David Curtis

Cellular distribution of IDH mutations in AML during morphologic remission.

Radha Ramanan, Ing Soo Tiong, Adam Ivey, Doen Ming Ong, Fiona C Brown, Chyn Chua, Tongted Das, David J Curtis

Journal article  |  2023  |  Leuk Res

Limited information exists about the cellular distribution of mutations which persist in remission in acute myeloid leukemia (AML)..

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Feng Yan, Cedric Tremblay, Francine Garret-Bakelman, Jesslyn Saw, Matthew P McCormack, Shokoufeh Abdollahi, Pieter Van Vlierberghe, David Powell, Nicholas C Wong, David J Curtis

Journal article  |  2022  |  Blood

PB2176: AN AUSTRALIAN/NEW ZEALAND RANDOMIZED TRIAL OF POST-TRANSPLANT CYCLOPHOSPHAMIDE IN MATCHED RELATED PERIPHERAL BLOOD STEM CELL TRANSPLANTS FOR ACUTE LEUKAEMIA OR MYELODYSPLASIA – ALLG BM12

D Curtis, S Patil, D Purtill, D Ritchie, D Yeung, C Lewis, E Wong, J Moore, T Perera, M King, R De Abreu Lourenco, O Morrissey, G Hill, J Reynolds, S Tey, D Gottlieb

Journal article  |  2022  |  HemaSphere

Good Engraftment but Quality and Donor Concerns for Cryopreserved Hemopoietic Progenitor Cell Products Collected During the COVID-19 Pandemic

Duncan Purtill, Cheryl Hutchins, Glen Kennedy, Andrea McClean, Chris Fraser, Peter J Shaw, Paul Chiappini, Helen Tao, David DF Ma, Karieshma Kabani, Lijun Bai, Matthew Greenwood, Ashish Bajel, Elizabeth O'Flaherty, David J Curtis, Leanne Purins, Travis Perera, Sarah Tan, Andrew Butler, Ken Micklethwaite, et al.

Journal article  |  2021  |  TRANSPLANTATION AND CELLULAR THERAPY

Changes to donor availability, collection center capacity, and travel restrictions during the early phase of the COVID-19 pandemic..

Shutting the gate: targeting endocytosis in acute leukemia

Cedric S Tremblay, Stephen B Ting, Adam McCluskey, Phillip J Robinson, David J Curtis

Journal article  |  2021  |  EXPERIMENTAL HEMATOLOGY

Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular..

Peripheral Blood Haploidentical Allogeneic Stem Cell Transplantation in Older Adults with AML/MDS Demonstrates Excellent Long Term Overall Survival, Results from the Australasian Bone Marrow Transplant Recipient Registry

Edward Abadir, Jad Othman, John Kwan, David J Gottlieb, Glen A Kennedy, Ashish Bajel, Richard Doocey, Travis Perera, Anne-Marie Watson, Peter G Bardy, Matthew Greenwood, David J Curtis, Steven Tran, John Moore, Nada Hamad

Journal article  |  2021  |  Blood

Abstract Background: Haploidentical Hematopoietic Stem Cell Transplantation (Haplo-HCT) is an established therapy u..

Outcomes of non-myeloablative allogeneic stem cell transplant in older patients with acute myeloid leukaemia in first remission

Phillip C Nguyen, Kate Manos, Chun Y Fong, Anthony P Schwarer, Ing S Tiong, Andrew H Wei, David Kliman, David J Curtis

Journal article  |  2021  |  INTERNAL MEDICINE JOURNAL

The benefits of non-myeloablative stem cell transplant in older patients with acute myeloid leukaemia are unclear. We compare the ..

Author Correction: Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells.

Cedric S Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M Salmon, Adam McCluskey, Richard B Lock, Phillip J Robinson, Stephen M Jane, David J Curtis

Journal article  |  2021  |  Nat Commun

In the original version of this Article, contributions from Jennifer R. Baker and Cecilia C. Russell from the University of Newcas..

T-ALL can evolve to oncogene independence

Hesham Abdulla, Anh Vo, Benjamin J Shields, Tenae J Davies, Jacob T Jackson, Raed Alserihi, Elizabeth M Viney, Tin Wong, Feng Yan, Nicholas C Wong, Lisa Demoen, David J Curtis, Warren S Alexander, Pieter Van Vlierberghe, Ross A Dickins, Matthew P McCormack

Journal article  |  2021  |  LEUKEMIA

The majority of cases of T-cell acute lymphoblastic leukemia (T-ALL) contain chromosomal abnormalities that drive overexpression o..

Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Avani Yeola, Shruthi Subramanian, Rema A Oliver, Christine A Lucas, Julie A Thoms, Feng Yan, Jake Olivier, Diego Chacon, Melinda L Tursky, Pallavi Srivastava, Jason R Potas, Tzongtyng Hung, Carl Power, Philip Hardy, David D Ma, Kristopher A Kilian, Joshua McCarroll, Maria Kavallaris, Luke B Hesson, Dominik Beck, et al.

Journal article  |  2021  |  SCIENCE ADVANCES

Terminally differentiated murine osteocytes and adipocytes can be reprogrammed using platelet-derived growth factor-AB and 5-azacy..