David Martino

Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy.

Yuka Asai, David Martino, Thomas Eiwegger, Kari Nadeau, Gerard H Koppelman, Ann E Clarke, Young-Ae Lee, Edmond S Chan, Elinor Simons, Catherine Laprise, Bruce Mazer, Ingo Marenholz, Diana Royce, Susan J Elliott, Christine Hampson, Jennifer Gerdts, Aida Eslami, Lianne Soller, Jennie Hui, Meghan Azad, et al.

Journal article  |  2020  |  Allergy

Folate levels in pregnancy and offspring food allergy and eczema

John Molloy, Fiona Collier, Richard Saffery, Katrina J Allen, Jennifer J Koplin, Anne Louise Ponsonby, Mimi LK Tang, Alister C Ward, David Martino, David Burgner, John B Carlin, Sarath Ranganathan, Christos Symeonedies, Terence Dwyer, Peter Vuillermin

Journal article  |  2019  |  PEDIATRIC ALLERGY AND IMMUNOLOGY

BACKGROUND: High folate status in pregnancy has been implicated in the increased prevalence of allergic disease, but there are no ..

Genetic determinants of paediatric food allergy: A systematic review

Noor HA Suaini, Yichao Wang, Victoria X Soriano, David J Martino, Katrina J Allen, Justine A Ellis, Jennifer J Koplin

Journal article  |  2019  |  ALLERGY

BACKGROUND: The genetic determinants of food allergy have not been systematically reviewed. We therefore systematically reviewed t..

B-cell phenotype and function in infants with egg allergy

Melanie R Neeland, David J Martino, Thanh D Dang, Jennifer J Koplin, Rachel L Peters, Alexander Grishin, Shyamali C Dharmage, Mimi L Tang, Hugh A Sampson, Richard Saffery, Katrina J Allen

Journal article  |  2019  |  ALLERGY

Egg allergen specific IgE diversity predicts resolution of egg allergy in the population cohort HealthNuts

Thanh D Dang, Rachel L Peters, Jennifer J Koplin, Shyamali C Dharmage, Lyle C Gurrin, Anne-Louise Ponsonby, David J Martino, Melanie Neeland, Mimi LK Tang, Katrina J Allen

Journal article  |  2019  |  ALLERGY

BACKGROUND: IgE-mediated egg allergy presents as one of the most common food allergies in children. Measurement of egg white speci..

Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early Childhood

Noor HA Suaini, Jennifer J Koplin, Rachel L Peters, Mari Sasaki, Justine A Ellis, David J Martino, Adrian J Lowe, Mimi LK Tang, Anne-Louise Ponsonby, Lyle C Gurrin, Shyamali C Dharmage, Katrina J Allen

Journal article  |  2019  |  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

BACKGROUND: We previously reported that infants with Asian-born parents are 3 times more likely to have IgE-mediated food allergy ..

Epigenetic mechanisms in food allergy

DJ Martino

Book Chapter  |  2019

Community rates of food allergy have been rising over the last 25 years at a rate too rapid to be explained by changes in genetics..

Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children

Line Hjort, David Martino, Louise Groth Grunnet, Haroon Naeem, Jovana Maksimovic, Anders Henrik Olsson, Cuilin Zhang, Charlotte Ling, Sjurdur Frodi Olsen, Richard Saffery, Allan Arthur Vaag

Journal article  |  2018  |  JCI INSIGHT

Offspring of women with gestational diabetes mellitus (GDM) are at increased risk of developing metabolic disease, potentially med..

Early life innate immune signatures of persistent food allergy

Melanie R Neeland, Jennifer J Koplin, Thanh D Dang, Shyamali C Dharmage, Mimi L Tang, Susan L Prescott, Richard Saffery, David J Martino, Katrina J Allen

Journal article  |  2018  |  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

BACKGROUND: Food allergy naturally resolves in a proportion of food-allergic children without intervention; however the underlying..

Epigenetic dysregulation of naive CD4 T-cell activation genes in childhood food allergy

David Martino, Melanie Neeland, Thanh Dang, Joanna Cobb, Justine Ellis, Alice Barnett, Mimi Tang, Peter Vuillermin, Katrina Allen, Richard Saffery

Journal article  |  2018  |  NATURE COMMUNICATIONS

Food allergy poses a significant clinical and public health burden affecting 2-10% of infants. Using integrated DNA methylation an..