Holly Chinnery

Morphometric Changes to Corneal Dendritic Cells in Individuals With Mild Cognitive Impairment

Cirous Dehghani, Shaun Frost, Rajiv Jayasena, Christopher Fowler, Colin L Masters, Yogesan Kanagasingam, Haihan Jiao, Jeremiah KH Lim, Holly R Chinnery, Laura E Downie

Journal article  |  2020  |  Frontiers in Neuroscience

Purpose: There has been increasing interest in identifying non-invasive, imaging biomarkers for neurodegenerative disorders of the..

The effect of high-fat diet-induced metabolic disturbance on corneal neuroimmune features

Haihan Jiao, Alicia SL Lim, Therese E Fazio Coles, Rachel M McQuade, John B Furness, Holly R Chinnery

Journal article  |  2020  |  Experimental Eye Research

PURPOSE: The highly innervated cornea is susceptible to nerve loss secondary to systemic diseases such as diabetes and metabolic d..

In vivo immune cell dynamics in the human cornea

Luisa H Colorado, Katie Edwards, Holly R Chinnery, Haydee E Bazan

Journal article  |  2020  |  Experimental Eye Research

In vivo confocal microscopy (IVCM) allows the evaluation of the living human cornea at the cellular level. The non-invasive nature..

Retinal Functional and Structural Changes in the 5xFAD Mouse Model of Alzheimer's Disease

Jeremiah KH Lim, Qiao-Xin Li, Zheng He, Algis J Vingrys, Holly R Chinnery, Jamie Mullen, Bang V Bui, Christine TO Nguyen

Journal article  |  2020  |  Frontiers in Neuroscience

Alzheimer's disease is characterized by the aberrant deposition of protein in the brain and is the leading cause of dementia world..

Corneal Epithelial "Neuromas": A Case of Mistaken Identity?

Mary Ann Stepp, Sonali Pal-Ghosh, Laura E Downie, Alexis Ceecee Zhang, Holly R Chinnery, Joshua Machet, Nick Di Girolamo

Journal article  |  2020  |  Cornea

Laser scanning in vivo confocal microscopy is a useful clinical tool to assess the corneal nerves in human and laboratory animals...

The neuroregenerative effects of topical decorin on the injured mouse cornea.

Mengliang Wu, Laura E Downie, Liam M Grover, Richard JA Moakes, Saaeha Rauz, Ann Logan, Haihan Jiao, Lisa J Hill, Holly R Chinnery

Journal article  |  2020  |  Journal of Neuroinflammation

BACKGROUND: The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any ..

Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy

Haihan Jiao, Laura E Downie, Xin Huang, Mengliang Wu, Sara Oberrauch, Ryan J Keenan, Laura H Jacobson, Holly R Chinnery

Journal article  |  2020  |  Journal of Neuroinflammation

BACKGROUND: Tauopathy in the central nervous system (CNS) is a histopathological hallmark of frontotemporal dementia (FTD) and Alz..

Tunneling Nanotubes and the Eye: Intercellular Communication and Implications for Ocular Health and Disease

Holly R Chinnery, Kate E Keller

Journal article  |  2020  |  BioMed Research International

Ocular Phenotype of Relaxin Gene Knockout (Rln(-/-)) Mice

Ulrike Hampel, Holly R Chinnery, Fabian Garreis, Friedrich Paulsen, Robb de Iongh, Bang Bui, Christine Nguyen, Laura Parry, Huei Leo Chen

Journal article  |  2020  |  Current Eye Research

Material, Immunological, and Practical Perspectives on Eye Drop Formulation

Naomi H Bennett, Holly R Chinnery, Laura E Downie, Lisa J Hill, Liam M Grover

Journal article  |  2020  |  Advanced Functional Materials