Joanne Ryan

The long-term consequences of trauma and posttraumatic stress disorder symptoms on later life cognitive function and dementia risk.

Dinuli Nilaweera, Rosanne Freak-Poli, Karen Ritchie, Isabelle Chaudieu, Marie-Laure Ancelin, Joanne Ryan

Journal article  |  2020  |  Psychiatry Res

Stress may be a risk factor for dementia, however it is unknown whether post-traumatic stress disorder (PTSD) symptoms are associa..

Long-Term Blood Pressure Variability and Risk of Cardiovascular Disease Events Among Community-Dwelling Elderly.

Michael E Ernst, Enayet K Chowdhury, Lawrence J Beilin, Karen L Margolis, Mark R Nelson, Rory Wolfe, Andrew M Tonkin, Joanne Ryan, Robyn L Woods, John J McNeil, Christopher M Reid, undefined ASPREE Investigator Group

Journal article  |  2020  |  Hypertension

High office blood pressure variability (OBPV) in midlife increases the risk of cardiovascular disease (CVD), but the impact of OBP..

Quality of life and mortality in the general population: a systematic review and meta-analysis.

Aung Zaw Zaw Phyo, Rosanne Freak-Poli, Heather Craig, Danijela Gasevic, Nigel P Stocks, David A Gonzalez-Chica, Joanne Ryan

Journal article  |  2020  |  BMC Public Health

BACKGROUND: Quality of life (QoL) is multi-dimensional concept of an individual' general well-being status in relation to their va..

Long-term Blood Pressure Variability And Cognitive Decline And Dementia Among Community-dwelling Elderly.

Michael E Ernst, Joanne Ryan, Enayet K Chowdhury, Anne M Murray, Robyn L Woods, Suzanne G Orchard, Rory Wolfe, Elsdon Storey, Raj C Shah, Andrew Tonkin, Christopher M Reid

Conference Proceedings  |  2020  |  HYPERTENSION

Greater blood pressure variability (BPV) in midlife increases the risk of dementia, but the impact of BPV in cognitively intact ol..

Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline.

Joanne Ryan, Elsdon Storey, Anne M Murray, Robyn L Woods, Rory Wolfe, Christopher M Reid, Mark R Nelson, Trevor TJ Chong, Jeff D Williamson, Stephanie A Ward, Jessica E Lockery, Suzanne G Orchard, Ruth Trevaks, Brenda Kirpach, Anne B Newman, Michael E Ernst, John J McNeil, Raj C Shah, undefined ASPREE Investigator Group

Journal article  |  2020  |  Neurology

OBJECTIVE: To determine the effect of low-dose aspirin vs placebo on incident all-cause dementia, incident Alzheimer disease (AD),..

Adolescent and young adult mental health problems and infant offspring behavior: Findings from a prospective intergenerational cohort study

Primrose Letcher, Christopher J Greenwood, Helena Romaniuk, Elizabeth Spry, Jacqui A Macdonald, Helena McAnally, Kimberly C Thomson, George Youssef, Delyse Hutchinson, Jennifer McIntosh, Ann Sanson, Joanne Ryan, Ben Edwards, Judith Sligo, Robert J Hancox, George C Patton, Craig A Olsson

Journal article  |  2020  |  JOURNAL OF AFFECTIVE DISORDERS

BACKGROUND: Parental depression and anxiety have been consistently linked to offspring behavior problems across childhood. However..

HIF3Acord blood methylation and systolic blood pressure at 4 years - a population-based cohort study

Toby Mansell, David Burgner, Anne-Louise Ponsonby, Fiona Collier, Angela Pezic, Peter Vuillermin, Markus Juonala, Joanne Ryan, Richard Saffery

Journal article  |  2020  |  EPIGENETICS

Methylation levels at the hypoxia-inducible factor 3α gene (HIF3A) in blood have been linked to body mass index (BMI) in adults. D..

The role of glucocorticoid and mineralocorticoid receptor DNA methylation in antenatal depression and infant stress regulation

Megan Galbally, Stuart J Watson, Marinus van IJzendoorn, Richard Saffery, Joanne Ryan, Edo Ronald de Kloet, Tim F Oberlander, Martha Lappas, Andrew J Lewis

Journal article  |  2020  |  PSYCHONEUROENDOCRINOLOGY

Understanding fetal programming pathways that underpin the relationship between maternal and offspring mental health necessitates ..

Maternal mental health and infant emotional reactivity: a 20-year two-cohort study of preconception and perinatal exposures

Elizabeth Spry, Margarita Moreno-Betancur, Denise Becker, Helena Romaniuk, John B Carlin, Emma Molyneaux, Louise M Howard, Joanne Ryan, Primrose Letcher, Jennifer McIntosh, Jacqui A Macdonald, Christopher J Greenwood, Kimberley C Thomson, Helena McAnally, Robert Hancox, Delyse M Hutchinson, George J Youssef, Craig A Olsson, George C Patton

Journal article  |  2020  |  PSYCHOLOGICAL MEDICINE

BACKGROUND: Maternal mental health during pregnancy and postpartum predicts later emotional and behavioural problems in children. ..

Methylation of the LEP gene promoter in blood at 12 months and BMI at 4 years of age-a population-based cohort study

Toby Mansell, Anne-Louise Ponsonby, Fiona Collier, David Burgner, Angela Pezic, Peter Vuillermin, Joanne Ryan, Richard Saffery

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF OBESITY

Increasing evidence links epigenetic variation to anthropometric and metabolic measures. Leptin signalling regulates appetite and ..