Holly Chinnery

Topical Decorin Reduces Corneal Inflammation and Imparts Neuroprotection in a Mouse Model of Benzalkonium Chloride-induced Corneal Neuropathy.

Mengliang Wu, Laura E Downie, Lisa J Hill, Holly R Chinnery

Journal article  |  2023  |  Invest Ophthalmol Vis Sci

PURPOSE: We evaluated the neuroprotective and immunomodulatory effects of topical decorin in a murine model of benzalkonium chlori..

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

Mengliang Wu, Lisa J Hill, Laura E Downie, Holly R Chinnery

Journal article  |  2022  |  PROGRESS IN RETINAL AND EYE RESEARCH

In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with their important roles in the mainte..

Developing culturally safe education practices in optometry schools across Australia and Aotearoa New Zealand

Nicola S Anstice, Khyber Alam, James A Armitage, Brett Biles, Joanna M Black, Mei Ying Boon, Teah Carlson, Holly R Chinnery, Andrew Collins, Anthea Cochrane, Debbie Duthie, Shelley Hopkins, Gary Fitzpatrick, Lisa Keay, Renata Watene, Aryati Yashadhana, Sharon A Bentley

Journal article  |  2022  |  CLINICAL AND EXPERIMENTAL OPTOMETRY

Access to culturally safe health services is a basic human right, however through the lasting effects of colonisation, oppression,..

Topographical Distribution and Phenotype of Resident Meibomian Gland Orifice Immune Cells (MOICs) in Mice and the Effects of Topical Benzalkonium Chloride (BAK)

Ching Yi Wu, Mengliang Wu, Xin Huang, Ben J Gu, Carole Maldonado-Codina, Philip B Morgan, Laura E Downie, Holly R Chinnery

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Meibomian gland orifices (MGOs) are located along the eyelid margin and secrete meibum into the tear film. The profile of resident..

Defining an Optimal Sample Size for Corneal Epithelial Immune Cell Analysis Using in vivo Confocal Microscopy Images

Xin Yuan Zhang, Mengliang Wu, Holly R Chinnery, Laura E Downie

Journal article  |  2022  |  FRONTIERS IN MEDICINE

PURPOSE: In vivo confocal microscopy (IVCM) images are frequently used to quantify corneal epithelial immune cell (IC) density in ..

Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface

Joon Keit Loi, Yannick O Alexandre, Kirthana Senthil, Dominik Schienstock, Sarah Sandford, Sapna Devi, Susan N Christo, Laura K Mackay, Holly R Chinnery, Peregrine B Osborne, Laura E Downie, Erica K Sloan, Scott N Mueller

Journal article  |  2022  |  CELL REPORTS

The eye is considered immune privileged such that immune responses are dampened to protect vision. As the most anterior compartmen..

The effect of topical decorin on temporal changes to corneal immune cells after epithelial abrasion

Mengliang Wu, Laura E Downie, Lisa J Hill, Holly R Chinnery

Journal article  |  2022  |  JOURNAL OF NEUROINFLAMMATION

BACKGROUND: Corneal immune cells interact with corneal sensory nerves during both homeostasis and inflammation. This study sought ..

Corneal immune cell morphometry as an indicator of local and systemic pathology: A review

Holly R Chinnery, Xin Yuan Zhang, Ching Yi Wu, Laura E Downie

Journal article  |  2021  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The corneal epithelium contains a population of resident immune cells commonly referred to as dendritic cells (DCs), or Langerhans..

Distribution of Corneal TRPV1 and Its Association With Immune Cells During Homeostasis and Injury

Haihan Jiao, Jason J Ivanusic, Paul G McMenamin, Holly R Chinnery

Journal article  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

PURPOSE: Given the role of corneal sensory nerves during epithelial wound repair, we sought to examine the relationship between im..

The effect of topical decorin on corneal immune cell dynamics after epithelial abrasion

Mengliang Wu, Laura Downie, Lisa Hill, Holly Chinnery

Conference Proceedings  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE